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lanthanum carbonate

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https://www.readbyqxmd.com/read/28290356/a-case-of-lanthanum-carbonate-ingestion-thought-to-be-phlebosclerotic-colitis-on-ct-imaging-and-abdominal-radiograph
#1
K Harris, S Balcam
A male admitted in the early hours of the morning, complained of a four week, right sided, non-radiating, dull and intermittent abdominal pain. Imaging suggested a diagnosis of phlebosclerotic colitis which was later discounted when the patients' history of lanthanum carbonate ingestion was examined. Phlebosclerotic colitis mostly affects the Asian population, and its cause is still not known, but can be associated with specific radiographic features. Collections of lanthanum may confuse a diagnosis of phlebosclerotic colitis as well as other factors such as voxel errors, photon starvation and movement...
February 2017: Radiography
https://www.readbyqxmd.com/read/28248961/effects-of-different-phosphate-lowering-strategies-in-patients-with-ckd-on-laboratory-outcomes-a-systematic-review-and-nma
#2
Nigar Sekercioglu, Argie Angeliki Veroniki, Lehana Thabane, Jason W Busse, Noori Akhtar-Danesh, Alfonso Iorio, Luciane Cruz Lopes, Gordon H Guyatt
BACKGROUND: Chronic kidney disease-mineral and bone disorder (CKD-MBD), a complication of chronic kidney disease, has been linked to reduced quality and length of life. High serum phosphate levels that result from CKD-MBD require phosphate-lowering agents, also known as phosphate binders. The objective of this systematic review is to compare the effects of available phosphate binders on laboratory outcomes in patients with CKD-MBD. METHODS: Data sources included MEDLINE and EMBASE from January 1996 to April 2016, and the Cochrane Register of Controlled Trials up to April 2016...
2017: PloS One
https://www.readbyqxmd.com/read/28238013/lanthanum-deposition-in-the-stomach-usefulness-of-scanning-electron-microscopy-for-its-detection
#3
Masaya Iwamuro, Haruo Urata, Takehiro Tanaka, Akemi Ando, Takahiro Nada, Kosuke Kimura, Kenji Yamauchi, Chiaki Kusumoto, Fumio Otsuka, Hiroyuki Okada
After having been treated with lanthanum carbonate administration for 4 years for hyperphosphatemia, a 75-year-old Japanese woman undergoing hemodialysis was diagnosed with lanthanum phosphate deposition in the stomach. The deposition, seen as white microgranules, was observed using esophagogastroduodenoscopy with magnifying observation. To the best of our knowledge, these are the minutest endoscopy images of lanthanum phosphate deposition in the gastric mucosa. Scanning electron microscopy (SEM) observation enabled easier identification of the deposited material, which was visible as bright areas...
February 2017: Acta Medica Okayama
https://www.readbyqxmd.com/read/28182142/elemental-calcium-intake-associated-with-calcium-acetate-calcium-carbonate-in-the-treatment-of-hyperphosphatemia
#4
Rosamund J Wilson, J Brian Copley
BACKGROUND: Calcium-based and non-calcium-based phosphate binders have similar efficacy in the treatment of hyperphosphatemia; however, calcium-based binders may be associated with hypercalcemia, vascular calcification, and adynamic bone disease. SCOPE: A post hoc analysis was carried out of data from a 16-week, Phase IV study of patients with end-stage renal disease (ESRD) who switched to lanthanum carbonate monotherapy from baseline calcium acetate/calcium carbonate monotherapy...
2017: Drugs in Context
https://www.readbyqxmd.com/read/28153426/factors-affecting-gastrointestinal-absorption-of-levothyroxine-a-review
#5
REVIEW
Marko Skelin, Tomo Lucijanić, Daniela Amidžić Klarić, Arnes Rešić, Miro Bakula, Ana-Marija Liberati-Čizmek, Hossein Gharib, Dario Rahelić
PURPOSE: Levothyroxine (LT4) is a drug with a narrow therapeutic index, applied in small amounts (micrograms), which makes interactions in the absorption phase clinically significant. The main aim of this article was to review and present the latest information on factors that affect the gastrointestinal absorption of this drug. METHODS: Relevant data were collected by using the MEDLINE, PubMed, EMBASE, Web of Science, Science Direct, and Scopus databases with the key words levothyroxine and absorption...
February 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/28134986/lanthanum-deposition-from-oral-lanthanum-carbonate-in-the-upper-gastrointestinal-tract
#6
Raza S Hoda, Soma Sanyal, Jerrold L Abraham, Jamie M Everett, Gregory L Hundemer, Eric Yee, Gregory Y Lauwers, Nina Tolkoff-Rubin, Joseph Misdraji
AIMS: Lanthanum carbonate is used as an alternative to calcium-based phosphate binders to manage hyperphosphataemia in patients with renal failure. The deposition of lanthanum within gastroduodenal mucosa of patients treated with the medication has been described, but given the relative novelty of this entity, the histiocytic deposits in the gastroduodenal mucosa can be confused with a variety of other processes, including infections and other drug-induced forms of injury. METHODS AND RESULTS: We describe five cases of lanthanum phosphate deposition in upper gastrointestinal (GI) tract biopsies...
January 30, 2017: Histopathology
https://www.readbyqxmd.com/read/28068585/effects-of-phosphate-binders-on-the-gastrointestinal-absorption-of-arsenate-and-of-an-sglt2-inhibitor-drug-on-the-urinary-excretion-of-arsenite-in-mice
#7
Miklós Poór, Balázs Németi, Zoltán Gregus
Arsenate (As(V)) and arsenite (As(III)) are typical sources of acute and chronic arsenic poisoning. Therefore, reducing inner exposure to these arsenicals is a rational objective. Because As(V) mimics phosphate, phosphate binder drugs may decrease the intestinal As(V) absorption. Indeed, lanthanum and aluminium salts and sevelamer removed As(V) from solution in vitro, especially at acidic pH. In mice gavaged with As(V), lanthanum chloride, lanthanum carbonate and aluminium hydroxide given orally also lowered the urinary excretion and tissue levels of As(V) and its metabolites, indicating that they decreased the gastrointestinal As(V) absorption...
January 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28038714/gastric-mucosal-status-susceptible-to-lanthanum-deposition-in-patients-treated-with-dialysis-and-lanthanum-carbonate
#8
Shinichi Ban, Syunji Suzuki, Kenji Kubota, Susumu Ohshima, Hideaki Satoh, Hiroki Imada, Yoshihiko Ueda
Lanthanum carbonate is a popular chemical which is administered for patients with end-stage kidney disease to reduce the absorption of phosphate, and lanthanum deposition in the gastroduodenal mucosa has recently been reported. The aim of this study was to assess whether any histologic changes of the gastric mucosa are related to the deposition of lanthanum. Twenty-four patients who revealed the histology of lanthanum deposition on gastroduodenal biopsy between 2011 and 2014 were included in the study, and their clinical records and gastroduodenal biopsies obtained from 2011 to 2015 were reviewed, adding the review of gastroduodenal biopsies before 2011 if possible...
February 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/28028242/lanthanide-dependent-cross-feeding-of-methane-derived-carbon-is-linked-by-microbial-community-interactions
#9
Sascha M B Krause, Timothy Johnson, Yasodara Samadhi Karunaratne, Yanfen Fu, David A C Beck, Ludmila Chistoserdova, Mary E Lidstrom
The utilization of methane, a potent greenhouse gas, is an important component of local and global carbon cycles that is characterized by tight linkages between methane-utilizing (methanotrophic) and nonmethanotrophic bacteria. It has been suggested that the methanotroph sustains these nonmethanotrophs by cross-feeding, because subsequent products of the methane oxidation pathway, such as methanol, represent alternative carbon sources. We established cocultures in a microcosm model system to determine the mechanism and substrate that underlay the observed cross-feeding in the environment...
January 10, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/27933814/la2o3-promoted-pd-rgo-electro-catalysts-for-formic-acid-oxidation
#10
Hassan Ali, Fehmida K Kanodarwala, Imran Majeed, John Arron Stride, Muhammad Arif Nadeem
High activity, a low rate of CO poisoning, and long-term stability of Pd electro-catalysts are necessary for practical use as an anode material in direct formic acid fuel cells. Achieving a high degree of Pd nanoparticle dispersion on a carbon support, without agglomeration, while maintaining a facile electron transfer through the catalyst surface are two challenging tasks to be overcome in fulfilling this aim. Herein, we report the effect of addition of La/La-oxides on the efficiency of Pd nanoparticles supported on reduced graphene oxide (rGO) for formic acid electro-oxidation reaction...
November 30, 2016: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/27928636/effects-of-lanthanum-carbonate-and-calcium-carbonate-on-fibroblast-growth-factor-23-and-hepcidin-levels-in-chronic-hemodialysis-patients
#11
Yu-Ming Chang, Shih-Ching Tsai, Chih-Chung Shiao, Hung-Hsiang Liou, Chuan-Lan Yang, Nai-Yu Tung, Kua-Sui Hsu, I-Ling Chen, Mei-Chyn Liu, Jsun-Liang Kao, Rong-Na Jhen, Ya-Ting Huang
BACKGROUND: Phosphate binders have an impact on fibroblast growth factor 23 (FGF23); however, the effect of phosphate binders on serum hepcidin has not been explored. We conducted a 24-week multicenter randomized controlled trial to investigate the effects of lanthanum carbonate or calcium carbonate monotherapy on serum phosphate, FGF23, and hepcidin levels in chronic hemodialysis patients. METHODS: Forty-six patients were recruited, and daily dietary phosphorus was controlled between 600-800 mg...
December 7, 2016: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/27905597/mechanism-for-the-enhanced-oxygen-reduction-reaction-of-la0-6sr0-4co0-2fe0-8o3-%C3%AE-by-strontium-carbonate
#12
Mei Li, Zhongti Sun, Wenqiang Yang, Tao Hong, Zhesheng Zhu, Yanxiang Zhang, Xiaojun Wu, Changrong Xia
Strontium doped lanthanum cobalt ferrite (LSCF) is a widely applied electrocatalyst for the oxygen reduction reaction (ORR) in solid-oxide fuel cells (SOFCs) operated at intermediate temperatures. Sr surface segregation in long-term operation has been reported to have contradicting effects that either degrade or improve the reaction. Thus, it is critical to understand the mechanism of surface Sr compounds on ORR kinetics. This work aims to verify the effect and propose the mechanism by decorating SrCO3 nanoparticles using the infiltration method...
December 21, 2016: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/27803726/lanthanum-carbonate-oral-powder-satisfaction-preference-and-adherence-in-french-and-spanish-patients-with-end-stage-renal-disease
#13
Michael Keith, Patricia de Sequera, François Clair, Riccardo Pedersini
BACKGROUND: Phosphate binders, such as lanthanum carbonate, control elevated serum-phosphate levels in patients with end-stage renal disease (ESRD). Lanthanum carbonate is available in oral powder and tablet form. The aim of this survey was to investigate satisfaction with, preference for, and adherence to lanthanum carbonate oral powder in patients with ESRD. SCOPE: Patients from France and Spain who had been taking lanthanum carbonate powder for at least 4 weeks, and who had experience of other phosphate binders of any formulation, were asked to complete an online or telephone survey...
2016: Drugs in Context
https://www.readbyqxmd.com/read/27677993/assessing-anthropogenic-levels-speciation-and-potential-mobility-of-rare-earth-elements-rees-in-ex-tin-mining-area
#14
Aysha Masood Khan, Ismail Yusoff, Nor Kartini Abu Bakar, Ahmad Farid Abu Bakar, Yatimah Alias
A study was carried out to determine the level of rare earth elements (REEs) in water and sediment samples from ex-mining lakes and River in Kinta Valley, Perak, Malaysia. Surface water and sediments from an ex-mining lake and Kinta River water samples were analyzed for REEs by inductively coupled plasma mass spectrometry. The total concentration of REEs in the ex-mining lake water samples and sediments were found to be 3685 mg/l and 14159 mg/kg, respectively, while the total concentration of REEs in Kinta River water sample was found to be 1224 mg/l...
December 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27659126/effect-of-high-protein-meals-during-hemodialysis-combined-with-lanthanum-carbonate-in-hypoalbuminemic-dialysis-patients-findings-from-the-fredi-randomized-controlled-trial
#15
Connie M Rhee, Amy S You, Tara Koontz Parsons, Amanda R Tortorici, Rachelle Bross, David E St-Jules, Jennie Jing, Martin L Lee, Debbie Benner, Csaba P Kovesdy, Rajnish Mehrotra, Joel D Kopple, Kamyar Kalantar-Zadeh
BACKGROUND: Inadequate protein intake and hypoalbuminemia, indicators of protein-energy wasting, are among the strongest mortality predictors in hemodialysis patients. Hemodialysis patients are frequently counseled on dietary phosphorus restriction, which may inadvertently lead to decreased protein intake. We hypothesized that, in hypoalbuminemic hemodialysis patients, provision of high-protein meals during hemodialysis combined with a potent phosphorus binder increases serum albumin without raising phosphorus levels...
September 22, 2016: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27651467/the-efficacy-and-safety-of-sevelamer-and-lanthanum-versus-calcium-containing-and-iron-based-binders-in-treating-hyperphosphatemia-in-patients-with-chronic-kidney-disease-a-systematic-review-and-meta-analysis
#16
Steven Habbous, Sebastian Przech, Rey Acedillo, Sisira Sarma, Amit X Garg, Janet Martin
Background.: It remains unclear which phosphate binders should be preferred for hyperphosphatemia management in chronic kidney disease (CKD). Methods.: We performed a systematic review and meta-analysis of randomized trials comparing sevelamer or lanthanum with other phosphate binders in CKD. Results.: Fifty-one trials (8829 patients) were reviewed. Compared with calcium-based binders, all-cause mortality was nonsignificantly lower with sevelamer {risk ratio [RR] 0...
January 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27573017/pyrroloquinoline-quinone-ethanol-dehydrogenase-in-methylobacterium-extorquens-am1-extends-lanthanide-dependent-metabolism-to-multicarbon-substrates
#17
Nathan M Good, Huong N Vu, Carly J Suriano, Gabriel A Subuyuj, Elizabeth Skovran, N Cecilia Martinez-Gomez
Lanthanides are utilized by microbial methanol dehydrogenases, and it has been proposed that lanthanides may be important for other type I alcohol dehydrogenases. A triple mutant strain (mxaF xoxF1 xoxF2; named MDH-3), deficient in the three known methanol dehydrogenases of the model methylotroph Methylobacterium extorquens AM1, is able to grow poorly with methanol if exogenous lanthanides are added to the growth medium. When the gene encoding a putative quinoprotein ethanol dehydrogenase, exaF, was mutated in the MDH-3 background, the quadruple mutant strain could no longer grow on methanol in minimal medium with added lanthanum (La(3+))...
November 15, 2016: Journal of Bacteriology
https://www.readbyqxmd.com/read/27554285/role-of-vacancies-light-elements-and-rare-earth-metals-doping-in-ceo2
#18
H Shi, T Hussain, R Ahuja, T W Kang, W Luo
The magnetic properties and electronic structures of pure, doped and defective cerium oxide (CeO2) have been studied theoretically by means of ab initio calculations based on the density function theory (DFT) with the hybrid HF/DFT technique named PBE0. Carbon (C), nitrogen (N), phosphorus (P), sulphur (S), lanthanum (La) and praseodymium (Pr) doped in CeO2 and CeO2 containing oxygen vacancies (Ov) were considered. Our spin-polarized calculations show that C, N, Pr dopants and Ov defects magnetize the non-magnetic CeO2 in different degree...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27545638/-iron-based-phosphate-binders-for-esrd-patients
#19
Mario Cozzolino, Michela Mangano, Lorenza Magagnoli, Luca Di Lullo, Andrea Galassi, Diego Brancaccio, Antonio Bellasi
Several factors influence the choice of phosphate binder for patients, including older age, male gender, post-menopause, diabetes, low bone turnover, vascular/valvular calcification and inflammation. Unlike calcium-based phosphate binders, non-calcium-based phosphate binders, such as sevelamer and lanthanum carbonate, have been able to reduce the progression of bone disease to adynamic bone among patients with CKD. New iron-based phosphate binders are now available. With multiple options available for the reduction of phosphate, the focus has been on agents that do not contain calcium...
July 2016: Giornale Italiano di Nefrologia: Organo Ufficiale Della Società Italiana di Nefrologia
https://www.readbyqxmd.com/read/27520390/penicillium-expansum-link-strain-for-a-biometallurgical-method-to-recover-rees-from-weee
#20
Simone Di Piazza, Grazia Cecchi, Anna Maria Cardinale, Cristina Carbone, Mauro Giorgio Mariotti, Marco Giovine, Mirca Zotti
Due to the wide range of applications in high-tech solutions, Rare Earth Elements (REEs) have become object of great interest. In the last years several studies regarding technologies for REE extraction from secondary resources have been carried out. In particular biotechnologies, which use tolerant and accumulator microorganisms to recover and recycle precious metals, are replacing traditional methods. This paper describes an original biometallurgical method to recover REEs from waste electrical and electronic equipment (WEEE) by using a strain of Penicillium expansum Link isolated from an ecotoxic metal contaminated site...
August 9, 2016: Waste Management
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