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impulse oscillometry

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https://www.readbyqxmd.com/read/28197800/small-airway-obstruction-in-chronic-obstructive-pulmonary-disease-potential-parameters-for-early-detection
#1
Tomasz Piorunek, Magdalena Kostrzewska, Marta Stelmach-Mardas, Marcin Mardas, Sławomir Michalak, Joanna Goździk-Spychalska, Halina Batura-Gabryel
The impulse oscillometry (IOS) is recognized as a complementary method to spirometry in the diagnostics of obstructive pulmonary disorders. The IOS enables to measure total respiratory resistance (R5) and proximal respiratory resistance (R20), with the R5-R20 difference reflecting small airway resistance. This study seeks to evaluate the usefulness of R5-R20, maximal mid-expiratory flow (MMEF), and forced expiratory volume in 3 s/forced vital capacity ratio (FEV3/FVC), in the assessment of small airway obstruction in chronic obstructive pulmonary disease (COPD)...
February 15, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28114141/lung-function-in-women-with-idiopathic-central-precocious-puberty-a-pilot-study%C3%A2
#2
Virginia Murri, Franco Antoniazzi, Michele Piazza, Paolo Cavarzere, Claudia Banzato, Attilio Boner, Rossella Gaudino
BACKGROUND: Studies have reported that women with early menarche (≤10 years) have lower lung function. AIM: To investigate lung function in women with a history of idio pathic central precocious puberty (ICPP) treated during childhood with gonadotropin-releasing hormone agonist (GnRHa). METHODS: ICPP women (n = 23) were compared with healthy age-matched controls (n = 23). Subjects were clinically evaluated by means of a questionnaire, baseline and post-β<Sub>2</Sub> agonist spirometry, impulse oscillometry (a measure of airway resistance), and measurement of fractional exhaled nitric oxide (FeNO)...
January 23, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/27932874/bronchodilator-response-of-advanced-lung-function-parameters-depending-on-copd-severity
#3
Linnea Jarenbäck, Göran Eriksson, Stefan Peterson, Jaro Ankerst, Leif Bjermer, Ellen Tufvesson
BACKGROUND: COPD is defined as partly irreversible airflow obstruction. The response pattern of bronchodilators has not been followed in advanced lung function parameters. PURPOSE: The aim of this study was to investigate bronchodilator response pattern in advanced lung function parameters in a continuous fashion along forced expiratory volume in 1 second (FEV1) percent predicted (%p) in COPD patients and controls. PATIENTS AND METHODS: Eighty-one smokers/ex-smokers (41 controls and 40 COPD) performed spirometry, body plethysmography, impulse oscillometry and single-breath helium dilution carbon monoxide diffusion at baseline, after salbutamol inhalation and then after an additional inhalation of ipratropium...
2016: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/27856329/airway-reactivity-in-response-to-repeated-emotional-film-clip-presentation-in-asthma
#4
Thomas Janssens, Ashton M Steele, David Rosenfield, Thomas Ritz
Emotional stimuli elicit airway constriction in individuals with asthma and in healthy individuals, but little is known about effects of repeated stimulation. We therefore explored the effect of repeated emotion induction on respiratory resistance (Rrs) using unpleasant, high-arousal surgery films and investigated effects of respiration and emotional reactivity. Twenty-six participants (13 with asthma) watched a series of 12 short, 45-s surgery films followed by 2-min recovery periods. Rrs assessed with impulse oscillometry was significantly elevated during films in both groups compared to baseline and recovered quickly after that...
November 14, 2016: Biological Psychology
https://www.readbyqxmd.com/read/27852080/prevalence-of-small-airway-dysfunction-among-copd-patients-with-different-gold-stages-and-its-role-in-the-impact-of-disease
#5
Ernesto Crisafulli, Roberta Pisi, Marina Aiello, Matteo Vigna, Panagiota Tzani, Anna Torres, Giuseppina Bertorelli, Alfredo Chetta
BACKGROUND: In chronic obstructive pulmonary disease (COPD) patients, small-airway dysfunction (SAD) is considered a functional hallmark of disease. However, the exact role of SAD in the clinical presentation of COPD is not yet completely understood; moreover, it is not known whether SAD may have a relationship with the impact of disease. OBJECTIVES: To evaluate the prevalence of SAD among COPD patients categorized by the old and the new GOLD classification and to ascertain whether there is a relationship between SAD and impact of disease measured by the COPD Assessment Test (CAT) questionnaire...
2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/27825614/impulse-oscillometry-in-the-assessment-of-asthmatic-children-and-adolescents-from-a-narrative-to-a-systematic-review
#6
REVIEW
Karoliny Dos Santos, Lílian L Fausto, Paulo A M Camargos, Maicon R Kviecinski, Jane da Silva
Diagnosis and management of asthma often relies mostly on symptoms because spirometry is not always reliable in some age groups, such as preschoolers. It is unclear whether impulse oscillometry (IOS) can supplement or replace spirometry. Available reports suggest that IOS has been applied with success in asthmatic children and adolescents to assess exacerbations, level of control, severity and response to treatment in the short and long term. Very few studies using adequate sample sizes and methods have been performed comparing the accuracy of IOS to spirometry for the diagnosis of asthma...
September 28, 2016: Paediatric Respiratory Reviews
https://www.readbyqxmd.com/read/27792267/very-low-birthweight-bronchopulmonary-dysplasia-survivors-had-similar-cardiac-outcomes-to-controls-at-six-years-to-14-years-of-age
#7
Piia Suursalmi, Anneli Eerola, Tuija Poutanen, Päivi Korhonen, Tarja Kopeli, Outi Tammela
AIM: This study evaluated cardiac function and its associations with lung function and neonatal pulmonary morbidity in very low birthweight (VLBW) children, with and without severe radiographic bronchopulmonary dysplasia (radBPD), at school age. METHODS: We examined 18 VLBW children with radBPD, 17 VLBW children without radBPD and 18 healthy term-born children using conventional echocardiography, tissue Doppler imaging, speckle tracking echocardiography and real-time three-dimensional echocardiography at six years to 14 years of age...
February 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/27743492/respiratory-reactance-in-children-aged-three-to-five%C3%A2-years-with-postinfectious-bronchiolitis-obliterans-is-higher-than-in-those-with-asthma
#8
Eun Lee, Jisun Yoon, Hyun-Ju Cho, Soo-Jong Hong, Jinho Yu
AIM: We investigated airway function in preschoolers with postinfectious bronchiolitis obliterans (PIBO) using impulse oscillometry (IOS). METHODS: This study enrolled 182 children aged three to five years: 12 with PIBO, 135 with asthma and 35 nonatopic controls. Respiratory resistance and reactance were assessed using IOS. RESULTS: The percentage predicted (% predicted) of prebronchodilator respiratory resistance at 5 Hz was significantly higher in children with PIBO (177...
January 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/27736034/sensitivity-of-newly-defined-impulse-oscillometry-indices-in-preschool-children
#9
Hanna Knihtilä, Anne Kotaniemi-Syrjänen, Anna S Pelkonen, Satu Kalliola, Mika J Mäkelä, L Pekka Malmberg
INTRODUCTION: Early origins of chronic obstructive pulmonary disease have been recognized. Impulse oscillometry (IOS) is suitable for assessment of lung function also in preschool children, and some novel indices have been connected to assessment of small airway function. However, limited data exist on the sensitivity of these new indices to detect lung function deficits in young symptomatic children. METHODS: IOS measurements of 103 healthy preschool children were evaluated to establish reference equations for the difference between respiratory resistance at 5 and 20 Hz (R5-20), the relative difference of R5-20 (R5-20%), and area under the reactance curve (AX)...
October 13, 2016: Pediatric Pulmonology
https://www.readbyqxmd.com/read/27718262/a-12-week-randomized-parallel-group-proof-of-concept-study-of-tulobuterol-patch-and-salmeterol-inhaler-as-add-on-therapy-in-adult-onset-mild-to-moderate-asthma
#10
Hideki Inoue, Akio Niimi, Hisako Matsumoto, Isao Ito, Tsuyoshi Oguma, Kojiro Otsuka, Tomoshi Takeda, Hitoshi Nakaji, Tomoko Tajiri, Toshiyuki Iwata, Tadao Nagasaki, Michiaki Mishima
Patch formulation of tulobuterol has been used in asthma treatment as a long-acting β2 -agonist (LABA) through sustained skin absorption. Its treatment efficacy, especially in small airways, remains poorly understood. The study aim was to investigate LABA add-on effects of tulobuterol patch (TP) and salmeterol inhaler (SA) on pulmonary function, asthma control and health status. Patients who had adult-onset under-control asthma, despite taking inhaled corticosteroids, were enrolled in a randomized, open-label, parallel-group, proof-of-concept study of 12-week add-on treatment with TP (n=16) or SA (n=17)...
January 2017: Clinical and Experimental Pharmacology & Physiology
https://www.readbyqxmd.com/read/27717725/airway-tone-dysfunction-among-pre-schoolers-with-positive-asthma-predictive-index-a-case-control-study
#11
V Lezana, A Gajardo, L Bofill, M Gutierrez, S Mora, J A Castro-Rodriguez
OBJECTIVE: To measure lung function by impulse oscillometry (IOS) and spirometry in recurrent wheezer pre-schoolers according to their asthma predictive index (API) condition. METHODS: We performed a case-control study enrolling all pre-schoolers with recurrent wheezing episodes (>3 episodes confirmed by physician) who presented at a paediatric pulmonology clinic. The population was divided according to stringent API criteria into positive or negative. RESULTS: In the nine-month period, 109 pre-schoolers were enrolled...
October 4, 2016: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27606596/study-on-small-airway-function-in-asthmatics-with-fractional-exhaled-nitric-oxide-and-impulse-oscillometry
#12
Lin Liu, Wen Liu, Chunhong Liu, Dexiang Wang, Jiping Zhao, Junfei Wang, Jinxiang Wu, Tian Liu, Yuanyuan Zhang, Yahui Liu, Liuzhao Cao, Liang Dong
INTRODUCTION AND OBJECTIVES: The invasive techniques can be direct and objective to assess small airway function, but they have significant risks and inconveniences for patients and can not be repeated often. Some sophisticated techniques such as fractional exhaled nitric oxide (FeNO) and impulse oscillometry (IOS) may surmount such restrictions. Therefore, we investigated the relation among FeNO, IOS and small airway function in asthmatic patients. METHODS: We recruited 140 asthmatic patients including 69 patients with small airway normal function and 71 patients with small airway dysfunction...
September 8, 2016: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/27592280/diagnostic-value-of-a-pattern-of-exhaled-breath-condensate-biomarkers-in-asthmatic-children
#13
I Maloča Vuljanko, M Turkalj, B Nogalo, S Bulat Lokas, D Plavec
BACKGROUND: Diagnosing asthma in children is a challenge and using a single biomarker from exhaled breath condensate (EBC) showed the lack of improvement in it. OBJECTIVE: The aim of this study was to assess the diagnostic potential of a pattern of simple chemical biomarkers from EBC in diagnosing asthma in children in a real-life setting, its association with lung function and gastroesophageal reflux disease (GERD). METHODS: In 75 consecutive children aged 5-7 years with asthma-like symptoms the following tests were performed: skin prick tests, spirometry, impulse oscillometry (IOS), exhaled NO (FENO), 24-hour oesophageal pH monitoring and EBC collection with subsequent analysis of pH, carbon dioxide tension, oxygen tension, and concentrations of magnesium, calcium, iron and urates...
January 2017: Allergologia et Immunopathologia
https://www.readbyqxmd.com/read/27578934/impulse-oscillometry-the-state-of-art-for-lung-function-testing
#14
REVIEW
Koundinya Desiraju, Anurag Agrawal
Impulse oscillometry (IOS) is a variant of forced oscillation technique, described by Dubois over 50 years ago, which permits passive measurement of lung mechanics. In this method, sound waves are superimposed on normal tidal breathing, and the disturbances in flow and pressure caused by the external waves are used to calculate parameters describing the resistance to airflow and reactive parameters that mostly relate to efficient storage and return of energy by the lung. It requires minimal patient cooperation and can be done easily in subjects who are unable to perform spirometry...
July 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27549623/receiver-operating-characteristics-of-impulse-oscillometry-parameters-for-predicting-obstructive-sleep-apnea-in-preobese-and-obese-snorers
#15
Arikin Abdeyrim, Liang Tang, Arzugl Muhamat, Kelimu Abudeyrim, YongPing Zhang, NanFang Li, Yinchun Wang, Minghua Zhao
BACKGROUND: Inability to maintain upper-airway patency during sleep is a cause of obstructive sleep apnea (OSA) and its sequelae. The associated syndrome (OSAS) is common in obese populations, currently, nocturnal polysomnography is the gold standard for diagnosing this conditions, but the diagnostic procedures are expensive and time-consuming. Therefore, identification of new markers of OSAS would be useful. This study aims to examine the receiver operating characteristics of impulse oscillometry (IOS) parameters for the prediction of OSAS in preobese and obese snoring patients...
August 22, 2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27527645/sleep-and-pulmonary-outcomes-for-clinical-trials-of-airway-plexiform-neurofibromas-in-nf1
#16
Scott R Plotkin, Stephanie D Davis, Kent A Robertson, Srivandana Akshintala, Julian Allen, Michael J Fisher, Jaishri O Blakeley, Brigitte C Widemann, Rosalie E Ferner, Carole L Marcus
OBJECTIVE: Plexiform neurofibromas (PNs) are complex, benign nerve sheath tumors that occur in approximately 25%-50% of individuals with neurofibromatosis type 1 (NF1). PNs that cause airway compromise or pulmonary dysfunction are uncommon but clinically important. Because improvement in sleep quality or airway function represents direct clinical benefit, measures of sleep and pulmonary function may be more meaningful than tumor size as endpoints in therapeutic clinical trials targeting airway PN...
August 16, 2016: Neurology
https://www.readbyqxmd.com/read/27527123/development-of-a-semiquantitative-histological-score-for-the-diagnosis-of-heaves-using-endobronchial-biopsy-specimens-in-horses
#17
M Bullone, P Hélie, P Joubert, J-P Lavoie
BACKGROUND: Remodeling of the peripheral airways persists during the asymptomatic phase of heaves. Assessing the histology of large bronchi could facilitate the diagnosis of heaves during remission of the disease. HYPOTHESIS: Airway inflammation and remodeling in endobronchial biopsy (EBB) specimens differentiate horses with heaves from controls, independently of their clinical status (exacerbation or remission). ANIMALS: Fourteen healthy horses and 24 horses with heaves...
September 2016: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/27516132/peripheral-bronchial-obstruction-evaluation-in-patients-with-asthma-by-lung-sound-analysis-and-impulse-oscillometry
#18
Terufumi Shimoda, Yasushi Obase, Yukio Nagasaka, Reiko Kishikawa, Hiroshi Mukae, Tomoaki Iwanaga
BACKGROUND: Computer-aided lung sound analysis (LSA) has been reported to be useful for evaluating airway inflammation and obstruction in asthma patients. We investigated the relation between LSA and impulse oscillometry with the evaluation of peripheral airway obstruction. METHODS: A total of 49 inhaled corticosteroid-naive bronchial asthma patients underwent LSA, spirometry, impulse oscillometry, and airway hyperresponsiveness testing. The data were analyzed to assess correlations between the expiration: inspiration lung sound power ratio (dB) at low frequencies between 100 and 195 Hz (E/I LF) and various parameters...
January 2017: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/27492518/clinical-characteristics-of-adult-asthma-associated-with-small-airway-dysfunction
#19
S Kjellberg, B K Houltz, O Zetterström, P D Robinson, Per M Gustafsson
Suboptimal asthma control is common despite modern asthma therapy. The degree of peripheral airway involvement remains unclear and poor medication delivery to these regions might be a contributing reason for this failure in obtaining adequate symptom control. A cohort of 196 adults (median (range) age 44 (18-61) years, 109 females, 54 ex-smokers, six current smokers) with physician-diagnosed asthma were recruited from primary care. Subjects were characterized clinically by interviews, questionnaires, skin prick tests (SPT) and blood eosinophil counts...
August 2016: Respiratory Medicine
https://www.readbyqxmd.com/read/27484107/impulse-oscillometry-and-spirometry-small-airway-parameters-in-mild-to-moderate-bronchiectasis
#20
Wei-Jie Guan, Jing-Jing Yuan, Yong-Hua Gao, Hui-Min Li, Jin-Ping Zheng, Rong-Chang Chen, Nan-Shan Zhong
BACKGROUND: Both impulse oscillometry and spirometry can reflect small-airway disorders. The objective of this work was to investigate the diagnostic value of impulse oscillometry and spirometry small-airway parameters and their correlation with radiology, disease severity, and sputum bacteriology in mild to moderate bronchiectasis (bronchiectasis severity index <9) and to validate these findings in sensitivity analyses (mild bronchiectasis). METHODS: We recruited 94 subjects with mild to moderate bronchiectasis and 26 healthy subjects...
November 2016: Respiratory Care
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