Zhennan Liao, Dandan Li, Shengyou Liao, Zhipeng Zeng, Jiayi Liu, Ting Xie, Bo Hu, Wei Wang, Xiaoping Hong, Dongzhou Liu, Lianghong Yin, Donge Tang, Yong Dai
Primary Sjogren's Syndrome (pSS) is a chronic autoimmune disease, with unclear pathogenies. Lysine-malonylation (Kmal) as a novel post-translational modification (PTMs) was found associated with metabolic, immune, and inflammatory processes. For purpose of investigating the proteomic profile and functions of kmal in pSS, liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based analysis and bioinformatics analysis are performed based on twenty-eight pSS patients versus twenty-seven healthy controls (HCs)...
July 21, 2023: Journal of Proteomics