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https://www.readbyqxmd.com/read/28430345/healing-response-of-rat-pulp-treated-with-an-injectable-keratin-hydrogel
#1
Lavanya Ajay Sharma, Robert M Love, Mohammad A Ali, Ajay Sharma, Soraia Macari, Avadhoot Avadhani, George J Dias
BACKGROUND: Keratin has shown promising outcomes as a biomaterial due to its inherent bioactivity, biocompatibility and regenerative effects. The effect of keratin on repair and regeneration of dental tissues has never been studied before. Current therapies to treat pulp tissues involve its replacement with inert, synthetic materials that do not have a proper biological function, leading to failure and tooth loss. This study aimed to develop a biocompatible keratin hydrogel (KH) suitable for pulp therapies...
April 20, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28429488/interdisciplinary-periodontics-the-multidisciplinary-approach-to-the-planning-and-treatment-of-complex-cases
#2
REVIEW
Karl M Lyons, Ivan Darby
Periodontics cannot be practiced in isolation as frequently many patients have multiple dental needs or medical health issues requiring management. In addition, pathology may manifest in the periodontal tissues, and the onset and progression of periodontitis can be affected by systemic conditions, such as diabetes, and vice versa. The focus of this volume of Periodontology 2000 is interdisciplinary periodontics, and the articles included discuss the interactions and the interrelationshipbetween periodontal tissues/periodontal diseases and endodontics, fixed prosthodontics, implant dentistry, esthetics, gerodontology, radiology, orthodontics, pediatric dentistry, oral and maxillofacial surgery, oral pathology, special needs dentistry and general medicine...
June 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28429486/chronic-periodontitis-and-implant-dentistry
#3
REVIEW
Michael M Smith, Ellie T Knight, Latfiya Al-Harthi, Jonathan W Leichter
Dental implants are regularly placed in patients with a history of periodontitis, even though peri-implant tissues are susceptible to the same host-modulated plaque-induced factors that initiate and sustain periodontitis. This article endeavors to clarify the evidence regarding the history of periodontitis as a risk factor for implant success and survival, and the role of supportive periodontal therapy in maintaining implants for individuals with a history of periodontitis.
June 2017: Periodontology 2000
https://www.readbyqxmd.com/read/28427837/in-vitro-fatigue-tests-and-in-silico-finite-element-analysis-of-dental-implants-with-different-fixture-abutment-joint-types-using-computer-aided-design-models
#4
Satoshi Yamaguchi, Yasufumi Yamanishi, Lucas S Machado, Shuji Matsumoto, Nick Tovar, Paulo G Coelho, Van P Thompson, Satoshi Imazato
PURPOSE: The aim of this study was to evaluate fatigue resistance of dental fixtures with two different fixture-abutment connections by in vitro fatigue testing and in silico three-dimensional finite element analysis (3D FEA) using original computer-aided design (CAD) models. METHODS: Dental implant fixtures with external connection (EX) or internal connection (IN) abutments were fabricated from original CAD models using grade IV titanium and step-stress accelerated life testing was performed...
April 17, 2017: Journal of Prosthodontic Research
https://www.readbyqxmd.com/read/28425209/identification-of-dynamic-load-for-prosthetic-structures
#5
Dequan Zhang, Xu Han, Zhongpu Zhang, Jie Liu, Chao Jiang, Nobuhiro Yoda, Xianghua Meng, Qing Li
Dynamic load exists in numerous biomechanical systems and its identification signifies a critical issue for characterizing dynamic behaviors and studying biomechanical consequence of the systems. This study aims to identify dynamic load in the dental prosthetic structures, namely three-unit implant-supported fixed partial denture (I-FPD) and teeth-supported fixed partial denture (T-FPD). The three-dimensional (3D) finite element (FE) models were constructed through patient's computerized tomography (CT) images...
April 20, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28422058/melatonin-a-review-of-its-potential-functions-and-effects-on-dental-diseases
#6
REVIEW
Maria Permuy, Mónica López-Peña, Antonio González-Cantalapiedra, Fernando Muñoz
Melatonin is a hormone synthesised and secreted by the pineal gland and other organs. Its secretion, controlled by an endogenous circadian cycle, has been proven to exert immunological, anti-oxidant, and anti-inflammatory effects that can be beneficial in the treatment of certain dental diseases. This article is aimed at carrying out a review of the literature published about the use of melatonin in the dental field and summarising its potential effects. In this review article, an extensive search in different databases of scientific journals was performed with the objective of summarising all of the information published on melatonin use in dental diseases, focussing on periodontal diseases and dental implantology...
April 19, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28421736/enhancing-the-bioactivity-of-yttria-stabilized-tetragonal-zirconia-ceramics-via-grain-boundary-activation
#7
Jinhuan Ke, Jiandong Ye, Fupo He
Yttria-stabilized tetragonal zirconia (Y-TZP) has been proposed as a potential dental implant due to its good biocompatibility, excellent mechanical properties, and distinctive aesthetic effect. However, Y-TZP cannot form chemical bonds with bone tissue because of its biological inertness, which affects the reliability and long-term efficacy of Y-TZP implants. In this study, to improve the bioactivity of Y-TZP ceramics while maintaining their good mechanical performance, Y-TZP was modified by grain boundary activation via the infiltration of a bioactive glass (BG) sol into the surface layer of Y-TZP ceramics under different negative pressures (atmospheric pressure, -0...
April 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28421148/multidisciplinary-approach-in-the-management-of-a-complex-case-implant-prosthetic-rehabilitation-of-a-periodontal-smoking-patient-with-partial-edentulism-malocclusion-and-aesthetic-diseases
#8
Alessandro Lanza, Fabrizio Di Francesco, Gennaro De Marco, Fabio Scognamiglio, Valeria Aruta, Angelo Itro
Complex periprosthetic cases are considered as challenges by clinicians. Clinical and radiographic parameters should be considered separately to make the right choice between an endodontically or periodontally compromised treated tooth and implant. Therefore, in order to decide whether the tooth is safe or not, data that have to be collected are specific parameters of both the patient and the clinician. In addition, the presence of periodontal, prosthetic, and orthodontic diseases requires patients to be set in multidisciplinary approach...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28416317/zinc-oxide-inhibits-dental-discoloration-caused-by-white-mineral-trioxide-aggregate-angelus
#9
Marina Angélica Marciano, Josette Camilleri, Reginaldo Mendonça Costa, Mariza Akemi Matsumoto, Bruno Martini Guimarães, Marco Antonio Hungaro Duarte
INTRODUCTION: The aim of the study was to investigate the addition of variable amounts of zinc oxide to inhibit dental discoloration caused by mineral trioxide aggregate (MTA) Angelus. METHODS: MTA Angelus and MTA with additions of 5%, 15%, and 45% zinc oxide (ZnO) in weight were tested. The set cements were characterized by using a combination of scanning electron microscopy, energy dispersive spectroscopy, and x-ray diffraction. Radiopacity and setting time were analyzed according to American National Standards Institute/American Dental Association (57/2012) and American Society for Testing and Materials (C266-08)...
April 14, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28416308/implantation-of-endothelial-cells-with-mesenchymal-stem-cells-accelerates-dental-pulp-tissue-regeneration-healing-in-pulpotomized-rat-molars
#10
Yukiko Sueyama, Tomoatsu Kaneko, Takafumi Ito, Reika Kaneko, Takashi Okiji
INTRODUCTION: This study aimed to examine whether the implantation of mesenchymal stem cells (MSCs) with endothelial cells (ECs) accelerates pulp tissue regeneration/healing and induces dentin bridge formation in a rat model of molar coronal pulp regeneration. METHODS: The maxillary first molars of Wistar rats were subjected to pulpotomy. Then, pulp chambers were implanted with biodegradable hydrogel-made scaffolds carrying MSCs together or without dermal microvascular ECs, and the cavities were sealed with mineral trioxide aggregate...
April 14, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28415545/engineering-bone-regeneration-with-novel-cell-laden-hydrogel-microfiber-injectable-calcium-phosphate-scaffold
#11
Yang Song, Chi Zhang, Ping Wang, Lin Wang, Chunyun Bao, Michael D Weir, Mark A Reynolds, Ke Ren, Liang Zhao, Hockin H K Xu
Cell-based tissue engineering is promising to create living functional tissues for bone regeneration. The implanted cells should be evenly distributed in the scaffold, be fast-released to the defect and maintain high viability in order to actively participate in the regenerative process. Herein, we report an injectable calcium phosphate cement (CPC) scaffold containing cell-encapsulating hydrogel microfibers with desirable degradability that could deliver cells in a timely manner and maintain cell viability...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28415466/effect-of-lubricant-on-the-reliability-of-dental-implant-abutment-screw-joint-an-in-vitro-laboratory-and-three-dimension-finite-element-analysis
#12
Tingting Wu, Hongyi Fan, Ruiyang Ma, Hongyu Chen, Zhi Li, Haiyang Yu
Biomechanical factors play a key role in the success of dental implants. Fracture and loosening of abutment screws are major issues. This study investigated the effect of lubricants on the stability of dental implant-abutment connection. As lubricants, graphite and vaseline were coated on the abutment screw surface, respectively, and a blank without lubricant served as the control. The total friction coefficient (μtot), clamping force, fatigue behavior and detorque of the joint combined with dynamic cyclic loading were measured under different lubricating conditions...
June 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28414986/modelling-dental-implant-extraction-by-pullout-and-torque-procedures
#13
D Rittel, A Dorogoy, K Shemtov-Yona
Dental implants extraction, achieved either by applying torque or pullout force, is used to estimate the bone-implant interfacial strength. A detailed description of the mechanical and physical aspects of the extraction process in the literature is still missing. This paper presents 3D nonlinear dynamic finite element simulations of a commercial implant extraction process from the mandible bone. Emphasis is put on the typical load-displacement and torque-angle relationships for various types of cortical and trabecular bone strengths...
April 11, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28413151/public-and-patient-knowledge-about-dental-implants
#14
George Deeb, Bryan Wheeler, Margaret Jones, Caroline Carrico, Daniel Laskin, Janina Golob Deeb
PURPOSE: The more informed a patient is about a given procedure, the better the ultimate outcome. This study was designed to compare general public awareness and knowledge regarding oral implant treatment with those of patients presenting for such treatment and to determine the sources from which they may have obtained such information, as well as the accuracy of the information. PATIENTS AND METHODS: In this cross-sectional study, 2 groups of patients were asked to complete a questionnaire containing implant knowledge questions and questions regarding any sources they may have used to obtain information about dental implants...
March 23, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28412266/hyperparathyroidism-diagnosed-due-to-brown-tumors-of-the-jaw-a-case-report-and-literature-review
#15
Philip Brabyn, Ana Capote, Marko Belloti, Ian Zylberberg
This report describes the case of a 42-year-old woman who consulted with a maxillofacial specialist for pain and an exophytic lesion in the maxilla. Biopsy examination disclosed a bone cyst with abundant giant cells, and head and neck computed tomography was performed. A diagnosis of brown tumor in the maxilla and mandible was made, and primary hyperparathyroidism (parathyroid adenoma) was determined as the origin of the bone lesions. The patient underwent a left superior parathyroidectomy, which resolved the hormonal disorder (as determined by normal calcium and parathyroid hormone levels) and the brown tumors, which appeared to have mineralized at 1-year follow-up computed tomography...
March 20, 2017: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28411136/augmentation-of-keratinized-gingiva-around-dental-implants
#16
Kissa Jamila, El Kholti Wafa, Laalou Younes, El Farouki Mohamed
To date, there is no general consensus with respect to the amount of soft-tissue volume needed for esthetic and functional purposes on the buccal aspect of dental implants. Numerous studies have investigated the relationship between the width of keratinized mucosa and the health of peri-implant tissues. Our purpose was to discuss about the necessity of keratinized tissue to maintain the peri-implant health and to report clinical efficacy of different technics used to increase the keratinized tissue around dental implants...
April 11, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28410532/role-of-p16-ink4a-and-bmi-1-in-oxidative-stress-induced-premature-senescence-in-human-dental-pulp-stem-cells
#17
Cristina Mas-Bargues, José Viña-Almunia, Marta Inglés, Jorge Sanz-Ros, Juan Gambini, José Santiago Ibáñez-Cabellos, José Luis García-Giménez, José Viña, Consuelo Borrás
Human dental pulp stem cells (hDPSCs) are a source for cell therapy. Before implantation, an in vitro expansion step is necessary, with the inconvenience that hDPSCs undergo senescence following a certain number of passages, loosing their stemness properties. Long-term in vitro culture of hDPSCs at 21% (ambient oxygen tension) compared with 3-6% oxygen tension (physiological oxygen tension) caused an oxidative stress-related premature senescence, as evidenced by increased β-galactosidase activity and increased lysil oxidase expression, which is mediated by p16(INK4a) pathway...
April 7, 2017: Redox Biology
https://www.readbyqxmd.com/read/28407420/dental-biofilm-infections-an-update
#18
REVIEW
Tove Larsen, Nils-Erik Fiehn
Teeth are colonized by oral bacteria from saliva containing more than 700 different bacterial species. If removed regularly, the dental biofilm mainly comprises oral streptococci and is regarded as resident microflora. But if left undisturbed, a complex biofilm containing up to 100 bacterial species at a site will build up and may eventually cause development of disease. Depending on local ecological factors, the composition of the dental biofilm may vary considerably. With access to excess carbohydrates, the dental biofilm will be dominated by mainly gram-positive carbohydrate-fermenting bacteria causing demineralization of teeth, dental caries, which may further lead to inflammation and necrosis in the pulp and periapical region, i...
April 2017: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
https://www.readbyqxmd.com/read/28406881/early-healing-evaluation-of-commercially-pure-titanium-and-ti-6al-4v-presenting-similar-surface-texture-an-in-vivo-study
#19
Arthur Castellano, Luiz F Gil, Estevam A Bonfante, Nick Tovar, Rodrigo Neiva, Malvin N Janal, Paulo G Coelho
OBJECTIVE: This study evaluated the osseointegration of commercially pure titanium (Ti) grade-2 (G2) and Ti-6Al-4V alloy (G5) implants with the same geometry and surface treatment. MATERIALS AND METHODS: Thirty-six dental implants with a grit-blasted acid-etched surface were used (n = 18, each). Two implants, one per group, were installed in each subject, in the radius diaphysis (n = 18 beagle dogs), with interchanged fixture position (proximal-distal) between animals for a balanced number of devices per group and time in vivo (1, 3, and 6 weeks)...
April 12, 2017: Implant Dentistry
https://www.readbyqxmd.com/read/28406458/behavior-of-human-osteoblast-cells-cultured-on-titanium-discs-in-relation-to-surface-roughness-and-presence-of-melatonin
#20
M Fernanda Sola-Ruiz, Carolina Perez-Martinez, Carlos Labaig-Rueda, Carmen Carda, J Javier Martín De Llano
The aim of this work was to observe the behavior of osteoblast cells cultured in vitro on titanium discs in relation to disc surface roughness and the addition of melatonin to the culture medium. MG63 osteoblast cells were cultivated on 120 Grade 5 Ti divided into three groups: Group E, treated with dual acid etch; Group EP, treated with dual acid etch and calcium phosphate; and Group M, machined. Surface roughness was examined under a laser scanning confocal microscope (CLSM) and scanning electron microscopy (SEM)...
April 13, 2017: International Journal of Molecular Sciences
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