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https://www.readbyqxmd.com/read/27160834/effect-of-double-door-laminoplasty-on-atypical-symptoms-associated-with-cervical-spondylotic-myelopathy-radiculopathy
#1
Yuqing Sun, Aikeremujiang Muheremu, Kai Yan, Jie Yu, Shan Zheng, Wei Tian
BACKGROUND: Double-door laminoplasty is an effective method in treating patients with cervical spondylosis. Many patients with cervical spondylosis experience a set of atypical symptoms such as vertigo and tinnitus, and wish to know if the surgical treatment for cervical spondylosis can also alleviate those symptoms. The current research was carried out to investigate if atypical symptoms can be alleviated in patients who received laminoplasty for the treatment of cervical spondylosis...
May 10, 2016: BMC Surgery
https://www.readbyqxmd.com/read/25345416/three-dimensional-laparoscopy-and-thoracoscopy-in-children-and-adults-a-prospective-clinical-trial
#2
Marty Zdichavsky, Andreas Schmidt, Tobias Luithle, Sebastian Manncke, Jörg Fuchs
BACKGROUND: Laparoscopic procedures for children and adults already provide many advantages in two-dimensional (2D) vision. Only limited experiences exist for laparoscopic three-dimensional (3D) procedures in vivo. The aim of this prospective trial was to identify indications and limitations of the 3D-system in laparoscopic minimally invasive procedures in children and adults. MATERIAL AND METHODS: In a prospective quality assurance for laparoscopic 3D evaluation in children and adults, a total of 53 consecutive patients (22 children, 31 adults) were included...
June 2015: Minimally Invasive Therapy & Allied Technologies: MITAT
https://www.readbyqxmd.com/read/24346808/evaluation-of-the-effects-of-anti-motion-sickness-drugs-on-subjective-sleepiness-and-cognitive-performance-of-healthy-males
#3
A P Weerts, N Pattyn, P H Van de Heyning, F L Wuyts
This study aimed to investigate the clinical and cognitive side effects of baclofen (10 mg), meclizine (25 mg), dimenhydrinate (40 mg) plus cinnarizine (25 mg) and promethazine (25 mg) plus d-amphetamine (10 mg). The study had a double-blind, placebo controlled, repeated measures design and was conducted on healthy male volunteers. The psychomotor vigilance test, the Sternberg working memory task, the implicit memory test and the automated Operation Span (Ospan) task were performed. The Stanford, the Karolinska and the Epworth Sleepiness scale determined the degree of sleepiness...
July 2014: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/21561392/pregabalin-or-placebo-used-adjunctively-with-levetiracetam-in-refractory-partial-onset-epilepsy-a-post-hoc-efficacy-and-safety-analysis-in-combined-clinical-trials
#4
Basim M Uthman, Mary Almas, Birol Emir, Suzanne Giordano, Teresa Leon
OBJECTIVE: Some patients with epilepsy require treatment with >1 adjunctive antiepileptic drug (AED) to achieve adequate seizure remission. The purpose of this analysis was to evaluate the efficacy and safety of adding adjunctive pregabalin to an AED regimen that included levetiracetam in patients with refractory partial-onset epilepsy. RESEARCH DESIGN AND METHODS: Data from the pregabalin and placebo arms of two placebo-controlled, double-blind, randomized studies of pregabalin in patients who received adjunctive treatment with levetiracetam in addition to ≥1 other AEDs were pooled for this post hoc analysis...
July 2011: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/21320112/the-adverse-event-profile-of-pregabalin-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#5
REVIEW
Gaetano Zaccara, Pierfranco Gangemi, Piero Perucca, Luigi Specchio
PURPOSE: Despite the widespread use of antiepileptic drugs (AEDs) across different neurologic and psychiatric disorders, no study has systematically reviewed all available randomized controlled trials (RCTs) of a given AED to fully uncover its tolerability profile. We aimed at identifying treatment emergent adverse events (AEs) associated with pregabalin through a systematic review and meta-analysis of all available RCTs. We also assessed the association between serious AEs and pregabalin, and investigated whether pregabalin AEs display a dose-response relationship...
April 2011: Epilepsia
https://www.readbyqxmd.com/read/17713805/-oculomotor-trochlear-and-abducens-nerve-palsies
#6
REVIEW
F Staubach, W A Lagrèze
Patients with oculomotor, trochlear, or abducens nerve palsies mainly complain of binocular double vision, but sometimes merely of blurred vision or vertigo. The clinical signs comprise strabismus, pathologic head posture, and disturbed saccades. The characteristic motility deficits are picked up by measuring the strabismic angles at different directions of gaze. Documentation of all three spatial strabismic components is advantageous. Nonparetic strabismus and orbital diseases are important differential diagnoses...
August 2007: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/12660585/-efficacy-and-safety-of-long-acting-carteolol-1-once-daily-a-double-masked-randomized-study
#7
RANDOMIZED CONTROLLED TRIAL
C Trinquand, J-P Romanet, J-P Nordmann, C Allaire et al.
PURPOSE: Carteolol is a beta-adrenoceptor antagonist with intrinsic sympathomimetic activity. Used topically to reduce intraocular pressure, it is typically applied twice daily. In an effort to provide a once-daily dosing regimen, carteolol was formulated with 1% alginic acid. Sodium alginate is a natural polymer product with bioadhesive properties providing increased corneal contact time and a better carteolol penetration through the cornea. The objective of this study was to evaluate the efficacy and safety of long-acting 1% carteolol alginate solution compared to standard 1% carteolol solution...
February 2003: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/12324395/under-rated-neuro-otological-symptoms-hoffman-and-brookler-1978-revisited
#8
REVIEW
Adolfo M Bronstein
In 1978, Hoffman and Brookler published an article in The Laryngoscope to challenge prevailing views on the lack of diagnostic power of certain symptoms often reported by patients to neuro-otologists. Some of these 'under-rated neuro-otological symptoms' include complaints of non-rotational dizziness, blurred and double vision, and the development of visual motion hypersensitivity in patients with balance disorders. In this review, I revisit these visual symptoms in the light of new findings from our laboratory...
2002: British Medical Bulletin
https://www.readbyqxmd.com/read/12227209/stroke-risks-recognition-and-return-to-work
#9
REVIEW
Julie Johnson Zerwic, Kathy Ennen, Holli A DeVon
1. The two major classifications of stroke are ischemic and hemorrhagic. Ischemic strokes account for 75% of all strokes and result from the complete occlusion of an artery. Hemorrhagic strokes, often caused by aneurysm or hypertension, are caused by the rupture of a cerebral blood vessel and bleeding into the surrounding tissue. 2. The signs and symptoms of stroke may include unilateral weakness or paralysis, a sagging of one side of the face, double or blurred vision, vertigo, numbness or tingling, and language disturbances...
August 2002: AAOHN Journal: Official Journal of the American Association of Occupational Health Nurses
https://www.readbyqxmd.com/read/9059197/extradural-morphine-gives-better-pain-relief-than-patient-controlled-i-v-morphine-after-hysterectomy
#10
RANDOMIZED CONTROLLED TRIAL
M Eriksson-Mjöberg, J O Svensson, O Almkvist, A Olund, L L Gustafsson
We examined if patient-controlled analgesia (PCA) with i.v. morphine provided comparable postoperative analgesia after hysterectomy as extradural morphine, without increasing the incidence of side effects. The study (n = 40) was randomized and double-blind. An extradural catheter was inserted before surgery and anaesthesia was standardized. The extradural group received extradural morphine 0.06 mg kg-1 by the end of surgery and a second dose 6 h later. The i.v. group received an i.v. infusion of morphine 0...
January 1997: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/6764165/evaluation-of-amoxapine
#11
REVIEW
J L Kinney, R L Evans
The pharmacology, pharmacokinetics, clinical trials, side effects, and dosage of amoxapine are reviewed. Amoxapine is a tricyclic dibenzoxazepine antidepressant that is chemically similar to the antipsychotic agent loxapine. In animal tests, amoxapine and its metabolites block reuptake of the neurotransmitter norepinephrine, with little effect on serotonin. It is rapidly and virtually completely absorbed when administered orally; peak serum concentrations occur one to two hours after ingestion. Amoxapine is widely distributed throughout body tissues and is 90% bound to serum proteins...
September 1982: Clinical Pharmacy
https://www.readbyqxmd.com/read/4903691/rheumatoid-arthritis-comparison-of-treatment-with-monophenylbutazone-and-phenylbutazone
#12
COMPARATIVE STUDY
J F Woodbury, W A Turner, R Tiongson
A double-blind trial has been carried out to compare the effects of monobutazone and phenylbutazone in ambulant outpatients with rheumatoid arthritis.One patient developed urticaria, vertigo, weakness, tinnitus and blurred vision during monobutazone administration.Side effects occurring in other patients were for the most part trivial.Untoward symptoms were less frequent in patients taking monobutazone than among those on phenylbutazone.The subjects showed neither improvement nor deterioration during administration of ASA, monophenylbutazone or phenylbutazone...
December 27, 1969: Canadian Medical Association Journal
https://www.readbyqxmd.com/read/3894551/transdermal-scopolamine-for-peripheral-vertigo-a-double-blind-study
#13
T Rahko, P Karma
Transdermal scopolamine medication has been evaluated in 30 cases of acute peripheral vertigo. The double blind study revealed favourable effects, e.g. in Menière's disease. The best compromise between effect and side-effects was one active medication patch. The side-effects were those described for scopolamine, such as blurred vision and dryness of the mouth. Transdermal scopolamine seems to offer an alternative form of medication in acute peripheral vertigo.
July 1985: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/1953412/the-epidemiology-of-parkinson-s-disease-a-case-control-study-of-young-onset-and-old-onset-patients
#14
M Stern, E Dulaney, S B Gruber, L Golbe, M Bergen, H Hurtig, S Gollomp, P Stolley
While the cause of Parkinson's disease (PD) remains unknown, recent evidence suggests that certain external factors, ie, environmental agents, may act as neurotoxins, initiating the chain of oxidative reactions that ultimately destroy neurons in the substantia nigra. Young-onset PD might result from greater exposure to a putative neurotoxin. This hypothesis has rekindled interest in the epidemiology of PD. We therefore conducted a detailed analysis of various environmental exposures and early life experiences in 80 patients with old-onset PD (at an age older than 60 years), 69 young-onset patients (younger than 40 years), and 149 age- and sex-matched control subjects...
September 1991: Archives of Neurology
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