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Multiple sclerosis dysphagia

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https://www.readbyqxmd.com/read/29055467/diagnostic-evaluation-of-dysphagia-in-multiple-sclerosis-patients-using-a-persian-version-of-dymus-questionnaire
#1
Sahar Danesh Pajouh, Negin Moradi, Mohammad Jafar Shaterzadeh Yazdi, Seyed Mahmoud Latifi, Mohammad Mehravar, Nastaran Majdinasab, Ali Reza Olapour, Majid Soltani, Fatemeh Khanchezar
BACKGROUND: Multiple sclerosis is a chronic neurological disease that may cause swallowing disorders. Dysphagia is a common problem, which patients with different levels of disability may encounter, but it is usually underestimated; therefore, effective assessments need to be performed before any serious complications. The aim of this study was to identify the frequency and characteristics of dysphagia in multiple sclerosis patients of Khuzestan MS society, using a Persian version of Dysphagia in Multiple Sclerosis (DYMUS) questionnaire...
October 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28845104/gastrointestinal-manifestations-associated-with-systemic-sclerosis-results-from-the-nationwide-inpatient-sample
#2
Yaseen Alastal, Tariq A Hammad, Anas Renno, Basmah Khalil, Joel Pierre, Bismark Kwaah, Sadik A Khuder, Ali Nawras
BACKGROUND: Systemic sclerosis (SSc) is a multisystem disease associated with significant morbidity and increased mortality. The prevalence of different gastrointestinal (GI) manifestations has been investigated in multiple, but mainly small, retrospective studies. In this study, we investigated the prevalence and risk for a broad spectrum of GI disorders and malignancies in a large sample of inpatients with SSc in the United States. METHODS: We conducted a retrospective analysis using the 2010-2011 Healthcare Cost and Utilization Project - Nationwide Inpatient Sample (HCUP-NIS)...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28819801/botulinum-toxin-treatment-in-multiple-sclerosis-a-review
#3
REVIEW
Yasaman Safarpour, Tahereh Mousavi, Bahman Jabbari
Purpose of review The purpose of this review is to provide updated information on the role of botulinum neurotoxin (BoNT) therapy in multiple sclerosis (MS). This review aims to answer which symptoms of multiple sclerosis may be amenable to BoNT therapy. Recent findings We searched the literature on the efficacy of BoNTs for treatment of MS symptoms up to April 1st 2017 via the Yale University Library's search engine including but not limited to Pub Med and Ovis SP. The level of efficacy was defined according to the assessment's criteria set forth by the Subcommittee on Guideline Development of the American Academy of Neurology...
August 17, 2017: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/28281365/seasons-and-als-time-of-death
#4
Susana Pinto, Mamede De Carvalho
INTRODUCTION: Respiratory complications are the main cause of death in amyotrophic lateral sclerosis (ALS). Season-associated-death risk was not addressed before. OBJECTIVE: To assess month/season-associated death risk in ALS. METHODS: We included all patients followed in our unit who died before 1 January 2016, excluding those with uncertain information. A χ(2) test assessed differences between months/seasons. A two-step cluster analysis explored the significant survival independent factors...
March 10, 2017: Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
https://www.readbyqxmd.com/read/28276076/managing-the-oral-side-effects-of-medications-used-to-treat-multiple-sclerosis
#5
N Cockburn, K Pateman, M W Taing, A Pradhan, P J Ford
BACKGROUND: Many medications used to manage multiple sclerosis (MS) affect oral health. This review aimed to identify the oral side-effects of the current drugs recommended in Australia to treat MS and make dental practitioners aware of the range of symptoms. METHODS: The Australian Therapeutic Guidelines and the Australian Medicines Handbook were searched for medications used to treat MS. For each medication, the generic name, class, route of administration, dosage and drug company reported side-effects were extracted from the online Monthly Index of Medical Specialties (MIMs) database...
September 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28275351/botulinum-toxin-is-effective-in-the-management-of-neurogenic-dysphagia-clinical-electrophysiological-findings-and-tips-on-safety-in-different-neurological-disorders
#6
Enrico Alfonsi, Domenico A Restivo, Giuseppe Cosentino, Roberto De Icco, Giulia Bertino, Antonio Schindler, Massimiliano Todisco, Mauro Fresia, Andrea Cortese, Paolo Prunetti, Matteo C Ramusino, Arrigo Moglia, Giorgio Sandrini, Cristina Tassorelli
Background and Aims: Neurogenic dysphagia linked to failed relaxation of the upper esophageal sphincter (UES) can be treated by injecting botulinum toxin (BTX) into the cricopharyngeal (CP) muscle. We compared the effects of this treatment in different neurological disorders with dysphagia, to evaluate its efficacy over time including the response to a second injection. Materials and Methods: Sixty-seven patients with neurogenic dysphagia associated with incomplete or absent opening of the UES (24 with brainstem or hemispheric stroke, 21 with parkinsonian syndromes, 12 with multiple sclerosis, and 10 with spastic-dystonic syndromes secondary to post-traumatic encephalopathy) were treated with the injection of IncobotulinumtoxinA (dose 15-20 U) into the CP muscle under electromyographic guidance...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28252325/a-team-approach-to-supporting-the-nutritional-needs-of-patients-living-with-multiple-sclerosis
#7
REVIEW
Nicola Bell, Lorna Brammer
Multiple sclerosis is the most common cause of non-traumatic disability in young adults, with most diagnoses occurring between the ages of 25-49 years. Nutrition must be managed effectively and holistically to improve health and quality of life. Dysphagia management is collaborative and can enhance nutrition and hydration goals as well as reduce the risk of aspiration pneumonia. A case study demonstrates the specialist clinical skills and frameworks used to achieve nutrition, hydration, safety and patient focused outcomes...
March 2, 2017: British Journal of Community Nursing
https://www.readbyqxmd.com/read/27865707/a-comprehensive-database-of-published-tdcs-clinical-trials-2005-2016
#8
REVIEW
Jean-Pascal Lefaucheur
Transcranial direct current stimulation (tDCS) is a technique of noninvasive cortical stimulation allowing significant modification of brain functions. Clinical application of this technique was reported for the first time in March 2005. This paper presents a detailed list of the 340 articles (excluding single case reports) which have assessed the clinical effect of tDCS in patients, at least when delivered to cortical targets. The reviewed conditions were: pain syndromes, Parkinson's disease, dystonia, cerebral palsy, post-stroke limb motor impairment, post-stroke neglect, post-stroke dysphagia, post-stroke aphasia, primary progressive aphasia, multiple sclerosis, epilepsy, consciousness disorders, Alzheimer's disease and other types of dementia, tinnitus, depression, auditory hallucinations and negative symptoms of schizophrenia, addiction and craving, autism, and attention disorders...
December 2016: Neurophysiologie Clinique, Clinical Neurophysiology
https://www.readbyqxmd.com/read/27802825/mog-igg-in-nmo-and-related-disorders-a-multicenter-study-of-50-patients-part-3-brainstem-involvement-frequency-presentation-and-outcome
#9
MULTICENTER STUDY
Sven Jarius, Ingo Kleiter, Klemens Ruprecht, Nasrin Asgari, Kalliopi Pitarokoili, Nadja Borisow, Martin W Hümmert, Corinna Trebst, Florence Pache, Alexander Winkelmann, Lena-Alexandra Beume, Marius Ringelstein, Oliver Stich, Orhan Aktas, Mirjam Korporal-Kuhnke, Alexander Schwarz, Carsten Lukas, Jürgen Haas, Kai Fechner, Mathias Buttmann, Judith Bellmann-Strobl, Hanna Zimmermann, Alexander U Brandt, Diego Franciotta, Kathrin Schanda, Friedemann Paul, Markus Reindl, Brigitte Wildemann
BACKGROUND: Myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) are present in a subset of aquaporin-4 (AQP4)-IgG-negative patients with optic neuritis (ON) and/or myelitis. Little is known so far about brainstem involvement in MOG-IgG-positive patients. OBJECTIVE: To investigate the frequency, clinical and paraclinical features, course, outcome, and prognostic implications of brainstem involvement in MOG-IgG-positive ON and/or myelitis. METHODS: Retrospective case study...
November 1, 2016: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/27681479/how-do-australians-living-with-ms-experience-oral-health-and-accessing-dental-care-a-focus-group-study
#10
K Pateman, N Cockburn, J Campbell, P J Ford
OBJECTIVES: The symptoms of multiple sclerosis (MS) can affect oral care and access to dental services, but there is limited literature describing the oral health and perceived oral healthcare needs of people with MS. This study aimed to explore the oral health experiences, oral health behaviours and barriers to accessing dental care perceived by people living with MS in Australia. METHODS: Six focus groups were held across two metropolitan areas (Brisbane, Queensland and Melbourne, Victoria) and one regional area (Toowoomba, Queensland)...
September 28, 2016: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/27488370/treatment-effects-for-dysphagia-in-adults-with-multiple-sclerosis-a-systematic-review
#11
REVIEW
Dalal Alali, Kirrie Ballard, Hans Bogaardt
Dysphagia or swallowing difficulties have been reported to be a concern in adults with multiple sclerosis (MS). This problem can result in several complications including aspiration pneumonia, reduced quality of life and an increase in mortality rate. No previous systematic reviews on treatment effects for dysphagia in MS have been published. The main objective of this study is to summarise and qualitatively analyse published studies on treatment effects for dysphagia in MS. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines were applied to conduct a systematic search of seven databases, using relevant key words, and subsequent analysis of the identified studies...
October 2016: Dysphagia
https://www.readbyqxmd.com/read/27048665/a-systematic-review-of-patient-or-proxy-reported-validated-instruments-assessing-pediatric-dysphagia
#12
REVIEW
Charles M Myer, Rebecca J Howell, Aliza P Cohen, J Paul Willging, Stacey L Ishman
OBJECTIVE: Pediatric dysphagia occurs in 500,000 children each year; however, there is not a common tool to assess these children. Our aim was to identify validated patient- or parent-reported outcome assessment tools evaluating pediatric dysphagia. DATA SOURCES: Scopus, EMBASE, PubMed, Cochrane Library, and CINAHL electronic databases (all indexed years through August 2014). REVIEW METHODS: Inclusion criteria included English-language articles containing instruments evaluated in children...
May 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/26946707/-neurology
#13
Arseny A Sokolov, Andrea O Rossetti, Patrik Michel, David Benninger, Bernard Nater, Christian Wider, Lorenz Hirt, Thierry Kuntzer, Jean-François Démonet, Renaud A Du Pasquier, François Vingerhoets
In 2015, cerebral stimulation becomes increasingly established in the treatment of pharmacoresistant epilepsy. Efficacy of endovascular treatment has been demonstrated for acute ischemic stroke. Deep brain stimulation at low frequency improves dysphagia and freezing of gait in Parkinson patients. Bimagrumab seems to increase muscular volume and force in patients with inclusion body myositis. In cluster-type headache, a transcutaneous vagal nerve stimulator is efficient in stopping acute attacks and also reducing their frequency...
January 13, 2016: Revue Médicale Suisse
https://www.readbyqxmd.com/read/26323455/orthognathic-surgery-in-a-patient-with-multiple-sclerosis
#14
Saleh A Al-Bazie
AIM: The aim of this paper was to report a case of orthognathic surgery successfully done in a patient with multiple sclerosis. BACKGROUND: Multiple sclerosis (MS) is a chronic, progressive inflammatory disorder of the central nervous system affecting young adults, characterized by lymphocytic infiltration of the brain and spinal cord leading to demyelination and focal axonal damage. Clinically, MS patients present with reversible neurological dysfunction in the early stages, which progresses to irreversible neurological disability and deficit...
June 1, 2015: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/26205436/esophageal-involvement-in-multiple-system-atrophy
#15
Hiroshige Taniguchi, Hideaki Nakayama, Kazuhiro Hori, Masatoyo Nishizawa, Makoto Inoue, Takayoshi Shimohata
The prevalence of esophageal involvement and its impact on clinical manifestations in patients with multiple system atrophy (MSA) remains unknown. We recruited 16 consecutive patients with dysphagia associated with MSA (MSA group) and 16 consecutive patients with dysphagia associated with amyotrophic lateral sclerosis (ALS group). We assessed the presence or absence of food stagnation within the esophagus using videofluorography. Food stagnation within the esophagus was observed in 16 patients (100 %; 7 severe, 9 mild) in the MSA group and in 4 patients (25 %; 4 mild) in the ALS group (P < 0...
December 2015: Dysphagia
https://www.readbyqxmd.com/read/26011834/prophylactic-percutaneous-endoscopic-gastrostomy-peg-the-importance-of-nutritonal-support-in-patients-with-head-and-neck-cancers-hncs-or-neurogenic-dysphagia-nd
#16
D Cristian, A Poalelungi, A Anghel, T Burcoş, R Grigore, S Berteşteanu, G Richiteanu, F Grama
BACKGROUND: We evaluated the effectiveness and safety of prophylactic PEG performed for the enteral nutrition support during the oncological treatment of patients with HNCs and as a part of the management of neurological patients experiencing neurogenic dysphagia. METHODS: In 2013 we followed up on a group of 23 HNC patients subjected to prophylactic PEG. We assessed the duration of the procedure, intraprocedural incidents and their causes, time to tube-refeeding and discharge after intervention, post interventional analgesia, early and late complications,toleration, costs and postoperative course of these patients after radical surgery maintaining PEG in place...
March 2015: Chirurgia
https://www.readbyqxmd.com/read/25687968/electrophysiological-evaluation-of-dysphagia-in-the-mild-or-moderate-patients-with-multiple-sclerosis-a-concept-of-subclinical-dysphagia
#17
Yesim Beckmann, Nevin Gürgör, Ahmet Çakır, Şehnaz Arıcı, Tülay Kurt İncesu, Yaprak Seçil, Cumhur Ertekin
Swallowing mechanism and neurogenic dysphagia in MS have been rarely studied by electromyographical (EMG) methods. This study aims to evaluate the presence of subclinical dysphagia in patients with mild multiple sclerosis (MS) using electrophysiological methods. A prospective study of 51 patients with relapsing remitting multiple sclerosis and 18 age-matched healthy adults was investigated. We used electromyography to measure the activity of the submental muscles during swallowing. Electrophysiological recordings of patients were obtained during relapse, after relapse, and at any time in remission period...
June 2015: Dysphagia
https://www.readbyqxmd.com/read/25647290/prevalence-of-dysphagia-in-multiple-sclerosis-a-systematic-review-and-meta-analysis
#18
REVIEW
Xiao-Li Guan, Hui Wang, Hai-Shan Huang, Ling Meng
Although dysphagia was recognized as a clinical finding in multiple sclerosis (MS) as early as 1877, it has not received enough attention yet. With the progress of diagnostic method for dysphagia, there has been a rapid development in estimating the prevalence of deglutition disorder in MS. In this review, we aimed to conduct a systematic review and meta-analysis of published literature to establish the prevalence of dysphagia in multiple sclerosis. We systematically searched Embase, PubMed databases and Cochrane library from 1980 to August 2014, supplemented by hand searching to identify relevant studies...
May 2015: Neurological Sciences
https://www.readbyqxmd.com/read/25601606/natural-compounds-used-as-therapies-targeting-to-amyotrophic-lateral-sclerosis
#19
REVIEW
Seyed F Nabavi, Maria Daglia, Giuseppe D'Antona, Eduardo Sobarzo-Sánchez, Zeliha S Talas, Seyed M Nabavi
Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease that occurs throughout the world with no racial, ethnic or socioeconomic boundaries. Despite its high morbidity and mortality, there are limited medications available for ALS that may increase survival in patients with amyotrophic lateral sclerosis by approximately 2-3 months. Inasmuch as negative effects of riluzole on muscle atrophy and wasting, weakness, muscle spasticity, dysarthria, dysphagia, and overall patient quality of life and its different adverse effects, much attention has been paid to natural products and herbal medicines...
2015: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/25332860/potential-effect-of-sildenafil-beyond-pulmonary-hypertension-in-a-patient-with-diffuse-systemic-sclerosis-and-cryoglobulinemic-vasculitis
#20
Tamer A Gheita, Hussam Ammar, Sanaa A Kenawy
INTRODUCTION: Pulmonary arterial hypertension (PAH) is a serious complication of systemic sclerosis (SSc), has a dramatic impact on prognosis and survival and is a leading cause of death. CASE DESCRIPTION: A 40 years old female patient with difuse cutaneous SSc (dcSSc) presented with progressive dyspnea, choking sensation, cough, abdominal distension, constipation and dysphagia to solids. The muscle power was mildly reduced and multiple purpuric eruptions were present on the legs of variable sizes...
2014: SpringerPlus
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