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https://www.readbyqxmd.com/read/29244952/metabolic-responses-of-mytilus-galloprovincialis-to-fullerenes-in-mesocosms-exposure-experiments
#1
Josep Sanchís, Marta Llorca, Mar Olmos, Gabriella Francesca Schirinzi, Cristina Bosch-Orea, Esteban Abad, Damia Barcelo, Marinella Farre
In this study, Mediterranean mussels (Mytilus galloprovincialis) were exposed through the diet to fullerene soot, at three concentrations in parallel to a control group. Their metabolomics response was assessed by high-performance liquid chromatography coupled to high-resolution mass spectrometry (HPLC-HRMS). The experiments were conducted in marine mesocosms, during 35 days (7 days of acclimatization, 21 days of exposure and 7 seven days of depuration). Real conditions were emulated in terms of physicochemical conditions of the habitat...
December 15, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/29232646/determination-of-uv-filters-in-human-breast-milk-using-turbulent-flow-chromatography-and-babies-daily-intake-estimation
#2
Daniel Molins-Delgado, María Del Mar Olmo-Campos, Gemma Valeta-Juan, Vanessa Pleguezuelos-Hernández, Damià Barceló, M Silvia Díaz-Cruz
UV filters (UV-Fs) are a group of hormonally active chemical compounds used to protect against the deleterious effects of UVA and UVB solar radiation, which are currently present in most consumer goods (personal care products, plastics, fabrics, paints, etc). Last years the concern about these emerging contaminants has been on the rise, and increasing efforts are being taken in order to properly asses the hazard that the exposure to these compounds in the early stages of life may pose. In this study, a new method for the analysis of 11 UV-Fs residues in human breast milk samples has been developed...
December 9, 2017: Environmental Research
https://www.readbyqxmd.com/read/29223069/neuropsychological-and-clinical-heterogeneity-of-cognitive-impairment-in-patients-with-multiple-system-atrophy
#3
Lorena Broseghini Barcelos, Flávia Saad, Carla Giacominelli, Roberta Arb Saba, Patrícia Maria de Carvalho Aguiar, Sonia Maria Azevedo Silva, Vanderci Borges, Paulo Henrique Ferreira Bertolucci, Henrique Ballalai Ferraz
OBJECTIVE: We evaluated neuropsychological tests to compare cognitive impairment between two types of multiple system atrophy: predominant parkinsonism (MSA-P) and predominant cerebellar ataxia (MSA-C). PATIENTS AND METHODS: This cross-sectional study included 14 patients diagnosed with MSA: four with MSA-C and ten with MSA-P. Presence of motor symptoms was determined by using the Unified Rating MSA Scale (URMSAS). Non-motor symptoms were evaluated by the Short Form Health Survey (SF-36), Scales for Outcomes in Parkinson's disease Autonomic (SCOPA-AUT), Hospital Anxiety and Depression Scale (HADS), and Beck Depression Inventory (BDI)...
October 31, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29211104/surveillance-of-seroepidemiology-and-morbidity-of-chagas-disease-in-the-negro-river-brazilian-amazon
#4
José Rodrigues Coura, Angela Cv Junqueira, João Marcos Bb Ferreira
BACKGROUND: Chagas disease in the Brazilian Amazon Region was previously regarded as an enzootic disease of wild animals. More recently, in situations where humans have penetrated the wild ecotope or where triatomines and/or wild animals (marsupials) have invaded human homes resulting in disease transmission, Chagas disease has come to be regarded as an anthropozoonosis. We found that the highest incidence of infection due to Trypanosoma cruzi and Chagas disease occurred among piassaba fibre gatherers and their families...
January 2018: Memórias do Instituto Oswaldo Cruz
https://www.readbyqxmd.com/read/29209877/effects-of-fish-and-grape-seed-oils-as-core-of-haloperidol-loaded-nanocapsules-on-oral-dyskinesia-in-rats
#5
Dalila Moter Benvegnú, Katiane Roversi, Raquel Cristine Silva Barcelos, Fabíola Trevizol, Camila Simonetti Pase, Hecson Jesser Segat, Verônica Tironi Dias, Ana Luiza Savian, Bruna Lopes Piccoli, Jaqueline Piccolo, Carlos Severo Dutra-Filho, Tatiana Emanuelli, Cristiane de Bona da Silva, Ruy Carlos Ruver Beck, Marilise Escobar Burger
Haloperidol is a widely used antipsychotic, despite the severe motor side effects associated with its chronic use. This study was carried out to compare oral dyskinesia induced by different formulations of haloperidol-loaded nanocapsules containing caprylic/capric triglycerides, fish oil or grape seed oil (GSO) as core, as well as free haloperidol. Haloperidol-loaded lipid-core nanocapsules formulations were prepared, physicochemical characterized and administered (0.5 mg kg-1-ip) to rats for 28 days. Oral dyskinesia was evaluated acutely and subchronically and after that cell viability and free radical generation in cortex and substantia nigra...
December 5, 2017: Neurochemical Research
https://www.readbyqxmd.com/read/29205857/bionomics-of-livestock-associated-culicoides-biting-midge-bluetongue-virus-vectors-under-laboratory-conditions
#6
C Barceló, M A Miranda
This research contributes to knowledge of the basic bionomic parameters of vector and non-vector Culicoides species. Field-collected gravid C. imicola and Obsoletus complex showed the longest lifespans in laboratory conditions. Culicoides paolae and C. circumscriptus seemed to be the most suitable species for laboratory rearing in view of their high oviposition rates, short lifecycles, long adult lifespans and female-biased sex ratios.
December 4, 2017: Medical and Veterinary Entomology
https://www.readbyqxmd.com/read/29205761/cooperative-formation-of-long-range-ordering-in-water-ad-layers-on-fe3o4-111
#7
Francesca Mirabella, Eman Zaki, Francisco Ivars-Barcelo, Xiaoke Li, Joachim Paier, Joachim Sauer, Shamil Shaikhutdinov, Hans-Joachim Freund
The initial stages of water adsorption on magnetite Fe3O4(111) surface and the atomic structure of the water/oxide interface remain controversial. Herein, we provide experimental results obtained by infrared reflection-absorption spectroscopy (IRAS) and temperature programmed desorption (TPD), corroborated by density functional theory (DFT) calculations showing that water readily dissociates on Fetet sites to form two hydroxo species. These act as an anchor for water molecules to form a dimer complex which self-assembles into an ordered (2×2) structure...
December 4, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29190482/stropharia-rugosoannulata-and-gymnopilus-luteofolius-promising-fungal-species-for-pharmaceutical-biodegradation-in-contaminated-water
#8
Francesc Castellet-Rovira, Daniel Lucas, Marta Villagrasa, Sara Rodríguez-Mozaz, Damià Barceló, Montserrat Sarrà
Pharmaceuticals are environmental micropollutants that pose an emerging challenge because they are poorly eliminated in conventional wastewater treatment plants. Over the last decade, many attempts have been made to solve this problem, and wastewater fungal treatment is a promising alternative. In this study, six different ligninolytic fungi (Trametes versicolor, Ganoderma lucidum, Irpex lacteus, Stropharia rugosoannulata, Gymnopilus luteofolius and Agrocybe erebia) were studied as bioremediation candidates for the removal and degradation of six recalcitrant pharmaceutical micropollutants: Carbamazepine (CBZ), Venlafaxine (VFX), Iopromide (IPD), Diclofenac (DCF), Cyclophosphamide (CFD) and Ifosfamide (IFD)...
November 27, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29189407/effect-of-resistance-training-to-muscle-failure-versus-volitional-interruption-at-high-and-low-intensities-on-muscle-mass-and-strength
#9
Sanmy R Nóbrega, Carlos Ugrinowitsch, Lucas Pintanel, Cintia Barcelos, Cleiton A Libardi
The purpose of the present study was to investigate the effects of resistance training (RT) at high- and low-intensities performed to muscle failure or volitional interruption on muscle strength, cross-sectional area (CSA), pennation angle (PA) and muscle activation. Thirty-two untrained men participated in the study. Each leg was allocated in one of four unilateral RT protocols: RT to failure at high (HIRT-F) and low (LIRT-F) intensities, and RT to volitional interruption (repetitions performed to the point in which participants voluntarily interrupted the exercise) at high (HIRT-V) and low (LIRT-V) intensities...
January 24, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29177701/ultrasound-classification-of-traumatic-distal-biceps-brachii-tendon-injuries
#10
Javier de la Fuente, Marc Blasi, Sílvia Martínez, Pablo Barceló, Carlos Cachán, Maribel Miguel, Carles Pedret
OBJECTIVE: The present work is aimed at analysing ultrasound findings in patients with distal biceps brachii tendon (DBBT) injuries to assess the sensitivity of ultrasound in detecting the different forms of injury, and to compare ultrasound results with magnetic resonance imaging (MRI) and surgical results. MATERIALS AND METHODS: A total of 120 patients with traumatic DBBT injuries examined between 2011 and 2015 were analysed. We compared ultrasound results with MRI results when surgery was not indicated and with MRI and surgical results when surgery was indicated...
November 24, 2017: Skeletal Radiology
https://www.readbyqxmd.com/read/29177441/de-novo-mutations-in-caudal-type-homeo-box-transcription-factor-2-cdx2-in-patients-with-persistent-cloaca
#11
Jacob S J Hsu, Manting So, Clara S M Tang, Karim Anwarul, Robert M Porsch, Carol Wong, Michelle Yu, Fanny Yeung, Huimin Xia, Ruizhong Zhang, Stacey S Cherny, Patrick H Y Chung, K Y Wong Kenneth, Pak C Sham, Ngoc Diem Ngo, Miaoxin Li, Paul K H Tam, Vincent C H Lui, Maria-Mercè Garcia-Barcelo
The cloaca is an embryonic cavity that is divided into the urogenital sinus and rectum upon differentiation of the cloacal epithelium triggered by tissue-specific transcription factors including CDX2. Defective differentiation leads to persistent cloaca in humans (PC), a phenotype recapitulated in Cdx2 mutant mice. PC is linked to hypo/hyper-vitaminosis A. Although no gene has ever been identified, there is a strong evidence for a genetic contribution to PC. We applied whole-exome sequencing and copy-number-variants analyses to 21 PC patients and their unaffected parents...
November 21, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/29169098/assessing-the-effects-of-seawater-temperature-and-ph-on-the-bioaccumulation-of-emerging-chemical-contaminants-in-marine-bivalves
#12
Ana Luísa Maulvault, Carolina Camacho, Vera Barbosa, Ricardo Alves, Patrícia Anacleto, Fabiola Fogaça, Christiaan Kwadijk, Michiel Kotterman, Sara C Cunha, José O Fernandes, Rie R Rasmussen, Jens J Sloth, Òscar Aznar-Alemany, Ethel Eljarrat, Damià Barceló, António Marques
Emerging chemical contaminants [e.g. toxic metals speciation, flame retardants (FRs) and perfluorinated compounds (PFCs), among others], that have not been historically recognized as pollutants nor their toxicological hazards, are increasingly more present in the marine environment. Furthermore, the effects of environmental conditions (e.g. temperature and pH) on bioaccumulation and elimination mechanisms of these emerging contaminants in marine biota have been poorly studied until now. In this context, the aim of this study was to assess, for the first time, the effect of warmer seawater temperatures (Δ = + 4°C) and lower pH levels (Δ = - 0...
November 20, 2017: Environmental Research
https://www.readbyqxmd.com/read/29163935/the-cost-of-diabetes-in-latin-america-and-the-caribbean-in-2015-evidence-for-decision-and-policy-makers
#13
Alberto Barcelo, Armando Arredondo, Amparo Gordillo-Tobar, Johanna Segovia, Anthony Qiang
BACKGROUND: The financial implications of the increase in the prevalence of diabetes in middle-income countries represents one of the main challenges to health system financing and to the society as a whole. The objective of this study was to estimate the economic cost of diabetes in Latin America and the Caribbean (LAC) in 2015. METHODS: The study used a prevalence-based approach to estimate the direct and indirect costs related to diabetes in 29 LAC countries in 2015...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29160388/incremental-prognostic-value-of-the-incorporation-of-clinical-data-into-coronary-anatomy-data-in-acute-coronary-syndromes-syntax-grace-score
#14
Mateus Dos Santos Viana, Fernanda Lopes, Antonio Mauricio Dos Santos Cerqueira, Jessica Gonzalez Suerdieck, André Barcelos da Silva, Ana Clara Barcelos da Silva, Thiago Menezes Barbosa de Souza, Manuela Campelo Carvalhal, Marcia Maria Noya Rabelo, Luis Claudio Lemos Correia
BACKGROUND: When performing coronary angiography in patients with acute coronary syndrome (ACS), the anatomical extent of coronary disease usually prevails in the prognostic reasoning. It has not yet been proven if clinical data should be accounted for in risk stratification together with anatomical data. OBJECTIVE: To test the hypothesis that clinical data increment the prognostic value of anatomical data in patients with ACS. METHODS: Patients admitted with objective criteria for ACS and who underwent angiography during hospitalization were included...
November 13, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29154051/ecotoxicological-effects-of-carbon-based-nanomaterials-in-aquatic-organisms
#15
REVIEW
Anna Freixa, Vicenç Acuña, Josep Sanchís, Marinella Farré, Damià Barceló, Sergi Sabater
An increasing amount of carbon-based nanomaterials (CNM) (mostly fullerenes, carbon nanotubes and graphene) has been observed in aquatic systems over the last years. However, the potential toxicity of these CNM on aquatic ecosystems remains unclear. This paper reviews the existing literature on the toxic effects of CNM in aquatic organisms as well as the toxic effects of CNM through influencing the toxicity of other micro-pollutants, and outlines a series of research needs to reduce the uncertainty associated with CNMs toxic effects...
November 15, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29153671/longitudinal-evaluation-of-uterine-perfusion-endothelial-function-and-central-blood-flow-in-early-onset-pre-eclampsia
#16
Ludmila Barcelos Porto, Augusto Henriques Fulgêncio Brandão, Henrique Vítor Leite, Antônio Carlos Vieira Cabral
OBJECTIVES: Physiopathological mechanisms that trigger clinical manifestations in pre-eclampsia (PE) remain unclear, and management is still a challenge. The identification of tools to predict the onset of the disease and prevent its complications is of great interest in medical practice. The present study aims to evaluate uterine perfusion, endothelial function and central nervous system blood flow in pregnant women with high-risk factors for PE, for comparison of the results between the group of patients who developed early onset PE and those who remained normotensive throughout pregnancy...
October 2017: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29150113/dna-microarray-expression-profiling-of-a-new-t-8-13-aml-case-allows-identification-of-possible-leukemogenic-transformation-markers
#17
Aline Rangel Pozzo, Fernanda Costas Casal de Faria, Luize Otero de Carvalho, Marcos Barcelos de Pinho, Raquel Ciuvalschi Maia
No abstract text is available yet for this article.
October 2017: Revista Brasileira de Hematologia e Hemoterapia
https://www.readbyqxmd.com/read/29136596/occurrence-of-organic-uv-filters-and-metabolites-in-lebranche-mullet-mugil-liza-from-brazil
#18
Daniel Molins-Delgado, Ramón Muñoz, Sylvia Nogueira, Mariana B Alonso, João Paulo Torres, Olaf Malm, Roberta Lourenço Ziolli, Rachel Ann Hauser-Davis, Ethel Eljarrat, Damià Barceló, M Silvia Díaz-Cruz
UV filters (UV-Fs) constitute a heterogeneous group of chemicals used as protection against the effects of UV radiation, widely used in all sort of goods and ubiquitous in the environment. The presence of these chemicals in fish is a matter of concern, because many UV-Fs display hormonal activity. In this study, muscle, gills, and liver from 11 Mugil liza individuals from the highly urbanized Guanabara Bay (Rio de Janeiro, Brazil) were analysed in order to detect eight UV-Fs and metabolites (4-dihydroxybenzophenone [BP1] (2-hydroxy-4-methoxybenzophenone [BP3], 4-methylbenzylidiene camphor [4MBC], ethylhexyl methoxycinnamate [EHMC], ethylhexyl dimethyl p-aminobenzoic acid [ODPABA], octocrylene [OC], 4-hydroxybenzophenone [4HB], and 4,4'-dihydroxybenzophenone [4DHB]) using liquid chromatography-tandem mass spectrometry (HPLC-MS/MS)...
November 11, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29132933/long-term-follow-up-of-the-advance%C3%A2-advancexp%C3%A2-sling-what-are-the-surgeons-impressions-what-are-the-patients
#19
A Romero Hoyuela, L Reina Alcaina, E Izquierdo Morejon, A Rosino Sanchez, C Carrillo George, A Rivero Guerra, I Barcelo Bayonas, A Pardo Martinez, V Muñoz Guillermo, B Pietricica, T Fernandez Aparicio, G Hita Villaplana, B Miñana Lopez
OBJECTIVES: To analyse the safety, efficacy and quality of life of patients with male stress urinary incontinence after radical prostatectomy treated with the AdVance® and AdvanceXP® slings. PATIENTS AND METHOD: The study included 92 patients with stress urinary incontinence after radical prostatectomy treated with the AdVance® and AdVanceXP® sling between May 2008 and December 2015. A perineal repositioning test was performed in all cases with sphincter coaptation of≥1...
November 10, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/29132141/shoulder-giant-schwannoma-a-diagnosis-to-be-considered-in-painless-shoulder-masses
#20
Romeu Pinho, Sara Santana, Filipa Farinha, Inês Cunha, Anabela Barcelos, José Brenha
Tumours formed from peripheral nerve sheaths are rare in the shoulder. We present the case of a 80-year-old female referred to an orthopaedic surgery clinic because of a large painless mass of the right shoulder, with one year of evolution. There was no history of trauma, involvement of any other joint or systemic complaints. Given the clinical and imagiological suspicion of a giant synovial cyst, the patient underwent complete surgical resection of the mass, which took place without any complications or functional impairment...
November 5, 2017: Acta Reumatológica Portuguesa
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