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Prostate Health Index

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https://www.readbyqxmd.com/read/28926645/alterations-in-regional-homogeneity-of-resting-state-cerebral-activity-in-patients-with-chronic-prostatitis-chronic-pelvic-pain-syndrome
#1
Yusong Lin, Yan Bai, Peng Liu, Xuejuan Yang, Wei Qin, Jianqin Gu, Degang Ding, Jie Tian, Meiyun Wang
The purpose of this study was to explore the neural mechanism in Chronic prostatitis/Chronic pelvic pain syndrome (CP/CPPS) using resting-state functional magnetic resonance imaging. The functional magnetic resonance imaging was performed on 31 male CP/CPPS-patients and 31 age and education matched male healthy controls on a 3-T magnetic resonance imaging unit. A two-sample t-test was adopted to reveal the regional homogeneity between the patients and healthy controls. The mean regional homogeneity values in the alerted brain regions of patients were correlated with the clinical measurements by using Pearson's correlation analyses...
2017: PloS One
https://www.readbyqxmd.com/read/28917110/prevalence-and-predictors-of-potentially-inappropriate-prescribing-of-central-nervous-system-and-psychotropic-drugs-among-elderly-patients-a-national-population-study-in-korea
#2
Hyeonseok Cho, Junjeong Choi, Young-Sang Kim, Sang Joon Son, Kang Soo Lee, Hee-Jin Hwang, Hye-Young Kang
OBJECTIVES: To investigate the prevalence of potentially inappropriate prescribing (PIP) of central nervous system and psychotropic (CNS-PS) drugs to the Korean elderly population, and to identify PIP-associated factors. METHODS: Ambulatory care visits were identified from the 2013 National Aged Patient Sample (HIRA-APS-2013) data, composed of 20% random samples of all enrollees in the universal health security program aged ≥65 years. The CNS-PS section of Screening Tool of Older Person's potentially inappropriate Prescriptions (STOPP) criteria version 2 was used to identify PIP at these visits...
September 6, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28891846/quality-of-life-in-rectal-cancer-patients-after-chemoradiation-watch-and-wait-policy-versus-standard-resection-a-matched-controlled-study
#3
MULTICENTER STUDY
Britt J P Hupkens, Milou H Martens, Jan H Stoot, Maaike Berbee, Jarno Melenhorst, Regina G Beets-Tan, Geerard L Beets, Stéphanie O Breukink
BACKGROUND: Fifteen to twenty percent of patients with locally advanced rectal cancer have a clinical complete response after chemoradiation therapy. These patients can be offered nonoperative organ-preserving treatment, the so-called watch-and-wait policy. The main goal of this watch-and-wait policy is an anticipated improved quality of life and functional outcome in comparison with a total mesorectal excision, while maintaining a good oncological outcome. OBJECTIVE: The aim of this study was to compare the quality of life of watch-and-wait patients with a matched-controlled group of patients who underwent chemoradiation and surgery (total mesorectal excision group)...
October 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28889841/hwanglyunhaedok-pharmacopuncture-versus-saline-pharmacopuncture-on-chronic-nonbacterial-prostatitis-chronic-pelvic-pain-syndrome
#4
Kee Moon Seong, Geurin Jang, Dong Woong Kim, Sungchul Kim, Bong Keun Song
PURPOSE: Chronic nonbacterial prostatitis (CP)/chronic pelvic pain syndrome (CPPS) is known not to have a successful therapy as yet. More recently, acupuncture, some herbal compounds, and trigger point injection have been reported to be beneficial. Pharmacopuncture is an herbal acupuncture having these benefits. The aim of this study was to compare the effect of HP (Hwanglyunhaedok Pharmacopuncture) versus normal saline injection (Saline Pharmacopuncture, SP) on CP/CPPS. METHODS: A retrospective follow up study of 63 patients who were diagnosed with CP/CPPS was performed...
August 2017: Journal of Acupuncture and Meridian Studies
https://www.readbyqxmd.com/read/28875497/cancer-screening-of-older-adults-in-israel-according-to-life-expectancy-cross-sectional-study
#5
Ronen Bareket, Mara A Schonberg, Doron Comaneshter, Yochai Schonmann, Michal Shani, Arnon Cohen, Shlomo Vinker
OBJECTIVES: To examine over-screening of older Israelis for colon and breast cancer. DESIGN: Cross sectional. SETTING: Clalit Health Services (CHS), Israel's largest health maintenance organization (HMO), provides care for more than half of the country's population and operates a national age-based programs for cancer screening. PARTICIPANTS: All community-dwelling members aged 65 to 79 in 2014 (N = 370,876). MEASUREMENTS: We used CHS data warehouse to evaluate cancer screening during 2014...
September 5, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28874332/the-relationship-between-incontinence-and-erectile-dysfunction-after-robotic-prostatectomy-are-they-mutually-exclusive
#6
Savas T Tsikis, Charles U Nottingham, Sarah F Faris
BACKGROUND: Urinary incontinence (UI) and erectile dysfunction (ED) remain the most common long-term complications of prostatectomy, with a significant impact on sexual health and quality of life. AIMS: To determine the relation between UI and moderate to severe ED and the risk factors for UI in patients undergoing robotic-assisted laparoscopic prostatectomy. METHODS: Patients in our institutional database who underwent robotic-assisted laparoscopic prostatectomy for prostate cancer (2006-2013) and who completed the University of California-Los Angeles Prostate Cancer Index and the Sexual Health Inventory for Men (SHIM) surveys at 12 months after prostatectomy were eligible for inclusion...
September 2, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28869721/the-utility-and-feasibility-of-assessing-sleep-disruption-in-a-men-s-health-clinic-using-a-mobile-health-platform-device-a-pilot-study
#7
Hai H Le, Rachel Marie E Salas, Alyssa Gamaldo, Kevin L Billups, Peter Dziedzic, Seulah Choi, Neftali Bermudez, Roland J Thorpe, Charlene E Gamaldo
INTRODUCTION: Evidence linking sleep disruption and sexual dysfunction in men is mounting; yet the characterisation of sleep patterns and complaints utilising a clinically feasible method within this patient population remain largely under-reported. AIM: A pilot study aiming to demonstrate a clinically feasible method to characterise the sleep patterns and complaints in a representative sample of patients treated in a men's health clinic. METHODS: Male patients (n = 48) completed a battery of validated sleep questionnaires using an mHealth mobile platform, MySleepScript, at the Johns Hopkins Men's Health and Vitality Center...
September 4, 2017: International Journal of Clinical Practice
https://www.readbyqxmd.com/read/28869202/short-and-long-term-functional-outcomes-and-quality-of-life-after-radical-prostatectomy-patient-reported-outcomes-from-a-tertiary-high-volume-center
#8
Raisa S Pompe, Zhe Tian, Felix Preisser, Pierre Tennstedt, Burkhard Beyer, Uwe Michl, Markus Graefen, Hartwig Huland, Pierre I Karakiewicz, Derya Tilki
BACKGROUND: Results from population-based studies and the Prostate Testing for Cancer and Treatment trial reported worse urinary continence (UC) and erectile function (EF) for radical prostatectomy (RP) patients compared with their radiation or active surveillance counterparts. OBJECTIVE: To investigate functional outcomes for patients undergoing RP in a high-volume center. DATA, SETTING, AND PARTICIPANTS: A total of 8573 consecutive RP patients (2008-2012) were analyzed...
August 28, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28868504/patient-reported-quality-of-life-recovery-curves-after-robotic-prostatectomy-are-similar-across-body-mass-index-categories
#9
Tullika Garg, Amanda J Young, Korey A Kost, Alyssa M Park, John F Danella, H Lester Kirchner
PURPOSE: To assess the impact of body mass index (BMI) on postoperative recovery curve of urinary and sexual function after robotic-assisted laparoscopic prostatectomy (RALP). We hypothesized that overweight and obese men have different recovery curves than normal weight men. MATERIALS AND METHODS: We reviewed preoperative and postoperative surveys from 691 men who underwent RALP from 2004-2014 in an integrated healthcare delivery system. Survey instruments included: sexual health inventory for men (SHIM), urinary behavior, leakage, and incontinence impact questionnaire (IIQ)...
September 2017: Investigative and Clinical Urology
https://www.readbyqxmd.com/read/28845402/population-based-prostate-cancer-screening-in-kazakhstan
#10
Yevgeniy Ishkinin, Alma Zhylkaidarova, Nurzhan Nurgaliyev, Elmira Auyezova, Ainash Oshibayeva, Nadezhda Gorbunova
BACKGROUND: Issues of mass screening for prostate cancer rather controversial since 2013 in 11 regions of Kazakhstan introduced a population-based screening for prostate cancer, so we need to evaluate its results. METHODS: In different regions of Kazakhstan during 2013-2015, a total of 321548 prostate-specific antigens (PSA) were determined in men aged 50-66 yr, under the Prostate Health Index (PHI) and transrectal ultrasonography (TRUS) guided prostate biopsy with histological examination...
July 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28844600/prostate-specific-antigen-parameters-and-prostate-health-index-enhance-prostate-cancer-prediction-with-the-in-bore-3-t-mri-guided-transrectal-targeted-prostate-biopsy-after-negative-12-core-biopsy
#11
Alexander Friedl, Kathrin Stangl, Wilhelm Bauer, Danijel Kivaranovic, Jenifer Schneeweiss, Martin Susani, Stephan Hruby, Lukas Lusuardi, Fritz Lomoschitz, Edith Eisenhuber-Stadler, Wolfgang Schima, Clemens Brössner
Objectives To assess prostate cancer (PCa) detection and prediction by combining the in-bore MRI-guided transrectal targeted prostate biopsy (MRGB) with prostate-specific antigen (PSA) parameters and the prostate health index (PHI) in case of negative 12-core standard biopsy (SB). Methods A total of 112 males (2014-2016) underwent 3.0T multi-parametric MRI (mpMRI) and subsequent MRGB of Prostate Imaging Reporting and Data System (PI-RADS) lesions 3-5. Ancillary PSA parameters (PSA ratio [%fPSA], PSA density [PSAD]) and the PHI and PHI density (PHID) were recorded...
August 24, 2017: Urology
https://www.readbyqxmd.com/read/28842210/racial-ethnic-and-socioeconomic-disparities-in-prostate-cancer-survivors-prostate-specific-quality-of-life
#12
Heather Orom, Caitlin Biddle, Willie Underwood, Gregory G Homish, Carl Olsson
OBJECTIVE: To conduct a prospective study to examine whether there are pre-treatment and post-treatment disparities in urinary, sexual, and bowel QOL by race/ethnicity, education, or income in men with clinically localized PCa. METHODS: Participants (N=1508; 81% White; 12% Black; 7% Hispanic; 50% surgery; 27% radiotherapy; 23% active surveillance) completed the Expanded Prostate Cancer Index Composite (EPIC-50) measure of PCa-specific QOL prior to treatment, 6 weeks, 6, 12, 18, and 24 months after treatment...
August 22, 2017: Urology
https://www.readbyqxmd.com/read/28831136/multi-factors-including-inflammatory-immune-hormones-tumor-related-proteins-and-nutrition-associated-with-chronic-prostatitis-nih-iiia-b-and-iv-based-on-famhes-project
#13
Yang Chen, Jie Li, Yanling Hu, Haiying Zhang, Xiaobo Yang, Yonghua Jiang, Ziting Yao, Yinchun Chen, Yong Gao, Aihua Tan, Ming Liao, Zhen Lu, Chunlei Wu, Xiaoyin Xian, Suchun Wei, Zhifu Zhang, Wei Chen, Gong-Hong Wei, Qiuyan Wang, Zengnan Mo
Chronic prostatitis (CP) is a complex disease. Fragmentary evidence suggests that factors such as infection and autoimmunity might be associated with CP. To further elucidate potential risk factors, the current study utilized the Fangchenggang Area Male Health and Examination Survey (FAMHES) project; where 22 inflammatory/immune markers, hormone markers, tumor-related proteins, and nutrition-related variables were investigated. We also performed baseline, regression, discriminant, and receiver operating characteristic (ROC) analyses...
August 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28830281/administration-of-daily-5%C3%A2-mg-tadalafil-improves-endothelial-function-in-patients-with-benign-prostatic-hyperplasia
#14
Toshiyasu Amano, Carolyn Earle, Tetsuya Imao, Yuki Matsumoto, Takahiro Kishikage
INTRODUCTION: Tadalafil is a promising phosphodiesterase (PDE) 5 inhibitor prescribed for erectile dysfunction (ED). Daily low dose (5 mg) of tadalafil has also been used for the treatment of male lower urinary tract symptoms (LUTS) associated with benign prostate hyperplasia (BPH). PDE5 inhibitors induce relaxation of smooth muscle cells in the urethra, prostate, bladder neck, and blood vessels. The aim of this study was to investigate the efficacy of tadalafil on vessels endothelial function, in patients with male LUTS symptoms associated with BPH...
August 22, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28828356/relation-between-histological-prostatitis-and-lower-urinary-tract-symptoms-and-erectile-function
#15
Taiki Mizuno, Ippei Hiramatsu, Yusuke Aoki, Hirofumi Shimoyama, Taiji Nozaki, Masato Shirai, Yan Lu, Shigeo Horie, Akira Tsujimura
BACKGROUND: Chronic prostatitis (CP) significantly worsens a patient's quality of life (QOL), but its etiology is heterogeneous. Although the inflammatory process must be associated with CP symptoms, not all patients with benign prostatic hyperplasia and histological prostatitis complain of CP symptoms. The relation between the severity of histological inflammation and lower urinary tract symptoms (LUTS) and erectile function is not fully understood. METHODS: This study comprised 26 men with suspected prostate cancer but with no malignant lesion by pathological examination of prostate biopsy specimens...
September 2017: Prostate International
https://www.readbyqxmd.com/read/28827045/racial-and-ethnic-variation-in-health-related-quality-of-life-scores-prior-to-prostate-cancer-treatment
#16
Stephanie R Reading, Kimberly R Porter, Jeffrey M Slezak, Teresa N Harrison, Joy S Gelfond, Gary W Chien, Steven J Jacobsen
INTRODUCTION: Many men diagnosed with prostate cancer are concerned with how the disease and its course of treatment could affect their health-related quality of life (HRQOL). To aid in the decision-making process on a course of treatment and to better understand how these treatments can affect HRQOL, knowledge of pretreatment HRQOL is essential. AIMS: To assess the racial and ethnic variations in HRQOL scores in men newly diagnosed with prostate cancer before electing a course of treatment...
August 18, 2017: Sexual Medicine
https://www.readbyqxmd.com/read/28811062/validation-of-the-prostate-health-index-in-a-predictive-model-of-prostate-cancer
#17
A Sanchís-Bonet, M Barrionuevo-González, A M Bajo-Chueca, L Pulido-Fonseca, L E Ortega-Polledo, J C Tamayo-Ruiz, M Sánchez-Chapado
OBJECTIVES: To validate and analyse the clinical usefulness of a predictive model of prostate cancer that incorporates the biomarker «[-2] pro prostate-specific antigen» using the prostate health index (PHI) in decision making for performing prostate biopsies. MATERIAL AND METHODS: We isolated serum from 197 men with an indication for prostate biopsy to determine the total prostate-specific antigen (tPSA), the free PSA fraction (fPSA) and the [-2] proPSA (p2PSA)...
August 12, 2017: Actas Urologicas Españolas
https://www.readbyqxmd.com/read/28806263/18f-dcfbc-prostate-specific-membrane-antigen-targeted-pet-ct-imaging-in-localized-prostate-cancer-correlation-with-multiparametric-mri-and-histopathology
#18
Baris Turkbey, Esther Mena, Liza Lindenberg, Stephen Adler, Sandra Bednarova, Rose Berman, Anita T Ton, Yolanda McKinney, Philip Eclarinal, Craig Hill, George Afari, Sibaprasad Bhattacharyya, Ronnie C Mease, Maria J Merino, Paula M Jacobs, Bradford J Wood, Peter A Pinto, Martin G Pomper, Peter L Choyke
PURPOSE: To assess the ability of (N-[N-[(S)-1,3-dicarboxypropyl]carbamoyl]-4-F-fluorobenzyl-L-cysteine) (F-DCFBC), a prostate-specific membrane antigen-targeted PET agent, to detect localized prostate cancer lesions in correlation with multiparametric MRI (mpMRI) and histopathology. METHODS: This Health Insurance Portability and Accountability Act of 1996-compliant, prospective, institutional review board-approved study included 13 evaluable patients with localized prostate cancer (median age, 62...
October 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28804579/validity-of-prostate-health-index-and-percentage-of-2-pro-prostate-specific-antigen-as-novel-biomarkers-in-the-diagnosis-of-prostate-cancer-omani-tertiary-hospitals-experience
#19
Safana S Al Saidi, Nafila B Al Riyami, Mohammed S Al Marhoon, Mohammed S Al Saraf, Salim S Al Busaidi, Riad Bayoumi, Waad-Allah S Mula-Abed
OBJECTIVES: Prostate cancer is the leading cancer in older men. The Ministry of Health Oman Cancer Incidence Registry 2013 lists cancer of the prostate as the first most common cancer in males. Therefore, early detection is important and prostate-specific antigen (PSA) is widely used as an established laboratory test. However, despite its wide use, its value in screening, particularly in asymptomatic males, is controversial when considering the risks and benefits of early detection. METHODS: This prospective, observational study included 136 males (67...
July 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28800293/rotating-shift-work-associated-with-obesity-in-men-from-northeastern-ontario
#20
Anne Grundy, Michelle Cotterchio, Victoria A Kirsh, Victoria Nadalin, Nancy Lightfoot, Nancy Kreiger
INTRODUCTION: While some studies have suggested associations between shift work and obesity, few have been population-based or considered multiple shift schedules. Since obesity is linked with several chronic health conditions, understanding which types of shift work influence obesity is important and additional work with more detailed exposure assessment of shift work is warranted. METHODS: Using multivariate polytomous logistic regression, we investigated the associations between shift work (evening/night, rotating and other shift schedules) and overweight and obesity as measured by body mass index cross-sectionally among 1561 men...
August 2017: Health Promotion and Chronic Disease Prevention in Canada
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