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Oropharyngeal dysphagia

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https://www.readbyqxmd.com/read/28319947/effects-of-capsaicin-on-older-patients-with-oropharyngeal-dysphagia-a-double-blind-placebo-controlled-crossover-study
#1
Rui Nakato, Noriaki Manabe, Sayako Shimizu, Kozo Hanayama, Akiko Shiotani, Jiro Hata, Ken Haruma
BACKGROUND/AIMS: The standard of care for older patients with oropharyngeal dysphagia (OD) is poor. Stimulation of transient receptor potential vanilloid 1 might become a pharmacological strategy for these patients. This study aimed to compare the therapeutic effect of film food containing 0.75 µg of capsaicin in these patients. METHODS: In a crossover, randomized trial, 49 patients with OD were provided capsaicin or identical placebo at least 7 days apart. Patients' reported symptoms during repeated swallowing, the volume, pH and substance P (SP) concentrations in saliva, and cervical esophageal wall motion evaluated by ultrasonographic tissue Doppler imaging were obtained before and after capsaicin or placebo administration...
March 21, 2017: Digestion
https://www.readbyqxmd.com/read/28319880/the-importance-of-the-reproducibility-of-oropharyngeal-swallowing-in-amyotrophic-lateral-sclerosis-an-electrophysiological-study
#2
G Cosentino, E Alfonsi, L Mainardi, E Alvisi, F Brighina, F Valentino, B Fierro, G Sandrini, G Bertino, M Berlangieri, R De Icco, M Fresia, A Moglia
OBJECTIVE: To investigate electrophysiologically the reproducibility of oropharyngeal swallowing in patients with ALS. METHODS: We enrolled 26 ALS patients, both with and without clinical signs of dysphagia, and 30 age-matched controls. The reproducibility of the electrophysiological signals related to the oral phase (electromyographic activity of the submental/suprahyoid muscles) and the pharyngeal phase (laryngeal-pharyngeal mechanogram) of swallowing across repeated swallows was assessed...
February 20, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28317607/nutritional-aspects-of-dysphagia-management
#3
C Gallegos, E Brito-de la Fuente, P Clavé, A Costa, G Assegehegn
This chapter describes the nutritional aspects of dysphagia management by starting with the definition of these two conditions (dysphagia and malnutrition) that share three main clinical characteristics: (a) their prevalence is very high, (b) they can lead to severe complications, and (c) they are frequently underrecognized and neglected conditions. From an anatomical standpoint, dysphagia can result from oropharyngeal and/or esophageal causes; from a pathophysiological perspective, dysphagia can be caused by organic or structural diseases (either benign or malignant) or diseases causing impaired physiology (mainly motility and/or perception disorders)...
2017: Advances in Food and Nutrition Research
https://www.readbyqxmd.com/read/28314808/cervical-diffuse-idiopathic-skeletal-hyperostosis-dish-causing-oropharyngeal-dysphagia
#4
Nellowe Candelario, Kevin Bryan Lo, Mario Naranjo
Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory condition characterised by calcification and ossification of the vertebral ligaments. It is most commonly seen to affect the thoracic and lumbar vertebrae and is usually seen among elderly men. The cause of this condition is unknown. Risk factors include male gender, obesity, diabetes and advancing age. The majority of these cases are found incidentally on imaging and patients are generally asymptomatic. Cervical DISH is less common than its thoracic and lumbar counterparts...
March 17, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28282484/a-systematic-review-of-isometric-lingual-strength-training-programs-in-adults-with-and-without-dysphagia
#5
Victoria S McKenna, Bin Zhang, Morgan B Haines, Lisa N Kelchner
Purpose: This systematic review summarizes the effects of isometric lingual strength training on lingual strength and swallow function in adult populations. Furthermore, it evaluates the designs of the reviewed studies and identifies areas of future research in isometric lingual strength training for dysphagia remediation. Method: A comprehensive literature search of 3 databases and additional backward citation search identified 10 studies for inclusion in the review...
March 10, 2017: American Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28275907/changes-in-swallowing-related-quality-of-life-after-endoscopic-treatment-for-zenker-s-diverticulum-using-swal-qol-questionnaire
#6
REVIEW
C Colpaert, O M Vanderveken, K Wouters, P Van de Heyning, C Van Laer
Dysphagia affects the most cardinal of human functions: the ability to eat and drink. The aim of this prospective study was to evaluate swallowing dysfunction in patients diagnosed with Zenker's diverticulum using the Swallowing Quality of Life (SWAL-QOL) questionnaire preoperatively. In addition, SWAL-QOL was used to assess changes in the outcome of swallowing function after endoscopic treatment of Zenker's diverticulum compared to baseline. Pre- and postoperative SWAL-QOL data were analyzed in 25 patients who underwent endoscopic treatment of Zenker's diverticulum between January 2011 and December 2013...
March 9, 2017: Dysphagia
https://www.readbyqxmd.com/read/28275351/botulinum-toxin-is-effective-in-the-management-of-neurogenic-dysphagia-clinical-electrophysiological-findings-and-tips-on-safety-in-different-neurological-disorders
#7
Enrico Alfonsi, Domenico A Restivo, Giuseppe Cosentino, Roberto De Icco, Giulia Bertino, Antonio Schindler, Massimiliano Todisco, Mauro Fresia, Andrea Cortese, Paolo Prunetti, Matteo C Ramusino, Arrigo Moglia, Giorgio Sandrini, Cristina Tassorelli
Background and Aims: Neurogenic dysphagia linked to failed relaxation of the upper esophageal sphincter (UES) can be treated by injecting botulinum toxin (BTX) into the cricopharyngeal (CP) muscle. We compared the effects of this treatment in different neurological disorders with dysphagia, to evaluate its efficacy over time including the response to a second injection. Materials and Methods: Sixty-seven patients with neurogenic dysphagia associated with incomplete or absent opening of the UES (24 with brainstem or hemispheric stroke, 21 with parkinsonian syndromes, 12 with multiple sclerosis, and 10 with spastic-dystonic syndromes secondary to post-traumatic encephalopathy) were treated with the injection of IncobotulinumtoxinA (dose 15-20 U) into the CP muscle under electromyographic guidance...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28264544/efficacy-of-bont-a-and-swallowing-treatment-for-oropharyngeal-dysphagia-recovery-in-a-patient-with-lateral-medullary-syndrome-a-case-study
#8
Irene Battel, Isabella Koch, Federica Biddau, Carla Carollo, Francesco Piccione, Francesca Meneghello, Merico Antonio, Katie Palmer, Rosario Marchese Ragona
BACKGROUND: Wallenberg's syndrome (WS) is known as posterior inferior cerebellar artery syndrome. Dysphagia has been reported from 51% to 94% of the patients, ranging from mild to severe. CASE PRESENTATION: We reported a case of a patient (Male; 52yrs) with WS. MRI showed an intense hypodense area in the dorsolateral part of the ponto-medullary junction. The clinical signs were severe dysphagia, fed by PEG (FOIS 1; PAS 7), sialorrhea, trismus and ataxia. CLINICAL REHABILITATION IMPACT: Dysphagia was treated by botulinum toxin tipe A (BoNT-A), which was injected into the parotid and submandibular salivary glands, temporalis and masseter muscles, cricopharyngeal muscle associated with specific swallowing exercise and food trails...
March 6, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28244575/pharyngeal-residue-and-aspiration-and-the-relationship-with-clinical-nutritional-status-of-patients-with-oropharyngeal-dysphagia-submitted-to-videofluoroscopy
#9
D L Oliveira, E A M Moreira, M B de Freitas, J de A Gonçalves, A M Furkim, P Clavé
OBJECTIVES: The aim of this study was to investigate the association between the videofluoroscopic (VFS) signs of impaired efficacy (pharyngeal residue) and safety (aspiration) swallowing and the clinical/nutritional status of patients with suspect of dysphagia. DESIGN: A cross-sectional study was conducted with patients submitted to videofluoroscopy. SETTING AND PARTICIPANTS: Data of 76 patients were analyzed between March 2011 and December 2014...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28204979/one-year-swallowing-outcomes-in-patients-treated-with-prophylactic-gabapentin-during-radiation-based-treatment-for-oropharyngeal-cancer
#10
Heather M Starmer, WuYang Yang, Christine G Gourin, Rachit Kumar, Bronwyn Jones, Todd McNutt, Sierra Cheng, Harry Quon
Recent investigations by our study team have demonstrated patients using gabapentin for pain management during chemoradiotherapy (CRT) do well maintaining swallowing during treatment with less need for narcotic pain medication, PEG dependence, weight loss, and short-term swallowing morbidity. The purpose of this investigation was to characterize the long-term swallowing function of these patients 1-year following treatment. Sequential patients receiving CRT for oropharyngeal cancer and concurrent gabapentin were evaluated 1-year following treatment for swallowing outcomes...
February 15, 2017: Dysphagia
https://www.readbyqxmd.com/read/28195753/subjective-assessment-of-videofluoroscopic-swallow-studies
#11
Janet W Lee, Derrick R Randall, Lisa M Evangelista, Maggie A Kuhn, Peter C Belafsky
Objective The videofluoroscopic swallow study (VFSS) is the gold standard diagnostic tool to evaluate oropharyngeal dysphagia. Although objective measurements on VFSS have been described, there is no universal method of analysis, and the majority of clinicians use subjective interpretation alone. The purpose of this investigation was to evaluate the accuracy of subjective VFSS analysis. Study Design Double-blinded experiment. Setting Tertiary care laryngology center. Subjects and Methods Seventy-six de-identified videos from VFSS evaluations of patients with dysphagia were presented to blinded, experienced speech-language pathologists and laryngologists individually...
February 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28176891/prevalence-of-swallowing-dysfunction-screened-in-swedish-cohort-of-copd-patients
#12
Margareta Gonzalez Lindh, Monica Blom Johansson, Margareta Jennische, Hirsh Koyi
BACKGROUND: COPD is a common problem associated with morbidity and mortality. COPD may also affect the dynamics and coordination of functions such as swallowing. A misdirected swallow may, in turn, result in the bolus entering the airway. A growing body of evidence suggests that a subgroup of people with COPD is prone to oropharyngeal dysphagia. The aim of this study was to evaluate swallowing dysfunction in patients with stable COPD and to determine the relation between signs and symptoms of swallowing dysfunction and lung function (forced expiratory volume in 1 second percent predicted)...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28159343/palatal-lift-prosthesis-for-bolus-transport-in-a-patient-with-dysphagia-a-clinical-report
#13
Tomohisa Ohno, Norimasa Katagiri, Ichiro Fujishima
A palatal lift prosthesis (PLP) is an intraoral device that provides lift for the soft palate. The usual purpose of a PLP is to reduce nasopharyngeal reflux and the hypernasal speech caused by velopharyngeal incompetence. However, for this patient, the main purpose was to relieve a functional blockage at the oropharyngeal isthmus by suspending the soft palate. A PLP with soft and flexible lift was applied in a patient with a traumatic brain injury and dysphagia. The PLP improved oropharyngeal bolus transit time by relieving the blockage at the oropharyngeal isthmus...
January 31, 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28155281/preliminary-psychometric-performance-of-the-neonatal-feeding-assessment-scale
#14
Mari Viviers, Alta Kritzinger, Bart Vinck, Marien Graham
OBJECTIVE: The objective was to determine the preliminary psychometric performance of a new clinical feeding scale to diagnose oropharyngeal dysphagia (OPD) in neonates. METHODS: Twenty neonates with a median gestational age of 35 weeks were evaluated using the Neonatal Feeding Assessment Scale (NFAS) and modified barium swallow studies (MBSS). The results were compared. RESULTS: Nine of the 20 participants presented with OPD on the NFAS. Comparison of the scale's results with instrumental MBSS indicated that all participants without OPD were correctly excluded (100% sensitivity)...
January 30, 2017: South African Journal of Communication Disorders. die Suid-Afrikaanse Tydskrif Vir Kommunikasieafwykings
https://www.readbyqxmd.com/read/28128886/swallowing-outcomes-for-patients-with-oropharyngeal-squamous-cell-carcinoma-treated-with-primary-chemo-radiation-therapy-receiving-either-prophylactic-gastrostomy-or-reactive-nasogastric-tube-a-prospective-cohort-study
#15
D Goff, S Coward, A Fitzgerald, V Paleri, J Moor, J M Patterson
OBJECTIVES: There is currently no consensus on the optimal feeding route for an oropharyngeal squamous cell cancer (OPSCC) patient without pre-existing dysphagia undergoing chemoradiotherapy (CRT). This study aims to compare the swallowing outcomes for OPSCC patients fed via either prophylactic RIG (pRIG) or reactive naso-gastric tube (rNGT). DESIGN: A prospective cohort study. SETTING: Four head and neck cancer centres in the North of England Cancer Network...
January 27, 2017: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28124628/comparison-of-swallowing-outcomes-of-laryngotracheal-separation-versus-total-laryngectomy-in-a-validated-ovine-model-of-profound-oropharyngeal-dysphagia
#16
COMPARATIVE STUDY
N N Venkatesan, C M Johnson, M T Siddiqui, D J Cates, M A Kuhn, G N Postma, P C Belafsky
OBJECTIVES: To validate the ovine model of profound oropharyngeal dysphagia and compare swallowing outcomes of laryngotracheal separation with those of total laryngectomy. METHODS: Under real-time fluoroscopy, swallowing trials were conducted using the head and neck of two Dorper cross ewes and one human cadaver, secured in lateral fluoroscopic orientation. Barium trials were administered at baseline, pre- and post-laryngohyoid suspension, following laryngotracheal separation, and following laryngectomy in the ovine model...
April 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28119831/increased-bolus-volume-effect-on-delayed-pharyngeal-swallowing-response-in-post-stroke-oropharyngeal-dysphagia-a-pilot-study
#17
Jin-Woo Park, Gyu-Jeong Sim, Dong-Chan Yang, Kyoung-Hwan Lee, Ji-Hea Chang, Ki-Yeun Nam, Ho-Jun Lee, Bum-Sun Kwon
OBJECTIVE: To confirm a relationship between the pharyngeal response and bolus volume, and examine whether increasing the fluid bolus volume can improve penetration and aspiration for stroke dysphagic patients. METHODS: Ten stroke patients with a delayed pharyngeal response problem confirmed by a videofluoroscopic swallowing study (VFSS) were enrolled. Each subject completed two swallows each of 2 mL, 5 mL, and 10 mL of barium liquid thinned with water. The pharyngeal delay time (PDT) and penetration-aspiration scale (PAS) were measured and the changes among the different volumes were analyzed...
December 2016: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28057951/stability-of-levodopa-carbidopa-rectal-suspensions
#18
Ronald F Donnelly
Objective: The combination of levodopa and carbidopa (L/C) is used as an effective therapy for treating Parkinson's disease; however when oropharyngeal dysphagia develops or when insertion of an nasogastric tube is not possible, then rectal administration could be used. To reduce compounding workload and establish a beyond use date, this study was conducted to determine the stability of 2 L/C rectal suspension formulations when stored at either 22°C or 5°C. Methods: Two formulations of L/C rectal suspension were compounded and then packaged in amber polypropylene bottles...
December 2016: Hospital Pharmacy
https://www.readbyqxmd.com/read/28032947/controversies-in-the-management-of-caustic-ingestion-injury-an-evidence-based-review
#19
J H Bird, S Kumar, C Paul, J D Ramsden
BACKGROUND: Caustic ingestion of acid or alkaline substances can cause damage to the upper respiratory and upper digestive tract. Initial presentation following caustic ingestion can include oropharyngeal pain, dysphagia and stridor. It is due to this clinical presentation that the resident otolaryngologist is consulted to review and examine these patients to assess for airway compromise and commence initial management and care until airway concern has passed. OBJECTIVE OF REVIEW: This review aims to provide evidence-based guidance in the management of those presenting with acute ingestion injury so that informed initial medical therapy can be commenced and appropriate investigations are arranged to optimize patient outcome...
December 29, 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/28018753/genetic-determinants-of-swallowing-impairment-recovery-and-responsiveness-to-treatment
#20
REVIEW
Alicja Raginis-Zborowska, Neil Pendleton, Shaheen Hamdy
PURPOSE OF REVIEW: Here we review the latest literature and evidence in the field of genetics and determinants of swallowing and its treatments-specifically, this is a very recent concept in the field of oropharyngeal dysphagia, with only now an emerging research interest in the relationship between our genetic makeup and the effect this has on swallowing function and dysfunction. As such our review will look at preclinical, clinical and hypothesis generating research covering all aspects of the genetics of swallowing, giving new importance to the genotype-phenotype influences pertaining to dysphagia and its recovery...
2016: Current Physical Medicine and Rehabilitation Reports
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