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Oropharyngeal dysphagia

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https://www.readbyqxmd.com/read/29665158/peanut-gastro-intestinal-delivery-oral-immunotherapy-in-adolescents-results-of-the-build-up-phase-of-a-randomized-double-blind-placebo-controlled-trial-pita-study
#1
Jean-Luc Fauquert, Elodie Michaud, Bruno Pereira, Lise Bernard, Nelly Gourdon-Dubois, Paul-Olivier Rouzaire, Emmanuelle Rochette, Etienne Merlin, Bertrand Evrard
BACKGROUND: Oral immunotherapy to peanut is effective in desensitizing patients but has significant side effects including anaphylaxis and gastro-intestinal symptoms. In most protocols peanut is administered in a vehicle food. OBJECTIVE: In an exclusively adolescent population, we tested a new approach using sealed capsules of peanut (Gastro-Intestinal Delivery Oral Immunotherapy or GIDOIT) in order to bypass the upper gastro-intestinal tract. The primary aim was to assess the efficacy of the oral build-up phase of GIDOIT and the secondary aim to analyse its safety...
April 17, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29648522/the-impact-of-recurrent-laryngeal-nerve-lesion-on-oropharyngeal-muscle-activity-and-sensorimotor-integration-in-an-infant-pig-model
#2
Katherine R DeLozier, Francois David Henry Gould, Jocelyn Ohlemacher, Allan J Thexton, Rebecca Z German
The successful performance of a swallow requires dynamic integration, between a wide range of sensory inputs and muscle activities, to produce the coordinated kinematics of oropharyngeal structures. Damage to the recurrent laryngeal nerve (RLN) produces dysphagia in infants, with food or liquid entering the airway, despite this nerve having minimal direct sensory or motor connections to the act of swallowing, apart from vocal fold closure. Previous results have demonstrated that a complete RLN lesion disrupts both performance and kinematics prior to initiation of the pharyngeal swallow in infants...
April 12, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29621788/characteristics-of-early-oropharyngeal-dysphagia-in-patients-with-multiple-system-atrophy
#3
Hyun Haeng Lee, Han Gil Seo, Kwang-Dong Kim, Seung Hak Lee, Woo Hyung Lee, Byung-Mo Oh, Woong-Woo Lee, Yoon Kim, Aryun Kim, Han-Joon Kim, Beomseok Jeon, Tai Ryoon Han
BACKGROUND/AIMS: Dysphagia, a symptom of multiple system atrophy (MSA), is a major clinical concern. In this study, we investigate the characteristics of early oropharyngeal dysphagia (OD) in patients with MSA, and the differences between MSA subtypes. METHODS: Patients enrolled in the study had previously been diagnosed with MSA at the clinic of the Department of Neurology, and had been referred for a videofluoroscopic swallowing study (VFSS), between 2005 and 2014, to check for dysphagia...
April 5, 2018: Neuro-degenerative Diseases
https://www.readbyqxmd.com/read/29619524/impact-of-formal-training-on-agreement-of-videofluoroscopic-swallowing-study-interpretation-across-and-within-disciplines
#4
Alice K Silbergleit, Diana Cook, Scott Kienzle, Erica Boettcher, Daniel Myers, Denise Collins, Edward Peterson, Matthew A Silbergleit, Richard Silbergleit
PURPOSE: Formal agreement studies on interpretation of the videofluoroscopic swallowing study (VFSS) procedure among speech-language pathologists, radiology house officers, and staff radiologists have not been pursued. Each of these professions participates in the procedure, interprets the examination, and writes separate reports on the findings. The aim of this study was to determine reliability of interpretation between and within the disciplines and to determine if structured training improved reliability...
April 4, 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29611876/screening-for-oropharyngeal-dysphagia-in-older-adults-a-systematic-review-of-self-reported-questionnaires
#5
REVIEW
Hipólito V Magalhães Junior, Leandro de Araújo Pernambuco, Kenio C Lima, Maria Angela F Ferreira
BACKGROUND: Oropharyngeal dysphagia is a swallowing disorder with signs and symptoms which may be present in older adults, but they are rarely noticed as a health concern by older people. The earliest possible identification of this clinical condition is needed by self-reported population-based screening questionnaire, which are valid and reliable for preventing risks to nutritional status, increased morbidity and mortality. OBJECTIVE: The aim of this systematic review was to identify self-reported screening questionnaires for oropharyngeal dysphagia in older adults to evaluate their methodological quality for population-based studies...
April 3, 2018: Gerodontology
https://www.readbyqxmd.com/read/29607447/oropharyngeal-dysphagia-evaluation-tools-in-adults-with-solid-malignancies-outside-the-head-and-neck-and-upper-gi-tract-a-systematic-review
#6
REVIEW
Ciarán Kenny, Órla Gilheaney, Declan Walsh, Julie Regan
Dysphagia is often associated with head and neck and upper gastrointestinal (GI) tract cancers. Evidence suggests that those with solid malignancies in other primary sites may also have swallowing difficulties. Timely and accurate identification of dysphagia is important given the impact it has on hydration, medical treatment, nutrition, prognosis, and quality of life. A systematic review was conducted to identify swallow screening, evaluation, and quality of life tools for those with solid malignancies outside the head and neck and upper GI tract...
April 2, 2018: Dysphagia
https://www.readbyqxmd.com/read/29606914/an-introduction-to-item-response-theory-and-rasch-analysis-of-the-eating-assessment-tool-eat-10
#7
Jacob Kean, Darrel S Brodke, Joshua Biber, Paul Gross
Item response theory has its origins in educational measurement and is now commonly applied in health-related measurement of latent traits, such as function and symptoms. This application is due in large part to gains in the precision of measurement attributable to item response theory and corresponding decreases in response burden, study costs, and study duration. The purpose of this paper is twofold: introduce basic concepts of item response theory and demonstrate this analytic approach in a worked example, a Rasch model (1PL) analysis of the Eating Assessment Tool (EAT-10), a commonly used measure for oropharyngeal dysphagia...
March 2018: Brain Impairment: a Multidisciplinary Journal of the Australian Society for the Study of Brain Impairment
https://www.readbyqxmd.com/read/29575051/relationships-between-dysphagia-and-tongue-pressure-during-swallowing-in-parkinson-s-disease-patients
#8
Yoshitomo Minagi, Takahiro Ono, Kazuhiro Hori, Shigehiro Fujiwara, Yoshitsugu Tokuda, Kazuhiro Murakami, Yoshinobu Maeda, Saburo Sakoda, Masaru Yokoe, Masahito Mihara, Hideki Mochizuki
Although dysphagia is a life-threatening problem in patients with Parkinson's disease (PD), the pathophysiology of oropharyngeal dysphagia is yet to be understood. The present study investigated the tongue motor function during swallowing in relation with dysphagia and the severity of PD. Thirty PD patients (14 males and 16 females; average age, 69.4 years), Hoehn and Yahr stage II-IV, in Osaka University Hospital are participated in this study. During swallowing 5 ml of water, tongue pressure on the hard palate was measured using a sensor sheet with 5 measuring points...
March 25, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29573418/short-and-long-term-outcomes-of-oropharyngeal-cancer-care-in-the-elderly
#9
Kevin Motz, Robert J Herbert, Carole Fakhry, Harry Quon, Hyunseok Kang, Ana P Kiess, David W Eisele, Wayne M Koch, Kevin D Frick, Christine G Gourin
OBJECTIVE: To examine associations between pretreatment variables, short-term and long-term swallowing and airway impairment, and survival in elderly patients (age > 65 years) treated for oropharyngeal squamous cell cancer (SCCA). STUDY DESIGN: Retrospective analysis of Surveillance, Epidemiology, and End Results (SEER)-Medicare data. METHODS: Longitudinal data from 666 patients diagnosed with oropharyngeal SCCA from 2004 to 2007 were evaluated using cross-tabulations, multivariate logistic regression, and survival analysis...
March 24, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29573064/prevalence-risk-factors-and-complications-of-oropharyngeal-dysphagia-in-stroke-patients-a-cohort-study
#10
L Rofes, D Muriana, E Palomeras, N Vilardell, E Palomera, D Alvarez-Berdugo, V Casado, P Clavé
BACKGROUND: Oropharyngeal dysphagia (OD) is a prevalent poststroke condition with severe complications and increased mortality. Poststroke OD prevalence varies among studies and there is little evidence of its related risk factors and associated complications. OBJECTIVE: to evaluate the prevalence of OD after stroke and the risk factors and associated complications. METHODS: We performed a prospective longitudinal study of stroke patients consecutively admitted to a general hospital...
March 23, 2018: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29571543/dysphagia-in-children
#11
Kimberly L Duffy
Speech-Language Pathologists (SLP) play an integral role in evaluating and treating pediatric patients with dysphagia related to aerodigestive disorders. Non-supportive anatomy, cardio-respiratory and medical status, state control, neurologic functioning, postural stability and control, gastrointestinal functioning, hunger and satiation, developmental abilities, oral-motor skills, oral/pharyngeal reflexes, airway protection and secretion management can create barriers to successful oral feeding. Swallowing is broken down into four phases and difficulties can occur during any phase or in combination with another phase of swallowing...
March 2018: Current Problems in Pediatric and Adolescent Health Care
https://www.readbyqxmd.com/read/29561407/primary-cervical-ganglioneuroblastoma-a-case-report
#12
Dan Lu, Jun Liu, Yuan Chen, Fei Chen, Hui Yang
RATIONALE: Ganglioneuroblastoma is usually located in the adrenal gland, retroperitoneal ganglia, or posterior mediastinum, but rarely occurs in the parapharyngeal space. PATIENT CONCERNS: A 4-year-old girl presented with complaint of progressive inspiratory dyspnea and dysphagia, accompanying left-side Horner's syndrome. DIAGNOSE: Computed tomography (CT) scan revealed a giant mass with irregular low density in left oropharyngeal and posterior pharyngeal wall...
March 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29555725/predicting-respiratory-hospital-admissions-in-young-people-with-cerebral-palsy
#13
Amanda Marie Blackmore, Natasha Bear, Eve Blair, Katherine Langdon, Lisa Moshovis, Kellie Steer, Andrew C Wilson
OBJECTIVE: To determine the early predictors of respiratory hospital admissions in young people with cerebral palsy (CP). DESIGN: A 3-year prospective cohort study using linked data. PATIENTS: Children and young people with CP, aged 1 to 26 years. MAIN OUTCOME MEASURES: Self-reported and carer-reported respiratory symptoms were linked to respiratory hospital admissions (as defined by the International Statistical Classification of Diseases and Related Health Problems 10th Revision codes) during the following 3 years...
March 19, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29554404/relationship-between-dysarthria-and-oral-oropharyngeal-dysphagia-the-current-evidence
#14
Brandon J Wang, Felicia L Carter, Kenneth W Altman
There is a high prevalence of dysphagia among patients with neuromuscular diseases and cerebrovascular diseases, and its consequences can be profound. However, the correlation between dysarthria and oral-oropharyngeal dysphagia remains unclear. We conducted a literature review to define the clinical presentation of both dysarthria and dysphagia in patients with neuromuscular and cerebrovascular diseases. We performed a systematic PubMed search of the English-language literature since 1995. Objective and subjective outcomes instruments were identified for both dysarthria and dysphagia...
March 2018: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/29549900/long-term-quality-of-life-and-psycho-social-outcomes-after-oropharyngeal-cancer-surgery-and-radial-forearm-free-flap-reconstruction-a-gettec-prospective-multicentric-study
#15
Alexandre Bozec, Pierre Demez, Jocelyn Gal, Emmanuel Chamorey, Marie-Yolande Louis, David Blanchard, Dominique De Raucourt, Jean-Claude Merol, Esteban Brenet, Olivier Dassonville, Gilles Poissonnet, José Santini, Frédéric Peyrade, Karen Benezery, Maria Lesnik, Etienne Berta, Pierre Ransy, Emmanuel Babin
OBJECTIVE: To assess long-term quality of life (QoL) and psycho-social outcomes, and to determine their predictive factors after oropharyngeal cancer (OPC) surgery and radial forearm free-flap (RFFF) reconstruction. METHODS: Patients who had undergone OPC surgery and RFFF reconstruction who were still alive and disease-free at least 1 year after surgery were enrolled in this prospective multicentric study. Patients completed the European Organization for Research and Treatment of Cancer (EORTC) Core (QLQ-C30) and Head and Neck Cancer (QLQ-H&N35) QoL questionnaires, the Voice Handicap Index (VHI-10) questionnaire and the Hospital Anxiety and Depression Scale (HADS)...
March 2018: Surgical Oncology
https://www.readbyqxmd.com/read/29524199/self-pressurized-air-q-%C3%A2-intubating-laryngeal-airway-versus-the-lma-%C3%A2-classic%C3%A2-a-randomized-clinical-trial
#16
Sang Hee Ha, Min-Soo Kim, Jiwoo Suh, Jong Seok Lee
PURPOSE: The self-pressurized air-Q® (air-Q SP) intubating laryngeal airway is a relatively new supraglottic airway (SGA) device. The intracuff pressure of air-Q dynamically equilibrates with the airway pressure and adjusts to the patient's pharyngeal and periglottic anatomy, potentially providing improved airway fit and seal. The aim of this prospective randomized study was to compare the clinical performance of air-Q to the LMA® Classic™ SGA. METHODS: Adult patients requiring general anesthesia for elective surgery were prospectively enrolled and randomly assigned to either air-Q SP or the LMA Classic SGA...
February 6, 2018: Canadian Journal of Anaesthesia, Journal Canadien D'anesthésie
https://www.readbyqxmd.com/read/29522797/effect-of-bolus-volume-and-flow-time-on-temporospatial-coordination-in-oropharyngeal-pressure-production-in-healthy-subjects
#17
Jitsuro Yano, Yoichiro Aoyagi, Takahiro Ono, Kazuhiro Hori, Wakami Yamaguchi, Shigehiro Fujiwara, Isami Kumakura
The effects of bolus volume and flow time on the sequential coordination of tongue pressure (TP) and pharyngeal pressure (PP), which are important in the biomechanics of swallowing, are unclear. In this study, we measured TP and PP simultaneously in 10 healthy adults at multiple points during dry swallowing and the swallowing of 5 ml and 15 ml of liquids with different viscosities, and investigated changes in the timing of the onset, peak, and offset of these pressures. TP was measured using a sensor sheet system with five measuring points on the hard palate, and PP was measured using a manometry catheter with four measuring points...
March 6, 2018: Physiology & Behavior
https://www.readbyqxmd.com/read/29507032/following-leads-connecting-dysphagia-to-mixed-connective-tissue-disease
#18
Rita de Sousa Gameiro, Ana Isabel Alves Reis, Ana Cristina Grilo, Carla Noronha
Mixed connective tissue disease (MCDT) is a rare condition characterised by the presence of high titres of anti-U1 ribonucleoprotein antibodies and selected clinical features of systemic lupus erythematosus, systemic sclerosis and polymyositis/dermatomyositis. Early symptoms are non-specific, including easy fatigability, myalgia, arthralgia and Raynaud's phenomenon. Some reports emphasised the favourable outcome and excellent response to glucocorticoids, but there are contradictory studies reporting worse prognosis...
March 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29466260/project-situp-an-interdisciplinary-quality-improvement-initiative-to-reduce-aspiration-pneumonia
#19
Mary Beth OʼMalley, Rebecca L Trotta, Jeffrey Rohrbach, Vivek Ahya, Christine Bradway
The purpose of this quality improvement initiative was to improve oropharyngeal dysphagia screening and reduce aspiration pneumonia rates on 3 inpatient hospital medical units. Guided by a Plan-Do-Study-Act methodology, an interdisciplinary health team developed and implemented a systematic process for oropharyngeal dysphagia screening and management. As a result, use of the screening protocol increased, timely initiation of speech language pathology consultations increased, and aspiration pneumonia rates decreased...
April 2018: Journal of Nursing Care Quality
https://www.readbyqxmd.com/read/29460161/saliva-changes-in-parkinson-s-disease-patients-after-injection-of-botulinum-neurotoxin-type-a
#20
Janne Tiigimäe-Saar, Tiia Tamme, Marika Rosenthal, Liis Kadastik-Eerme, Pille Taba
Patients with Parkinson's disease (PD) are compromised by poor oral condition due to oropharyngeal bradykinesia, dysphagia, and the side effects of treatment. Intrasalivary gland injections of Botulinum neurotoxin type A (BNT-A) have been known to treat sialorrhea effectively in these patients. However, the decreased amount of saliva reduces self-cleaning ability that deteriorates oral hygiene and increases dental caries. The aim of this study was to determine the changes in the oral microflora and saliva in patients with PD treated for sialorrhea by means of sonography-controlled BNT-A injections into the bilateral parotid and submandibular glands...
February 19, 2018: Neurological Sciences
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