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Prostate Health Index

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https://www.readbyqxmd.com/read/29779925/the-application-of-p2psa-and-prostate-health-index-in-prostate-cancer-detection-a-prospective-cohort-in-a-tertiary-medical-center
#1
Yung-Ting Cheng, Chih-Hung Chiang, Yeong-Shiau Pu, Shih Ping Liu, Yu-Chuang Lu, Yi-Kai Chang, Hong-Chiang Chang, Kuo-How Huang, Yuan-Ju Lee, Po-Ming Chow, Shih-Chun Hung, Chao-Yuan Huang
BACKGROUND/PURPOSE: Prostate specific antigen (PSA) with low specificity that causes unnecessary prostate biopsies increases clinical morbidities, psychological stress, and medical expenses. We aimed to test the accuracy and cutoff value of Prostate Health Index (PHI) in men for prostate cancer detection. METHODS: We prospectively enrolled 213 men who underwent prostate biopsy with PSA≦10 ng/ml or abnormal findings on digital rectal examination. Total PSA (tPSA), free PSA (fPSA) and p2PSA levels were measured by serum samples before prostate biopsy...
May 17, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/29779672/modifiable-risk-factors-to-reduce-renal-cell-carcinoma-incidence-insight-from-the-plco-trial
#2
Jonathan Gelfond, Osamah Al-Bayati, Aashish Kabra, Kevan Iffrig, Dharam Kaushik, Michael A Liss
INTRODUCTION: Identify modifiable factors contributing to renal cell carcinoma in the PCLO to target disease prevention and reduce health care costs. METHODS: The prostate, lung, colorectal, and ovarian database were queried for the primary outcome of kidney cancer. Demographics were investigated, specifically focusing on modifiable risk factors. Statistical analysis includes the Student t-test for continuous variables, chi-squared or Fisher's exact tests for dichotomous and categorical variables for bivariate analysis...
May 17, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29757454/non-pharmacological-interventions-for-treating-chronic-prostatitis-chronic-pelvic-pain-syndrome
#3
REVIEW
Juan Va Franco, Tarek Turk, Jae Hung Jung, Yu-Tian Xiao, Stanislav Iakhno, Virginia Garrote, Valeria Vietto
BACKGROUND: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disorder in which the two main clinical features are pelvic pain and lower urinary tract symptoms. There are currently many approaches for its management, using both pharmacological and non-pharmacological interventions. The National Institute of Health - Chronic Prostatitis Symptom Index (NIH-CPSI) score is a validated measure commonly used to measure CP/CPPS symptoms. OBJECTIVES: To assess the effects of non-pharmacological therapies for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)...
May 12, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29744476/prostate-calcifications-a-case-series-supporting-the-microbial-biofilm-theory
#4
Tommaso Cai, Francesco Tessarolo, Iole Caola, Federico Piccoli, Giandomenico Nollo, Patrizio Caciagli, Sandra Mazzoli, Alessandro Palmieri, Paolo Verze, Gianni Malossini, Vincenzo Mirone, Truls E Bjerklund Johansen
Purpose: Prostate calcifications are a common finding during transrectal prostate ultrasound in both healthy subjects and patients, but their etiopathogenesis and clinical significance are not fully understood. We aimed to establish a new methodology for evaluating the role of microbial biofilms in the genesis of prostate calcifications. Materials and Methods: Ten consecutive patients who had undergone radical prostatectomy were enrolled in this study. All of the patients presented with prostate calcifications during transrectal ultrasound evaluation before surgery and underwent Meares-Stamey tests and clinical evaluation with the National Institutes of Health Chronic Prostatitis Symptom Index and the International Prostate Symptom Score...
May 2018: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/29743218/living-in-cold-spot-communities-is-associated-with-poor-health-and-health-quality
#5
Winston Liaw, Alex H Krist, Sebastian T Tong, Roy Sabo, Camille Hochheimer, Jennifer Rankin, David Grolling, Jene Grandmont, Andrew W Bazemore
PURPOSE: Little is known about incorporating community data into clinical care. This study sought to understand the clinical associations of cold spots (census tracts with worse income, education, and composite deprivation). METHODS: Across 12 practices, we assessed the relationship between cold spots and clinical outcomes (obesity, uncontrolled diabetes, pneumonia vaccination, cancer screening-colon, cervical, and prostate-and aspirin chemoprophylaxis) for 152,962 patients...
May 2018: Journal of the American Board of Family Medicine: JABFM
https://www.readbyqxmd.com/read/29739772/associations-of-grip-strength-with-cardiovascular-respiratory-and-cancer-outcomes-and-all-cause-mortality-prospective-cohort-study-of-half-a-million-uk-biobank-participants
#6
Carlos A Celis-Morales, Paul Welsh, Donald M Lyall, Lewis Steell, Fanny Petermann, Jana Anderson, Stamatina Iliodromiti, Anne Sillars, Nicholas Graham, Daniel F Mackay, Jill P Pell, Jason M R Gill, Naveed Sattar, Stuart R Gray
OBJECTIVE: To investigate the association of grip strength with disease specific incidence and mortality and whether grip strength enhances the prediction ability of an established office based risk score. DESIGN: Prospective population based study. SETTING: UK Biobank. PARTICIPANTS: 502 293 participants (54% women) aged 40-69 years. MAIN OUTCOME MEASURES: All cause mortality as well as incidence of and mortality from cardiovascular disease, respiratory disease, chronic obstructive pulmonary disease, and cancer (all cancer, colorectal, lung, breast, and prostate)...
May 8, 2018: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/29738183/-efficacy-of-lamiophlomis-rotata-capsule-in-the-treatment-of-type-%C3%A2-b-prostatitis
#7
Zhi-Feng Wei, Kai Zhou, Jie Dong, Dian Fu, Xiao-Feng Xu, Ping Li, Wen Cheng, Zheng-Yu Zhang
Objective: To study the therapeutic effect of Lamiophlomis Rotata Capsule (LRC) in the treatment of type ⅢB prostatitis. METHODS: We randomly divided 225 patients with type ⅢB prostatitis into an experimental group (n =125) and a control group (n =120), the former treated orally with LRC at 3 capsules tid while the latter with tamsulosin hydrochloride sustained-release capsules at 0.2 mg qd, both for 4 weeks. We compared the therapeutic effects between the two groups of patients based on the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) obtained before, immediately after and at 4 weeks after medication...
December 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29735367/sleep-disturbance-has-a-higher-impact-on-general-and-mental-quality-of-life-reduction-than-nocturia-results-from-the-community-health-survey-in-japan
#8
Koichi Kido, Shingo Hatakeyama, Atsushi Imai, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Shigeyuki Nakaji, Chikara Ohyama
BACKGROUND: Nocturia has been reported to be associated with sleep disturbance. However, whether nocturia or sleep disturbance has a more negative influence on the quality of life (QOL) of individuals remains unclear. OBJECTIVE: To compare the impact of nocturia and sleep disturbance on QOL. DESIGN, SETTING, AND PARTICIPANTS: This was a cross-sectional study including 3992 adults who participated in the Iwaki Health Promotion Project between 2011 and 2015 in Hirosaki, Japan...
May 4, 2018: European Urology Focus
https://www.readbyqxmd.com/read/29733836/acupuncture-for-chronic-prostatitis-chronic-pelvic-pain-syndrome-a-randomized-sham-acupuncture-controlled-trial
#9
Zongshi Qin, Zhiwei Zang, Kehua Zhou, Jiani Wu, Jing Zhou, Joey S W Kwong, Zhishun Liu
PURPOSE: To investigate the effectiveness of acupuncture for patients with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). MATERIALS AND METHODS: We conducted this 32-week (8 weeks of treatment followed by 24 weeks of follow-up) randomized controlled trial comparing acupuncture with sham acupuncture. Participants with CP/CPPS were randomly assigned to acupuncture or non-invasive sham acupuncture. The primary outcome was the change in the National Institutes of Health Chronic Prostatitis Symptom Index (NIH-CPSI) total score from baseline to week 8...
May 4, 2018: Journal of Urology
https://www.readbyqxmd.com/read/29732206/patient-experience-after-transperineal-template-prostate-biopsy-compared-to-prior-transrectal-ultrasound-guided-prostate-biopsy
#10
Nikita R Bhatt, Kieran Breen, Usman M Haroon, Muhammad Akram, Hugh D Flood, Subhasis K Giri
Introduction: Transperineal template prostate biopsy (TTPB) is reported to have higher cancer detection and lower complication rate compared to transrectal ultrasound guided prostate biopsy (TRUSPB).However, there is no report of the same patient's experience with both types of biopsy.To compare the patient reported experience in the same cohort of patients who underwent both TRUSPB and TTPB, using validated questionnaires. Material and methods: We retrospectively utilised the Patient Reported Outcome Methods (PROM) tool validated for TRUSPB and the International Index of Erectile Function (IIEF-5) questionnaire to collect longitudinal data at follow-up in the same cohort of patients who underwent both TTPB and TRUSPB between January 2015 and February 2016...
2018: Central European Journal of Urology
https://www.readbyqxmd.com/read/29703064/acupuncture-for-chronic-prostatitis-a-systematic-review-and-meta-analysis-protocol
#11
Tianzhong Peng, Ying Cheng, Yuhao Jin, Na Xu, Taipin Guo
BACKGROUND: Chronic prostatitis (CP) is a prevalent genitourinary condition. Considering its safety profile, acupuncture can be an option treating CP symptoms. The aim of this review is to undertake a systematic review to estimate the effectiveness and safety of acupuncture on CP. METHODS: We will search all randomized controlled trials for CP in August 2018 in the databases of MEDLINE, Cochrane Library, Web of Science, EMBASE, Springer, WHO International Clinical Trials Registry Platform (ICTRP), China National Knowledge Infrastructure (CNKI), Wan fang, Chinese Biomedical Literature Database (CBM), PsycInfo, Chinese Scientific Journal Database (VIP), and other available resources...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29698941/computer-assisted-quantitative-assessment-of-prostatic-calcifications-in-patients-with-chronic-prostatitis
#12
Matteo Boltri, Vittorio Magri, Emanuele Montanari, Gianpaolo Perletti, Alberto Trinchieri
BACKGROUND: The aim of this study was the development of quantitative assessment of prostatic calcifications at prostatic ultrasound examination by the use of an image analyzer. MATERIALS AND METHODS: A group of 82 patients was evaluated by medical history, physical, and transrectal ultrasound examination. Patients had a urethral swab, a 4-specimen study and culture of the seminal fluid. Patients were classified according to National Institute of Diabetes and Digestive and Kidney Diseases/National Institutes of Health...
April 26, 2018: Urologia Internationalis
https://www.readbyqxmd.com/read/29696814/difference-in-prostate-cancer-incidence-around-sixty-years-effects-of-age-and-metabolic-diseases
#13
Jin Bong Choi, Jung Ho Kim, Sung-Hoo Hong, Kyung-Do Han, U-Syn Ha
We examined the risk of prostate cancer in the Korean population stratified on the basis of age group and risk based on metabolic diseases, using National Health Insurance System (NHIS) data. Of the 51,827,813 people from the NHIS data in 2015, 10,879,591 men without prostate cancer who underwent a health examination were analyzed. The risk of prostate cancer was analyzed with stratification by age. Multivariate-adjusted Cox regression analysis was conducted to examine the association between prostate cancer and metabolic diseases by age groups...
April 25, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29686597/new-bacterial-infection-in-the-prostate-after-transrectal-prostate-biopsy
#14
Yumi Seo, Gilho Lee
Background: The prostate is prone to infections. Hypothetically, bacteria can be inoculated into the prostate during a transrectal prostate biopsy (TRPB) and progress into chronic bacterial prostatitis. Therefore, we examined new bacterial infections in biopsied prostates after TRPB and whether they affect clinical characteristics in the biopsied patients. Methods: Of men whose prostate cultures have been taken prior to TRPB, 105 men with bacteria-free benign prostate pathology underwent an additional repeated prostate culture within a year after TRPB...
April 23, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29680006/treatment-of-refractory-category-iii-nonbacterial-chronic-prostatitis-chronic-pelvic-pain-syndrome-with-intraprostatic-injection-of-onabotulinumtoxina-a-prospective-controlled-study
#15
Taha A Abdel-Meguid, Hisham A Mosli, Hasan Farsi, Ahmad Alsayyad, Abdulmalik Tayib, Moataz Sait, Ahmad Abdelsalam
INTRODUCTION: To evaluate the efficacy and safety of intraprostatic injections of onabotulinumtoxinA (onaBoNT-A) to treat refractory chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). MATERIALS AND METHODS: Prospective two-group controlled study. Treatment group included adult men with refractory category-III nonbacterial CP/CPPS who underwent transurethral intraprostatic injections of onaBoNT-A (200 U). Control group included comparable patients who underwent cystoscopy only...
April 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29660795/symptom-and-function-profiles-of-men-with-localized-prostate-cancer
#16
Bryce B Reeve, Xianming Tan, Ronald C Chen, Deborah S Usinger, Laura C Pinheiro
BACKGROUND: Men diagnosed with localized prostate cancer seek information on how treatment options may impact their health-related quality of life (HRQOL). The authors used latent profile analysis (LPA) to group men according to their symptom burden and functional status and to identify patient characteristics associated with each HRQOL profile. METHODS: Patients completed the Patient-Reported Outcomes Measurement Information System and the Expanded Prostate Index Composite measures 3 months after treatment initiation...
April 16, 2018: Cancer
https://www.readbyqxmd.com/read/29606553/new-and-emerging-technologies-in-treatment-of-lower-urinary-tract-symptoms-from-benign-prostatic-hyperplasia
#17
REVIEW
Nikhil K Gupta, Steven N Gange, Kevin T McVary
INTRODUCTION: Lower urinary tract symptoms (LUTS) from bladder outlet obstruction from benign prostatic hyperplasia (BPH) occur in a large percentage of urologic patients. Treatment of this condition with medical and surgical therapy provides symptom relief but has serious adverse effects and causes sexual dysfunction. New technologies to treat BPH-associated LUTS aim to effectively treat urinary symptoms and minimize side effects and sexual dysfunction. AIM: To review the efficacy of new and emerging therapies for treatment of LUTS from BPH...
March 29, 2018: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/29603553/health-related-quality-of-life-in-active-surveillance-and-radical-prostatectomy-for-low-risk-prostate-cancer-a-prospective-observational-study-harow
#18
Lena Ansmann, Nicola Winter, Nicole Ernstmann, Axel Heidenreich, Lothar Weissbach, Jan Herden
OBJECTIVES: To compare Health-related Quality of Life (HRQOL) between patients with localized Prostate Cancer (PCa) in the active surveillance (AS) group and the radical prostatectomy (RP) group, since evidence shows that both groups have similar oncological outcomes. Thus, comparative findings on the patients' HRQOL are becoming even more important to allow for informed treatment decision-making. PATIENTS AND METHODS: HAROW (Hormonal therapy, Active Surveillance, Radiation, Operation, Watchful Waiting) is a prospective, observational study designed to collect data for different treatment options for newly diagnosed patients with localised prostate cancer under real-life conditions...
March 30, 2018: BJU International
https://www.readbyqxmd.com/read/29594551/pair-matched-patient-reported-quality-of-life-and-early-oncological-control-following-focal-irreversible-electroporation-versus-robot-assisted-radical-prostatectomy
#19
Matthijs J Scheltema, John I Chang, Maret Böhm, Willemien van den Bos, Alexandar Blazevski, Ilan Gielchinsky, Anton M F Kalsbeek, Pim J van Leeuwen, Tuan V Nguyen, Theo M de Reijke, Amila R Siriwardana, James E Thompson, Jean J de la Rosette, Phillip D Stricker
PURPOSE: The design, conduct and completion of randomized trials for curative prostate cancer (PCa) treatments are challenging. To evaluate the effect of robot-assisted radical prostatectomy (RARP) versus focal irreversible electroporation (IRE) on patient-reported quality of life (QoL) and early oncological control using propensity-scored matching. METHODS: Patients with T1c-cT2b significant PCa (high-volume ISUP 1 or any 2/3) who received unifocal IRE were pair-matched to patients who received nerve-sparing RARP...
March 28, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29566837/economic-evaluation-of-treating-skeletal-related-events-among-prostate-cancer-patients
#20
Yue Zhong, Adriana Valderrama, Jianying Yao, Prina Donga, Pinar Bilir, Peter J Neumann
OBJECTIVES: To evaluate the economic burden of treating skeletal-related events (SREs) in prostate cancer (PC) patients with bone metastasis from an insurer perspective. METHODS: We conducted a retrospective cohort analysis using claims data. PC patients with bone metastasis were identified in the MarketScan Databases between January 1, 2004, and March 1, 2014. The propensity score matching approach was used to match patients with SREs to those without SREs. A pseudo-SRE date was assigned to the control group...
March 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
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