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body plethysmography

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https://www.readbyqxmd.com/read/29767787/sleep-disordered-breathing-in-c57bl-6j-mice-with-diet-induced-obesity
#1
Thomaz Fleury Curado, Huy Pho, Slava Berger, Candela Caballero-Eraso, Mi-Kyung Shin, Luiz Ubirajara Sennes, Luu Pham, Alan R Schwartz, Vsevolod Y Polotsky
Obesity leads to sleep disordered breathing (SDB), as manifested by recurrent upper airway obstructions during sleep termed obstructive sleep apnea and carbon dioxide retention due to obesity hypoventilation. The objective of this work was to characterize breathing during sleep in C57BL6/J mice with diet-induced obesity. Arterial blood gas was measured in nine obese and nine lean mice during wakefulness. Nine male mice with diet induced obesity and six lean male C57BL/6J mice were head mounted with EEG and EMG electrodes...
May 15, 2018: Sleep
https://www.readbyqxmd.com/read/29767680/propensity-for-adverse-pregnancy-outcomes-in-african-american-women-may-be-explained-by-low-energy-expenditure-in-early-pregnancy
#2
Jasper Most, L Anne Gilmore, Abby D Altazan, Marshall St Amant, Robbie A Beyl, Eric Ravussin, Leanne M Redman
Background: African-American (AA) women have poorer pregnancy outcomes and studies in nonpregnant women suggest a different etiology of weight gain in AA compared with white women. We hypothesized that physiologic factors such as low energy expenditure and physical activity would be present in AA compared with white women in pregnancy. Objective: We aimed to identify physiologic risk factors for disordered energy balance in AA and white women early in pregnancy...
May 14, 2018: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29758496/cord-blood-concentrations-of-leptin-zinc-%C3%AE-2-glycoprotein-and-adiponectin-and-adiposity-gain-during-the-first-3-mo-of-life
#3
Verônica L V Euclydes, Natalia P Castro, Lourdes R Lima, Cyro Brito, Laisa Ribeiro, Fernanda Agapito Simões, Guaraci Requena, Liania Alves Luzia, Patricia Helen Rondó
OBJECTIVES: Adipose tissue development starts in intrauterine life and cytokines are involved in this process. Therefore, understanding the role of cytokines in the fat mass gain of infants is crucial to prevent obesity later in life. Furthermore, recent evidence indicates a sex-specific link between cytokines and adipose tissue development. The objective of this study was to assess sex-specific relationships of cord blood concentrations of the cytokines leptin, zinc-α2-glycoprotein (ZAG), and adiponectin with infant adiposity during the first 3 mo of life...
March 22, 2018: Nutrition
https://www.readbyqxmd.com/read/29750877/respiratory-induced-hemodynamic-changes-measured-by-whole-body-multichannel-impedance-plethysmography
#4
P Langer, P Jurák, V Vondra, J Halámek, M Mešťaník, I Tonhajzerová, I Viščor, L Soukup, M Matejkova, E Závodná, P Leinveber
The cardiovascular system is described by parameters including blood flow, blood distribution, blood pressure, heart rate and pulse wave velocity. Dynamic changes and mutual interactions of these parameters are important for understanding the physiological mechanisms in the cardiovascular system. The main objective of this study is to introduce a new technique based on parallel continuous bioimpedance measurements on different parts of the body along with continuous blood pressure, ECG and heart sound measurement during deep and spontaneous breathing to describe interactions of cardiovascular parameters...
May 10, 2018: Physiological Research
https://www.readbyqxmd.com/read/29748651/advances-in-assessing-body-composition-during-pregnancy
#5
REVIEW
Jasper Most, Kara Lynn Marlatt, Abby Duhé Altazan, Leanne Maree Redman
The prevalence of excess gestational weight gain is increasing worldwide and is associated with pregnancy complications, including gestational diabetes mellitus, pre-eclampsia, preterm birth, macrosomia, and development of obesity in offspring. Whereas gestational weight gain positively correlates with the gain in fat mass (FM), fat-free mass (FFM) gain is relatively consistent across pregnancies. Commonly used methods to assess body composition include anthropometry, densitometry (air displacement plethysmography, underwater weighing), and hydrometry (isotope dilution, bioimpedance analysis)...
May 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29744248/high-dose-of-pralidoxime-reverses-paraoxon-induced-respiratory-toxicity-in-mice
#6
Pascal Houzé, Thomas Berthin, Jean-Herlé Raphalen, Alice Hutin, J Frédéric Baud
Objective: The efficiency of pralidoxime in the treatment of human organophosphates poisoning is still unclear. In a rat model, we showed that pralidoxime induced a complete but concentration-dependent reversal of paraoxon-induced respiratory toxicity. The aim of this study was to assess the efficiency of pralidoxime in a species other than rats. Methods: A dose of diethylparaoxon corresponding to 50% of the median lethal dose was administered subcutaneously to male F1B6D2 mice...
April 2018: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/29742906/relationship-of-spirometric-body-plethysmographic-and-diffusing-capacity-parameters-to-emphysema-scores-derived-from-ct-scans
#7
Kathrin Kahnert, Bertram Jobst, Frank Biertz, Jürgen Biederer, Henrik Watz, Rudolf M Huber, Jürgen Behr, Philippe A Grenier, Peter Alter, Claus F Vogelmeier, Hans-Ulrich Kauczor, Rudolf A Jörres
Phenotyping of chronic obstructive pulmonary disease (COPD) with computed tomography (CT) is used to distinguish between emphysema- and airway-dominated type. The phenotype is reflected in correlations with lung function measures. Among these, the relative value of body plethysmography has not been quantified. We addressed this question using CT scans retrospectively collected from clinical routine in a large COPD cohort. Three hundred and thirty five patients with baseline data of the German COPD cohort COPD and Systemic Consequences-Comorbidities Network were included...
January 1, 2018: Chronic Respiratory Disease
https://www.readbyqxmd.com/read/29739793/association-between-adiposity-and-lean-mass-with-long-term-cardiovascular-events-in-patients-with-coronary-artery-disease-no-paradox
#8
Jose R Medina-Inojosa, Virend K Somers, Randal J Thomas, Nathalie Jean, Sarah M Jenkins, Miguel Angel Gomez-Ibarra, Marta Supervia, Francisco Lopez-Jimenez
BACKGROUND: Prognosis based on body fat percentage (BF%) in patients with coronary artery disease has not been extensively studied. We tested the hypothesis that patients with coronary artery disease and increased BF% have a higher risk for major adverse cardiovascular events (MACEs) and that fat-free mass is associated with better prognosis. METHODS AND RESULTS: We included 717 patients referred to cardiac rehabilitation after coronary artery disease events or procedures who underwent air displacement plethysmography to assess BF%; 75% were men, with a mean age 61...
May 8, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29739682/multispecies-probiotics-combination-prevents-ovalbumin-induced-airway-hyperreactivity-in-mice
#9
Jui-Cheng Chen, Cheng-Chih Tsai, Chang-Chi Hsieh, Alice Lan, Chun-Chih Huang, Sew-Fen Leu
BACKGROUND: Probiotics could be beneficial to health and some of them have shown to modulate immune responses. AIM: The aim of this study is to investigate if the probiotic strains including Lactobacillus and Pediococcus strains are able to alleviate allergic reactions in an ovalbumin-induced airway allergy model. METHODS: Lactobacillus multi-species preparation (LMP) was gavaged to BALB/c for total six weeks and BALB/c was challenged with ovalbumin in the last two weeks...
May 5, 2018: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/29717270/biological-and-psychological-mediators-of-the-relationships-between-fat-mass-fat-free-mass-and-energy-intake
#10
Mark Hopkins, Graham Finlayson, Cristiana Duarte, Catherine Gibbons, Alexandra M Johnstone, Stephen Whybrow, Graham W Horgan, John E Blundell, R James Stubbs
BACKGROUND: While recent studies in humans indicate that fat-free mass (FFM) is closely associated with energy intake (EI) when in energy balance, associations between fat mass (FM) and EI are inconsistent. OBJECTIVES: The present study used a cross-sectional design to examine the indirect and direct effects of FFM, FM and resting metabolic rate (RMR) on EI in individuals at or close to energy balance. METHODS: Data for 242 individuals (114 males; 128 females; BMI = 25...
March 13, 2018: International Journal of Obesity: Journal of the International Association for the Study of Obesity
https://www.readbyqxmd.com/read/29713160/static-and-dynamic-hyperinflation-during-severe-acute-exacerbations-of-chronic-obstructive-pulmonary-disease
#11
Wouter H van Geffen, Huib Am Kerstjens
Background: Static hyperinflation is known to be increased during moderate acute exacerbations of chronic obstructive pulmonary disease (COPD) (AECOPD), but few data exist in patients with severe exacerbations of COPD. The role of dynamic hyperinflation during exacerbations is unclear. Methods: In a prospective, observational cohort study, we recruited patients admitted to hospital for AECOPD. The following measurements were performed upon admission and again after resolution (stable state) at least 42 days later: inspiratory capacity (IC), body plethysmography, dynamic hyperinflation by metronome-paced IC measurement, health-related quality of life and dyspnea...
2018: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29697839/brain-derived-erythropoietin-protects-from-intermittent-hypoxia-induced-cardiorespiratory-dysfunction-and-oxidative-stress-in-mice
#12
Elizabeth Elliot-Portal, Sofien Laouafa, Christian Arias-Reyes, Tara Adele Janes, Vincent Joseph, Jorge Soliz
Study Objectives: Based on the fact that erythropoietin (Epo) administration in rodents protects against spatial learning and cognitive deficits induced by chronic intermittent hypoxia (CIH)-mediated oxidative damage, here we tested the hypothesis that Epo in the brain protects against cardiorespiratory disorders and oxidative stress induced by CIH in adult mice. Methods: Adult control and transgenic mice overexpressing Epo in the brain only (Tg21) were exposed to CIH (21%-10% O2-10 cycles/hour-8 hours/day-7 days) or room air...
April 25, 2018: Sleep
https://www.readbyqxmd.com/read/29695707/high-orange-juice-consumption-with-or-in-between-three-meals-a-day-differently-affects-energy-balance-in-healthy-subjects
#13
Franziska A Hägele, Franziska Büsing, Alessa Nas, Julian Aschoff, Lena Gnädinger, Ralf Schweiggert, Reinhold Carle, Anja Bosy-Westphal
Sugar-containing beverages like orange juice can be a risk factor for obesity and type 2 diabetes although the underlying mechanisms are less clear. We aimed to investigate if intake of orange juice with or in-between meals differently affects energy balance or metabolic risk. Twenty-six healthy adults (24.7 ± 3.2 y; BMI 23.2 ± 3.2 kg/m2 ) participated in a 4-week cross-over intervention and consumed orange juice (20% of energy requirement) either together with 3 meals/d (WM) or in-between 3 meals/d (BM) at ad libitum energy intake...
April 25, 2018: Nutrition & Diabetes
https://www.readbyqxmd.com/read/29690880/abnormal-pulmonary-function-tests-predict-the-development-of-radiation-induced-pneumonitis-in-advanced-non-small-cell-lung-cancer
#14
L Torre-Bouscoulet, W R Muñoz-Montaño, D Martínez-Briseño, F J Lozano-Ruiz, R Fernández-Plata, J A Beck-Magaña, C García-Sancho, A Guzmán-Barragán, E Vergara, M Blake-Cerda, L Gochicoa-Rangel, F Maldonado, M Arroyo-Hernández, O Arrieta
BACKGROUND: Radiation pneumonitis (RP) is a frequent complication of concurrent chemoradiotherapy (CCRT) and is associated with severe symptoms that decrease quality of life and might result in pulmonary fibrosis or death. The aim of this study is to identify whether pulmonary function test (PFT) abnormalities may predict RP in non-small cell lung cancer (NSCLC) patients. METHODS: A prospective multi-institutional study was conducted with locally advanced and oligometastatic NSCLC patients...
April 24, 2018: Respiratory Research
https://www.readbyqxmd.com/read/29687665/effect-of-continuous-positive-airway-pressure-on-breathing-variability-in-early-preterm-lung-disease
#15
Emanuela Zannin, Chiara Veneroni, Raffaele L Dellacà, Roberta Corbetta, Bela Suki, Paolo E Tagliabue, Maria L Ventura
OBJECTIVES: In preterm infants, the application of nasal Continuous Positive Airway Pressure (nCPAP) improves lung function through several mechanisms and may interact with the control of breathing. Our aim was to evaluate the effect of increasing/decreasing nCPAP on gas exchange, breathing pattern, and its variability in preterm infants. METHODS: Fifeteen infants with mild to moderate respiratory distress syndrome (RDS) were studied on the first day of life. Infants had a mean (SD) gestational age of 30 + 4 (3 + 4) weeks + day and body weight of 1405 (606) g...
April 23, 2018: Pediatric Pulmonology
https://www.readbyqxmd.com/read/29687617/noninvasive-assessment-of-autonomic-function-in-human-neonates-born-at-the-extremes-of-fetal-growth-spectrum
#16
Hasthi U Dissanayake, Rowena L McMullan, Adrienne Gordon, Ian D Caterson, David S Celermajer, Melinda Phang, Camille Raynes-Greenow, Michael R Skilton, Jaimie W Polson
Birth weight is associated with adult cardiovascular disease, such that those at both ends of the spectrum are at increased risk. This may be driven in part by modification to autonomic control, a mechanistic contributor to hypertension. However, birth weight is a relatively crude surrogate of fetal growth; and newborn body composition may more accurately identify the "at risk" infant. Accordingly, we sought to determine whether newborns with high or low body fat have altered autonomic control of vasomotor function and cardiac contractility...
April 2018: Physiological Reports
https://www.readbyqxmd.com/read/29686742/time-to-exhale-additional-value-of-expiratory-chest-ct-in-chronic-obstructive-pulmonary-disease
#17
Joshua Gawlitza, Frederik Trinkmann, Hans Scheffel, Andreas Fischer, John W Nance, Claudia Henzler, Nils Vogler, Joachim Saur, Ibrahim Akin, Martin Borggrefe, Stefan O Schoenberg, Thomas Henzler
Objectives: Diagnostic guidelines for chronic obstructive pulmonary disease (COPD) are based on spirometry and clinical criteria. However, this does not address the pathophysiological complexity of the disease sufficiently. Until now, inspiratory chest computed tomography (CT) has been considered as the preferred imaging method in these patients. We hypothesized that expiratory CT may be superior to demonstrate pathophysiological changes. The aim of this prospective study was to systematically compare lung function tests with quantified CT parameters in inspiration and expiration...
2018: Canadian Respiratory Journal: Journal of the Canadian Thoracic Society
https://www.readbyqxmd.com/read/29679681/inhibition-of-protein-kinase-a-and-girk-channel-reverses-fentanyl-induced-respiratory-depression
#18
Xiaonan Liang, Zheng Yong, Ruibin Su
Opioid-induced respiratory depression is a major obstacle to improving the clinical management of moderate to severe chronic pain. Opioids inhibit neuronal activity via various pathways, including calcium channels, adenylyl cyclase, and potassium channels. Currently, the underlying molecular pathway of opioid-induced respiratory depression is only partially understood. This study aimed to investigate the mechanisms of opioid-induced respiratory depression in vivo by examining the effects of different pharmacological agents on fentanyl-induced respiratory depression...
April 18, 2018: Neuroscience Letters
https://www.readbyqxmd.com/read/29672184/oral-supplementation-with-beta-hydroxy-beta-methylbutyrate-arginine-and-glutamine-improves-lean-body-mass-in-healthy-older-adults
#19
Amy C Ellis, Gary R Hunter, Amy M Goss, Barbara A Gower
Oral intake of beta-hydroxy-beta-methylbutyrate (HMB), arginine, and glutamine may ameliorate muscle loss by stimulating protein synthesis and decreasing protein degradation while simultaneously decreasing inflammation. Previous studies provide evidence for improvement in body composition with dietary supplementation of these ingredients among patients with muscle-wasting diseases. The objectives of this study were to examine the effects of this amino acid mixture on lean body mass, muscle volume, and physical function among healthy older adults...
April 19, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29659955/accretion-of-fat-free-mass-rather-than-fat-mass-in-infancy-is-positively-associated-with-linear-growth-in-childhood
#20
Bitiya Admassu, Christian Ritz, Jonathan C K Wells, Tsinuel Girma, Gregers S Andersen, Tefera Belachew, Victor Owino, Kim F Michaelsen, Mubarek Abera, Rasmus Wibaek, Henrik Friis, Pernille Kæstel
Background: We have previously shown that fat-free mass (FFM) at birth is associated with height at 2 y of age in Ethiopian children. However, to our knowledge, the relation between changes in body composition during early infancy and later linear growth has not been studied. Objective: This study examined the associations of early infancy fat mass (FM) and FFM accretion with linear growth from 1 to 5 y of age in Ethiopian children. Methods: In the infant Anthropometry and Body Composition (iABC) study, a prospective cohort study was carried out in children in Jimma, Ethiopia, followed from birth to 5 y of age...
April 1, 2018: Journal of Nutrition
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