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Reshma jagsi

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https://www.readbyqxmd.com/read/28332033/surgeon-attitudes-and-use-of-mri-in-patients-newly-diagnosed-with-breast-cancer
#1
Monica Morrow, Sarah T Hawley, M Chandler McLeod, Ann S Hamilton, Kevin C Ward, Steven J Katz, Reshma Jagsi
BACKGROUND: Usage of magnetic resonance imaging (MRI) in newly diagnosed breast cancer patients is increasing, despite scant evidence that it improves outcomes. Little is known about the knowledge, perspectives, and clinical characteristics of surgeons associated with MRI use. METHODS: Women with early-stage breast cancer undergoing definitive surgery between July 2013 and August 2015 were identified from the Los Angeles and Georgia Surveillance, Epidemiology and End Results (SEER) registries and were asked to name their attending surgeons...
March 22, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28319436/estimating-the-risks-of-breast-cancer-radiotherapy-evidence-from-modern-radiation-doses-to-the-lungs-and-heart-and-from-previous-randomized-trials
#2
Carolyn Taylor, Candace Correa, Frances K Duane, Marianne C Aznar, Stewart J Anderson, Jonas Bergh, David Dodwell, Marianne Ewertz, Richard Gray, Reshma Jagsi, Lori Pierce, Kathleen I Pritchard, Sandra Swain, Zhe Wang, Yaochen Wang, Tim Whelan, Richard Peto, Paul McGale
Purpose Radiotherapy reduces the absolute risk of breast cancer mortality by a few percentage points in suitable women but can cause a second cancer or heart disease decades later. We estimated the absolute long-term risks of modern breast cancer radiotherapy. Methods First, a systematic literature review was performed of lung and heart doses in breast cancer regimens published during 2010 to 2015. Second, individual patient data meta-analyses of 40,781 women randomly assigned to breast cancer radiotherapy versus no radiotherapy in 75 trials yielded rate ratios (RRs) for second primary cancers and cause-specific mortality and excess RRs (ERRs) per Gy for incident lung cancer and cardiac mortality...
March 20, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28304083/influence-of-human-papillomavirus-on-the-clinical-presentation-of-oropharyngeal-carcinoma-in-the-united-states
#3
Matthew H Stenmark, Dean Shumway, Cui Guo, Jeffrey Vainshtein, Michelle Mierzwa, Reshma Jagsi, Jennifer J Griggs, Mousumi Banerjee
OBJECTIVE: Much of what is known about the significance of human papillomavirus (HPV) in oropharyngeal squamous cell carcinoma is derived from single-institution retrospective studies, post hoc analyses of tissue specimens from clinical trials, and tissue bank studies with a small sample size. The objective of this study is to investigate the impact of HPV on the frequency and clinical presentation of oropharyngeal carcinoma in a large, national sample with information from patients who underwent HPV testing...
March 17, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28241219/differences-in-mentor-mentee-sponsorship-in-male-vs-female-recipients-of-national-institutes-of-health-grants
#4
Elizabeth W Patton, Kent A Griffith, Rochelle D Jones, Abigail Stewart, Peter A Ubel, Reshma Jagsi
No abstract text is available yet for this article.
February 20, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28198770/should-immediate-autologous-breast-reconstruction-be-considered-in-women-who-require-post-mastectomy-radiation-therapy-a-prospective-analysis-of-outcomes
#5
Jessica Billig, Reshma Jagsi, Ji Qi, Jennifer B Hamill, Hyungjin M Kim, Andrea L Pusic, Edward Buchel, Edwin G Wilkins, Adeyiza O Momoh
BACKGROUND: In women who require post-mastectomy radiation therapy, immediate autologous breast reconstruction is often discouraged. We aim to prospectively evaluate postoperative morbidity and satisfaction reported by women undergoing delayed or immediate autologous breast reconstruction in the setting of post-mastectomy radiation therapy. METHODS: Patients enrolled in the Mastectomy Reconstruction Outcomes Consortium Study, who received post-mastectomy radiotherapy and had immediate or delayed free abdominal-based autologous breast reconstruction were identified...
February 13, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28196607/development-of-a-model-web-based-system-to-support-a-statewide-quality-consortium-in-radiation-oncology
#6
Jean M Moran, Mary Feng, Lisa A Benedetti, Robin Marsh, Kent A Griffith, Martha M Matuszak, Michael Hess, Matthew McMullen, Jennifer H Fisher, Teamour Nurushev, Margaret Grubb, Stephen Gardner, Daniel Nielsen, Reshma Jagsi, James A Hayman, Lori J Pierce
PURPOSE: A database in which patient data are compiled allows analytic opportunities for continuous improvements in treatment quality and comparative effectiveness research. We describe the development of a novel, web-based system that supports the collection of complex radiation treatment planning information from centers that use diverse techniques, software, and hardware for radiation oncology care in a statewide quality collaborative, the Michigan Radiation Oncology Quality Consortium (MROQC)...
October 20, 2016: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28170472/genetic-testing-and-counseling-among-patients-with-newly-diagnosed-breast-cancer
#7
LETTER
Allison W Kurian, Kent A Griffith, Ann S Hamilton, Kevin C Ward, Monica Morrow, Steven J Katz, Reshma Jagsi
No abstract text is available yet for this article.
February 7, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28158322/from-muslim-registries-to-radical-health-care-reform-caring-for-patients-in-an-era-of-political-anxiety
#8
Reshma Jagsi
No abstract text is available yet for this article.
March 1, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28152870/recurrence-risk-perception-and-quality-of-life-after-treatment-of-breast-cancer
#9
Nancy K Janz, Reshma Jagsi, Kent A Griffith, Christopher Ryan Friese, Allison W Kurian, Monica Morrow, Lauren P Wallner, Steven J Katz
175 Background: Many breast cancer patients overestimate their risk of distant recurrence after treatment. We explored risk perception in a large, diverse population of breast cancer patients with favorable prognosis and assessed associations between overestimation and quality of life (QoL). METHODS: As part of the iCanCare Study, we surveyed a weighted random sample of newly diagnosed patients with early-stage breast cancer treated in 2013-14, identified through the population-based SEER registries of Los Angeles & Georgia about 3 months after surgical treatment (N = 2632, RR = 70%)...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28152829/prevalence-and-predictors-of-second-opinions-from-medical-oncologists-for-early-stage-breast-cancer-results-from-the-icancare-study
#10
Christopher Ryan Friese, Irina Bondarenko, Reshma Jagsi, Steven J Katz
185 Background: A second medical oncology opinion (SMO) may facilitate chemotherapy decision-making. However, little is known about the interplay between SMOs, treatment decision-making and chemotherapy use. METHODS: We surveyed women newly diagnosed with early-stage invasive breast cancer and treated in 2013-2014 (response rate 70%), accrued approximately 3 months after surgery through 2 population-based SEER registries (Georgia and Los Angeles), about their experiences with medical oncologists, decision-making, and chemotherapy use...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28118107/patient-perspectives-on-the-ethical-implementation-of-a-rapid-learning-system-for-oncology-care
#11
Rochelle D Jones, Aaron N Sabolch, Erin Aakhus, Rebecca A Spence, Angela R Bradbury, Reshma Jagsi
INTRODUCTION: A rapid learning system (RLS) of health care harnesses data generated from routine patient care to create a virtuous cycle of data collection and analysis for quality improvement and research. The success of such systems depends on understanding patient perspectives regarding the ethical issues that arise from the ongoing implementation of this transformative concept. METHODS: An interview guide was designed to evaluate patient perspectives to inform the ethical implementation of an oncology RLS...
March 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28118106/qualitative-study-of-oncologists-views-on-the-cancerlinq-rapid-learning-system
#12
Rachel M Mayo, Julie F Summey, Joel E Williams, Rebecca A Spence, Shally Kim, Reshma Jagsi
INTRODUCTION: ASCO is actively developing CancerLinQ (CLQ), a rapid learning system for oncology care. The purpose of this study was to explore providers' opinions and concerns related to implementation of CLQ, including ethical issues. METHODS: Twenty key informant oncologists were recruited for individual in-depth interviews through ASCO contacts, purposively selected to represent a wide variety of cancer specialties as well as different levels of familiarity with CLQ (familiar v unfamiliar)...
March 2017: Journal of Oncology Practice
https://www.readbyqxmd.com/read/28117882/treatment-associated-toxicities-reported-by-patients-with-early-stage-invasive-breast-cancer
#13
Christopher R Friese, Jordan M Harrison, Nancy K Janz, Reshma Jagsi, Monica Morrow, Yun Li, Ann S Hamilton, Kevin C Ward, Allison W Kurian, Steven J Katz, Timothy P Hofer
BACKGROUND: Patient-reported toxicities help to appraise the breast cancer treatment experience. Yet extant data come from clinical trials and health care claims, which may be biased. Using patient surveys, the authors sought to quantify the frequency, severity, and burden of treatment-associated toxicities. METHODS: Between 2013 and 2014, the iCanCare study surveyed a population-based sample of women residing in Los Angeles County and Georgia with early-stage, invasive breast cancer...
January 24, 2017: Cancer
https://www.readbyqxmd.com/read/28033448/second-opinions-from-medical-oncologists-for-early-stage-breast-cancer-prevalence-correlates-and-consequences
#14
Allison W Kurian, Christopher R Friese, Irina Bondarenko, Reshma Jagsi, Yun Li, Ann S Hamilton, Kevin C Ward, Steven J Katz
Importance: Advances in the evaluation and treatment of breast cancer have made the clinical decision-making context much more complex. A second opinion from a medical oncologist may facilitate decision making for women with breast cancer, yet little is known about second opinion use. Objective: To investigate the patterns and correlates of second opinion use and the effect on chemotherapy decisions. Design, Setting, and Participants: A total of 1901 women newly diagnosed with stages 0 to II breast cancer between July 2013 and September 2014 (response rate, 71...
March 1, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28033439/a-standard-set-of-value-based-patient-centered-outcomes-for-breast-cancer-the-international-consortium-for-health-outcomes-measurement-ichom-initiative
#15
Wee Loon Ong, Maartje G Schouwenburg, Annelotte C M van Bommel, Caleb Stowell, Kim H Allison, Karen E Benn, John P Browne, Rodney D Cooter, Geoff P Delaney, Francois P Duhoux, Patricia A Ganz, Patricia Hancock, Reshma Jagsi, Felicia M Knaul, Anne M Knip, Linetta B Koppert, Henry M Kuerer, Sarah McLaughin, Marc A M Mureau, Ann H Partridge, Dereesa Purtell Reid, Lisa Sheeran, Thomas J Smith, Mark J Stoutjesdijk, Marie Jeanne T F D Vrancken Peeters, Yvonne Wengström, Cheng-Har Yip, Christobel Saunders
A major challenge in value-based health care is the lack of standardized health outcomes measurements, hindering optimal monitoring and comparison of the quality of health care across different settings globally. The International Consortium for Health Outcomes Measurement (ICHOM) assembled a multidisciplinary international working group, comprised of 26 health care providers and patient advocates, to develop a standard set of value-based patient-centered outcomes for breast cancer (BC). The working group convened via 8 teleconferences and completed a follow-up survey after each meeting...
December 29, 2016: JAMA Oncology
https://www.readbyqxmd.com/read/28012085/the-influence-of-21-gene-recurrence-score-assay-on-chemotherapy-use-in-a-population-based-sample-of-breast-cancer-patients
#16
Yun Li, Allison W Kurian, Irina Bondarenko, Jeremy M G Taylor, Reshma Jagsi, Kevin C Ward, Ann S Hamilton, Steven J Katz, Timothy P Hofer
PURPOSE: To quantify the influence of RS assay on changing chemotherapy plans in a general practice setting using causal inference methods. METHODS: We surveyed 3880 newly diagnosed breast cancer patients in Los Angeles and Georgia in 2013-14. We used inverse propensity weighting and multiple imputations to derive complete information for each patient about treatment status with and without testing. RESULTS: A half of the 1545 women eligible for testing (ER+ or PR+, HER2-, and stage I-II) received RS...
February 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28011046/promoting-the-appropriate-use-of-advanced-radiation-technologies-in-oncology-summary-of-a-national-cancer-policy-forum-workshop
#17
Grace L Smith, Patricia A Ganz, Justin E Bekelman, Steven J Chmura, James J Dignam, Jason A Efstathiou, Reshma Jagsi, Peter A Johnstone, Michael L Steinberg, Stephen B Williams, James B Yu, Anthony L Zietman, Ralph R Weichselbaum, Ya-Chen Tina Shih
PURPOSE: Leaders in the oncology community are sounding a clarion call to promote "value" in cancer care decisions. Value in cancer care considers the clinical effectiveness, along with the costs, when selecting a treatment. To discuss possible solutions to the current obstacles to achieving value in the use of advanced technologies in oncology, the National Cancer Policy Forum of the National Academies of Sciences, Engineering, and Medicine held a workshop, "Appropriate Use of Advanced Technologies for Radiation Therapy and Surgery in Oncology" in July 2015...
March 1, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/28004220/recurrence-risk-perception-and-quality-of-life-following-treatment-of-breast-cancer
#18
Sarah T Hawley, Nancy K Janz, Kent A Griffith, Reshma Jagsi, Christopher R Friese, Allison W Kurian, Ann S Hamilton, Kevin C Ward, Monica Morrow, Lauren P Wallner, Steven J Katz
PURPOSE: Little is known about different ways of assessing risk of distant recurrence following cancer treatment (e.g., numeric or descriptive). We sought to evaluate the association between overestimation of risk of distant recurrence of breast cancer and key patient-reported outcomes, including quality of life and worry. METHODS: We surveyed a weighted random sample of newly diagnosed patients with early-stage breast cancer identified through SEER registries of Los Angeles County & Georgia (2013-14) ~2 months after surgery (N = 2578, RR = 71%)...
February 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28002555/contralateral-prophylactic-mastectomy-decisions-in-a-population-based-sample-of-patients-with-early-stage-breast-cancer
#19
Reshma Jagsi, Sarah T Hawley, Kent A Griffith, Nancy K Janz, Allison W Kurian, Kevin C Ward, Ann S Hamilton, Monica Morrow, Steven J Katz
Importance: Contralateral prophylactic mastectomy (CPM) use is increasing among women with unilateral breast cancer, but little is known about treatment decision making or physician interactions in diverse patient populations. Objective: To evaluate patient motivations, knowledge, and decisions, as well as the impact of surgeon recommendations, in a large, diverse sample of patients who underwent recent treatment for breast cancer. Design, Setting, and Participants: A survey was sent to 3631 women with newly diagnosed, unilateral stage 0, I, or II breast cancer between July 2013 and September 2014...
March 1, 2017: JAMA Surgery
https://www.readbyqxmd.com/read/27986344/decreased-lung-perfusion-after-breast-chest-wall-irradiation-quantitative-results-from-a-prospective-clinical-trial
#20
Adam L Liss, Robin B Marsh, Nirav S Kapadia, Daniel L McShan, Virginia E Rogers, James M Balter, Jean M Moran, Kristy K Brock, Matt J Schipper, Reshma Jagsi, Kent A Griffith, Kevin R Flaherty, Kirk A Frey, Lori J Pierce
PURPOSE: To quantify lung perfusion changes after breast/chest wall radiation therapy (RT) using pre- and post-RT single photon emission computed tomography/computed tomography (SPECT/CT) attenuation-corrected perfusion scans; and correlate decreased perfusion with adjuvant RT dose for breast cancer in a prospective clinical trial. METHODS AND MATERIALS: As part of an institutional review board-approved trial studying the impact of RT technique on lung function in node-positive breast cancer, patients received breast/chest wall and regional nodal irradiation including superior internal mammary node RT to 50 to 52...
February 1, 2017: International Journal of Radiation Oncology, Biology, Physics
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