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Tongue stimulation

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https://www.readbyqxmd.com/read/29651428/effects-and-mechanisms-of-tastants-on-the-gustatory-salivary-reflex-in-human-minor-salivary-glands
#1
Shizuko Satoh-Kuriwada, Noriaki Shoji, Hiroyuki Miyake, Chiyo Watanabe, Takashi Sasano
The effects and mechanisms of tastes on labial minor salivary gland (LMSG) secretion were investigated in 59 healthy individuals. Stimulation with each of the five basic tastes (i.e., sweet, salty, sour, bitter, and umami) onto the tongue induced LMSG secretion in a dose-dependent manner. Umami and sour tastes evoked greater secretion than did the other tastes. A synergistic effect of umami on LMSG secretion was recognized: a much greater increase in secretion was observed by a mixed solution of monosodium glutamate and inosine 5'-monophosphate than by each separate stimulation...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29649082/transcutaneous-electrical-nerve-stimulation-reduces-resting-pain-in-head-and-neck-cancer-patients-a-randomized-and-placebo-controlled-double-blind-pilot-study
#2
Jennifer E Lee, Carryn M Anderson, Yelena Perkhounkova, Brittany M Sleeuwenhoek, Rebecca R Louison
BACKGROUND: Individuals receiving radiation for head and neck cancer (HNC) often develop painful oral mucositis that impairs function, possibly leading to feeding tubes, hospitalization, and treatment delays. Although pharmacologic medications provide some relief, many report inadequate analgesia and adverse effects. Transcutaneous electrical nerve stimulation (TENS) is a safe, nonpharmacologic intervention; it decreases pain and analgesics and improves function, yet no studies examined TENS for HNC...
April 11, 2018: Cancer Nursing
https://www.readbyqxmd.com/read/29642741/effects-of-transcranial-direct-current-stimulation-over-the-broca-s-area-on-tongue-twister-production
#3
Min Ney Wong, Yanky Chan, Manwa L Ng, Frank F Zhu
PURPOSE: The present study aimed to explore the short-term effect of anodal transcranial direct current stimulation (tDCS) on tongue twister production. METHOD: Thirty healthy native Cantonese adult speakers were randomly assigned to the anodal tDCS group or the sham tDCS group. Anodal tDCS of 2 mA was applied over the Broca's area of the brain. The stimulation lasted for 20 min for the anodal tDCS group and 30 s for the sham tDCS group. The participants were instructed to produce a list of tongue twisters before, immediately after and 4 h after tDCS...
April 11, 2018: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/29592978/hypoglossal-nerve-stimulation-for-obstructive-sleep-apnoea-in-a-patient-with-previous-tongue-laceration
#4
Joel W Jones, Kent Lee, Suzanne Stevens, Chris Larsen
Upper airway stimulation of the tongue using an implantable neurostimulator has recently been approved for select patients with moderate to severe obstructive sleep apnoea (OSA) and intolerance to continuous positive airway pressure therapy. Effective implantation depends on the integrity of the hypoglossal nerve as well as the tongue musculature, notably the genioglossus. Prior trauma to either of these structures may be viewed as a relative contraindication to implantation. We describe a case of successful right hypoglossal nerve implantation in a patient with a history of left cardiac pacemaker placement and severe left penetrating tongue trauma with decreased mobility from contracture and deviation mimicking a hypoglossal nerve palsy...
March 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29590480/anatomic-predictors-of-response-and-mechanism-of-action-of-upper-airway-stimulation-therapy-in-patients-with-obstructive-sleep-apnea
#5
Richard J Schwab, Stephen H Wang, Johan Verbraecken, Olivier M Vanderveken, Paul Van de Heyning, Wim G Vos, Jan W DeBacker, Brendan T Keenan, Quan Ni, Wilfried DeBacker
Study Objectives: Upper airway stimulation has been shown to be an effective treatment for some patients with obstructive sleep apnea. However, the mechanism by which hypoglossal nerve stimulation increases upper airway caliber is not clear. Therefore, the objective of this study was to identify the mechanism of action of upper airway stimulation. We hypothesized that, with upper airway stimulation, responders would show greater airway opening in the retroglossal (base of the tongue) region, greater hyoid movement toward the mandible, and greater anterior motion in the posterior, inferior region of the tongue compared with nonresponders...
March 26, 2018: Sleep
https://www.readbyqxmd.com/read/29580888/characterization-of-mouse-chorda-tympani-responses-evoked-by-stimulation-of-anterior-or-posterior-fungiform-taste-papillae
#6
Stuart A McCaughey
Different gustatory papilla types vary in their locations on the tongue. Distinctions have often made between types, but variation within fungiform papillae has seldom been explored. Here, regional differences in fungiform papillae were investigated by flowing solutions selectively over either an anterior fungiform (AF, tongue tip) or a posterior fungiform (PF, middle third) region as taste-evoked activity was measured in the chorda tympani nerve of C57BL/6J (B6) mice. Significantly larger responses were evoked by NaCl applied to the AF than PF region, and the ENaC blocker amiloride reduced the NaCl response size only for the former...
March 23, 2018: Neuroscience Research
https://www.readbyqxmd.com/read/29560637/-regularity-of-clinical-application-of-lianquan-cv-23-in-chinese-ancient-times-according-to-literature-of-traditional-chinese-medicine
#7
Mei-Jun Deng, Chun-Yan Liu, Yu Xie, Jie-Bin Zhu, Zhen-Hua Xu
OBJECTIVE: To summarize the regularity of application of Lianquan (CV 23) in clinical practice in Chinese ancient times through analysis of ancient traditional Chinese medical (TCM) literature. METHODS: A total of 60 books involving CV 23 from the 1 156 ancient TCM books listed in the fifth edition of Encyclopedia of Traditional Chinese Medicine were collected by using CV 23 as the main keyword and "Sheben" "Benchi", and "Jieben" (the other names of CV 23 in TCM)as the supplementary keywords and analyzed systematically...
March 25, 2018: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29543167/new-thermal-taste-actuation-technology-for-future-multisensory-virtual-reality-and-internet
#8
Kasun Karunanayaka, Nurafiqah Johari, Surina Hariri, Hanis Camelia, Kevin Stanley Bielawski, Adrian David Cheok
Today's virtual reality (VR) applications such as gaming, multisensory entertainment, remote dining, and online shopping are mainly based on audio, visual, and touch interactions between humans and virtual worlds. Integrating the sense of taste into VR is difficult since humans are dependent on chemical-based taste delivery systems. This paper presents the 'Thermal Taste Machine', a new digital taste actuation technology that can effectively produce and modify thermal taste sensations on the tongue. It modifies the temperature of the surface of the tongue within a short period of time (from 25°C to 40 °C while heating, and from 25°C to 10 °C while cooling)...
April 2018: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/29501517/intraoperative-hypoglossal-nerve-mapping-during-carotid-endarterectomy-technical-note
#9
Atsuhiro Kojima, Isako Saga, Mami Ishikawa
BACKGROUND: Hypoglossal nerve deficit is a possible complication caused by carotid endarterectomy (CEA). The accidental injury of the hypoglossal nerve during surgery is one of the major reasons for permanent hypoglossal nerve palsy. In this study, we investigated the usefulness of intraoperative mapping of the hypoglossal nerve to identify this nerve during CEA. METHODS: Five consecutive patients who underwent CEA for the treatment of symptomatic or asymptomatic carotid artery stenosis were studied...
February 28, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29490007/associations-between-human-fungiform-papillae-and-responsiveness-to-oral-stimuli-effects-of-individual-variability-population-characteristics-and-methods-for-papillae-quantification
#10
Maria Piochi, Caterina Dinnella, John Prescott, Erminio Monteleone
Fungiform papillae on human tongue are the proxy structures designated to oral stimuli detection and transduction. However, the role of their density (fungiform papillae/cm2) in explaining oral sensitivity is still controversial. While early studies generally found that the responsiveness to oral stimuli increased as the number of papillae increased, recent large-scale studies failed to confirm this finding.The present paper reviews relevant studies dealing with the relationship between fungiform papillae density and responsiveness to oral sensations including: fundamental tastes, 6-n-propyl-2-thiouracil (PROP) and sensations from trigeminal stimulation...
February 27, 2018: Chemical Senses
https://www.readbyqxmd.com/read/29481884/local-anesthetic-effect-of-docosahexaenoic-acid-on-the-nociceptive-jaw-opening-reflex-in-rats
#11
Kazuki Mitome, Shiori Takehana, Katsuo Oshima, Yoshihito Shimazu, Mamoru Takeda
Although docosahexaenoic acid (DHA) administration suppresses sodium channels in primary afferent sensory neurons, the acute local effect of DHA on the trigeminal nociceptive reflex remains to be elucidated, in vivo. Therefore, the aim of the present study was to investigate whether local administration of DHA attenuates the nociceptive jaw-opening reflex (JOR) in vivo in the rat. The JOR evoked by electrical stimulation of the tongue was recorded by a digastric muscle electromyogram (dEMG) in pentobarbital-anesthetized rats...
February 23, 2018: Neuroscience Research
https://www.readbyqxmd.com/read/29453996/systematic-review-of-botulinum-toxin-treatment-for-oromandibular-dystonia
#12
Cynthia L Comella
Oromandibular dystonia (OMD) is an isolated focal dystonia that affects the muscles of the jaw, lower face and tongue. It is a rare disorder but is associated with significant impairment in quality of life. Treatment with oral medications has not been successful. Surgical interventions, such as deep brain stimulation, may be of benefit but have not been adequately evaluated. Currently, botulinum toxin (BoNT) injections are regarded as the treatment of choice for OMD. However, the evidence supporting this is not available...
February 14, 2018: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29410358/hypoglossal-nerve-stimulation-in-a-pre-clinical-anesthetized-rabbit-model-relevant-to-osa
#13
Girriso F Benderro, Jenniffer Gamble, Matthew A Schiefer, Jonathan Z Baskin, Yeritza Hernandez, Kingman P Strohl
We tested the functional effects of hypoglossal (CNXII) stimulation in the anesthetized rabbit before and after injections of saline into the tongue base to obstruct the airway. Data (n = 6) show little or no effect of CN XII trunk stimulation; however, medial branch stimulation (20-100 Hz; 50-500 μs pulse width, and incremental increases from 10 μA) reduced upper airway resistance. Medial branch stimulation was less effective in reducing resistance than anterior advancement of the hyoid. Endoscopic viewing (n-3) of the retropalate showed this region as the narrowest and dynamically changed by anterior hyoid displacement, with less evident effects than CNXII stimulation...
April 2018: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/29410235/variation-in-thermally-induced-taste-response-across-thermal-tasters
#14
Martha Skinner, Sally Eldeghaidy, Rebecca Ford, Timo Giesbrecht, Anna Thomas, Susan Francis, Joanne Hort
Thermal tasters (TTs) perceive thermally induced taste (thermal taste) sensations when the tongue is stimulated with temperature in the absence of gustatory stimuli, while thermal non tasters (TnTs) only perceive temperature. This is the first study to explore detailed differences in thermal taste responses across TTs. Using thermal taster status phenotyping, 37 TTs were recruited, and the temporal characteristics of thermal taste responses collected during repeat exposure to temperature stimulation. Phenotyping found sweet most frequently reported during warming stimulation, and bitter and sour when cooling, but a range of other sensations were stated...
February 1, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29404821/spexin-in-the-half-smooth-tongue-sole-cynoglossus-semilaevis-molecular-cloning-expression-profiles-and-physiological-effects
#15
Shengpeng Wang, Bin Wang, Songlin Chen
Spexin (SPX), a novel neuropeptide discovered by the bioinformatics approach, has been shown to exert pleiotropic functions in mammals. However, little information regarding the physiological role of SPX is available in teleosts. As a first step, we cloned the spexin gene from a flatfish, the half-smooth tongue sole. The open reading frame (ORF) of tongue sole spexin contained 363 nucleotides encoding a 120 amino acid (aa) preprohormone with a calculated molecular mass and isoelectric point of 14.06 kDa and 5...
February 5, 2018: Fish Physiology and Biochemistry
https://www.readbyqxmd.com/read/29404215/equine-glucagon-like-peptide-1-receptor-physiology
#16
Murad H Kheder, Simon R Bailey, Kevin J Dudley, Martin N Sillence, Melody A de Laat
Background: Equine metabolic syndrome (EMS) is associated with insulin dysregulation, which often manifests as post-prandial hyperinsulinemia. Circulating concentrations of the incretin hormone, glucagon-like peptide-1 (GLP-1) correlate with an increased insulin response to carbohydrate intake in animals with EMS. However, little is known about the equine GLP-1 receptor (eGLP-1R), or whether GLP-1 concentrations can be manipulated. The objectives were to determine (1) the tissue localisation of the eGLP-1R, (2) the GLP-1 secretory capacity of equine intestine in response to glucose and (3) whether GLP-1 stimulated insulin secretion from isolated pancreatic islets can be attenuated...
2018: PeerJ
https://www.readbyqxmd.com/read/29399178/g-csf-producing-oral-carcinoma-with-diffuse-uptake-of-fdg-in-the-bone-marrow-a-case-report
#17
Takeshi Kuroshima, Mayumi Wada, Takehiko Sato, Masashi Takano, Shujiroh Makino
A 78-year-old male patient was referred to the Department of Oral Surgery, Hokuto Hospital (Obihiro, Japan) for painless swelling on the left neck and tongue. Histopathological examination of a biopsy specimen resulted in a diagnosis of squamous cell carcinoma of the tongue. Imaging examinations revealed cervical lymph node metastases on both sides, along with diffuse uptake of 18F-fluorodeoxyglucose (FDG) in the bone marrow of the spine and pelvis. Hematologic tests revealed an increased white blood cell (WBC) count and serum concentrations of granulocyte colony stimulating factor (G-CSF)...
January 2018: Oncology Letters
https://www.readbyqxmd.com/read/29385406/c-reactive-protein-is-associated-with-the-development-of-tongue-squamous-cell-carcinoma
#18
Jianxin Du, Wei Hu, Chengzhe Yang, Yegang Wang, Xiaoying Wang, Pishan Yang
C-reactive protein (CRP) acts as a biomarker reflecting different degrees of inflammation. Accumulating reports have suggested that there is a close relationship between CRP and various cancers. However, the influence of CRP on the development of tongue squamous cell carcinoma (TSCC) remains unclear. The purpose of this study was to investigate the role of CRP in TSCC. The results of immunohistochemical staining and statistical analyses showed that CRP expression was associated with TSCC tumor size, lymph node metastasis and pathological differentiation...
January 27, 2018: Acta Biochimica et Biophysica Sinica
https://www.readbyqxmd.com/read/29380619/the-prevalence-of-ankyloglossia-in-302-newborns-with-breastfeeding-problems-and-sucking-difficulties-in-barcelona-a-descriptive-study
#19
E Ferrés-Amat, T Pastor-Vera, P Rodriguez-Alessi, E Ferrés-Amat, J Mareque-Bueno, E Ferrés-Padró
AIM: Oral and maxillofacial development is influenced by the lingual frenulum and also affects breathing, occlusion, sucking, swallowing, speech, among others. Ankyloglossia in the newborn may result in breastfeeding difficulties: maternal nipple pain and/or erosion or mastitis, poor weight gain and excessively long breastfeeds. The main objective of this work is to study the prevalence of ankyloglossia in newborns with breastfeeding difficulties. MATERIALS AND METHODS: This is a transversal descriptive study of 302 patients, between 0 and 6 months, who attended the hospital as a result of breastfeeding difficulties...
December 2017: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/29376445/exploring-australian-speech-language-pathologists-use-and-perceptions-ofnon-speech-oral-motor-exercises
#20
Anna F Rumbach, Tanya A Rose, Mynn Cheah
PURPOSE: To explore Australian speech-language pathologists' use of non-speech oral motor exercises, and rationales for using/not using non-speech oral motor exercises in clinical practice. METHODS: A total of 124 speech-language pathologists practising in Australia, working with paediatric and/or adult clients with speech sound difficulties, completed an online survey. RESULTS: The majority of speech-language pathologists reported that they did not use non-speech oral motor exercises when working with paediatric or adult clients with speech sound difficulties...
January 29, 2018: Disability and Rehabilitation
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