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https://www.readbyqxmd.com/read/28239369/plant-growth-promoting-bacteria-associated-with-langsdorffia-hypogaea-rhizosphere-host-biological-interface-a-neglected-model-of-bacterial-prospection
#1
Érica B Felestrino, Iara F Santiago, Luana da Silva Freitas, Luiz H Rosa, Sérvio P Ribeiro, Leandro M Moreira
Soil is a habitat where plant roots and microorganisms interact. In the region of the Brazilian Iron Quadrangle (IQ), studies involving the interaction between microbiota and plants have been neglected. Even more neglected are the studies involving the holoparasite plant Langsdorffia hypogaea Mart. (Balanophoraceae). The geomorphological peculiarities of IQ soil, rich in iron ore, as well as the model of interaction between L. hypogaea, its hosts and the soil provide a unique niche that acts as selective pressure to the evolution of plant growth-promoting bacteria (PGPB)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28238802/phoneutria-nigriventer-spider-toxin-tx2-6-induces-priapism-in-mice-even-after-cavernosal-denervation
#2
Katherine Garcia Ravelli, Adriana de Toledo Ramos, Luana Baracho Gonçalves, Fábio Carlos Magnoli, Lanfranco Ranieri Paolo Troncone
The Phoneutria nigriventer spider toxin Tx2-6 causes priapism in humans and mice. This toxin produces a delay in Sodium channel inactivation, generalized vascular congestion and death by respiratory failure. NO-Synthase inhibitors seem to abolish toxin-induced priapism. The understanding of the ultimate molecular mechanism involved in toxin-induced priapism may shed light on aspects of erectile function/dysfunction. This study investigates if cavernosal denervation can abolish the toxin-induced priapism. Surgical cavernosal nerve excision/denervation was performed in mice and confirmed by infertility, histological assessment of fibrosis and immunohistochemical staining for synaptophysin...
February 24, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/28238682/association-between-dietary-pattern-and-cardiometabolic-risk-in-children-and-adolescents-a-systematic-review
#3
REVIEW
Naruna Pereira Rocha, Luana Cupertino Milagres, Giana Zarbato Longo, Andréia Queiroz Ribeiro, Juliana Farias de Novaes
OBJECTIVE: To evaluate the association between dietary patterns and cardiometabolic risk factors in children and adolescents. DATA SOURCE: This article followed the recommendations of PRISMA, which aims to guide review publications in the health area. The article search strategy included searches in the electronic databases MEDLINE via PubMed, Scopus, and LILACS. There was no date limitation for publications. The descriptors were used in English according to MeSH and in Portuguese according to DeCS...
February 23, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28231241/hydrocephalus-and-arthrogryposis-in-an-immunocompetent-mouse-model-of-zika-teratogeny-a-developmental-study
#4
Jose Xavier-Neto, Murilo Carvalho, Bruno Dos Santos Pascoalino, Alisson Campos Cardoso, Ângela Maria Sousa Costa, Ana Helena Macedo Pereira, Luana Nunes Santos, Ângela Saito, Rafael Elias Marques, Juliana Helena Costa Smetana, Silvio Roberto Consonni, Carla Bandeira, Vivian Vasconcelos Costa, Marcio Chaim Bajgelman, Paulo Sérgio Lopes de Oliveira, Marli Tenorio Cordeiro, Laura Helena Vega Gonzales Gil, Bianca Alves Pauletti, Daniela Campos Granato, Adriana Franco Paes Leme, Lucio Freitas-Junior, Carolina Borsoi Moraes Holanda de Freitas, Mauro Martins Teixeira, Estela Bevilacqua, Kleber Franchini
The teratogenic mechanisms triggered by ZIKV are still obscure due to the lack of a suitable animal model. Here we present a mouse model of developmental disruption induced by ZIKV hematogenic infection. The model utilizes immunocompetent animals from wild-type FVB/NJ and C57BL/6J strains, providing a better analogy to the human condition than approaches involving immunodeficient, genetically modified animals, or direct ZIKV injection into the brain. When injected via the jugular vein into the blood of pregnant females harboring conceptuses from early gastrulation to organogenesis stages, akin to the human second and fifth week of pregnancy, ZIKV infects maternal tissues, placentas and embryos/fetuses...
February 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28231160/sourdough-based-biotechnologies-for-the-production-of-gluten-free-foods
#5
REVIEW
Luana Nionelli, Carlo Giuseppe Rizzello
Sourdough fermentation, a traditional biotechnology for making leavened baked goods, was almost completely replaced by the use of baker's yeast and chemical leavening agents in the last century. Recently, it has been rediscovered by the scientific community, consumers, and producers, thanks to several effects on organoleptic, technological, nutritional, and functional features of cereal-based products. Acidification, proteolysis, and activation of endogenous enzymes cause several changes during sourdough fermentation, carried out by lactic acid bacteria and yeasts, which positively affect the overall quality of the baked goods...
September 20, 2016: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28225852/tryptophan-overloading-activates-brain-regions-involved-with-cognition-mood-and-anxiety
#6
Luana C A Silva, Milena B Viana, José S Andrade, Melyssa A Souza, Isabel C Céspedes, Vânia D'Almeida
Tryptophan is the only precursor of serotonin and mediates serotonergic activity in the brain. Previous studies have shown that the administration of tryptophan or tryptophan depletion significantly alters cognition, mood and anxiety. Nevertheless, the neurobiological alterations that follow these changes have not yet been fully investigated. The aim of this study was to verify the effects of a tryptophan-enriched diet on immunoreactivity to Fos-protein in the rat brain. Sixteen male Wistar rats were distributed into two groups that either received standard chow diet or a tryptophan-enriched diet for a period of thirty days...
February 16, 2017: Anais da Academia Brasileira de Ciências
https://www.readbyqxmd.com/read/28224907/multi-block-data-analysis-using-comdim-for-the-evaluation-of-complex-samples-characterization-of-edible-oils
#7
Larissa Naida Rosa, Luana Caroline de Figueiredo, Elton Guntendorfer Bonafé, Aline Coqueiro, Jesuí Vergílio Visentainer, Paulo Henrique Março, Douglas N Rutledge, Patrícia Valderrama
The ComDim chemometrics method for multi-block analysis was employed to evaluate thirty-two vegetable oil samples analyzed by near infrared (NIR) and ultraviolet-visible (UV-Vis) spectroscopy, and by Gas Chromatography with flame ionization detection (GC-FID) for their fatty acids composition. This unsupervised pattern recognition method was able to extract information from the tables of results that could be presented in informative graphs showing the relationship between the samples through the scores, the predominance of information in particular tables through the saliences and the contribution of the variables in each table which were responsible for the similarities observed in the samples, through the loadings plots...
April 8, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28222613/phytochemical-investigations-and-antiproliferative-secondary-metabolites-from-thymus-alternans-growing-in-slovakia
#8
Stefano Dall'Acqua, Gregorio Peron, Sara Ferrari, Valentina Gandin, Massimo Bramucci, Luana Quassinti, Pavol Mártonfi, Filippo Maggi
CONTEXT: Thymus alternans Klokov (Lamiaceae) is a neglected species of the genus Thymus (Sect. Serpyllum) endemic to Carpathian area, where it is used as a flavouring agent and for medicinal purposes. OBJECTIVE: The aim of the work was to identify antiproliferative constituents from the flowering aerial parts of this plant. MATERIALS AND METHODS: Thymus alternans extracts were analyzed by HPLC-MS(n) and subjected to extensive chromatographic separations...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28221886/technological-properties-and-biogenic-amines-production-by-bacteriocinogenic-lactococci-and-enterococci-strains-isolated-from-raw-goat-s-milk
#9
Luana Martins Perin, Simona Belviso, Barbara Dal Bello, Luís Augusto Nero, Luca Cocolin
Technological properties and biogenic amine production were analyzed in 56 bacteriocinogenic lactococci and enterococci strains isolated from raw goat's milk. Fifteen lactococci strains were able to reduce milk pH to 5.3 or lower after 6 h, while enterococci strains were initially slow in producing acids. Lactococcus lactis subsp. lactis GLc06 and three strains of Enterococcus faecalis (GEn20, GEn22, and GEn23) presented high proteolytic activity. L. lactis subsp. lactis GLc06 and E. faecalis GEn22 also showed a high percentage of autolysis after only 4 h, reaching 71...
January 2017: Journal of Food Protection
https://www.readbyqxmd.com/read/28220554/changes-in-stable-isotope-ratios-in-pdo-cheese-related-to-the-area-of-production-and-green-forage-availability-the-case-study-of-pecorino-siciliano
#10
Bernardo Valenti, Luisa Biondi, Luca Campidonico, Luana Bontempo, Giuseppe Luciano, Fortunato Di Paola, Venera Copani, Luca Ziller, Federica Camin
RATIONALE: No study has investigated the variations of stable isotope ratios (SIRs) of bioelements within a Protected Designations of Origin (PDO) cheese and few studies have focused on the dietary background of animals. For traceability purposes, it is important to know how and whether these issues affect SIRs in a PDO cheese. METHODS: Thirty-six Pecorino Siciliano cheese samples were collected in three east-Sicilian areas in seasons in which green herbage was present or absent in an animal's diet...
February 20, 2017: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/28212534/association-between-echocardiographic-structural-parameters-and-body-weight-in-wistar-rats
#11
Silvio A Oliveira-Junior, Paula F Martinez, William Y C Fan, Bruno T Nakatani, Luana U Pagan, Carlos R Padovani, Antonio C Cicogna, Marina P Okoshi, Katashi Okoshi
BACKGROUND: The association between echocardiographic structural parameters and body weight (BW) during rat development has been poorly addressed. We evaluated echocardiographic variables: left ventricular (LV) end-diastolic (LVDD) and end-systolic (LVSD) diameters, LV diastolic posterior wall thickness (PWT), left atrial diameter (LA), and aortic diameter (AO) in function of BW during development.Results/Materials and Methods: Male Wistar rats (n = 328, BW: 302-702 g) were retrospectively used to construct regression models and 95% confidence intervals relating to cardiac structural parameters and BW...
February 13, 2017: Oncotarget
https://www.readbyqxmd.com/read/28209096/increased-oxidative-stress-alters-nucleosides-metabolite-levels-in-sickle-cell-anemia
#12
Lívia Gelain Castilhos, Juliana Sorraila de Oliveira, Stephen Adeniyi Adefegha, Luana Pereira Magni, Pedro Henrique Doleski, Fatima Husein Abdalla, Cínthia Melazzo de Andrade, Daniela Bitencourt Rosa Leal
OBJECTIVES: This study was conducted to assess the markers of oxidative stress, myeloperoxidase (MPO), acetylcholinesterase (AChE) and xanthine oxidase (XO) activities as well as the levels of nucleotide metabolites in sickle cell anemia (SCA) patients. METHODS: Fifteen SCA treated patients and 30 health subjects (control group) were selected. The markers of oxidative stress (levels of reactive oxygen species (ROS), plasma proteins, carbonyl content, lipid peroxidation (TBARS), total thiols (T-SH), glutathione and catalase activity), MPO, AChE and XO activities as well as the levels of nucleotide metabolites were measured in SCA patients...
February 16, 2017: Redox Report: Communications in Free Radical Research
https://www.readbyqxmd.com/read/28207286/lc-ms-ms-simultaneous-analysis-of-allopregnanolone-epiallopregnanolone-pregnanolone-dehydroepiandrosterone-and-dehydroepiandrosterone-3-sulfate-in-human-plasma
#13
Luana Lionetto, Fernando De Andrés, Matilde Capi, Martina Curto, Donata Sabato, Maurizio Simmaco, Paola Bossù, Eleonora Sacchinelli, Maria Donata Orfei, Federica Piras, Nerisa Banaj, Gianfranco Spalletta
AIM: Several neuropsychopharmacological properties have been attributed to the 3α-reduced pregnane steroids, allopregnanolone and pregnanolone, as well as to dehydroepiandrosterone sulfate because of their ability to modulate γ-aminobutyric acid (GABAA) receptors in the CNS. In order to understand better their role in several mechanisms in CNS, a new methodology is proposed to monitor these compounds in human plasma. Methodology & results: The analytes were first derivatized with 2-hydrazinopyridine and extracted from plasma using SPE...
February 16, 2017: Bioanalysis
https://www.readbyqxmd.com/read/28205574/neuropathic-pain
#14
REVIEW
Luana Colloca, Taylor Ludman, Didier Bouhassira, Ralf Baron, Anthony H Dickenson, David Yarnitsky, Roy Freeman, Andrea Truini, Nadine Attal, Nanna B Finnerup, Christopher Eccleston, Eija Kalso, David L Bennett, Robert H Dworkin, Srinivasa N Raja
Neuropathic pain is caused by a lesion or disease of the somatosensory system, including peripheral fibres (Aβ, Aδ and C fibres) and central neurons, and affects 7-10% of the general population. Multiple causes of neuropathic pain have been described and its incidence is likely to increase owing to the ageing global population, increased incidence of diabetes mellitus and improved survival from cancer after chemotherapy. Indeed, imbalances between excitatory and inhibitory somatosensory signalling, alterations in ion channels and variability in the way that pain messages are modulated in the central nervous system all have been implicated in neuropathic pain...
February 16, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28202240/fatty-acid-profile-of-the-sea-snail-gibbula-umbilicalis-as-a-biomarker-for-coastal-metal-pollution
#15
Carla O Silva, Tiago Simões, Sara C Novais, Inês Pimparel, Luana Granada, Amadeu M V M Soares, Carlos Barata, Marco F L Lemos
Metals are among the most common environmental pollutants with natural or anthropogenic origin that can be easily transferred through the food chain. Marine gastropods are known to accumulate high concentrations of these metals in their tissues. Gibbula umbilicalis ecological importance and abundant soft tissues, which enables extent biochemical assessments, makes this particular organism a potentially suitable species for marine ecotoxicological studies. Fatty acids are carbon-rich compounds that are ubiquitous in all organisms and easy to metabolize...
February 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28193098/nanoparticle-formulation-increases-syzygium-cumini-antioxidant-activity-in-candida-albicans-infected-diabetic-rats
#16
Paula E R Bitencourt, Lariane O Cargnelutti, Carolina S Stein, Raquel Lautenchleger, Luana M Ferreira, Manuela Sangoi, Laura Denardi, Raphaela M Borges, Aline Boligon, Rafael N Moresco, Letícia Cruz, Régis A Zanette, Sydney H Alves, Maria Beatriz Moretto
CONTEXT: Syzygium cumini (L.) Skeels (Myrtaceae) is a medicinal plant widely used in folk medicine for the treatment of diabetes mellitus (DM). However, studies on the use of this plant and of nanoparticle formulations against DM-related fungal infections are scarce. OBJECTIVE: To evaluate the effect of the treatments with aqueous seed extract of S. cumini (ASc) and ASc-loaded polymeric nanoparticles (NPASc) on biochemical parameters in Candida albicans-infected diabetic rats...
December 2017: Pharmaceutical Biology
https://www.readbyqxmd.com/read/28190782/onedep-unified-wwpdb-system-for-deposition-biocuration-and-validation-of-macromolecular-structures-in-the-pdb-archive
#17
Jasmine Y Young, John D Westbrook, Zukang Feng, Raul Sala, Ezra Peisach, Thomas J Oldfield, Sanchayita Sen, Aleksandras Gutmanas, David R Armstrong, John M Berrisford, Li Chen, Minyu Chen, Luigi Di Costanzo, Dimitris Dimitropoulos, Guanghua Gao, Sutapa Ghosh, Swanand Gore, Vladimir Guranovic, Pieter M S Hendrickx, Brian P Hudson, Reiko Igarashi, Yasuyo Ikegawa, Naohiro Kobayashi, Catherine L Lawson, Yuhe Liang, Steve Mading, Lora Mak, M Saqib Mir, Abhik Mukhopadhyay, Ardan Patwardhan, Irina Persikova, Luana Rinaldi, Eduardo Sanz-Garcia, Monica R Sekharan, Chenghua Shao, G Jawahar Swaminathan, Lihua Tan, Eldon L Ulrich, Glen van Ginkel, Reiko Yamashita, Huanwang Yang, Marina A Zhuravleva, Martha Quesada, Gerard J Kleywegt, Helen M Berman, John L Markley, Haruki Nakamura, Sameer Velankar, Stephen K Burley
OneDep, a unified system for deposition, biocuration, and validation of experimentally determined structures of biological macromolecules to the PDB archive, has been developed as a global collaboration by the worldwide PDB (wwPDB) partners. This new system was designed to ensure that the wwPDB could meet the evolving archiving requirements of the scientific community over the coming decades. OneDep unifies deposition, biocuration, and validation pipelines across all wwPDB, EMDB, and BMRB deposition sites with improved focus on data quality and completeness in these archives, while supporting growth in the number of depositions and increases in their average size and complexity...
February 3, 2017: Structure
https://www.readbyqxmd.com/read/28189000/breast-milk-retinol-concentration-in-mothers-of-preterm-newborns
#18
Mayara Santa Rosa Lima, Karla Danielly da Silva Ribeiro, Jeane Franco Pires, Dalila Fernandes Bezerra, Paula Emília Nunes Ribeiro Bellot, Luana Patrícia de Oliveira Weigert, Roberto Dimenstein
BACKGROUND: Preterm newborns have low vitamin A reserves at birth, which increases their risk of morbidity and mortality. In the absence of supplementation, breast milk is the only source of this nutrient for exclusively breastfed infants. AIMS: To assess retinol concentration in preterm milk and the relationship between this retinol concentration and lactation phase, degree of prematurity, and maternal serum retinol level. STUDY DESIGN: Longitudinal study...
February 7, 2017: Early Human Development
https://www.readbyqxmd.com/read/28188498/erratum-to-titanium-scaffold-osteogenesis-in-healthy-and-osteoporotic-rats-is-improved-by-the-use-of-low-level-laser-therapy-gaalas
#19
Luana Marotta Reis de Vasconcellos, Mary Anne Moreira Barbara, Emanuel da Silva Rovai, Mariana de Oliveira França, Zahra Fernandes Ebrahim, Luis Gustavo Oliveira de Vasconcellos, Camila Deco Porto, Carlos Alberto Alves Cairo
No abstract text is available yet for this article.
February 11, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28183613/pdlla-honeycomb-like-scaffolds-with-a-high-loading-of-superhydrophilic-graphene-multi-walled-carbon-nanotubes-promote-osteoblast-in-vitro-functions-and-guided-in-vivo-bone-regeneration
#20
Edmundo Silva, Luana Marotta Reis de Vasconcellos, Bruno V M Rodrigues, Danilo Martins Dos Santos, Sergio P Campana-Filho, Fernanda Roberta Marciano, Thomas J Webster, Anderson Oliveira Lobo
Herein, we developed honeycomb-like scaffolds by combining poly (d, l-lactic acid) (PDLLA) with a high amount of graphene/multi-walled carbon nanotube oxides (MWCNTO-GO, 50% w/w). From pristine multi-walled carbon nanotubes (MWCNT) powders, we produced MWCNTO-GO via oxygen plasma etching (OPE), which promoted their exfoliation and oxidation. Initially, we evaluated PDLLA and PDLLA/MWCNTO-GO scaffolds for tensile strength tests, cell adhesion and cell viability (with osteoblast-like MG-63 cells), alkaline phosphatase (ALP, a marker of osteoblast differentiation) activity and mineralized nodule formation...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
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