keyword
https://read.qxmd.com/read/38525756/a-proposal-for-a-multidisciplinary-integrated-oral-health-network-for-patients-undergoing-major-orthopaedic-surgery-iohn-os
#1
JOURNAL ARTICLE
Matteo Briguglio, Thomas W Wainwright, Marialetizia Latella, Aurora Ninfa, Claudio Cordani, Cecilia Colombo, Giuseppe Banfi, Luca Francetti, Stefano Corbella
The passing of the years of life physiologically leads to the accumulation of changes in tissues in the oral cavity, influencing dentition, chewing and swallowing mechanisms, and the oral microbiota. Some diseases and medications can aggravate oral symptoms and negatively influence eating behaviours, increasing the likelihood of becoming malnourished. This could make older individuals more vulnerable to complications when undergoing major orthopaedic surgery. Hidden infection foci in the oral cavity are a recognised cause of post-operative periprosthetic joint infections...
March 19, 2024: Geriatrics
https://read.qxmd.com/read/38523356/the-impact-of-lung-transplantation-on-esophageal-motility-and-inter-relationships-with-reflux-and-lung-mechanics-in-patients-with-restrictive-and-obstructive-respiratory-disease
#2
JOURNAL ARTICLE
Ali Alghubari, Ramsah Cheah, Sadia Z Shah, Abdel-Rahman N Naser, Augustine S Lee, Kenneth R DeVault, Lesley A Houghton
BACKGROUND: For many patients with lung disease the only proven intervention to improve survival and quality of life is lung transplantation (LTx). Esophageal dysmotility and gastroesophageal reflux (GER) are common in patients with respiratory disease, and often associate with worse prognosis following LTx. Which, if any patients, should be excluded from LTx based on esophageal concerns remains unclear. Our aim was to understand the effect of LTx on esophageal motility diagnosis and examine how this and the other physiological and mechanical factors relate to GER and clearance of boluses swallowed...
March 24, 2024: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://read.qxmd.com/read/38521722/pediatric-dysphagia
#3
REVIEW
Wade McClain, Jordan Luttrell, Elton Lambert
Pediatric dysphagia is a common condition encountered in clinical practice. We review the physiology and development of swallow, presentation, epidemiology, and etiology of dysphagia. Additionally, comorbidities, associated conditions, and medical management of dysphagia are discussed.
March 23, 2024: Otolaryngologic Clinics of North America
https://read.qxmd.com/read/38517302/the-neurorehabilitation-of-post-stroke-dysphagia-physiology-and-pathophysiology
#4
JOURNAL ARTICLE
Ayodele Sasegbon, Ivy Cheng, Shaheen Hamdy
Swallowing is a complex process involving the precise contractions of numerous muscles of the head and neck, which act to process and shepherd ingested material from the oral cavity to its eventual destination, the stomach. Over the past five decades, information from animal and human studies has laid bare the complex network of neurones in the brainstem, cortex and cerebellum that are responsible for orchestrating each normal swallow. Amidst this complexity, problems can and often do occur that result in dysphagia, defined as impaired or disordered swallowing...
March 22, 2024: Journal of Physiology
https://read.qxmd.com/read/38516909/pediatric-retrograde-cricopharyngeal-dysfunction-diagnosed-by-high-resolution%C3%A2-impedance-manometry
#5
JOURNAL ARTICLE
Lev Dorfman, Khalil El-Chammas, Sherief Mansi, Kahleb Graham, Ajay Kaul
OBJECTIVES: The inability to burp, known as retrograde cricopharyngeal dysfunction (R-CPD), was initially described in adults. The proposed clinical diagnostic criteria for R-CPD include belching inability, abdominal bloating and discomfort/nausea, postprandial chest pain, and involuntary noises. Botulinum toxin injection to the cricopharyngeal muscle has been reported to be beneficial. High-resolution esophageal impedance-manometry (HRIM) features in adolescent patients with R-CPD have not been described yet...
March 22, 2024: Journal of Pediatric Gastroenterology and Nutrition
https://read.qxmd.com/read/38512437/the-effect-of-oropharyngeal-resting-tremor-on-swallowing-function-in-a-clinical-cohort-of-people-with-parkinson-s-disease
#6
JOURNAL ARTICLE
Matthew Dumican, Kaitlynn Harper, Julia Stankiewicz
Parkinson's Disease (PD) is a progressive neurodegenerative disease, with hallmark symptomology typically consisting of tremor, bradykinesia, and rigidity. Though the classic "pill-rolling" rest tremor in the hand or upper limb are often the most salient, it can occur throughout the body including the lower limbs, jaw, face, or tongue. There have been investigations into other motor related phenomena potentially affecting swallow function in PwPD previously. However, there have been no investigations of how oropharyngeal resting tremor in structures such as the tongue or larynx explicitly affects swallowing physiology...
March 21, 2024: Dysphagia
https://read.qxmd.com/read/38508333/laryngeal-dysfunction-manifesting-as-chronic-refractory-cough-and-dyspnea-laryngeal-physiology-in-respiratory-health-and-disease
#7
REVIEW
Krishna M Sundar, Amanda Stark, Michael J Morris
TOPIC IMPORTANCE: Laryngeal dysfunction as a cause of chronic refractory cough (CRC) and episodic dyspnea is often missed which results in unnecessary testing and delays in diagnosis. Understanding laryngeal roles in breathing and airway protection can help to appreciate the propensity to laryngeal dysfunction with aging, chronic lung disease and sleep apnea. REVIEW FINDINGS: The human larynx is a complex muscular structure that undertakes multiple roles of breathing, vocalization, coughing and swallowing...
March 18, 2024: Chest
https://read.qxmd.com/read/38487993/a-multidisciplinary-approach-to-identifying-and-managing-heterotopic-gastric-inlet-patches
#8
JOURNAL ARTICLE
L Ayres, S Perring, S A R Nouraei
INTRODUCTION: Gastric inlet patches are often incidental, but can also be a treatable cause of laryngo-esophageal symptoms. METHODS: We retrospectively reviewed all patients whose gastric inlet patches were diagnosed following assessment for laryngopharyngeal and swallowing symptoms. Improvement following Argon Plasma Coagulation (APC) was assessed using Minimum Clinically-Important Difference methodology combining voice, throat, and swallowing domains. Correlations between APC response and measures of reflux and mucosal barrier integrity, measured during 24-h pH-impedance manometry, were obtained...
March 15, 2024: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://read.qxmd.com/read/38482576/chemoradiation-to-the-submental-muscles-alters-hyoid-movement-during-swallowing-in-a-rat-model
#9
JOURNAL ARTICLE
Suzanne N King, Abigail Kuntz, Nathan Scott, Brittany Smiley, Andres Portocarrero Bonifaz, Megan Blackburn
Hyolaryngeal dysfunction is a commonly reported swallowing problem after chemoradiation treatment for head and neck cancer. The displacement of the hyolaryngeal complex during swallowing protects the airway and assists in opening the upper esophageal sphincter. Activation of the submental muscles, specifically the mylohyoid and geniohyoid muscles, are thought to facilitate movement of the hyoid. The purpose of this study was to determine if targeted radiation to the submental muscles given concurrently with chemotherapy alters hyolaryngeal displacement one-month after treatment...
March 14, 2024: Journal of Applied Physiology
https://read.qxmd.com/read/38462820/safety-related-outcomes-for-patients-with-a-tracheostomy-and-the-use-of-flexible-endoscopic-evaluation-of-swallowing-fees-for-assessment-and-management-of-swallowing-a%C3%A2-systematic-review
#10
REVIEW
Katherine Morris, Nicholas F Taylor, Amy Freeman-Sanderson
PURPOSE: The purpose of this systematic review was to examine safety-related outcomes for patients with tracheostomy after flexible endoscopic evaluation of swallowing (FEES) to assess and manage their swallow, when compared to other non-instrumental swallow assessments such as clinical swallowing examination (CSE) and/or a modified Evans blue dye test (MEBDT). METHOD: Three databases were searched for articles referring to safety-related outcome data for adults with a tracheostomy, who underwent FEES and CSE and/or MEBDT...
March 10, 2024: International Journal of Speech-language Pathology
https://read.qxmd.com/read/38452933/age-related-impairments-in-ingestion-from-a-large-population-based-sample
#11
JOURNAL ARTICLE
Martine Hennequin, Nada El Osta, Marie-Laure Munoz-Sanchez, Mathilde Vandenberghe Descamps, Valentina A Andreeva, Gilles Feron, Emmanuel Nicolas, Bruno Pereira, Marie-Agnès Peyron, Pierre-Yves Cousson, Claire Sulmont-Rosse, Denise Faulks
OBJECTIVES: Epidemiological data regarding the evolution of problems related to mastication and swallowing with age are lacking. This study aims to (i) describe changes in oral function with age, using data from a large French population, (ii) validate online, self-report uses of an ICF questionnaire in older persons, and (iii) assess whether impairment is related to avoidance of certain foods, xerostomia, body mass index (BMI) and oral health related quality of life (OHRQoL). METHODS: Volunteers aged ≥18 years with internet access completed a series of questionnaires on sociodemographic, anthropometric and oral health characteristics (oral function, Xerostomia Index (XI), OHRQoL, reasons for avoidance of certain food)...
March 5, 2024: Appetite
https://read.qxmd.com/read/38431893/dysphagia-in-open-partial-horizontal-laryngectomy-type-iia-quantitative-analysis-of-videofluoroscopy-using-the-aspekt-method
#12
JOURNAL ARTICLE
Raphaela da Costa Miranda Barbosa, Andressa Silva de Freitas, Rayane Beltrão Alves Cerqueira, Renata Mancopes, Fernando Luiz Dias, Catriona M Steele
Open Partial Horizontal Laryngectomy (OPHL) Type IIa surgery is a conservative surgical technique used in the treatment of laryngeal carcinomas. In this pilot study, we aimed to characterize swallowing function and physiology in a series of patients after OPHL Type IIa surgery through comparison to healthy reference values for quantitative measures for videofluoroscopy. We performed retrospective quantitative analysis of videofluoroscopy recordings of thin liquid swallows for a preliminary sample of 10 male patients...
March 3, 2024: Dysphagia
https://read.qxmd.com/read/38428221/prevalence-and-prognosis-of-cachexia-according-to-the-asian-working-group-for-cachexia-criteria-in-sarcopenic-dysphagia-a-retrospective-cohort-study
#13
JOURNAL ARTICLE
Hidetaka Wakabayashi, Shingo Kakehi, Satoko Mizuno, Tomoko Kinoshita, Sayaka Toga, Masahiro Ohtsu, Shinta Nishioka, Ryo Momosaki
OBJECTIVE: The aim is to examine the prevalence and prognosis of cachexia according to the Asian Working Group for Cachexia (AWGC) criteria in patients with sarcopenic dysphagia. METHODS: A retrospective cohort study was conducted with 271 patients diagnosed with sarcopenic dysphagia out of 467 patients enrolled in the Japanese sarcopenic dysphagia database. Cachexia was diagnosed by the AWGC criteria. The AWGC criteria includes chronic diseases, either or both weight loss (2% or more over 3-6 mo) or low BMI (<21 kg/m2 ), and at least one of the following: anorexia, decreased grip strength (<28 kg in men and <18 kg in women), or elevated C-reactive protein levels (>0...
February 6, 2024: Nutrition
https://read.qxmd.com/read/38403496/nightly-reductions-in-body-temperature-and-effect-of-transmitter-attachment-method-in-free-living-welcome-swallows-hirundoneoxena
#14
JOURNAL ARTICLE
Alice Barratt, Christopher Turbill
Small birds and mammals face similar energetic challenges, yet use of torpor to conserve energy while resting is considered less common among birds, especially within the most specious order Passeriformes. We conducted the first study to record the natural thermoregulatory physiology of any species from the family Hirundinidae, which we predicted would use torpor because of their specialised foraging by aerial pursuit of flying insects, that are less active during cold or windy weather. We used temperature telemetry on wild-living welcome swallows (Hirundo neoxena, 13 to 17 g) and found that skin temperature declined during nightly resting by an average by 5 °C, from daytime minima of 41...
January 28, 2024: Journal of Thermal Biology
https://read.qxmd.com/read/38403087/application-of-3d-printing-technology-for-the-development-of-dose-adjustable-geriatric-and-pediatric-formulation-of-celecoxib
#15
JOURNAL ARTICLE
Henis Patel, Vishvesh Raje, Paulina Maczko, Ketan Patel
Developing safe and effective formulations for the geriatric and pediatric population is a challenging task due to issues of swallowability and palatability. The lack of standardized procedures for pediatric formulations further complicates the process. Manipulating adult formulations for children can lead to suboptimal efficacy and safety concerns. To overcome these challenges, minitablets or spinklets are preferred for the geriatric and pediatric population due to their smaller size and flexible dose adjustment...
February 23, 2024: International Journal of Pharmaceutics
https://read.qxmd.com/read/38395210/apnea-behavior-in-early-and-late-stage-mouse-models-of-parkinson-s-disease-cineradiographic-analysis-of-spontaneous-breathing-acute-stress-and-swallowing
#16
JOURNAL ARTICLE
Lorena Roberta de Souza Mendes Kawamura, Max Sarmet, Priscila Sales de Campos, Sachiko Takehara, Yasuhiro Kumei, Jorge Luis Lopes Zeredo
This study aimed to evaluate the timing and frequency of spontaneous apneas during breathing and swallowing by using cineradiography on mouse models of early/initial or late/advanced Parkinson's disease (PD). C57BL/6J mice received either 6-OHDA or vehicle injections into their right striatum, followed by respiratory movement recordings during spontaneous breathing and swallowing, and a stress challenge, two weeks later. Experimental group animals showed a significantly lower respiratory rate (158.66 ± 32...
February 21, 2024: Respiratory Physiology & Neurobiology
https://read.qxmd.com/read/38385184/serotonin-therapies-for-opioid-induced-disordered-swallow-and-respiratory-depression
#17
JOURNAL ARTICLE
Michael Frazure, In Morimoto, Nathan Fielder, Nicholas Mellen, Kimberly Iceman, Teresa Pitts
Opioids are well-known to cause respiratory depression, but despite clinical evidence of dysphagia, effects of opioids on swallow excitability and motor pattern are unknown. We tested the effects of the clinically-relevant opioid buprenorphine on pharyngeal swallow and respiratory drive in male and female rats. We also evaluated the utility of 5-HT1A agonists (8-OH-DPAT and buspirone) to improve swallowing and breathing following buprenorphine administration. Experiments were performed on 44 freely breathing Sprague Dawley rats anesthetized with sodium pentobarbital...
February 22, 2024: Journal of Applied Physiology
https://read.qxmd.com/read/38385009/the-importance-of-taste-on-swallowing-function
#18
REVIEW
Masahiko Okubo, Motoyoshi Morishita, Tomoko Odani, Hideo Sakaguchi, Takeshi Kikutani, Shoichiro Kokabu
The world's population is aging. Pneumonia is the leading cause of death among the older adults, with aspiration pneumonia being particularly common. Aspiration pneumonia is caused by a decline in swallowing function. Causes can include age-related sarcopenia of swallowing muscles, cognitive decline, cerebrovascular and other diseases or even changes in individual taste preference. Currently, the main treatment approach for dysphagia is resistance training of swallowing-related muscles. This approach has not been effective and establishment of novel methods are required...
2024: Frontiers in Nutrition
https://read.qxmd.com/read/38378686/clinical-characteristics-and-surgical-management-of-facial-infiltrating-lipomatosis-a-single-center-experience
#19
JOURNAL ARTICLE
Hongrui Chen, Bin Sun, Wenwen Xia, Yajing Qiu, Wei Gao, Chen Hua, Xiaoxi Lin
BACKGROUND: Facial infiltrating lipomatosis (FIL) is a rare condition characterized by congenital facial enlargement. Beyond its impact on physical appearance, FIL can also impair essential facial functions such as swallowing, chewing, vision, and breathing, imposing a substantial physiological and psychological burden. Currently, fewer than 80 cases of FIL have been reported, and the characteristics and management strategies for FIL remain unclear. METHODS: We reviewed the clinical, surgical, and radiological records of 39 FIL patients who were treated at our center...
February 20, 2024: Head & Face Medicine
https://read.qxmd.com/read/38372730/imaging-swallowing-function-and-the-mechanisms-driving-dysphagia-in-inclusion-body-myositis
#20
REVIEW
Sharfaraz Salam, Jodi Allen, Mazen M Dimachkie, Michael G Hanna, Pedro M Machado
Sporadic inclusion body myositis (IBM) is a progressive condition which commonly affects patients aged above 40. IBM does not respond to immunosuppression and no proven treatments are available. Up to 80% of patients develop some degree of swallowing impairment during the disease course. Dysphagia is a source of marked morbidity in IBM and predisposes patients to life-threatening complications such as aspiration pneumonia. The pathophysiology behind dysphagia in IBM is not fully understood. Evidence from imaging demonstrates that impaired swallowing is predominantly underpinned by oropharyngeal deficits...
February 16, 2024: Clinical and Experimental Rheumatology
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