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Swallowing physiology

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https://www.readbyqxmd.com/read/29123186/the-biomechanical-coordination-during-oropharyngeal-swallowing-an-evaluation-with-a-non-invasive-sensing-system
#1
Qiang Li, Yoshitomo Minagi, Takahiro Ono, Yongjin Chen, Kazuhiro Hori, Shigehiro Fujiwara, Yoshinobu Maeda
Swallowing is a very important and complex physiological behaviour. The dynamic of swallowing has created great interest as any procedural abnormality will result in dysphagia and even lower quality of life. However, a non-invasive evaluation of biomechanical coordination during oropharyngeal swallowing, which includes the activities of the tongue, the hyoid and swallowing-related muscles, has not yet been achieved. In the present study, we recruited fifteen subjects, and a non-invasive sensing system composed of a pressure sensor, a bend sensor, surface electrodes and a microphone was created to simultaneously monitor tongue pressure, hyoid motion, and surface EMG of swallowing-related muscles, as well as take sound recordings, when the subjects swallowed 5 ml of water...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29103061/the-use-of-surface-electromyography-in-dysphagia-evaluation
#2
Yao-Chin Wang, Willy Chou, Bor-Shing Lin, Jhi-Joung Wang, Bor-Shyh Lin
Dysphagic patients usually have a variety of clinical problems such as malnutrition, significant weight loss, and aspiration pneumonia. Dysphagia is a complication commonly caused by strokes, and surface electromyography (sEMG) provides a simple, non-radioactive, and non-invasive method to measure the patterns of muscle activity during swallowing, allowing clinicians to describe the physiology of swallowing behavior. Most previous studies have described swallowing behavior in terms of amplitude and duration...
October 23, 2017: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29071968/-clinical-trials-for-treatment-of-stroke-patients-with-dysphagia-by-vitalstim-electroacupuncture-combined-with-swallowing-rehabilitation-training
#3
Sheng-Yu Zhang, Shao-Bing Liu, Wei Wu, Yi-Min Chen, Kang-Lin Liao, Yong Xiang, Dun Pan
OBJECTIVE: To observe the clinical effect of vitalstim electroacupuncture (EA) combined with swallowing rehabilitation training in the treatment of stroke patients with dysphagia. METHODS: A total of 80 stroke patients with dysphagia were randomized into treatment and control groups (n=40 in each group). Patients of the control group were treated by regular medication for anti-platelet aggregation and anti-coagulation, lipid-lowering, neuroprotection, blood glucose control and blood pressure control, etc...
April 25, 2017: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29069620/propofol-protects-rat-hypoglossal-motoneurons-in-an-in-vitro-model-of-excitotoxicity-by-boosting-gabaergic-inhibition-and-reducing-oxidative-stress
#4
Filippo Ghezzi, Laura Monni, Silvia Corsini, Rossana Rauti, Andrea Nistri
In brainstem motor networks, hypoglossal motoneurons (HMs) play the physiological role of driving tongue contraction, an activity critical for inspiration, phonation, chewing and swallowing. HMs are an early target of neurodegenerative diseases like amyotrophic lateral sclerosis that, in its bulbar form, is manifested with initial dysphagia and dysarthria. One important pathogenetic component of this disease is the high level of extracellular glutamate due to uptake block that generates excitotoxicity. To understand the earliest phases of this condition we devised a model, the rat brainstem slice, in which block of glutamate uptake is associated with intense bursting of HMs, dysmetabolism and death...
October 22, 2017: Neuroscience
https://www.readbyqxmd.com/read/29063658/physiological-augmentation-of-esophageal-distension-pressure-and-peristalsis-during-conditions-of-increased-esophageal-emptying-resistance
#5
G J Brink, W Y Lei, T I Omari, M M J Singendonk, J S Hung, T T Liu, C H Yi, C L Chen
BACKGROUND: Abdominal compression has been implemented as a provocative maneuver in high-resolution impedance manometry (HRIM) to "challenge" normal esophageal physiology with the aim of revealing abnormal motor patterns which may explain symptoms. In this study, we measured the effects of abdominal compression on esophageal functioning utilizing novel pressure-impedance parameters and attempted to identify differences between healthy controls and globus patients. METHODS: Twenty-two healthy volunteers (aged 23-32 years, 41% female) and 22 globus patients (aged 23-72 years, 68% female) were evaluated with HRIM using a 3...
October 24, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29054835/a-strategy-to-reduce-critical-cardiorespiratory-alarms-due-to-intermittent-enteral-feeding-of-preterm-neonates-in-intensive-care
#6
Rohan Joshi, Carola van Pul, Anouk Sanders, Hans Weda, Jan Willem Bikker, Loe Feijs, Peter Andriessen
BACKGROUND: Many preterm infants require enteral feeding as they cannot coordinate sucking, swallowing, and breathing. In enteral feeding, milk feeds are delivered through a small feeding tube passed via the nose or mouth into the stomach. Intermittent milk feeds may either be administered using a syringe to gently push milk into the infant's stomach (push feed) or milk can be poured into a syringe attached to the tube and allowed to drip in by gravity (gravity feed). This practice of enteral feeding is common in neonatal intensive care units...
October 20, 2017: Interactive Journal of Medical Research
https://www.readbyqxmd.com/read/29043407/changes-in-swallowing-symptoms-and-esophageal-motility-after-thyroid-surgery-a-prospective-cohort-study
#7
Jesper Roed Sorensen, Simone Markoew, Helle Døssing, Laszlo Hegedüs, Steen Joop Bonnema, Christian Godballe
INTRODUCTION: Swallowing difficulties, the pathophysiology behind which is incompletely understood, have been reported in 47-83% of goiter patients referred for thyroidectomy. We aimed at examining the influence of thyroid surgery on swallowing symptoms and esophageal motility. METHODS: Thirty-three patients with benign nodular goiter undergoing thyroid surgery were included. All completed high-resolution esophageal manometry examinations and the goiter symptom scale score, assessed by the thyroid-specific patient-reported outcome measure...
October 11, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29041932/stamps-development-and-verification-of-swallowing-kinematic-analysis-software
#8
Woo Hyung Lee, Changmook Chun, Han Gil Seo, Seung Hak Lee, Byung-Mo Oh
BACKGROUND: Swallowing impairment is a common complication in various geriatric and neurodegenerative diseases. Swallowing kinematic analysis is essential to quantitatively evaluate the swallowing motion of the oropharyngeal structures. This study aims to develop a novel swallowing kinematic analysis software, called spatio-temporal analyzer for motion and physiologic study (STAMPS), and verify its validity and reliability. METHODS: STAMPS was developed in MATLAB, which is one of the most popular platforms for biomedical analysis...
October 17, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29041008/increase-of-substance-p-concentration-in-saliva-after-pharyngeal-electrical-stimulation-in-severely-dysphagic-stroke-patients-an-indicator-of-decannulation-success
#9
Paul Muhle, Sonja Suntrup-Krueger, Stefan Bittner, Tobias Ruck, Inga Claus, Thomas Marian, Jens B Schröder, Jens Minnerup, Tobias Warnecke, Sven G Meuth, Rainer Dziewas
BACKGROUND/AIMS: Substance P (SP) is a neuropeptide, likely acting as a neurotransmitter in the pharyngeal mucosa enhancing the swallow and cough reflex. Pharyngeal Electrical Stimulation (PES) induces a temporary increase of salivary SP levels in healthy adults. Previous evidence suggests that post-stroke dysphagia is related to reduced SP levels. Here, we investigated the effects of PES on SP levels in severely dysphagic stroke patients and a possible link between increase of SP and treatment success...
October 17, 2017: Neuro-Signals
https://www.readbyqxmd.com/read/29026386/effect-of-posture-on-swallowing
#10
Ahmad H Alghadir, Hamayun Zafar, Einas S Al-Eisa, Zaheen A Iqbal
BACKGROUND: Swallowing is a systematic process. Any structural, physiological or neurological disturbance in this process may cause dysphagia. Although there are studies that report head/neck movements during mastication, there are fewer studies that show the effect of different head/neck postures on difficulty while swallowing. OBJECTIVES: To observe the effect of different body postures on the self-perceived difficulty while swallowing in normal healthy subjects...
March 2017: African Health Sciences
https://www.readbyqxmd.com/read/29023260/dysphagia-in-mechanically-ventilated-icu-patients-dynamics-a-prospective-observational-trial
#11
Joerg C Schefold, David Berger, Patrick Zürcher, Michael Lensch, Andrea Perren, Stephan M Jakob, Ilkka Parviainen, Jukka Takala
OBJECTIVES: Swallowing disorders may be associated with adverse clinical outcomes in patients following invasive mechanical ventilation. We investigated the incidence of dysphagia, its time course, and association with clinically relevant outcomes in extubated critically ill patients. DESIGN: Prospective observational trial with systematic dysphagia screening and follow-up until 90 days or death. SETTINGS: ICU of a tertiary care academic center...
October 11, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28967219/the-effect-of-aging-on-mastication-and-swallowing-parameters-according-to-the-hardness-change-of-solid-food
#12
Hyoung Su Park, Don-Kyu Kim, Sang Yi Lee, Ki-Hwan Park
As part of the aging process, multiple oral physiologic changes occur and these changes may cause individuals to reduce food intake or switch the types of food texture. Thus, the need to develop food products for the elderly has increased. To evaluate the suitability of the food products for the elderly, the evaluation method should be verified and it is important to identify the parameters of mastication and swallowing. Therefore, the purpose of this study was to compare the differences of mastication and swallowing parameters between the young adults and the elderly depending on the varying hardness of rice food product...
October 2017: Journal of Texture Studies
https://www.readbyqxmd.com/read/28955672/treatment-of-advanced-carcinoma-of-the-larynx-and-hypopharynx-with-laser-followed-by-external-radiotherapy
#13
Lalee Varghese, John Mathew, Subhashini John, Anand Job
INTRODUCTION: Radical laryngeal surgeries for extensive laryngeal and hypopharyngeal tumors often require a permanent tracheostomy, which has an immense impact on the quality of life of patients. A minimally invasive technique such as transoral laser microresection (TLM) followed by radiotherapy can preserve the functions of the voice and swallowing. The aim of this study is to evaluate the role of laser debulking in the treatment of carcinoma of the larynx and hypopharynx, to evaluate the response of the tumor to subsequent radiotherapy, and also to assess the usefulness of laser in avoiding tracheostomy and functional preservation of the voice and swallowing...
September 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28944343/closed-perforation-of-gastric-fundus-and-gastric-outlet-obstruction-caused-by-a-giant-gastric-trichobezoar-a-case-report
#14
Bünyamin Gürbulak, Özgür Seğmen, Taşkın Rakıcı, Kenan Büyükaşık, Mazlum Yavaş
A bezoar is a mass formed because of the accumulation of indigestible material in the stomach and/or small intestine. Bezoars are rare but occasionally occur with acute abdomen findings. Bezoars form as a result of changes in the gastrointestinal system anatomy and physiology and repetitive exposure to the ingested material. These materials can include vegetables with high fiber content (phytobezoars), non-animal origin fats, hair (trichobezoars), or drugs such as anti-acids (pharmobezoars). Gastric bezoars frequently occur after gastric surgery...
2017: Turk J Surg
https://www.readbyqxmd.com/read/28912088/sip-and-spit-or-sip-and-swallow-choice-of-method-differentially-alters-taste-intensity-estimates-across-stimuli
#15
Cordelia A Running, John E Hayes
While the myth of the tongue map has been consistently and repeatedly debunked in controlled studies, evidence for regional differences in suprathreshold intensity has been noted by multiple research groups. Given differences in physiology between the anterior and posterior tongue (fungiform versus foliate and circumvallate papillae) and differences in total area stimulated (anterior only versus whole tongue, pharynx, and epiglottis), small methodological changes (sip and spit versus sip and swallow) have the potential to substantially influence data...
November 1, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28894942/first-steps-towards-development-of-an-instrument-for-the-reproducible-quantification-of-oropharyngeal-swallow-physiology-in-bottle-fed-children
#16
Maureen A Lefton-Greif, Katlyn Elizabeth McGrattan, Kathryn A Carson, Jeanne M Pinto, Jennifer M Wright, Bonnie Martin-Harris
The incidence of feeding/swallowing impairments (deglutition disorders) in young children is rising and poses serious acute and long-term health consequences. Accurate detection and prompt intervention can lessen the impact of dysphagia-induced sequelae. Videofluoroscopic Swallow Studies (VFSSs) are used to make critical decisions for medically fragile children despite procedural variability and the lack of agreed upon measures for interpreting and reporting results. This investigation represents the first steps in the development of a novel tool for the quantification of oropharyngeal swallow physiology from full-length VFSS examinations in bottle-fed children...
September 11, 2017: Dysphagia
https://www.readbyqxmd.com/read/28857171/characterization-of-swallow-modulation-in-response-to-bolus-volume-in-healthy-subjects-accounting-for-catheter-diameter
#17
Lara Ferris, Mistyka Schar, Lisa McCall, Sebastian Doeltgen, Ingrid Scholten, Nathalie Rommel, Charles Cock, Taher Omari
OBJECTIVES/HYPOTHESIS: Characterization of the pharyngeal swallow response to volume challenges is important for swallowing function assessment. The diameter of the pressure-impedance recording catheter may influence these results. In this study, we captured key physiological swallow measures in response to bolus volume utilizing recordings acquired by two catheters of different diameter. STUDY DESIGN: Ten healthy adults underwent repeat investigations with 8- and 10-Fr catheters...
August 31, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28836005/grading-dysphagia-as-a-toxicity-of-head-and-neck-cancer-differences-in-severity-classification-based-on-mbs-digest-and-clinical-ctcae-grades
#18
Ryan P Goepfert, Jan S Lewin, Martha P Barrow, Carla L Warneke, Clifton D Fuller, Stephen Y Lai, Randal S Weber, Katherine A Hutcheson
Clinician-reported toxicity grading through common terminology criteria for adverse events (CTCAE) stages dysphagia based on symptoms, diet, and tube dependence. The new dynamic imaging grade of swallowing toxicity (DIGEST) tool offers a similarly scaled five-point ordinal summary grade of pharyngeal swallowing as determined through results of a modified barium swallow (MBS) study. This study aims to inform clinicians on the similarities and differences between dysphagia severity according to clinical CTCAE and MBS-derived DIGEST grading...
August 23, 2017: Dysphagia
https://www.readbyqxmd.com/read/28831570/differential-response-pattern-of-oropharyngeal-pressure-by-bolus-and-dry-swallows
#19
Mana Hasegawa, Masayuki Kurose, Keiichiro Okamoto, Yoshiaki Yamada, Takanori Tsujimura, Makoto Inoue, Taisuke Sato, Takatsune Narumi, Noritaka Fujii, Kensuke Yamamura
The aim of this study was to determine if bolus and dry swallow showed similar pressure changes in the oropharynx using our newly developed device. A unique character of it includes that baropressure can be measured with the sensor being placed in the balloon and can assess the swallowing mechanics in terms of pressure changes in the oropharynx with less influences of direct contacts of boluses and oropharyngeal structures during swallow indirectly. Fifteen healthy subjects swallowed saliva (dry), 15 ml of water, 45 ml of water, and 15 ml of two different types of food in terms of viscosity (potage soup-type and mayonnaise-type foods)...
August 23, 2017: Dysphagia
https://www.readbyqxmd.com/read/28794695/water-filtered-infrared-a-wira-overcomes-swallowing-disorders-and-hypersalivation-a-case-report
#20
Gerd Hoffmann
Case description: A patient with a Barrett oesophageal carcinoma and a resection of the oesophagus with gastric pull-up developed swallowing disorders 6 years and 2 months after the operation. Within 1 year and 7 months two recurrences of the tumor at the anastomosis were found and treated with combined chemoradiotherapy or chemotherapy respectively. 7 years and 9 months after the operation local tumor masses and destruction were present with no ability to orally drink or eat (full feeding by jejunal PEG tube): quality of life was poor, as saliva and mucus were very viscous (pulling filaments) and could not be swallowed and had to be spat out throughout the day and night resulting in short periods of sleep (awaking from the necessity to spit out)...
2017: German Medical Science: GMS E-journal
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