keyword
https://read.qxmd.com/read/38537126/developing-accessible-speech-technology-with-users-with-dysarthric-speech
#1
JOURNAL ARTICLE
Elizabeth Howarth, Geena Vabulas, Sean Connolly, Dawn Green, Sara Smolley
The Voiceitt app is designed for people with dysarthric speech, to support vocal communication and access to voice-driven technologies. Sixty-six participants were recruited to test the Voiceitt app and share feedback with developers. Most had physical, sensory, or cognitive impairments in addition to atypical speech. The project team liaised with individuals, their families and local support teams to provide access to the app and associated equipment. Testing was user-led, with participants asked to identify and test use cases most relevant to their daily lives over three months or more...
March 27, 2024: Assistive Technology: the Official Journal of RESNA
https://read.qxmd.com/read/38536131/brain-abscess-secondary-to-streptococcus-intermedius-following-an-egd-with-biopsy-in-a-patient-with-eosinophilic-esophagitis
#2
JOURNAL ARTICLE
N Begum Ozturk, Tatjana Blazin, Aparna Hariharan, Naveen Reddy
Brain abscess is a rare complication of esophagogastro- duodenoscopy (EGD) with few reported cases in the literature. In this report, we discuss a patient presenting with altered mental status, headache, and dysarthria due to brain abscess caused by S. intermedius shortly after an EGD with an esophageal biopsy showing a new diagnosis of eosinophilic esophagitis. We highlight the rare association of EGD and brain abscess, and discuss the importance of prompt diagnosis and treatment.
April 1, 2024: Rhode Island Medical Journal
https://read.qxmd.com/read/38533411/bickerstaff-encephalitis-in-childhood-a-review-of-74-cases-in-the-literature-from-1951-to-today
#3
REVIEW
Luca Gregorio Giaccari, Donatella Mastria, Rosella Barbieri, Rossella De Maglio, Francesca Madaro, Gianfranco Paiano, Maria Caterina Pace, Pasquale Sansone, Giuseppe Pulito, Luciana Mascia
Bickerstaff brainstem encephalitis (BBE) is a rare autoimmune disease characterized by the subacute onset of bilateral external ophthalmoplegia, ataxia, and decreased level of consciousness. BBE is part of a group of rare autoimmune diseases in children that can affect the nervous system at any level. The onset of neurological deficits is often sudden and nonspecific. The diagnosis is based on clinical findings and abnormal findings on cerebrospinal fluid (CSF), electroencephalography (EEG), electromyography (EMG), and magnetic resonance imaging (MRI)...
2024: Frontiers in Neurology
https://read.qxmd.com/read/38532534/unilateral-magnetic-resonance-imaging-guided-laser-interstitial-thermal-therapy-thalamotomy-for-essential-tremor
#4
JOURNAL ARTICLE
Mickael Aubignat, Mélissa Tir, Martial Ouendo, Salem Boussida, Jean-Marc Constans, Michel Lefranc
BACKGROUND: Essential tremor (ET) affects numerous adults, impacting quality of life (QOL) and often defying pharmacological treatment. Surgical interventions like deep brain stimulation (DBS) and lesional approaches, including radiofrequency, gamma-knife radiosurgery, and magnetic resonance imaging (MRI)-guided focused ultrasound, offer solutions but are not devoid of limitations. OBJECTIVES: This retrospective, single-center, single-blinded pilot study aimed to assess the safety and efficacy of unilateral MRI-guided laser interstitial thermal therapy (MRIg-LITT) thalamotomy for medically intractable ET...
March 26, 2024: Movement Disorders: Official Journal of the Movement Disorder Society
https://read.qxmd.com/read/38530396/language-independent-acoustic-biomarkers-for-quantifying-speech-impairment-in-huntington-s-disease
#5
JOURNAL ARTICLE
Vitória S Fahed, Emer P Doheny, Carla Collazo, Joanna Krzysztofik, Elliot Mann, Philippa Morgan-Jones, Laura Mills, Cheney Drew, Anne E Rosser, Rebecca Cousins, Grzegorz Witkowski, Esther Cubo, Monica Busse, Madeleine M Lowery
PURPOSE: Changes in voice and speech are characteristic symptoms of Huntington's disease (HD). Objective methods for quantifying speech impairment that can be used across languages could facilitate assessment of disease progression and intervention strategies. The aim of this study was to analyze acoustic features to identify language-independent features that could be used to quantify speech dysfunction in English-, Spanish-, and Polish-speaking participants with HD. METHOD: Ninety participants with HD and 83 control participants performed sustained vowel, syllable repetition, and reading passage tasks recorded with previously validated methods using mobile devices...
March 26, 2024: American Journal of Speech-language Pathology
https://read.qxmd.com/read/38530100/speech-intelligibility-in-patients-with-facial-paralysis
#6
JOURNAL ARTICLE
Corin M Kinkhabwala, Ryan Puccia, Melissa Montiel, Emily Duckworth, Charles Henry, Judith M Skoner, Laura Hetzler, Samuel Oyer, Krishna G Patel
Background: Patients with facial paralysis often report frustration with communication; however, there are limited data regarding intelligibility deficiencies. Objective: To compare speech intelligibility in patients with severe and non-severe facial paralysis, and in patients with or without synkinesis. Methods: Video and audio data were reviewed retrospectively. Groups were stratified as follows: Group A - severe paralysis (Sunnybrook 0-20) without synkinesis; Group B - non-severe (Sunnybrook >20) paralysis without synkinesis; and Group C - non-severe paralysis with synkinesis...
March 26, 2024: Facial plastic surgery & aesthetic medicine
https://read.qxmd.com/read/38525700/acute-anterior-choroidal-artery-territory-infarction-a-case-series-report
#7
Antonia Tsika, Polyxeni Stamati, Zisis Tsouris, Antonios Provatas, Alexandra Papa, Dimitrios Tsimoulis, Stylliani Ralli, Vasileios Siokas, Efthimios Dardiotis
Due to the occlusion of the anterior choroidal artery (AChA), ischemic strokes are described with the classic clinical triad, namely hemiplegia, hemianesthesia, and homonymous hemianopsia. The aim of this study is to document the characteristic clinical presentation and course of AChA infract cases. We describe five cases with acute infarction in the distribution of the AChA, admitted to the Neurological Department of the University General Hospital of Larissa. Results: All cases presented with hemiparesis and lower facial nerve palsy, while four of them had dysarthria, and two patients exhibited ataxia...
February 29, 2024: Neurology International
https://read.qxmd.com/read/38524138/autoimmune-nodopathy-with-anti-contactin-1-antibody-characterized-by-cerebellar-dysarthria-a-case-report-and-literature-review
#8
REVIEW
Jiajie Chen, Lingchun Liu, Hongyan Zhu, Jinming Han, Rong Li, Xiarong Gong, Hao Fu, Jingjing Long, Haixia Li, Qiang Meng
BACKGROUND: Autoimmune nodopathy (AN) has emerged as a novel diagnostic category that is pathologically different from classic chronic inflammatory demyelinating polyneuropathy. Clinical manifestations of AN include sensory or motor neuropathies, sensory ataxia, tremor, and cranial nerve involvement. AN with a serum-positive contactin-1 (CNTN1) antibody usually results in peripheral nerve demyelination. In this study, we reported a rare case of AN with CNTN1 antibodies characterized by the presence of CNTN1 antibodies in both serum and cerebrospinal fluid, which is associated with cerebellar dysarthria...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38517059/gamma-delta-t-cell-lymphoma-of-the-central-nervous-system-a-case-report-and-review-of-the-literature
#9
JOURNAL ARTICLE
Alexa T Andre, Meagan Chambers, Daniel E Sabath
Primary T-cell lymphoma (TCL) of the central nervous system (CNS) is a rare and potentially aggressive entity. We describe a case of TCL presenting in the basal ganglia with γδ receptor expression and a remarkably aggressive clinical course. To the best of our knowledge, this is the fifth reported case of γδ TCL presenting in the CNS. We review existing literature, including the previously reported cases of γδ TCL of the CNS. In our case, a 69-year-old male presented with acute onset dysarthria and right-sided weakness, with initial imaging concerning for stroke...
March 22, 2024: Clinical Neuropathology
https://read.qxmd.com/read/38516483/lateral-medullary-infarction-with-atonic-bladder-and-lateropulsion
#10
Koji Hayashi, Midori Ueda, Asuka Suzuki, Yuka Nakaya, Hina Hamada, Mamiko Sato, Kouji Hayashi, Yasutaka Kobayashi
Lateral medullary infarction (LMI), or Wallenberg syndrome, can develop various symptoms, but it is rare that ipsilateral axial lateropulsion (or body lateropulsion, BL) or atonic bladder (AB) are caused by LMI. This report describes a case of LMI with both BL and AB. A 77-year-old man, with a history of hypertension and diabetes, developed acute left BL and anuresis. A neurological exam showed right gaze nystagmus, slight dysarthria and dysphagia, right dysesthesia in the trunk, and ataxia in the left limbs and trunk...
February 2024: Curēus
https://read.qxmd.com/read/38513128/%C3%A2-notas-la-diferencia-do-you-hear-the-difference-perceptual-consequences-of-intensive-voice-treatment-in-spanish-speakers-with-parkinson-s-disease
#11
JOURNAL ARTICLE
Gemma Moya-Galé, Jonathan Delgado Hernández, Alireza Goudarzi, Stephen J Walsh
PURPOSE: The primary objective of this study was to explore the effects of intensive voice-focused treatment on speech parameters in Spanish speakers with dysarthria associated with Parkinson's disease (PD) as perceived by naïve listeners. METHOD: Fifteen Spanish speakers with dysarthria associated with PD received the Lee Silverman Voice Treatment (LSVT LOUD) for a month. Voice and speech recordings were conducted pretreatment, posttreatment, and at a 1-month follow-up...
March 21, 2024: Journal of Speech, Language, and Hearing Research: JSLHR
https://read.qxmd.com/read/38512040/exploring-motor-speech-disorders-in-low-and-minimally-verbal-autistic-individuals-an-auditory-perceptual-analysis
#12
JOURNAL ARTICLE
Marc F Maffei, Karen V Chenausky, Abigail Haenssler, Claudia Abbiati, Helen Tager-Flusberg, Jordan R Green
PURPOSE: Motor deficits are widely documented among autistic individuals, and speech characteristics consistent with a motor speech disorder have been reported in prior literature. We conducted an auditory-perceptual analysis of speech production skills in low and minimally verbal autistic individuals as a step toward clarifying the nature of speech production impairments in this population and the potential link between oromotor functioning and language development. METHOD: Fifty-four low or minimally verbal autistic individuals aged 4-18 years were video-recorded performing nonspeech oromotor tasks and producing phonemes, syllables, and words in imitation...
March 21, 2024: American Journal of Speech-language Pathology
https://read.qxmd.com/read/38512013/clinical-insights-into-the-use-of-speech-amplification-devices-for-managing-hypophonia-interviews-with-speech-language-pathologists
#13
JOURNAL ARTICLE
Kelly Gates, Thea Knowles, Helen Mach, Jeff Higginbotham
PURPOSE: The purpose of this qualitative interview study was to identify themes regarding considerations in the usage of speech amplification device usage for people with Parkinson's disease (PD) and hypophonia from the perspective of speech-language pathologists (SLPs). METHOD: Eligible participants included SLPs currently practicing in the United States or Canada with experience working with clients with PD for at least 2 years. Ten SLPs participated in 60-min interviews conducted via Zoom...
March 21, 2024: American Journal of Speech-language Pathology
https://read.qxmd.com/read/38510908/moyamoya-disease-in-a-child-with-fanconi-anemia-an-anomaly-or-a-complication
#14
Samin Alavi, Mitra Khalili, Zahra Khaffafpour, Negar Shams
Fanconi anemia (FA) is an inherited bone marrow failure syndrome associated with congenital anomalies and a predisposition to cancer. We report the case of a 9-year-old boy with FA who developed an abrupt onset of hemiplegia and dysarthria. The diagnosis of moyamoya disease (MMD) was suggested by magnetic resonance angiography (MRA) which demonstrated severe stenosis in the right internal carotid artery along with collateral vessel formation in the right basal ganglia. It is questioned whether the moyamoya pattern in this case is part of congenital malformations associated with FA or is the result of recurrent bleedings around the carotid siphon...
February 2024: Curēus
https://read.qxmd.com/read/38510900/irinotecan-induced-transient-dysarthria-in-a-patient-with-metastatic-colorectal-cancer-a-case-report
#15
Kim Alfred E Inting, Anthony N Piano
We present a rare case of irinotecan-induced transient dysarthria in a 60-year-old female undergoing FOLFIRI (folinic acid (leucovorin), fluorouracil (5-FU), and irinotecan) chemotherapy for metastatic colorectal cancer. In eight out of the 12 cycles, an isolated, self-limiting "lingual dysarthria" with tongue stiffness consistently occurred during infusion and resolved promptly upon completion. Cranial imaging done during the initial episode and after the completion of the chemotherapy regimen were unremarkable...
February 2024: Curēus
https://read.qxmd.com/read/38509662/smartphone-based-speech-therapy-for-post-stroke-dysarthria-a-pilot-randomized-controlled-trial-evaluating-efficacy-and-feasibility
#16
JOURNAL ARTICLE
Yuyoung Kim, Minjung Kim, Jinwoo Kim, Tae-Jin Song
BACKGROUND: Dysarthria is a common post-stroke speech disorder affecting communication and psychological well-being. Traditional speech therapy is effective but often poses challenges in terms of accessibility and patient adherence. Emerging smartphone-based therapies may offer promising alternatives for the treatment of post-stroke dysarthria. OBJECTIVE: This study aimed to assess the efficacy and feasibility of smartphone-based speech therapy for improving speech intelligibility in patients with acute and early subacute post-stroke dysarthria...
March 20, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38508732/-hereditary-sensory-and-autonomic-neuropathy-1e-showing-hyperreflexia-a-case-report
#17
JOURNAL ARTICLE
Hitoshi Hayashida, Yukimasa Arita, Kishin Koh, Yoshihisa Takiyama, Koji Ikezoe
A 52-year-old man had developed hearing loss since childhood, as well as recurrent foot ulcers and osteomyelitis since his forties. He presented with gait disturbance and dysarthria that had worsened over four years and a month, respectively. Neurological exams revealed cognitive impairment, proximal weakness of the lower extremities, generalized hyperrflexia, ataxia, sensory disturbances predominant in deep sensation, urinary retention, and gait instability. On nerve conduction study, no sensory nerve action potentials were evoked in the upper and lower limbs...
March 20, 2024: Rinshō Shinkeigaku, Clinical Neurology
https://read.qxmd.com/read/38476584/clinical-and-imaging-profile-of-patients-with-cerebrotendinous-xanthomatosis-a-video-case-series-from-india
#18
JOURNAL ARTICLE
Pavankumar Katragadda, Vikram V Holla, Nitish Kamble, Jitender Saini, Ravi Yadav, Pramod Kumar Pal
BACKGROUND: Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive disorder caused by bi-allelic pathogenic variants in CYP27A1 gene that results in the deposition of cholestanol in the eyes, tendons, soft tissues and nervous system leading to cataracts, xanthomas, and various neuropsychiatric manifestations. The aim of our study is to describe the clinical, radiological and genetic profile of patients with CTX. METHODS: This is a retrospective chart review of patients with CTX diagnosed based on classical clinical and radiological findings...
2024: Tremor and Other Hyperkinetic Movements
https://read.qxmd.com/read/38473862/pluripotent-stem-cells-as-a-preclinical-cellular-model-for-studying-hereditary-spastic-paraplegias
#19
REVIEW
Devid Damiani, Matteo Baggiani, Stefania Della Vecchia, Valentina Naef, Filippo Maria Santorelli
Hereditary spastic paraplegias (HSPs) comprise a family of degenerative diseases mostly hitting descending axons of corticospinal neurons. Depending on the gene and mutation involved, the disease could present as a pure form with limb spasticity, or a complex form associated with cerebellar and/or cortical signs such as ataxia, dysarthria, epilepsy, and intellectual disability. The progressive nature of HSPs invariably leads patients to require walking canes or wheelchairs over time. Despite several attempts to ameliorate the life quality of patients that have been tested, current therapeutical approaches are just symptomatic, as no cure is available...
February 23, 2024: International Journal of Molecular Sciences
https://read.qxmd.com/read/38466117/functional-and-structural-abnormalities-of-the-speech-disorders-a-multimodal-activation-likelihood-estimation-meta-analysis
#20
JOURNAL ARTICLE
Hao Cai, Jie Dong, Leilei Mei, Genyi Feng, Lili Li, Gang Wang, Hao Yan
Speech disorders are associated with different degrees of functional and structural abnormalities. However, the abnormalities associated with specific disorders, and the common abnormalities shown by all disorders, remain unclear. Herein, a meta-analysis was conducted to integrate the results of 70 studies that compared 1843 speech disorder patients (dysarthria, dysphonia, stuttering, and aphasia) to 1950 healthy controls in terms of brain activity, functional connectivity, gray matter, and white matter fractional anisotropy...
March 1, 2024: Cerebral Cortex
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