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Liver anatomy

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https://www.readbyqxmd.com/read/29131270/imaging-assessment-of-portal-venous-system-pictorial-essay-of-normal-anatomy-anatomic-variants-and-congenital-anomalies
#1
A Guerra, A M De Gaetano, A Infante, C Mele, M G Marini, E Rinninella, R Inchingolo, L Bonomo
The purpose of this pictorial essay is to describe anatomic variants and congenital anomalies of portal venous system and related liver parenchymal alterations. The imaging findings of some of these entities have been previously described in other articles, however this work encompasses all congenital anomalies of portal venous system with attention to their features on various imaging modalities; in particular we illustrated with detailed pictures all the main portal vein variants, congenital extra- and intra-hepatic porto-systemic venous shunts and portal vein aneurysm...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29128992/mapping-of-hepatic-vasculature-in-potential-living-liver-donors-comparison-of-gadoxetic-acid-enhanced-mr-imaging-using-caipirinha-technique-with-ct-angiography
#2
Kartik Jhaveri, Lijun Guo, Luís Guimarães, Ravi Menezes, Ian McGilvray, Mark Cattral, David Grant
PURPOSE: To retrospectively evaluate gadoxetic acid-enhanced magnetic resonance angiography (MRA) using controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) technique for mapping hepatic vascular anatomy in potential living liver donors, with CT angiography (CTA) as reference standard. METHODS: 82 potential living liver donors who underwent MRA and CTA were enrolled in this HIPAA-compliant IRB-approved study. MRA and CTA images were evaluated by two reviewers in consensus with respect to (1) image quality scores for depiction of the hepatic vessels and (2) accuracy of MRA for determining the hepatic vascular variants with CTA as reference standard...
November 11, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/29118686/hepatectomy-for-hilar-cholangiocarcinoma-with-right-sided-ligamentum-teres-using-a-hepatectomy-simulation-system
#3
Seikan Hai, Etsuro Hatano, Tadamichi Hirano, Yasukane Asano, Kazuhiro Suzumura, Hideaki Sueoka, Jiro Fujimoto
Right-sided ligamentum teres (RSLT) is a rare congenital anomaly often accompanied by variation of the hepatic vasculature. We herein report a surgical case of a hilar cholangiocarcinoma with RSLT in whom preoperative hepatectomy simulation proved useful for understanding the anatomical structure of the liver. A 78-year-old male with obstructive jaundice was referred to our department for further examination. The patient was suspected of having a hilar cholangiocarcinoma originating from the left hepatic bile duct by contrast-enhanced computed tomography (CT), and CT also showed right umbilical portion (RUP)...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29114928/a-new-substitute-for-formalin-application-to-embalming-cadavers
#4
Yoshinori Haizuka, Miki Nagase, Satoshi Takashino, Yasushi Kobayashi, Yoshihisa Fujikura, George Matsumura
The development of formalin-free fixatives is an urgent issue in gross anatomy because of the health hazard and the tissue-hardening actions of formalin. We recently identified the fixative, antimicrobial, and preservative effects of N-vinyl-2-pyrrolidone (NVP), a precursor of the water-soluble macromolecular polymer polyvinylpyrrolidone, in animal experiments. The aim of the present study is to investigate whether NVP solution can be used as an alternative to formalin in human cadaveric dissection. Twelve donated cadavers were infused with NVP via the femoral and common carotid arteries using a peristaltic pump...
November 7, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/29102666/a-90-day-subchronic-gavage-toxicity-study-in-fischer-344-rats-with-3-methylfuran
#5
S Gill, M Kavanagh, W Cherry, C Bourque, D Caldwell, G Wang, G Bondy
A 90-day gavage study was conducted with 0.0, 0.02, 0.075, 0.25, 1.0 and 4.0 mg/kg bw/day dose groups of 3-methylfuran to identify a no-observed adverse effect level for hepatotoxicity and to characterize non-neoplastic effects including changes in gross anatomy, histopathology, clinical biochemistry and hematology. There were significant changes in the serum clinical biochemistry markers related to liver injury where males were more affected than the females for most parameters analysed. The serum liver injury marker γ-glutamyltransferase, alanine and aspartate aminotransferases were significantly increased in males in the 4...
November 1, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29096348/3d-printing-model-of-the-intrahepatic-vessels-for-navigation-during-anatomical-resection-of-hepatocellular-carcinoma
#6
Shintaro Kuroda, Tsuyoshi Kobayashi, Hideki Ohdan
INTRODUCTION: The 3D printing model of the intrahepatic vessels and regional anatomy are often used for navigation surgery. Here, we report the use of the model for anatomical resection of hepatocellular carcinoma. PRESENTATION OF CASE: Case 1: A tumor, 31mm in diameter, was located in segment 7 of the liver. Using the 3D model, we identified the regional Glissonian pedicle and performed resection of segment 7. Case 2: The tumor was located in segment 4/8 and involved the middle hepatic vein...
October 26, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29082657/segmental-branching-pattern-of-the-left-portal-vein-anatomical-characteristics-and-clinical-implications
#7
Haythem Najah, Houssem Ammar, Rahul Gupt, Moncef Hamdoun, Abdelwaheb Morjane, Mongi Mighri, Sadok Sassi
INTRODUCTION: The existing knowledge on anatomy of segmental branches of left portal vein (LPV) is limited. This study aims to describe the surgical anatomy and variations of LPV and its segmental branching pattern. MATERIALS AND METHODS: Forty fresh cadaveric liver dissections were performed. The dissection of LPV was carried out from its emergence at the level of the portal vein bifurcation to its segmental branches penetrating the left hemiliver. LPV characteristics, the number and situation of its segmental branches were recorded...
October 30, 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/29078890/novel-mouse-models-of-hepatic-artery-infusion
#8
Minhyung Kim, Daniel T Fisher, Colin A Powers, Emmanuel M Gabriel, Alexis M Korman, Sandra Sexton, Andrei V Gudkov, Joseph J Skitzki
BACKGROUND: The liver has unique anatomy in that most blood flow to normal hepatocytes is derived from the portal venous system, whereas liver tumors obtain their nutrient blood supply exclusively from the hepatic artery. The focused arterial delivery of anticancer agents to liver tumors has been performed for decades; however, preclinical models to standardize drug regimens and examine novel agents have been lacking. The purpose of this study was to establish preclinical hepatic artery infusion (HAI) models in a mouse and to evaluate the safety and delivery capability of the models...
November 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/29078606/depicting-surgical-anatomy-of-the-porta-hepatis-in-living-donor-liver-transplantation
#9
Paul Kelly, Albert Fung, Joy Qu, Paul Greig, Gordon Tait, Jodie Jenkinson, Ian McGilvray, Anne Agur
Visualizing the complex anatomy of vascular and biliary structures of the liver on a case-by-case basis has been challenging. A living donor liver transplant (LDLT) right hepatectomy case, with focus on the porta hepatis, was used to demonstrate an innovative method to visualize anatomy with the purpose of refining preoperative planning and teaching of complex surgical procedures. The production of an animation-enhanced video consisted of many stages including the integration of pre-surgical planning; case-specific footage and 3D models of the liver and associated vasculature, reconstructed from contrast-enhanced CTs...
2017: J Vis Surg
https://www.readbyqxmd.com/read/29067207/abdominal-ultrasonography-of-the-healthy-howler-monkey-alouatta-fusca
#10
Raquel Sartor, Thiago R Müller, Maria J Mamprim, Carlos R Teixeira, Livia P de Souza, Ricardo C Lehmkuhl, Marilia G Luciani
Abdominal ultrasonography was performed in six healthy adult brown howler monkeys Alouatta fusca and the normal ultrasonographic anatomy of the liver, gallbladder, stomach and urinary tract described for the first time. Findings were compared with post-mortem studies. The renal cortex was isoechoic to the spleen and isoechoic or hyperechoic to the liver. Kidney length and renal arterial resistive index, systolic and diastolic velocity were calculated. The liver showed a homogeneous hypoechogenic echotexture...
February 2017: Veterinary Medicine and Science
https://www.readbyqxmd.com/read/29056477/biliary-complications-among-live-donors-following-live-donor-liver-transplantation
#11
Johns Shaji Mathew, K Manikandan, K Y Santosh Kumar, S T Binoj, Dinesh Balakrishnan, Unnikrishnan Gopalakrishnan, Ramachandran Narayana Menon, Puneet Dhar, O V Sudheer, S Aneesh, Surendran Sudhindran
INTRODUCTION: In live donor liver transplantation (LDLT), bile duct division is a critical step in donor hepatectomy. Biliary complications hence are a feared sequelae even among donors. Long term data on biliary complications in donors from India are sparse. METHODS: Prospective evaluation of 452 live donors over 10 years was performed to ascertain the incidence & risk factors of clinically significant biliary complications. RESULTS: Of the 452 donor hepatectomies (M: F = 114:338, median age = 38), 66...
October 19, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/29050064/bilateral-anatomic-resection-of-the-ventral-parts-of-the-paramedian-sectors-of-the-liver-with-total-caudate-lobectomy-for-deeply-centrally-located-liver-tumors-a-new-technique-maximizing-both-oncological-and%C3%A2-surgical-safety
#12
Junichi Shindoh, Yujiro Nishioka, Masaji Hashimoto
Systematic resection of the tumor-bearing portal territory is reportedly correlated with an improved survival of patients with liver tumors, especially in hepatocellular carcinoma. Despite advances in surgical management, however, anatomic resection of deeply/centrally located tumors remains a challenging procedure not only with technical difficulty but also because of decreased hepatic functional reserve frequently observed due to underlying liver disease. In this report, we have reported a novel technique that allows a promising approach for deeply/centrally located tumors with maximizing both the surgical and oncological safety...
October 19, 2017: Journal of Hepato-biliary-pancreatic Sciences
https://www.readbyqxmd.com/read/29032378/survey-results-of-the-expert-meeting-on-laparoscopic-living-donor-hepatectomy-and-literature-review
#13
Jai Young Cho, Ho-Seong Han, Hironori Kaneko, Go Wakabayashi, Hideaki Okajima, Shinji Uemoto, Olivier Soubrane, Chee-Chien Yong, Chao-Long Chen, Tan To Cheung, Giulio Belli, Shoji Kubo, Yao-Ming Wu, Kuo-Hsin Chen, Roberto I Troisi, Choon Hyuck David Kwon, Kyung-Suk Suh, Arvinder S Soin, Ki-Hun Kim, Daniel Cherqui
BACKGROUND: Because laparoscopic donor surgery has been successful in pediatric living donor liver transplantation, its application is expanding to right hepatectomy. However, there is no consensus on the indications for laparoscopic donor hepatectomy or on the details of the surgical technique. OBJECTIVE: To evaluate the current status of laparoscopic donor hepatectomy and to summarize the expert opinion on it. METHODS: Before the expert meeting on September 8, 2016, in Seoul, Korea, a survey was undertaken from expert liver surgeons from around the world...
October 14, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/29030698/biliary-atresia-and-liver-transplantation-results-and-thoughts-for-primary-liver-transplantation-in-select-patients
#14
REVIEW
Riccardo Superina
Biliary atresia (BA) is one of the most common indications for liver transplantation in children. Despite advances in biliary atresia surgical techniques, most children will ultimately require liver transplantation. Possible pre-operative predictors of outcome after the Kasai operation are: 1. Age at operation 2. Presence of the biliary atresia splenic malformation syndrome (BASM) 3. Center specific factors 4. Liver histology and 5. Anatomic pattern of bile ducts found at surgery.Age at surgery is considered a strong predictor of success after portoenterostomy...
December 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29026630/sinister-seafood-bacteraemia-secondary-to-non-o1-o139-vibrio-cholerae-infection
#15
Maxime J Billick, Philip W Lam, Isaac I Bogoch
Introduction.Vibrio species are curved, motile Gram-negative bacilli found in estuarine and marine environments, and are known to cause to gastroenteritis, skin and soft tissue infections, and septicaemia. While not responsible for cholera epidemics, non-O1/O139 Vibrio cholerae (NOVC) is increasingly reported as a cause of gastroenteritis. Case presentation. A 66-year-old man presented to an emergency department with a 1 week history of epigastric pain, emesis and fever. Blood cultures drawn on admission initially demonstrated Gram-negative bacilli, and ultimately grew NOVC, which was later confirmed by matrix-assisted laser desorption ionization-time of flight MS...
July 2017: JMM Case Reports
https://www.readbyqxmd.com/read/29024453/the-histopathologic-reliability-of-tissue-taken-from-cadavers-within-the-gross-anatomy-laboratory
#16
Guenevere Rae, William P Newman, Robin McGoey, Supriya Donthamsetty, Aryn C Karpinski, Jeffrey Green
The purpose of this study was to examine the histopathologic reliability of embalmed cadaveric tissue taken from the gross anatomy laboratory. Tissue samples from hearts, livers, lungs, and kidneys were collected after the medical students' dissection course was completed. All of the cadavers were embalmed in a formalin-based fixative solution. The tissue was processed, embedded in paraffin, sectioned at six micrometers, and stained with H&E. The microscope slides were evaluated by a board certified pathologist to determine whether the cellular components of the tissues were preserved at a high enough quality to allow for histopathologic diagnosis...
October 10, 2017: Anatomical Sciences Education
https://www.readbyqxmd.com/read/29024292/hepatic-cystic-echinococcosis-in-australia-an-update-on-diagnosis-and-management
#17
REVIEW
Ben Keong, Bruce Wilkie, Tom Sutherland, Adrian Fox
BACKGROUND: Echinococcosis is an uncommonly encountered zoonotic disease caused by the taeniid Echinococcus. The only endemic species in Australia, Echinococcus granulosus, forms cysts in the liver in 70% of cases. The aim of this study was to review the literature to provide an evidence-based narrative update on the diagnosis and management of hepatic cystic echinococcosis in Australia. METHODS: We reviewed the literature, utilizing multiple research databases and citation tracking...
October 11, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/29019744/pediatric-liver-transplant-techniques-and-complications
#18
Natally Horvat, Antonio Sergio Zafred Marcelino, Joao Vicente Horvat, Tássia Regina Yamanari, Jose de Arimateia Batista Araújo-Filho, Pedro Panizza, Joao Seda-Neto, Eduardo Antunes da Fonseca, Francisco Cesar Carnevale, Luciana Mendes de Oliveira Cerri, Paulo Chapchap, Giovanni Guido Cerri
Liver transplant is considered to be the last-resort treatment approach for pediatric patients with end-stage liver disease. Despite the remarkable advance in survival rates, liver transplant remains an intricate surgery with significant morbidity and mortality. Early diagnosis of complications is crucial for patient survival but is challenging given the lack of specificity in clinical presentation. Knowledge of the liver and vascular anatomy of the donor and the recipient or recipients before surgery is also important to avoid complications...
October 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28994665/combining-deep-learning-with-anatomy-analysis-for-segmentation-of-portal-vein-for-liver-sbrt-planning
#19
Bulat Ibragimov, Diego Toesca, Daniel Chang, Albert Koong, Lei Xing
Automated segmentation of portal vein (PV) for liver radiotherapy planning is a challenging task due to potentially low vasculature contrast, complex PV anatomy and image artifacts originated from fiducial markers and vasculature stents. In this paper, we propose a novel framework for automated PV segmentation from computed tomography (CT) images. We apply convolutional neural networks (CNN) to learn consistent appearance patterns of PV using a training set of CT images with reference annotations and then enhance PV in previously unseen CT images...
October 10, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28981738/factors-influencing-the-operating-time-for-single-port-laparoscopic-radical-nephrectomy-focus-on-the-anatomy-and-distribution-of-the-renal-artery-and-vein
#20
Kazuhiro Matsumoto, Akira Miyajima, Keishiro Fukumoto, Akari Komatsuda, Naoya Niwa, Seiya Hattori, Toshikazu Takeda, Eiji Kikuchi, Hiroshi Asanuma, Mototsugu Oya
Objective: It is considered that laparoscopic single-site surgery should be performed by specially trained surgeons because of the technical difficulty in using special instruments through limited access. We investigated suitable patients for single-port laparoscopic radical nephrectomy, focusing on the anatomy and distribution of the renal artery and vein. Methods: This retrospective study was conducted in 52 consecutive patients who underwent single-port radical nephrectomy by the transperitoneal approach...
October 1, 2017: Japanese Journal of Clinical Oncology
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