keyword
MENU ▼
Read by QxMD icon Read
search

Pharmaceutical Science

keyword
https://www.readbyqxmd.com/read/27934549/burden-of-illness-and-research-investments-in-translational-sciences-for-pharmaceuticals-in-metastatic-cancers
#1
Wei-Jhih Wang, Justin C Robertson, Anirban Basu
AIM: To explore whether investments in translational sciences for six metastatic cancers follow idiosyncratic returns to those investments rather than levels of burden of illness (BI). METHODS: Associate the number of translational clinical trials in the USA involving oncolytic drugs approved during 2008-2013 and the level (in 2008) and changes (2002-2008 and 2008-2014) in cancer-specific years of life lost. RESULTS: Investments in trials were positively associated only with contemporary changes in BI (2008-2014)...
December 9, 2016: Journal of Comparative Effectiveness Research
https://www.readbyqxmd.com/read/27931386/fate-of-environmental-pollutants
#2
Lokesh P Padhye
This annual review covers the literature published in 2015 on topics related to the occurrence and fate of emerging environmental pollutants in wastewater. Due to the vast amount of literature published on this topic, I have discussed only a fraction of the quality research publications, up to maximum 20 relevant articles per section, due to limitation of space. The abstract search was carried out using Web of Science, and the abstracts were selected based on their relevance. In few cases, full-text articles were referred to better understand new findings...
October 2016: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/27928960/research-advances-in-molecular-modeling-in-cyclodextrins
#3
Qianqian Zhao, Weixiang Zhang, Runmiao Wang, Yitao Wang, Defang Ouyang
BACKGROUND: Cyclodextrins (CDs), as one type of the novel pharmaceutical excipients, have been widely used in drug delivery and pharmaceutical industry. Over the past decades, a large amount of molecular modeling studies in CDs were reported for profound understanding of structural, dynamic and energetic features of CDs systems. Thus, this review is focused on qualitative and quantitative analysis of research outputs on molecular modeling in CDs. METHODS: The original data were collected from Web of Science and analyzed by scientific knowledge mapping tools, including Citespace, Science of Science, VOSviewer, GPSvisualizer and Gephi software...
December 8, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27928543/bayesian-statistical-methods-and-their-valuable-applications-in-the-pharmaceutical-sciences
#4
Farzan Madadizadeh, Mohammad Ezati Asar, Mostafa Hosseini
No abstract text is available yet for this article.
August 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27928524/review-of-medicinal-remedies-on-hand-eczema-based-on-iranian-traditional-medicine-a-narrative-review-article
#5
REVIEW
Parvin Mansouri, Aleme Khademi, Daryoush Pahlevan, Zahra Memariani, Jale Aliasl, Laila Shirbeigii
BACKGROUND: Hand Eczema (HE) is a dermatological disorder with frequent relapses and multiple causes such as atopic, allergic and irritant contact dermatitis. The management is complex because of the wide range of different pathogenesis. Efficacy of some of available treatments is not well established and it can affect patients' quality of life significantly. METHODS: Reports on HE such as diagnosis, pathophysiology, pharmacological and nonpharmacological therapy that described in medieval Iranian medicine, were gathered and analyzed from selected medical and pharmaceutical textbooks of Iranian Traditional Medicine (ITM)...
August 2016: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/27920947/the-daniel-k-inouye-college-of-pharmacy-scripts-poha-berry-physalis-peruviana-with-potential-anti-inflammatory-and-cancer-prevention-activities
#6
Leng Chee Chang, Mayuramas Sang-Ngern, John M Pezzuto, Carolyn Ma
The Daniel K. Inouye College of Pharmacy, during a historic event in Spring 2016, graduated the first two students in the Pacific region to earn a PhD in pharmaceutical sciences at the University of Hawai'i at Hilo. The college offers PhD programs in these five disciplines: Cancer Biology, Medicinal Chemistry, Pharmaceutics, Pharmacognosy, and Pharmacology. One of the Pharmacognosy dissertations focused on plant-derived natural products with potential anti-inflammatory and cancer chemopreventive activities...
November 2016: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
https://www.readbyqxmd.com/read/27920427/mixing-of-quantum-states-a-new-route-to-creating-optical-activity
#7
Anvar S Baimuratov, Nikita V Tepliakov, Yurii K Gun'ko, Alexander V Baranov, Anatoly V Fedorov, Ivan D Rukhlenko
The ability to induce optical activity in nanoparticles and dynamically control its strength is of great practical importance due to potential applications in various areas, including biochemistry, toxicology, and pharmaceutical science. Here we propose a new method of creating optical activity in originally achiral quantum nanostructures based on the mixing of their energy states of different parities. The mixing can be achieved by selective excitation of specific states or via perturbing all the states in a controllable fashion...
December 2016: Scientific Reports
https://www.readbyqxmd.com/read/27918088/cerebrolysin-for-acute-ischaemic-stroke
#8
REVIEW
Liliya Eugenevna Ziganshina, Tatyana Abakumova, Ludivine Vernay
BACKGROUND: Cerebrolysin is a mixture of low-molecular-weight peptides and amino acids derived from pigs' brain tissue, which has potential neuroprotective and neurotrophic properties. It is widely used in the treatment of acute ischaemic stroke in Russia, Eastern Europe, China, and other Asian and post-Soviet countries. OBJECTIVES: To assess the benefits and risks of cerebrolysin for treating acute ischaemic stroke. SEARCH METHODS: In May 2016 we searched the Cochrane Stroke Group Trials Register, CENTRAL, MEDLINE, Embase, Web of Science Core Collection, with Science Citation Index, LILACS, OpenGrey, and a number of Russian Databases...
December 5, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27915982/molecular-cellular-and-pharmaceutical-aspects-of-bone-grafting-materials-and-membranes-during-maxillary-sinus-lift-procedures-part-2-detailed-characteristics-of-the-materials
#9
Giovanna Iezzi, Adriano Piatelli, Alessandra Giuliani, Carlo Mangano, Antonio Barone, Licia Manzon, Marco Degidi, Antonio Scarano, Antonella Filippone, Vittoria Perrotti
Various grafts or combination of bone substitute materials have been used in sinus lift procedures. Currently, ongoing developments in several disciplines, from molecular biology and chemistry to computer science and engineering, have contributed to the understanding of biological processes leading to bone healing after the use of bone substitute materials (BSBs) and therefore of the behavior of BSBs. The understanding of the properties of each graft enables individual treatment concepts and therefore allows shift from a simple replacement material to the modern concept of an individually created composite biomaterial...
December 1, 2016: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/27915194/quantitative-determination-of-salbutamol-sulfate-impurities-using-achiral-supercritical-fluid-chromatography
#10
Amandine Dispas, Vincent Desfontaine, Bertyl Andri, Pierre Lebrun, Dorina Kotoni, Adrian Clarke, Davy Guillarme, Philippe Hubert
In the last years, supercritical fluid chromatography has largely been acknowledged as a singular and performing technique in the field of separation sciences. Recent studies highlighted the interest of SFC for the quality control of pharmaceuticals, especially in the case of the determination of the active pharmaceutical ingredient (API). Nevertheless, quality control requires also the determination of impurities. The objectives of the present work were to (i) demonstrate the interest of SFC as a reference technique for the determination of impurities in salbutamol sulfate API and (ii) to propose an alternative to a reference HPLC method from the European Pharmacopeia (EP) involving ion-pairing reagent...
November 27, 2016: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/27907110/electrospray-ionization-efficiency-is-dependent-on-different-molecular-descriptors-with-respect-to-solvent-ph-and-instrumental-configuration
#11
Andreas Kiontke, Ariana Oliveira-Birkmeier, Andreas Opitz, Claudia Birkemeyer
Over the past decades, electrospray ionization for mass spectrometry (ESI-MS) has become one of the most commonly employed techniques in analytical chemistry, mainly due to its broad applicability to polar and semipolar compounds and the superior selectivity which is achieved in combination with high resolution separation techniques. However, responsiveness of an analytical method also determines its suitability for the quantitation of chemical compounds; and in electrospray ionization for mass spectrometry, it can vary significantly among different analytes with identical solution concentrations...
2016: PloS One
https://www.readbyqxmd.com/read/27904099/effects-of-reinforcement-method-of-dissection-physiology-education-on-the-achievement-in-pharmacology
#12
Tomoya Kitayama, Satomi Kagota, Noriko Yoshikawa, Nobuyuki Kawai, Kanae Nishimura, Takeshi Miura, Naomi Yasui, Kazumasa Shinozuka, Toshikatsu Nakabayashi
 The Pharmaceutical Education Support Center was established in the Department of Pharmacy at the School of Pharmacy and Pharmaceutical Science of Mukogawa Women's University in 2014. We started teaching first and second years students according to proficiency from the 2014 academic year. Students were divided into two classes: the regular class (high proficiency class) and the basic class (low proficiency class), based on achievement in several basic subjects related to the study of pharmacy. The staffs in the Pharmaceutical Education Support Center reinforce what is taught to students in the basic class...
2016: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/27900421/spectroscopic-sensors-for-in-line-bioprocess-monitoring-in-research-and-pharmaceutical-industrial-application
#13
REVIEW
Jens Claßen, Florian Aupert, Kenneth F Reardon, Dörte Solle, Thomas Scheper
The use of spectroscopic sensors for bioprocess monitoring is a powerful tool within the process analytical technology (PAT) initiative of the US Food and Drug Administration. Spectroscopic sensors enable the simultaneous real-time bioprocess monitoring of various critical process parameters including biological, chemical, and physical variables during the entire biotechnological production process. This potential can be realized through the combination of spectroscopic measurements (UV/Vis spectroscopy, IR spectroscopy, fluorescence spectroscopy, and Raman spectroscopy) with multivariate data analysis to obtain relevant process information out of an enormous amount of data...
November 30, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27896684/use-of-spray-dried-dispersions-in-early-pharmaceutical-development-theoretical-and-practical-challenges
#14
Jinjiang Li, Dhaval Patel, George Wang
Spray-dried dispersions (SDDs) have become an important formulation technology for the pharmaceutical product development of poorly water-soluble (PWS) compounds. Although this technology is now widely used in the industry, especially in the early-phase development, the lack of mechanistic understanding still causes difficulty in selecting excipients and predicting stability of SDD-based drug products. In this review, the authors aim to discuss several principles of polymer science pertaining to the development of SDDs, in terms of selecting polymers and solvents, optimizing drug loading, as well as assessing physical stability on storage and supersaturation maintenance after dissolution, from both thermodynamic and kinetic considerations...
November 28, 2016: AAPS Journal
https://www.readbyqxmd.com/read/27890023/progressive-muscle-relaxation-as-a-supportive-intervention-for-cancer-patients-undergoing-chemotherapy-a-systematic-review
#15
Panagiotis Pelekasis, Ifigeneia Matsouka, Anna Koumarianou
BACKGROUND: Many cancer patients use a wide variety of techniques to improve their physical and mental well-being, including relaxation therapy and, specifically, Progressive Muscle Relaxation (PMR). However, there is no strong evidence that supports the efficacy of this technique. OBJECTIVE: Our aim was to review the evidence regarding the use of PMR as a supportive intervention for cancer patients undergoing chemotherapeutic treatment. METHOD: Six databases were electronically searched: AMED, the Cochrane Library, MEDLINE, PsychINFO, Scopus, and the Web of Science...
November 28, 2016: Palliative & Supportive Care
https://www.readbyqxmd.com/read/27889353/review-on-fate-and-mechanism-of-removal-of-pharmaceutical-pollutants-from-wastewater-using-biological-approach
#16
REVIEW
Bhagyashree Tiwari, Balasubramanian Sellamuthu, Yassine Ouarda, Patrick Drogui, Rajeshwar D Tyagi, Gerardo Buelna
Due to research advancement and discoveries in the field of medical science, maintains and provides better human health and safer life, which lead to high demand for production of pharmaceutical compounds with a concomitant increase in population. These pharmaceutical (biologically active) compounds were not fully metabolized by the body and excreted out in wastewater. This micro-pollutant remains unchanged during wastewater treatment plant operation and enters into the receiving environment via the discharge of treated water...
November 15, 2016: Bioresource Technology
https://www.readbyqxmd.com/read/27885934/the-path-to-producing-pharmaceuticals-from-natural-products-uncovered-by-academia-from-the-perspective-of-a-science-coordinator
#17
Akihiko Fujie
To actualize the invention of all-Japanese medicines, the Department of Innovative Drug Discovery and Development (iD3) in the Japan Agency for Medical Research and Development (AMED) serves as the headquarters for the Drug Discovery Support Network. iD3 assists with creating research strategies for the seeds of medicines discovered by academia and provides technological support, intellectual property management, and aid for applying the seeds through industry-led efforts. In this review, from the perspective of a science coordinator, I will describe the current activities of the drug discovery support network and iD3 as well as the challenges and future developments of pharmaceutical research and development using the natural product drug discovery method...
January 2017: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/27881189/pharmaceutical-patenting-and-the-transformation-of-american-medical-ethics
#18
Joseph M Gabriel
The attitudes of physicians and drug manufacturers in the US toward patenting pharmaceuticals changed dramatically from the mid-nineteenth century to the mid-twentieth. Formerly, physicians and reputable manufacturers argued that pharmaceutical patents prioritized profit over the advancement of medical science. Reputable manufactures refused to patent their goods and most physicians shunned patented products. However, moving into the early twentieth century, physicians and drug manufacturers grew increasingly comfortable with the idea of pharmaceutical patents...
November 24, 2016: British Journal for the History of Science
https://www.readbyqxmd.com/read/27876365/midyear-commentary-on-trends-in-drug-delivery-and-clinical-translational-medicine-growth-in-biosimilar-complex-injectable-drug-formulation-products-within-evolving-collaborative-regulatory-interagency-fda-ftc-and-doj-practices-and-enforcement
#19
Rodney J Y Ho
Before the 2009 Biologics Price Competition and Innovation Act that enabled the U.S. Federal Drug Administration (FDA) to create the 351(k) Biologic License Application-an abbreviated biosimilar approval process, FDA approved follow-on biomolecule products such as beta-interferon, glucagon, hyaluronidase, and somatropin (human growth hormone) under varying and evolving rules. With the 351(k) Biologic License Application biosimilar approval process in place, currently, there are 4 (licensed in 2015-2016) biosimilars available, namely Neupogen (filgrastim; $1 B/y), Humira (adalumumab; $14...
November 19, 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27866605/hydrothermal-preparation-of-reduced-graphene-oxide-silver-nanocomposite-using-plectranthus-amboinicus-leaf-extract-and-its-electrochemical-performance
#20
Yuhong Zheng, Aiwu Wang, Wen Cai, Zhong Wang, Feng Peng, Zhong Liu, Li Fu
Graphene based nanocomposites are receiving increasing attention in many fields such as material chemistry, environmental science and pharmaceutical science. In this study, a facial synthesis of a reduced graphene oxide-silver nanocomposite (RGO-Ag) was carried out from Plectranthus amboinicus leaf extract. The synthesized nanocomposite was characterized by using X-ray diffraction, scanning electron microscope, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, transmission electron microscope and UV-vis spectroscopy for structural confirmation...
December 2016: Enzyme and Microbial Technology
keyword
keyword
2758
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"