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https://www.readbyqxmd.com/read/28917776/apta-nanosensors-for-detection-and-quantitative-determination-of-acetamiprid-a-pesticide-residue-in-food-and-environment
#1
REVIEW
Asma Verdian
In an effort to achieve high sensitive and selective detection of pesticide residues, numerous nanomaterial-based aptasensors are currently being developed for acetamiprid analysis. Recently, aptamers as a potent alternative of antibodies are used in biosensing platforms. There is tremendous interest in utilizing of nanomaterial as basic building blocks and signaling elements in aptasensors. The nanomaterials have the unique optical and electrical properties. The combination of nanomaterial and aptamer technology has opened a new window in pesticide residues monitoring...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28916882/evaluating-a-mental-health-program-for-palestinian-refugees-in-lebanon
#2
Nasser Yassin, Asma A Taha, Zeina Ghantous, Mia Malda Atoui, Fabio Forgione
Medecins sans Frontière, an international non-governmental organization, initiated a mental health program for Palestinian refugees living in Lebanon. To evaluate the impact of the program after its completion, focus groups were conducted with three target groups: (1) patients, (2) staff, and (3) local community stakeholders. Participants voiced overall satisfaction with the program. The program provided easy access, good quality care, decreased stigma, as perceived by participants, and revealed a sense of community contentedness...
September 15, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28916493/cell-mediated-enzyme-prodrug-cancer-therapies
#3
Rachael Mooney, Asma Abdul Majid, Jennifer Batalla, Alexander J Annala, Karen S Aboody
Cell-directed gene therapy is a promising new frontier for the field of targeted cancer therapies. Here we discuss the current pre-clinical and clinical use of cell-mediated enzyme prodrug therapy (EPT) directed against solid tumors and avenues for further development. We also discuss some of the challenges encountered upon translating these therapies to clinical trials. Upon sufficient development, cell-mediated enzyme prodrug therapy has the potential to maximize the distribution of therapeutic enzymes within the tumor environment, localizing conversion of prodrug to active drug at the tumor sites thereby decreasing off-target toxicities...
September 12, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/28916460/the-effect-of-viroid-infection-of-citrus-trees-on-the-amoebicidal-activity-of-maltese-half-blood-citrus-sinensis-against-trophozoite-stage-of-acanthamoeba-castellanii-neff
#4
Ghaya Zouaghi, Asma Najar, Olfa Chiboub, Ines Sifaoui, Manef Abderrabba, Jacob Lorenzo Morales
In order to promote a local Tunisian product, this study was designed to examine, for the first time, the anti-Acanthamoeba activity (Acanthamoeba castellanii Neff) of the essential oils of Tunisian Citrus sinensis peels (Maltese half-blood) and the effect of viroid plant infection on this activity. To do so, three samples of peels' essential oils were studied: from a healthy plant (Control), a plant inoculated with Citrus exocortis viroid (CEVd) and one inoculated with hot stunt cachexia viroid (HSVd). The samples were extracted by hydrodistillation from dried peels and characterized by GC-MS...
September 12, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28915769/robotic-lymphadenectomy-of-an-internal-mammary-lymph-node-metastasis
#5
Ludovic Melly, Jean-Luc Jansens, Grégroy Kalscheuer, Asmae Belhaj, Benoît Rondelet
A 58-year-old woman was diagnosed with a left-sided lone internal mammary swollen lymph node on a routine follow-up computer tomography, 42 months after a left mastectomy in the context of a ductal carcinoma grade III. The suspected metastasis was successfully removed in toto using a 3-port-da Vinci robotic procedure and the patient was discharged home without any complication on the third postoperative day. Robotically assisted oncological lymph node removal is safe, easily performed and economically affordable...
September 15, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28913623/updated-strategies-for-the-management-pathogenesis-and-molecular-genetics-of-different-forms-of-ichthyosis-syndromes-with-prominent-hair-abnormalities
#6
REVIEW
Madiha Rasheed, Shaheen Shahzad, Afifa Zaeem, Imran Afzal, Asma Gul, Sumbal Khalid
Syndromic ichthyosis is rare inherited disorders of cornification with varied disease complications. This disorder appears in seventeen subtypes associated with severe systematic manifestations along with medical, cosmetic and social problems. Syndromic ichthyosis with prominent hair abnormalities covers five major subtypes: Netherton syndrome, trichothiodystrophy, ichthyosis hypotrichosis syndrome, ichthyosis hypotrichosis sclerosing cholangitis and ichthyosis follicularis atrichia photophobia syndrome. These syndromes mostly prevail in high consanguinity states, with distinctive clinical features...
September 14, 2017: Archives of Dermatological Research
https://www.readbyqxmd.com/read/28912474/rhus-coriaria-increases-protein-ubiquitination-proteasomal-degradation-and-triggers-non-canonical-beclin-1-independent-autophagy-and-apoptotic-cell-death-in-colon-cancer-cells
#7
Khawlah Athamneh, Hussain El Hasasna, Halima Al Samri, Samir Attoub, Kholoud Arafat, Nehla Benhalilou, Asma Al Rashedi, Yusra Al Dhaheri, Synan AbuQamar, Ali Eid, Rabah Iratni
Colorectal cancer is the fourth leading cause of cancer-related deaths worldwide. Here, we investigated the anticancer effect of Rhus coriaria extract (RCE) on HT-29 and Caco-2 human colorectal cancer cells. We found that RCE significantly inhibited the viability and colony growth of colon cancer cells. Moreover, RCE induced Beclin-1-independent autophagy and subsequent caspase-7-dependent apoptosis. Blocking of autophagy by chloroquine significantly reduced RCE-induced cell death, while blocking of apoptosis had no effect on RCE-induced cell death...
September 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28911348/asthma-the-increasing-unchecked-epidemic
#8
Asma El Sony
No abstract text is available yet for this article.
October 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28903610/a-broad-ligament-pregnancy-successfully-managed-by-laparoscopy
#9
Asma Sassi, Kaouther Dimassi, Sana Ben Slama, Amel Triki, Ahlem Lahmar
No abstract text is available yet for this article.
September 14, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28900324/a-significant-breakthrough-in-the-incidence-of-childhood-cancers-and-evaluation-of-its-risk-factors-in-southern-iran
#10
Asma Erjaee, Maryam Niknam, Ahmadreza Sadeghi, Maryam Dehghani, Zeinab Safaei, Saeed Hosseini Teshnizi, Mehran Karimi
BACKGROUND AND OBJECTIVE: This study investigates epidemiologic and practical information about the incidence and risk factors of childhood cancer in a population of Southern Iranian children. MATERIALS AND METHODS: A total number of 300 cancer patients along with 600 age- and gender-matched healthy control were interviewed by a trained physician regarding their demographic characteristics, and major family-associated risk factors, childhood malignancies. RESULTS: The average annual percentage change for cancers in the studied population is calculated as 45%...
April 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/28895062/effect-of-electrospinning-parameters-on-morphological-properties-of-pvdf-nanofibrous-scaffolds
#11
Asma Sadat Motamedi, Hamid Mirzadeh, Fereshteh Hajiesmaeilbaigi, Shadab Bagheri-Khoulenjani, MohammadAli Shokrgozar
Smart materials like piezoelectric polymers represent a new class of promising scaffold in neural tissue engineering. In the current study, the fabrication processing parameters of polyvinylidine fluoride (PVDF) nanofibrous scaffold are found as a potential scaffold with nanoscale morphology and microscale alignment. Electrospinning technique with the ability to mimic the structure and function of an extracellular matrix is a preferable method to customize the scaffold features. PVDF nanofibrous scaffolds were successfully fabricated by the electrospinning technique...
September 11, 2017: Progress in biomaterials
https://www.readbyqxmd.com/read/28894400/a-combination-of-trimethoprim-sulfamethoxazole-and-ceftazidime-showed-good-in-vitro-activity-against-stenotrophomonas-maltophilia
#12
Nabilah Ismail, Zarifah Zam, Siti Asma Hassan, Zaidah Abdul Rahman
BACKGROUND: Stenotrophomonas maltophilia has emerged as an important nosocomial pathogen, capable of causing a wide spectrum of infections. Treatment is difficult because it is resistant to many antimicrobial agents, thus reducing the treatment options. The aims of this study were to describe the antimicrobial susceptibility patterns and synergistic effect of selected antimicrobial combinations against S. maltophilia isolates. METHODS: This was a descriptive cross-sectional study undertaken in the Hospital Universiti Sains Malaysia from April 2011 to March 2012...
March 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28893900/labetalol-versus-nifedipine-as-antihypertensive-treatment-for-chronic-hypertension-in-pregnancy-a-randomized-controlled-trial
#13
Louise M Webster, Jenny E Myers, Catherine Nelson-Piercy, Kate Harding, J Kennedy Cruickshank, Ingrid Watt-Coote, Asma Khalil, Cornelia Wiesender, Paul T Seed, Lucy C Chappell
Data from randomized controlled trials to guide antihypertensive agent choice for chronic hypertension in pregnancy are limited; this study aimed to compare labetalol and nifedipine, additionally assessing the impact of ethnicity on treatment efficacy. Pregnant women with chronic hypertension (12(+0)-27(+6) weeks' gestation) were enrolled at 4 UK centers (August 2014 to October 2015). Open-label first-line antihypertensive treatment was randomly assigned: labetalol- (200-1800 mg/d) or nifedipine-modified release (20-80 mg/d)...
September 11, 2017: Hypertension
https://www.readbyqxmd.com/read/28891459/prevalence-of-clostridium-difficile-infection-and-colonization-in-a-tertiary-hospital-and-elderly-community-of-north-eastern-peninsular-malaysia
#14
N H Zainul, Z F Ma, A Besari, H Siti Asma, R A Rahman, D A Collins, N Hamid, T V Riley, Y Y Lee
Little is known about Clostridium difficile infection (CDI) in Asia. The aims of our study were to explore (i) the prevalence, risk factors and molecular epidemiology of CDI and colonization in a tertiary academic hospital in North-Eastern Peninsular Malaysia; (ii) the rate of carriage of C. difficile among the elderly in the region; (iii) the awareness level of this infection among the hospital staffs and students. For stool samples collected from hospital inpatients with diarrhea (n = 76) and healthy community members (n = 138), C...
September 11, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28889800/adenocarcinoma-of-the-lacrimal-gland-a-case-report
#15
Asmae Touil, Sarah El Abbassi, Yassine Echchikhi, Mustapha Maher, Tayeb Kebdani, Noureddine Benjaafar
BACKGROUND: Primary ductal adenocarcinomas of the lacrimal gland are very rare. This neoplasm shares some histological and immunohistochemical similarities with salivary duct carcinoma. CASE PRESENTATION: Here, we present a case of a 55-year-old Moroccan man with lacrimal gland adenocarcinoma. He underwent orbital exenteration with lymph nodes dissection and ipsilateral parotidectomy. After surgery, he was lost to follow-up and died 13 months later. CONCLUSIONS: Lacrimal gland tumors are rare but highly aggressive salivary gland tumors...
September 11, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28886289/optimization-of-saccharification-potential-of-recombinant-xylanase-from-bacillus-licheniformis
#16
Muhammad N Aftab, Asma Zafar, Irfana Iqbal, Afshan Kaleem, Khalid M Zia, Ali R Awan
Saccharification potential of xylanase enzyme cloned from Bacillus licheniformis into E. coli BL21 (DE3) was evaluated against plant biomass for the production of bioethanol. The expression of cloned gene was studied and conditions were optimized for its large scale production. The parameters effecting enzyme production were examined in a fermenter. Recombinant xylanase has the ability to breakdown birchwood xylan to release xylose as well as the potential to treat plant biomass, such as wheat straw, rice straw, and sugarcane bagass...
September 8, 2017: Bioengineered
https://www.readbyqxmd.com/read/28885820/strategies-for-editing-virulent-staphylococcal-phages-using-crispr-cas10
#17
S M Nayeemul Bari, Forrest C Walker, Katie Cater, Barbaros Aslan, Asma Hatoum-Aslan
Staphylococci are prevalent skin-dwelling bacteria that are also leading causes of antibiotic-resistant infections. Viruses that infect and lyse these organisms (virulent staphylococcal phages) can be used as alternatives to conventional antibiotics and represent promising tools to eliminate or manipulate specific species in the microbiome. However, since over half their genes have unknown functions, virulent staphylococcal phages carry inherent risk to cause unknown downstream side effects. Further, their swift and destructive reproductive cycle make them intractable by current genetic engineering techniques...
September 8, 2017: ACS Synthetic Biology
https://www.readbyqxmd.com/read/28882205/de-novo-design-of-iron-sulfur-proteins
#18
Zahra B Dizicheh, Nicholas Halloran, William Asma, Giovanna Ghirlanda
Iron-sulfur proteins are one of the most abundant and functionally pliable redox proteins found in all living organisms. Because of their crucial role in mediating electron transfer processes, minimalist model systems have been developed as a proxy to study natural Fe-S redox proteins and to dissect rules to enable tuning of their redox and electron transfer activities. This goal has been pursued through computational design, mutagenesis in the first and second coordination sphere, metal substitution, cofactor replacement, and the use of unnatural amino acids to stabilize a given cluster...
2017: Methods in Enzymology
https://www.readbyqxmd.com/read/28881777/ova12-promotes-tumor-growth-by-regulating-p53-expression-in-human-cancer-cells
#19
Renfeng Zhang, Xicai Wu, Xiangfeng Xia, Asma Khanniche, Feifei Song, Bingchang Zhang, Ying Wang, Hailiang Ge
Ovarian cancer-associated antigen 12 (OVA12) was first identified in an ovarian carcinoma complementary DNA (cDNA) expression library and has been shown to play an important role in tumor growth. Here, we found that overexpression of OVA12 accelerated tumor growth in different tumor cells, whereas OVA12 depletion was associated with the opposite effect. Moreover, knocking down OVA12 led to a significant increase in the protein levels of p53, and the overexpression of OVA12 significantly decreased endogenous p53 levels...
August 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28879478/influence-of-oxygen-availability-on-the-metabolism-and-morphology-of-yarrowia-lipolytica-insights-into-the-impact-of-glucose-levels-on-dimorphism
#20
Asma Timoumi, Carine Bideaux, Stéphane E Guillouet, Yohan Allouche, Carole Molina-Jouve, Luc Fillaudeau, Nathalie Gorret
Dynamic behavior of Yarrowia lipolytica W29 strain under conditions of fluctuating, low, and limited oxygen supply was characterized in batch and glucose-limited chemostat cultures. In batch cultures, transient oscillations between oxygen-rich and -deprived environments induced a slight citric acid accumulation (lower than 29 mg L(-1)). By contrast, no citric acid was detected in continuous fermentations for all stress conditions: full anoxia (zero pO2 value, 100% N2), limited (zero pO2 value, 75% of cell needs), and low (pO2 close to 2%) dissolved oxygen (DO) levels...
September 6, 2017: Applied Microbiology and Biotechnology
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