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https://www.readbyqxmd.com/read/28933714/hr-v-combining-dot-above-o2-and-rpe-relationships-in-an-aquatic-incremental-maximum-test-performed-by-young-women
#1
Gabriela B David, Luana S Andrade, Gustavo Z Schaun, Cristine L Alberton
David, GB, Andrade, LS, Schaun, GZ, and Alberton, CL. HR, V[Combining Dot Above]O2, and RPE relationships in an aquatic incremental maximum test performed by young women. J Strength Cond Res 31(10): 2852-2858, 2017-The purpose of the study was to verify the relationship between oxygen uptake (V[Combining Dot Above]O2), heart rate (HR), rate of perceived exertion (RPE), and cadence (CAD) in an aquatic incremental maximum test performed during a water-based stationary running exercise. The study also verified the best adjustments for these relationships (linear or polynomial)...
October 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28930921/sham-opioids-relieve-multidimensional-aspects-of-chronic-back-pain
#2
Luana Colloca
No abstract text is available yet for this article.
October 2017: Pain
https://www.readbyqxmd.com/read/28929971/medisyn-uncertainty-aware-visualization-of-multiple-biomedical-datasets-to-support-drug-treatment-selection
#3
Chen He, Luana Micallef, Zia-Ur-Rehman Tanoli, Samuel Kaski, Tero Aittokallio, Giulio Jacucci
BACKGROUND: Dispersed biomedical databases limit user exploration to generate structured knowledge. Linked Data unifies data structures and makes the dispersed data easy to search across resources, but it lacks supporting human cognition to achieve insights. In addition, potential errors in the data are difficult to detect in their free formats. Devising a visualization that synthesizes multiple sources in such a way that links between data sources are transparent, and uncertainties, such as data conflicts, are salient is challenging...
September 13, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/28925588/evaluation-of-the-effect-of-four-final-irrigation-protocols-on-root-canal-dentin-components-by-polarized-light-microscopy-and-scanning-electron-microscopy
#4
Flávia Emi Razera Baldasso, Luana Roleto Cardoso, Vinicius Duval da Silva, Renata Dornelles Morgental, Patrícia Maria Poli Kopper
The present study aimed to evaluate the effects of four endodontic chelating agents, followed by 2.5% sodium hypochlorite (NaOCl), as final irrigation regimens on organic and inorganic components of human root dentin. Sixty mandibular incisors were prepared and randomly divided into six groups (n = 10): QMiX, 1% peracetic acid (PA), 17% EDTA, 10% citric acid (CA), 2.5% NaOCl (solution control) and distilled water (DW-negative control). After irrigation with the chelating agents, a final flush was performed with 2...
September 19, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28922309/quantifying-the-physiological-stress-response-to-simulated-maritime-pilotage-tasks-the-influence-of-task-complexity-and-pilot-experience
#5
Luana C Main, Alexander Wolkow, Timothy P Chambers
OBJECTIVE: The aim of this study was to quantify the stress associated with performing maritime pilotage tasks in a high-fidelity simulator. METHODS: Eight trainee and 13 maritime pilots completed two simulated pilotage tasks of varying complexity. Salivary cortisol samples were collected pre- and post-simulation for both trials. Heart rate was measured continuously throughout the study. RESULTS: Significant changes in salivary cortisol (P = 0...
September 15, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28920405/effects-of-processing-particle-size-and-moisturizing-of-sorghum-based-feeds-on-pellet-quality-and-broiler-production
#6
Patrícia Garcia Silva, Fabiana Ramos Santos, Luana Martins Schaly Oliveira, Nayanne Rodrigues Oliveira, Fábio Ataides Moura Júnior, Maura Regina Sousa Silva, Deibity Alves Cordeiro, Cibele Silva Minafra
Objective: This study aimed to assess the effect of pelleted and expanded sorghum-based feeds prepared with different moisture levels and particle size of ingredients on metabolizable energy, ileal digestibility of amino acids and broiler performance. Methods: The experiment was performed with 720 male broiler chicks of the Cobb strain, with treatments of six replications, with 15 birds each; they were arranged in a completely randomized design and 2 × 2 × 2 factorial scheme (pelleted or expanded feed processing, 0...
September 18, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28900795/haptoglobin-levels-but-not-hp1-hp2-polymorphism-are-associated-with-polycystic-ovary-syndrome
#7
Laura M L Carvalho, Cláudia N Ferreira, Daisy K D de Oliveira, Kathryna F Rodrigues, Rita C F Duarte, Márcia F A Teixeira, Luana B Xavier, Ana Lúcia Candido, Fernando M Reis, Ieda F O Silva, Fernanda M F Campos, Karina B Gomes
PURPOSE: Proteomic studies suggest an association between haptoglobin (Hp) and polycystic ovary syndrome (PCOS). Hp is a classic inflammatory marker and binds to the intravascular hemoglobin, avoiding the oxidative damages that can be caused by free hemoglobin. Inflammation and oxidative stress are important in the pathogenesis of the PCOS, one of the most frequent metabolic diseases in women. METHODS: To validate these proteomic studies, we developed a controlled cross-sectional study that aimed to evaluate the Hp levels and allelic and genotypic frequencies of Hp1-Hp2 polymorphism in Brazilian women with PCOS...
September 13, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/28895933/higher-protein-intake-does-not-improve-lean-mass-gain-when-compared-with-rda-recommendation-in-postmenopausal-women-following-resistance-exercise-protocol-a-randomized-clinical-trial
#8
Luana T Rossato, Paula C Nahas, Flávia M S de Branco, Fernanda M Martins, Aletéia P Souza, Marcelo A S Carneiro, Fábio L Orsatti, Erick P de Oliveira
The aim of this study was to evaluate the effect of a higher protein intake on lean body mass (LBM) gain in postmenopausal women practicing resistance exercise and compare it to the Recommended Dietary Allowance (RDA) recommendation. Twenty-three postmenopausal women (63.2 ± 7.8 years) were randomized into two groups. The group with higher protein intake (n = 11) (HP) received a dietary plan with ~1.2 g·kg(-1)·day(-1) of protein, while the normal protein (NP) group (n = 12) was instructed to ingest ~0.8 g·kg(-1)·day(-1) of protein (RDA recommendation)...
September 12, 2017: Nutrients
https://www.readbyqxmd.com/read/28895244/identification-and-characterization-of-three-novel-mutations-in-the-casq1-gene-in-four-patients-with-tubular-aggregate-myopathy
#9
Virginia Barone, Valeria Del Re, Alessandra Gamberucci, Valentina Polverino, Lucia Galli, Daniela Rossi, Elisa Costanzi, Luana Toniolo, Gianna Berti, Alessandro Malandrini, Giulia Ricci, Gabriele Siciliano, Gaetano Vattemi, Giuliano Tomelleri, Enrico Pierantozzi, Simone Spinozzi, Nila Volpi, Rosella Fulceri, Roberto Battistutta, Carlo Reggiani, Vincenzo Sorrentino
Here we report the identification of three novel missense mutations in the calsequestrin-1 (CASQ1) gene in four patients with tubular aggregate myopathy. These CASQ1 mutations affect conserved amino acids in position 44 (p.(Asp44Asn)), 103 (p.(Gly103Asp)) and 385 (p.(Ile385Thr)). Functional studies, based on turbidity and dynamic light scattering measurements at increasing Ca(2+) concentrations, showed a reduced Ca(2+) -dependent aggregation for the CASQ1 protein containing p.Asp44Asn and p.Gly103Asp mutations and a slight increase in Ca(2+) -dependent aggregation for the p...
September 11, 2017: Human Mutation
https://www.readbyqxmd.com/read/28892741/effect-of-diet-with-omega-3-in-basal-brain-electrical-activity-and-during-status-epilepticus-in-rats
#10
Daniella Tavares Pessoa, Eva Luana Almeida da Silva, Edbhergue Ventura Lola Costa, Romildo Albuquerque Nogueira
Western diets are high in saturated fat and low in omega-3. Certain animals cannot produce omega-3 from their own lipids, making it necessary for it to be acquired from the diet. However, omega-3s are important components of the plasma membrane, and altering their proportions can promote physical and chemical alterations in the membranes, which may modify neuronal excitability. These alterations occur in healthy individuals, as well as in patients with epilepsy who are more sensitive to changes in brain electrical activity...
September 1, 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28888015/functionalization-of-titanium-dioxide-nanotubes-with-biomolecules-for-biomedical-applications
#11
REVIEW
Weslley F Oliveira, Isabel R S Arruda, Germana M M Silva, Giovanna Machado, Luana C B B Coelho, Maria T S Correia
Titanium (Ti) and its alloys are extensively used in the manufacture of implants because they have biocompatibility. The production of a nanostructured surface can be achieved by means of titanium dioxide nanotubes (TNTs) which can have dimensions equivalent to the nanometric components of human bone, in addition to increasing the efficiency of such implants. The search is ongoing for ways to improve the performance of these TNTs in terms of their functionalization through coating these nanotubular matrices with biomolecules...
December 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28883019/suppression-of-striatal-prediction-errors-by-the-prefrontal-cortex-in-placebo-hypoalgesia
#12
Lieven A Schenk, Christian Sprenger, Selim Onat, Luana Colloca, Christian Büchel
Classical learning theories predict extinction after discontinuation of reinforcement through prediction errors. However, placebo hypoalgesia, although mediated by associative learning, has been shown to be resistant to extinction. We tested the hypothesis that this is mediated by suppression of prediction error processing through the prefrontal cortex (PFC). We compared pain modulation through treatment cues (placebo hypoalgesia, treatment context) with pain modulation through stimulus intensity cues (stimulus context) during functional magnetic resonance imaging in 48 male and female healthy volunteers...
September 7, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28878606/major-contribution-of-genomic-copy-number-variation-in-syndromic-congenital-heart-disease-the-use-of-mlpa-as-the-first-genetic-test
#13
Rejane A C Monteiro, Mariana L de Freitas, Gabrielle S Vianna, Valdirene T de Oliveira, Rafaella X Pietra, Luana C A Ferreira, Patrícia P O Rocha, Michele da S Gonçalves, Giovana da C César, Joziele de S Lima, Paula F V Medeiros, Juliana F Mazzeu, Fernanda S Jehee
Congenital heart disease (CHD) is the most common congenital disorder among live births. When associated with extracardiac abnormalities, it is characterized as a syndromic heart disease (syndromic CHD) and corresponds to 25% of all liveborn infants with a heart defect. The etiology in about 65% of the cases still remains unknown, and in about 35% of the patients, it is associated with genetic factors. In the present study, MLPA and SNP-array techniques were used to investigate a group of 47 patients with syndromic CHD...
August 2017: Molecular Syndromology
https://www.readbyqxmd.com/read/28875471/optimization-of-curcuma-oil-quinine-loaded-nanocapsules-for-malaria-treatment
#14
Graziela Scheuer Gomes, Tamara Ramos Maciel, Eduarda Martini Piegas, Luana Roberta Michels, Letícia Marques Colomé, Rodrigo José Freddo, Daiana Silva de Ávila, Andre Gundel, Sandra Elisa Haas
Quinine, a treatment used in chloroquine-resistant falciparum malaria, was loaded into poly(ɛ-caprolactone) or Eudragit(®) RS100 nanocapsules using Curcuma oil as the oil-based core. Until now, the effect of cationic nanocapsules on malaria has not been reported. A 2(4) factorial design was adopted using, as independent variables, the concentration of Curcuma oil, presence of quinine, type of polymer, and aqueous surfactant. Diameter, zeta potential, and pH were the responses studied. The formulations were also evaluated for drug content, encapsulation efficiency, photostability, and antimalarial activity against Plasmodium berghei-infected mice...
September 5, 2017: AAPS PharmSciTech
https://www.readbyqxmd.com/read/28874604/mitochondrial-redox-signaling-enables-repair-of-injured-skeletal-muscle-cells
#15
Adam Horn, Jack H Van der Meulen, Aurelia Defour, Marshall Hogarth, Sen Chandra Sreetama, Aaron Reed, Luana Scheffer, Navdeep S Chandel, Jyoti K Jaiswal
Strain and physical trauma to mechanically active cells, such as skeletal muscle myofibers, injures their plasma membranes, and mitochondrial function is required for their repair. We found that mitochondrial function was also needed for plasma membrane repair in myoblasts as well as nonmuscle cells, which depended on mitochondrial uptake of calcium through the mitochondrial calcium uniporter (MCU). Calcium uptake transiently increased the mitochondrial production of reactive oxygen species (ROS), which locally activated the guanosine triphosphatase (GTPase) RhoA, triggering F-actin accumulation at the site of injury and facilitating membrane repair...
September 5, 2017: Science Signaling
https://www.readbyqxmd.com/read/28873766/occurrence-and-phenotypic-and-molecular-characterization-of-listeriamonocytogenes-and-salmonella-spp-in-slaughterhouses-in-southern-brazil
#16
Mariana Almeida Iglesias, Isabela Schneid Kroning, Luana Tombini Decol, Bernadette Dora Gombossy de Melo Franco, Wladimir Padilha da Silva
This study addressed the occurrence of Listeriamonocytogenes and Salmonella spp. in bovine carcasses at two slaughterhouses in southern Brazil. Then, the antimicrobial susceptibility profile and the virulence potential of the isolates were evaluated. Two hundred carcasses were sampled at four steps of the slaughter process, with L. monocytogenes being isolated in 12 and Salmonella spp. in 17 carcasses. All L. monocytogenes isolates carried the hlyA, prfA, plcA, plcB, actA, iap, mpl, inlA, inlB, inlC, and inlJ genes, while Salmonella spp...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28873749/annatto-carotenoids-attenuate-oxidative-stress-and-inflammatory-response-after-high-calorie-meal-in-healthy-subjects
#17
Miguel Roehrs, Lisiane Conte, Dariane Trivisiol da Silva, Thiago Duarte, Luana Haselein Maurer, José Antonio Mainardi de Carvalho, Rafael Noal Moresco, Sabrina Somacal, Tatiana Emanuelli
The aim of this study was to evaluate the effect of annatto carotenoids intake associated to a single high-calorie meal (high fat and high carbohydrate) in postprandial biochemical, inflammatory and oxidative stress markers. Twelve healthy subjects (6 men, 6 women) were included in this randomised, controlled crossover study. Baseline blood samples were collected from fasting subjects that immediately received high-calorie meal without carotenoid (placebo) or containing 1.2mg/kg bixin (BIX) or 0.06mg/kg norbixin (NBIX)...
October 2017: Food Research International
https://www.readbyqxmd.com/read/28869960/syncytia-induction-by-clinical-isolates-of-human-respiratory-syncytial-virus-a
#18
Talita Bianca Gagliardi, Miriã Ferreira Criado, José Luiz Proença-Módena, Ariane Mirela Saranzo, Marisa Akiko Iwamoto, Flávia Escremim de Paula, Ricardo Souza Cardoso, Luana Sela Delcaro, Maria Lúcia Silva, Ataide Ademir Câmara, Eurico Arruda
OBJECTIVE: Syncytia formation is the hallmark of the cytopathic effect caused by human respiratory syncytial virus (HRSV), which is the most important viral respiratory pathogen in children. This article reports methodological improvements in primary HRSV isolation and the importance of syncytia formation and mRNA levels of F protein for the progeny yield, using clinical isolates of HRSV. METHODS: The A and B strains of HRSV were isolated in HEp-2 cell cultures from fresh and frozen nasopharyngeal aspirates...
September 5, 2017: Intervirology
https://www.readbyqxmd.com/read/28867645/5-fluorouracil-induces-inflammation-and-oxidative-stress-in-the-major-salivary-glands-affecting-salivary-flow-and-saliva-composition
#19
Luana E Bomfin, Cíntia M Braga, Thais A Oliveira, Conceição S Martins, Danielle A Foschetti, Ana A Q A Santos, Deiziane V S Costa, Renata F C Leitão, Gerly A C Brito
This study aimed to elucidate the effect of 5-fluorouracil (5-FU) on the histological aspects of the major salivary glands, salivary flow and saliva composition using an established oral mucositis model in hamsters. Oral mucositis was induced by two intraperitoneal administrations of 5-FU in two consecutive days (60 and 40mg/kg), followed by cheek pouch mucosa scratch, on day 4. The Pilocarpine-stimulated salivary flow was measured 4 and 10days after the first 5-FU injection. Salivary glands were harvested for histopathological analysis, measurement of inflammatory cells, quantification of pro-inflammatory cytokines (TNF-α and IL-1β), investigation of cell death and cell proliferation...
September 1, 2017: Biochemical Pharmacology
https://www.readbyqxmd.com/read/28865353/mechanisms-involved-in-facial-heat-hyperalgesia-induced-by-endothelin-1-in-female-rats
#20
Rafael Fernandes de Souza, Luana Lechenakoski de Oliveira, Carina Fernanda Mattedi Nones, Renata Cristiane Dos Reis, Erika Ivanna Araya, Caroline Machado Kopruszinski, Giles Alexander Rae, Juliana Geremias Chichorro
OBJECTIVE: Pronociceptive responses to endothelins in the trigeminal system seem to be mediated by ETA and ETB receptors, which have been shown to be expressed in neurons of the trigeminal ganglion of humans and rats. The present study aimed to evaluate the ability of endothelin-1 (ET-1) to induce facial heat hyperalgesia in female rats, the contribution of ETA and ETB receptors to this response, as well as the mechanisms underlying heat hyperalgesia induced by ET-1. DESIGN: ET-1 (100pmol/50μL) was injected into the upper lip and heat hyperalgesia was evaluated for up to 6h...
August 30, 2017: Archives of Oral Biology
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