keyword
MENU ▼
Read by QxMD icon Read
search

bab

keyword
https://www.readbyqxmd.com/read/29909590/do-cta-measurements-of-annular-diameter-perimeter-and-area-result-in-different-tavi-prosthesis-sizes
#1
Barbora Horehledova, Casper Mihl, Babs M F Hendriks, Nienke G Eijsvoogel, Jindrich Vainer, Leo F Veenstra, Joachim E Wildberger, Marco Das
Incorrect prosthesis size has direct impact on patient outcome after transcatheter aortic valve implantation (TAVI) procedure. Currently, annular diameter, area or perimeter may be used for prosthesis size selection. The aim was to evaluate whether the use different annular dimensions would result in the selection of different prosthesis sizes, when assessed in the same TAVI-candidate during the same phase of a cardiac cycle. Fifty consecutive TAVI-candidates underwent retrospectively ECG-gated computed tomography angiography (CTA)...
June 16, 2018: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/29909416/non-invasive-detection-of-anastomotic-leakage-following-esophageal-and-pancreatic-surgery-by-urinary-analysis
#2
Victor D Plat, Nora van Gaal, James A Covington, Matthew Neal, Tim G J de Meij, Donald L van der Peet, Babs Zonderhuis, Geert Kazemier, Nanne K H de Boer, Freek Daams
BACKGROUND: Esophagectomy or pancreaticoduodenectomy is the standard surgical approach for patients with tumors of the esophagus or pancreatic head. Postoperative mortality is strongly correlated with the occurrence of anastomotic leakage (AL). Delay in diagnosis leads to delay in treatment, which ratifies the need for development of novel and accurate non-invasive diagnostic tests for detection of AL. Urinary volatile organic compounds (VOCs) reflect the metabolic status of an individual, which is associated with a systemic immunological response...
June 15, 2018: Digestive Surgery
https://www.readbyqxmd.com/read/29870340/effective-sampling-fast-segmentation-using-robust-geometric-model-fitting
#3
Ruwan Tennakoon, Alireza Sadri, Reza Hoseinnezhad, Alireza Bab-Hadiashar
Identifying the underlying models in a set of data points that is contaminated by noise and outliers leads to a highly complex multi-model fitting problem. This problem can be posed as a clustering problem by the projection of higher-order affinities between data points into a graph, which can be clustered using spectral clustering. Calculating all possible higher-order affinities is computationally expensive. Hence, in most cases, only a subset is used. In this paper, we propose an effective sampling method for obtaining a highly accurate approximation of the full graph, which is required to solve multi-structural model fitting problems in computer vision...
September 2018: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/29865821/the-effective-%C3%AF-parameter-in-polarizable-polymeric-systems-one-loop-perturbation-theory-and-field-theoretic-simulations
#4
Douglas J Grzetic, Kris T Delaney, Glenn H Fredrickson
We derive the effective Flory-Huggins parameter in polarizable polymeric systems, within a recently introduced polarizable field theory framework. The incorporation of bead polarizabilities in the model self-consistently embeds dielectric response, as well as van der Waals interactions. The latter generate a χ parameter (denoted χ̃) between any two species with polarizability contrast. Using one-loop perturbation theory, we compute corrections to the structure factor Sk and the dielectric function ϵ^(k) for a polarizable binary homopolymer blend in the one-phase region of the phase diagram...
May 28, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29789875/ct-angiography-in-the-lower-extremity-peripheral-artery-disease-feasibility-of-an-ultra-low-volume-contrast-media-protocol
#5
Barbora Horehledova, Casper Mihl, Gianluca Milanese, Rutger Brans, Nienke G Eijsvoogel, Babs M F Hendriks, Joachim E Wildberger, Marco Das
PURPOSE: The ALARA principle is not only relevant for effective dose (ED) reduction, but also applicable for contrast media (CM) management. Therefore, the aim was to evaluate the feasibility of an ultra-low CM protocol in the assessment of peripheral artery disease (PAD). MATERIALS AND METHODS: Fifty PAD patients were scanned on third-generation dual-source computed tomography, from diaphragm to the forefoot, as follows: tube voltage: 70 kV, reference effective tube current: 90 mAs, collimation: 192 × 2 × 0...
May 22, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29776909/a-bispecific-antibody-targeting-her2-and-her3-suppresses-tumor-growth
#6
(no author information available yet)
Unbiased phenotypic combinatorial screening uncovers a bispecific antibody (bAb) targeting HER2 and HER3.
May 18, 2018: Cancer Discovery
https://www.readbyqxmd.com/read/29769629/risk-of-multiple-pancreatic-cancers-in-cdkn2a-p16-leiden-mutation-carriers
#7
Isaura Ibrahim, Babs G Sibinga Mulder, Bert Bonsing, Hans Morreau, Arantza Farina Sarasqueta, Akin Inderson, Saskia Luelmo, Shirin Feshtali, Thomas P Potjer, Wouter de Vos Tot Nederveen Cappel, Martin Wasser, Hans F A Vasen
CDKN2A-p16-Leiden mutation carriers have a substantial risk of developing pancreatic ductal adenocarcinoma (PDAC). One of the main clinical features of hereditary cancer is the development of multiple cancers. Since 2000, we have run a surveillance program for CDKN2A-p16-Leiden mutation carriers. The patients are offered a yearly MRI with optionally endoscopic ultrasound. In patients with a confirmed lesion, usually, a partial resection of the pancreas is recommended. A total of 18 PDAC (8.3%) were detected in 218 mutation carriers...
May 16, 2018: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/29766022/influence-of-pre-existing-anti-capsid-neutralizing-and-binding-antibodies-on-aav-vector-transduction
#8
Zachary Fitzpatrick, Christian Leborgne, Elena Barbon, Elisa Masat, Giuseppe Ronzitti, Laetitia van Wittenberghe, Alban Vignaud, Fanny Collaud, Séverine Charles, Marcelo Simon Sola, Fabienne Jouen, Olivier Boyer, Federico Mingozzi
Pre-existing immunity to adeno-associated virus (AAV) is highly prevalent in humans and can profoundly impact transduction efficiency. Despite the relevance to AAV-mediated gene transfer, relatively little is known about the fate of AAV vectors in the presence of neutralizing antibodies (NAbs). Similarly, the effect of binding antibodies (BAbs), with no detectable neutralizing activity, on AAV transduction is ill defined. Here, we delivered AAV8 vectors to mice carrying NAbs and demonstrated that AAV particles are taken up by both liver parenchymal and non-parenchymal cells; viral particles are then rapidly cleared, without resulting in transgene expression...
June 15, 2018: Molecular Therapy. Methods & Clinical Development
https://www.readbyqxmd.com/read/29726546/the-role-of-standard-non-ecg-gated-chest-ct-in-cardiac-assessment-design-and-rationale-of-the-cardiac-pathologies-in-standard-chest-ct-capact-study
#9
Nienke G Eijsvoogel, Babs M F Hendriks, Hugo B Park, Sibel Altintas, Casper Mihl, Barbora Horehledova, Bastiaan L J H Kietselaer, Harry J G M Crijns, Joachim E Wildberger, Marco Das
Modern high-performance computed tomography (CT) scanners with improved scan acquisition times now allow for routine assessment of cardiac pathologies on chest CTs, which can result in numerous incidental cardiac findings. The CaPaCT study, an observer blinded, single-centre study, aims to assess the visibility, management and possible clinical impact of incidental cardiac pathologies that are now becoming visible on standard chest CTs. A total of 217 consecutive patients referred for a chest CT on a high-performance third-generation dual-source CT scanner will be included...
2018: European radiology experimental
https://www.readbyqxmd.com/read/29714269/measuring-photoelastic-coefficients-with-schaefer-bergmann-diffraction
#10
Jonathan B Pfeiffer, Kelvin H Wagner
A novel technique for measuring the relative photoelastic coefficients using Schaefer-Bergmann diffraction is introduced and applied to fused silica and α - BaB 2 O 4 . The measurements of fused silica agree with the accepted values to within 0.4%, and the α - BaB 2 O 4 measurements are verified with results presented in this paper from the established Dixon method.
April 1, 2018: Applied Optics
https://www.readbyqxmd.com/read/29693647/anti-interferon-alpha-antibodies-in-patients-with-high-risk-bcr-abl-negative-myeloproliferative-neoplasms-treated-with-recombinant-human-interferon-%C3%AE
#11
Aruna, Limei Li
BACKGROUND The objective of this study was to characterize the incidence and impact of immunogenicity to interferon-a (IFN-α-2a, IFN-α-2b, and Peg-IFN-α-2a) over a period of 12 months in patients with BCR/ABL-negative myeloproliferative neoplasms (MPNs). MATERIAL AND METHODS A total of 131 patients from an observational prospective cohort were selected. Antidrug antibodies, in serial serum samples obtained monthly after initiation of therapy, were measured by ELISA and WISH/VSV CPE assays. The association between antidrug antibodies and treatment response and adverse effects was evaluated...
April 17, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29648477/acute-intensive-care-unit-management-of-mustard-gas-victims-the-turkish-experience
#12
Ertugrul Kilic, Mesut Ortatatli, Sermet Sezigen, Rusen Koray Eyison, Levent Kenar
PURPOSE: Sulphur mustard (SM) is an highly toxic and vesicant chemical weapon that was used in various military conflicts several times in the history. The severity of ocular, dermal, and pulmonary symptoms that may appear following a characteristic asymptomatic period are depending on the SM concentration and exposure duration. The aim of this study is to present the clinical features and share the intensive care unit (ICU) experiences for the medical management of mustard gas victims...
May 7, 2018: Cutaneous and Ocular Toxicology
https://www.readbyqxmd.com/read/29598830/the-putative-amino-acid-abc-transporter-substrate-binding-protein-aapj2-is-necessary-for-brucella-virulence-at-the-early-stage-of-infection-in-a-mouse-model
#13
Mingxing Tian, Yanqing Bao, Peng Li, Hai Hu, Chan Ding, Shaohui Wang, Tao Li, Jingjing Qi, Xiaolan Wang, Shengqing Yu
Brucellosis is a zoonotic bacterial disease caused by Brucella spp. The virulence of these bacteria is dependent on their ability to invade and replicate within host cells. In a previous study, a putative gene bab_RS27735 encoding an amino acid ABC transporter substrate-binding protein homologous to AapJ protein was found to be involved in Brucella abortus virulence. In this study, we successfully constructed a bab_RS27735 deletion mutant, Δ27735. Compared with the wild-type strain, the lipopolysaccharide pattern of the mutant was not changed, but the growth ability was slightly defected in the exponential phase...
March 29, 2018: Veterinary Research
https://www.readbyqxmd.com/read/29583043/effect-of-oral-administration-of-robenacoxib-on-inhibition-of-paracentesis-induced-blood-aqueous-barrier-breakdown-in-healthy-cats
#14
Emily K Sharpe, Jessica M Meekins, James K Roush, Amy J Rankin, Butch KuKanich
OBJECTIVE To determine the effect of oral administration of robenacoxib on inhibition of anterior chamber paracentesis (ACP)-induced breakdown of the blood-aqueous barrier (BAB) and assess whether robenacoxib can cross an intact BAB in healthy cats. ANIMALS 12 healthy adult domestic shorthair cats. PROCEDURES Cats received robenacoxib (6-mg tablet in a treat, PO; n = 6) or a control treatment (treat without any drug, PO; 6) once daily for 3 days, beginning 1 day before ACP. One eye of each cat served as an untreated control, whereas the other underwent ACP, during which a 30-gauge needle was used to aspirate 100 μL of aqueous humor for determination of robenacoxib concentration...
April 2018: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/29488103/multi-centre-phase-iv-trial-to-investigate-the-immunogenicity-of-a-new-liquid-formulation-of-recombinant-human-growth-hormone-in-adults-with-growth-hormone-deficiency
#15
G Johannsson, K Nespithal, U Plöckinger, V Alam, M McLean
PURPOSE: To investigate whether a new liquid formulation of recombinant human growth hormone (r-hGH) induces the production of binding antibodies (BAbs) in adults with congenital or adult-onset growth hormone deficiency (GHD). METHODS: Men or women aged 19-65 years with adult growth hormone deficiency who were r-hGH-naïve or had stopped treatment ≥ 1 month before screening were treated with between 0.15 and 0.30 mg/day r-hGH liquid formulation for 39 weeks...
February 27, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29438139/optimizing-pulmonary-embolism-computed-tomography-in-the-age-of-individualized-medicine-a-prospective-clinical-study
#16
Babs M F Hendriks, Nienke G Eijsvoogel, Madeleine Kok, Bibi Martens, Joachim E Wildberger, Marco Das
PURPOSE: The aim of the study was to simultaneously optimize contrast media (CM) injection and scan parameters for the individual patient during computed tomography pulmonary angiography (CTPA). METHODS: In this study (NCT02611115), 235 consecutive patients suspected of having pulmonary embolism were prospectively enrolled. Automated kV selection software on a third-generation multidetector computed tomography adapted tube voltage to the individual patient, based on scout scans...
May 2018: Investigative Radiology
https://www.readbyqxmd.com/read/29426262/the-relationship-between-theory-of-mind-and-insight-in-obsessive-compulsive-disorder
#17
Rıza Gökçer Tulacı, Eylem Şahin Cankurtaran, Kadir Özdel, Nefise Öztürk, Erkan Kuru, İlker Özdemir
BACKGROUND: It is known that obsessive-compulsive disorder (OCD) patients with poor insight display more severe neuropsychological impairments than other patients with OCD. There are limited studies of OCD and theory of mind (ToM). AIM: To investigate ToM skills in patients with OCD and the relationship between insight and ToM skills by comparing OCD patients with good and poor insight. METHODS: Eighty patients with OCD and 80 healthy controls completed the structured clinical interview for DSM-IV axis I disorders, the Yale Brown Obsessive-Compulsive Scale, the Beck Anxiety and Beck Depression Inventories, and the Brown Assessment of Beliefs Scale...
February 9, 2018: Nordic Journal of Psychiatry
https://www.readbyqxmd.com/read/29362947/morphological-characterization-of-pulmonary-microvascular-disease-in-bronchopulmonary-dysplasia-caused-by-hyperoxia-in-newborn-mice
#18
Hidehiko Nakanishi, Shunichi Morikawa, Shuji Kitahara, Asuka Yoshii, Atsushi Uchiyama, Satoshi Kusuda, Taichi Ezaki
PURPOSE: Pulmonary microvascular injury is associated with the pathogenesis of bronchopulmonary dysplasia (BPD). To characterize the mechanisms of pulmonary vascular disease resulting from BPD, we studied the ultrastructural changes affecting pulmonary microvasculature. METHODS: Newborn ICR mice were exposed to 85% hyperoxia or normoxia for 14 days, and then normal air replacement conditions for the following 7 days. At postnatal day (P)14 and P21, lungs were harvested for ultrastructural examination and assessment of pulmonary hypertension...
January 23, 2018: Medical Molecular Morphology
https://www.readbyqxmd.com/read/29299525/communication-related-affective-behavioral-and-cognitive-reactions-in-speakers-with-spasmodic-dysphonia
#19
Christopher R Watts, Martine Vanryckeghem
Objectives: To investigate the self-perceived affective, behavioral, and cognitive reactions associated with communication of speakers with spasmodic dysphonia as a function of employment status. Study Design: Prospective cross-sectional investigation. Methods: 148 Participants with spasmodic dysphonia (SD) completed an adapted version of the Behavior Assessment Battery (BAB-Voice), a multidimensional assessment of self-perceived reactions to communication...
December 2017: Laryngoscope Investigative Otolaryngology
https://www.readbyqxmd.com/read/29297463/cis-regulatory-evolution-integrated-the-bric-%C3%A3-brac-transcription-factors-into-a-novel-fruit-fly-gene-regulatory-network
#20
Maxwell J Roeske, Eric M Camino, Sumant Grover, Mark Rebeiz, Thomas Michael Williams
Gene expression evolution through gene regulatory network (GRN) changes has gained appreciation as a driver of morphological evolution. However, understanding how GRNs evolve is hampered by finding relevant cis -regulatory element (CRE) mutations, and interpreting the protein-DNA interactions they alter. We investigated evolutionary changes in the duplicated Bric-à-brac (Bab) transcription factors and a key Bab target gene in a GRN underlying the novel dimorphic pigmentation of D. melanogaster and its relatives...
January 3, 2018: ELife
keyword
keyword
27513
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"