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https://www.readbyqxmd.com/read/27904911/effect-of-bihemispheric-anodal-transcranial-direct-current-stimulation-for-dysphagia-in-chronic-stroke-patients-a-randomized-clinical-trial
#1
Young Hyun Ahn, Hyun-Joo Sohn, Jin-Sung Park, Tae Gyu Ahn, Yong Beom Shin, Minsu Park, Sung-Hwa Ko, Yong-Il Shin
OBJECTIVE: To investigate whether bihemispheric anodal transcranial direct current stimulation (tDCS) with conventional dysphagia therapy could improve swallowing function in chronic stroke patients with dysphagia. DESIGN: Randomized controlled trial. SUBJECTS: Twenty-six patients with dysphagia for at least 6 months post-stroke were randomly assigned into: (i) bihemispheric anodal tDCS group; or (ii) sham group. METHODS: All patients underwent 10 tDCS sessions with simultaneous conventional swallowing therapy for 2 weeks...
November 30, 2016: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/27898173/an-update-on-larynx-cancer
#2
REVIEW
Conor E Steuer, Mark El-Deiry, Jason R Parks, Kristin A Higgins, Nabil F Saba
Answer questions and earn CME/CNE Laryngeal cancer remains one of the most common tumors of the respiratory tract. Fortunately, significant advancements have been made over the past decade in the treatment of laryngeal cancer. Although surgery has been the historical mainstay for localized disease and still is an integral part of treatment, nonsurgical options like radiation and systemic therapy have emerged as viable options. In addition, in the metastatic setting, novel agents are showing promise for this patient population...
November 29, 2016: CA: a Cancer Journal for Clinicians
https://www.readbyqxmd.com/read/27890349/clinical-features-and-outcomes-of-20-patients-with-abdominopelvic-desmoplastic-small-round-cell-tumor
#3
F A Angarita, S Hassan, A J Cannell, B C Dickson, R A Gladdy, C J Swallow, A Gupta, M E Blackstein, J A McCart
INTRODUCTION: Desmoplastic small round cell tumor (DSRCT) is a rare mesenchymal malignancy. We describe our experience with treating DSRCT at a large sarcoma referral center. METHODS: A retrospective chart review was performed on DSRCT patients referred to our institution (1998-2014). Pathology specimens were reviewed to confirm the diagnosis. Clinical and imaging were extracted and summarized with descriptive statistics. Univariate analysis was performed to evaluate the association between patient, tumor, and treatment variables and overall survival (OS)...
October 4, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27883209/tongue-to-palate-resistance-training-improves-tongue-strength-and-oropharyngeal-swallowing-function-in-subacute-stroke-survivors-withdysphagia
#4
H D Kim, J B Choi, S J Yoo, M Y Chang, S W Lee, J S Park
Tongue function can affect both the oral and pharyngeal stages of the swallowing process, and proper tongue strength are vital for safe oropharyngeal swallowing. This trial investigated the effect of tongue to palate resistance training (TPRT) on tongue strength and oropharyngeal swallowing function in stroke with dysphagia patients. This trial was performed using a 4-week, 2-group, pre-post design. Participants were allocated to the experimental group (n=18) or the control group (n=17). The experimental group was performed TPRT for 4 wks/, 5 day/wk) and traditional dysphagia therapy, whereas the control group performed traditional dysphagia therapy on the same schedule...
November 24, 2016: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/27863592/nursing-interventions-in-stroke-care-delivery-an-evidence-based-clinical-review
#5
Dimitrios Theofanidis, Bernard Gibbon
INTRODUCTION: Generally, nursing interventions during the acute stages following a stroke aim at preventing secondary brain injury (intracranial hypertension), maintaining the airways (due to paralysis of the pharynx muscles), providing general body support (vital signs, fluid and electrolyte balance), and anticipating the occurrence of complications (atelectasis and pneumonia). AIM: This literature review is to prioritize nursing interventions for acute stroke and to update nursing roles and input considering recommended levels of evidence of care to date...
December 2016: Journal of Vascular Nursing: Official Publication of the Society for Peripheral Vascular Nursing
https://www.readbyqxmd.com/read/27861932/residue-influences-quality-of-life-independently-of-penetration-and-aspiration-in-head-and-neck-cancer-survivors
#6
Tanya K Meyer, Jessica M Pisegna, Gintas P Krisciunas, Barbara R Pauloski, Susan E Langmore
OBJECTIVES/HYPOTHESIS: Dysphagia is one of the most significant side effects of the treatment of head and neck cancer. Residue and aspiration are two indicators of dysphagia, but aspiration is historically the only indicator of interest, because it may impact health outcomes. Clinicians have anecdotally used residue as another marker of swallowing dysfunction, but it is understudied. This project investigated the impact of aspiration versus residue on function and quality of life (QoL) in these patients...
November 9, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27859412/oesophageal-lichen-planus-the-efficacy-of-topical-steroid-based-therapies
#7
A Podboy, D Sunjaya, T C Smyrk, J A Murray, M Binder, D A Katzka, J A Alexander, M Halland
BACKGROUND: Oesophageal lichen planus is an idiopathic inflammatory disorder characterized by significant oesophageal stricturing. Oesophageal lichen planus is a rare, difficult to diagnose, and likely an under recognized disease. As a result, there is no standardized approach to therapy and treatment strategies vary. AIM: To examine the utility of topical steroid therapy (fluticasone or budesonide) in the management of oesophageal lichen planus. METHODS: A retrospective chart review was conducted of patients diagnosed with oesophageal lichen planus who underwent baseline and follow up endoscopy pre and post topical steroid therapy between 1995 and 2016 at Mayo Clinic, Rochester MN...
November 17, 2016: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27859286/effects-of-electrical-stimulation-on-vocal-functions-in-patients-with-nasopharyngeal-carcinoma
#8
Thomas Law, Kathy Y-S Lee, Rita W-M Wong, Yeptain Leung, Peter K-M Ku, Eddy W-Y Wong, Hok-Nam Li, Louisa K-Y Ng, C Andrew van Hasselt, Michael C-F Tong
OBJECTIVES/HYPOTHESIS: This study aimed to evaluate the effects of neuromuscular electrical stimulation (NMES) on vocal functions in patients with nasopharyngeal carcinoma following radiation therapy. STUDY DESIGN: Prospective, randomized controlled trial. METHODS: One hundred forty newly treated NPC patients were recruited and randomized into NMES or traditional swallowing exercise (TE) group. Participants received intensive NMES or traditional swallowing therapy and were followed up until 12 months postrandomization...
November 12, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27859013/needle-tract-seeding-after-percutaneous-biopsy-of-sarcoma-risk-benefit-considerations
#9
REVIEW
David Berger-Richardson, Carol J Swallow
To evaluate histologic subtype and grade, which in turn guide the decision making for multimodality therapy, the workup of suspected sarcoma requires more material than can be obtained from a fine-needle aspiration. Either open or percutaneous core needle biopsy is indicated before a management decision is made. Percutaneous biopsy of a potentially malignant lesion is controversial, given the perceived potential for tumor seeding along the needle tract. However, the evidence that the latter is a significant risk is weak at best...
November 2, 2016: Cancer
https://www.readbyqxmd.com/read/27857262/role-of-gabapentin-in-managing-mucositis-pain-in-patients-undergoing-radiation-therapy-to-the-head-and-neck
#10
Carol Ann Milazzo-Kiedaisch, Joanne Itano, Pinaki R Dutta
BACKGROUND: Oral mucositis (OM) is a painful and debilitating side effect that affects 80%-100% of patients undergoing radiation therapy for head and neck cancer. This dose-limiting side effect may potentially lead to pain, dehydration, malnutrition, infection, and treatment breaks. Treatment breaks can lead to decreased disease control and suboptimal patient outcomes. No primary prevention exists for OM, and management is focused on pain control. Compelling evidence exists that OM pain has somatic and neuropathic components...
December 1, 2016: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/27853984/fentanyl-pectin-nasal-spray-for-painful-mucositis-in-head-and-neck-cancers-during-intensity-modulated-radiation-therapy-with-or-without-chemotherapy
#11
R Mazzola, F Ricchetti, A Fiorentino, N Giaj-Levra, S Fersino, U Tebano, S Albanese, S Gori, F Alongi
PURPOSE: The aim of the current analysis was to evaluate the effectiveness and tolerability of rapid onset opioid in a cohort of head and neck cancer (HNC) patients affected by painful mucositis influencing swallowing function during RT ± ChT with definitive or adjuvant intent. METHODS: A retrospective analysis was conduct on HNC patients during RT ± ChT that received fentanyl pectin na sal spray (FPNS) for incidental BTP due to painful mucositis 13 min before the main meals...
November 16, 2016: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/27848021/impact-of-compliance-on-dysphagia-rehabilitation-in-head-and-neck-cancer-patients-results-from-a-multi-center-clinical-trial
#12
Gintas P Krisciunas, Kerlly Castellano, Timothy M McCulloch, Cathy L Lazarus, Barbara R Pauloski, Tanya K Meyer, Darlene Graner, Douglas J Van Daele, Alice K Silbergleit, Lisa R Crujido, Denis Rybin, Gheorghe Doros, Tamar Kotz, Susan E Langmore
A 5-year, 16-site, randomized controlled trial enrolled 170 HNC survivors into active (estim + swallow exercise) or control (sham estim + swallowing exercise) arms. Primary analyses showed that estim did not enhance swallowing exercises. This secondary analysis determined if/how patient compliance impacted outcomes. A home program, performed 2 times/day, 6 days/week, for 12 weeks included stretches and 60 swallows paired with real or sham estim. Regular clinic visits ensured proper exercise execution, and detailed therapy checklists tracked patient compliance which was defined by mean number of sessions performed per week (0-12 times) over the 12-week intervention period...
November 16, 2016: Dysphagia
https://www.readbyqxmd.com/read/27846899/contribution-of-submandibular-gland-and-swallowing-structure-sparing-to-post-radiation-therapy-peg-dependence-in-oropharynx-cancer-patients-treated-with-split-neck-imrt-technique
#13
Michael F Gensheimer, Matthew Nyflot, George E Laramore, Jay J Liao, Upendra Parvathaneni
BACKGROUND: Radiation therapy-related dysphagia is worsened by xerostomia. The submandibular glands (SMG) produce saliva rich in lubricating mucins, and sparing the SMG has been shown to reduce xerostomia. The goal of this study was to determine whether SMG sparing IMRT is associated with reduced post-treatment PEG dependence in locally advanced oropharynx cancer patients. METHODS: Patients treated with definitive radiation therapy for oropharynx cancer were included in this retrospective study...
November 15, 2016: Radiation Oncology
https://www.readbyqxmd.com/read/27844152/adherence-to-a-prophylactic-swallowing-therapy-program-during-chemo-radiotherapy-impact-of-service-delivery-model-and-patient-factors
#14
Laurelie R Wall, Elizabeth C Ward, Bena Cartmill, Anne J Hill, Sandro V Porceddu
Intensive, prophylactic swallowing therapy programs have been developed to improve dysphagia outcomes for patients with head/neck cancer (HNC) receiving (chemo)radiotherapy ([C]RT). Across studies, variable therapy adherence rates have been reported. Preliminary research suggests that service-delivery mode and demographic factors may influence adherence. This study examined patient adherence to a prophylactic swallowing therapy protocol across three service-delivery models: (1) clinician-directed face-to-face therapy, (2) technology-assisted therapy using the telepractice application, SwallowIT and (3) independent patient-directed therapy...
November 14, 2016: Dysphagia
https://www.readbyqxmd.com/read/27843470/childhood-neurogenic-stuttering-due-to-bilateral-congenital-abnormality-in-globus-pallidus-a-case-report-and-review-of-the-literature
#15
Mohammad Javad Saeedi, Ebrahim Esfandiary, Mostafa Almasi Dooghaee
Objective The basal ganglia are a group of structures that act as a cohesive functional unit. They are situated at the base of the forebrain and are strongly connected with the cerebral cortex and thalamus. Some speech disorders such as stuttering can resulted from disturbances in the circuits between the basal ganglia and the language motor area of the cerebral cortex. Stuttering consists of blocks, repetitive, prolongation or cessation of speech. We present a 7.5 -year-old male child with bilateral basal ganglia lesion in globus pallidus with unclear reason...
2016: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/27818585/update-on-the-endoscopic-treatments-for-achalasia
#16
REVIEW
Dushant S Uppal, Andrew Y Wang
Achalasia is the most common primary motility disorder of the esophagus and presents as dysphagia to solids and liquids. It is characterized by impaired deglutitive relaxation of the lower esophageal sphincter. High-resolution manometry allows for definitive diagnosis and classification of achalasia, with type II being the most responsive to therapy. Since no cure for achalasia exists, early diagnosis and treatment of the disease is critical to prevent end-stage disease. The central tenant of diagnosis is to first rule out mechanical obstruction due to stricture or malignancy, which is often accomplished by endoscopic and fluoroscopic examination...
October 21, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27812787/prophylactic-exercises-among-head-and-neck-cancer-patients-during-and-after-swallowing-sparing-intensity-modulated-radiation-adherence-and-exercise-performance-levels-of-a-12-week-guided-home-based-program
#17
Ingrid C Cnossen, Cornelia F van Uden-Kraan, Birgit I Witte, Yke J Aalders, Cees J T de Goede, Remco de Bree, Patricia Doornaert, Derek H F Rietveld, Jan Buter, Johannes A Langendijk, C René Leemans, Irma M Verdonck-de Leeuw
The background and purpose of this paper is to investigate adherence, exercise performance levels and associated factors in head and neck cancer (HNC) patients participating in a guided home-based prophylactic exercise program during and after treatment [swallowing sparing intensity modulated radiation therapy (SW-IMRT)]. Fifty patients were included in the study. Adherence was defined as the percentage of patients who kept up exercising; exercise performance level was categorized as low: ≤1, moderate: 1-2, and high: ≥2 time(s) per day, on average...
November 3, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27798948/optimizing-outcomes-following-total-and-subtotal-tongue-reconstruction-a-systematic-review-of-the-contemporary-literature
#18
Oscar J Manrique, Hyuma A Leland, Claude-Jean Langevin, Alex Wong, Joseph N Carey, Pedro Ciudad, Hung-Chi Chen, Ketan M Patel
BACKGROUND: More than 45,000 Americans are diagnosed with oropharyngeal cancer annually and multimodal treatment often requires wide excision, lymphadenectomy, chemotherapy, and radiation. Total and subtotal lingual resection severely impairs speech, swallow, and quality of life (QoL). This study investigates functional outcomes and QoL following subtotal and total tongue resection with free tissue transfer reconstruction. MATERIALS AND METHODS: A systematic review of the English language literature was performed using PubMed, Ovid, Embase, and Cochrane databases based on predetermined inclusion/exclusion criteria...
October 31, 2016: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/27796777/impact-of-adherence-to-antiemetic-guidelines-on-the-incidence-of-chemotherapy-induced-nausea-and-vomiting-and-quality-of-life
#19
Nibal Abunahlah, Mesut Sancar, Faysal Dane, Mustafa Kerem Özyavuz
Background International guidelines are tools enabling physicians to incorporate the latest evidence based clinical information into practice. Objective This study aimed to evaluate the impact of antiemetic guidelines adherence on the incidence of chemotherapy-induced nausea and vomiting (CINV) and patient quality of life. Setting Marmara University Pendik Training and Research Hospital chemotherapy unit, Istanbul, Turkey. Method The study included 100 chemotherapy naive patients. Antiemetic prescribing patterns and their consistency with MASCC/ESMO 2014 guidelines were assessed...
December 2016: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/27795799/-thyroid-abscess-revealing-graves-basedow-disease-about-a-case-and-review-of-the-literature
#20
Meriem Chenguir, Hajar Souldi, Fatima Zahra Loufad, Sami Rouadi, Reda Abada, Mohamed Roubal, Mohamed Mahtar
Thyroid abscess is a very rare clinical entity. It accounts for 0.1% of the surgical pathologies of the thyroid gland. The anatomical and physiological characteristics of the gland give it resistance to pathogens. Streptococcal and Staphylococcal are the most common. Tuberculosis is rarely reported in the literature. The occurrence of infection associated with toxic goiter is exceptional. The authors report a rare case of a 22-year-old young patient with thyroid abscess revealing a toxic goitre. He presented to our otorhinolaryngology emergency unit with anterior cervical swelling, slightly lateralized to the left, moving on swallowing, associated with hemoptysis, signs of thyroid dysfunction, fever, night sweats...
2016: Pan African Medical Journal
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