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https://www.readbyqxmd.com/read/28917582/preterm-pre-eclampsia-what-every-neonatologist-should-know
#1
REVIEW
Lisa Story, Lucy C Chappell
Although pre-eclampsia affects 5-10% of pregnancies globally and is responsible for substantial maternal and perinatal morbidity and mortality, currently there is no cure other than delivery of the baby. Predictive screening tests based on clinical risk factors, with or without the addition of biomarkers and imaging, have been developed, but adoption into clinical practice is limited by suboptimal test performance. Once established pre-eclampsia is diagnosed, a woman is usually managed expectantly prior to 37weeks' gestation to reduce perinatal morbidity and mortality associated with iatrogenic prematurity until maternal or fetal triggers for delivery mean that risks of pregnancy prolongation outweigh the benefits...
September 13, 2017: Early Human Development
https://www.readbyqxmd.com/read/28916875/traumatic-injuries-to-the-pregnant-patient-a-critical-literature-review
#2
REVIEW
P Petrone, P Jiménez-Morillas, A Axelrad, C P Marini
INTRODUCTION: Trauma during pregnancy is the leading non-obstetrical cause of maternal death and a significant public health burden. This study reviews the most common causes of trauma during pregnancy, morbidity, and mortality, and the impact upon perinatal outcomes associated with trauma, providing a management approach to pregnant trauma patients. MATERIALS AND METHODS: A systematic review of the current literature from January 2006 to July 2016 was performed...
September 15, 2017: European Journal of Trauma and Emergency Surgery: Official Publication of the European Trauma Society
https://www.readbyqxmd.com/read/28916366/measuring-progress-and-projecting-attainment-on-the-basis-of-past-trends-of-the-health-related-sustainable-development-goals-in-188-countries-an-analysis-from-the-global-burden-of-disease-study-2016
#3
(no author information available yet)
BACKGROUND: The UN's Sustainable Development Goals (SDGs) are grounded in the global ambition of "leaving no one behind". Understanding today's gains and gaps for the health-related SDGs is essential for decision makers as they aim to improve the health of populations. As part of the Global Burden of Diseases, Injuries, and Risk Factors Study 2016 (GBD 2016), we measured 37 of the 50 health-related SDG indicators over the period 1990-2016 for 188 countries, and then on the basis of these past trends, we projected indicators to 2030...
September 8, 2017: Lancet
https://www.readbyqxmd.com/read/28915850/-love-me-parents-impact-evaluation-of-a-national-social-and-behavioral-change-communication-campaign-on-maternal-health-outcomes-in-tanzania
#4
Michelle R Kaufman, Jennifer J Harman, Marina Smelyanskaya, Jennifer Orkis, Robert Ainslie
BACKGROUND: Despite marked improvements over the last few decades, maternal mortality in Tanzania remains among the world's highest at 454 maternal deaths per 100,000 live births. Many factors contribute to this disparity, such as a lack of attendance at antenatal care (ANC) services and low rates of delivery at a health facility with a skilled provider. The Wazazi Nipendeni (Love me, parents) social and behavioral change communication campaign was launched in Tanzania in 2012 to improve a range of maternal health outcomes, including individual birth planning, timely ANC attendance, and giving birth in a healthcare facility...
September 15, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28915802/determinants-of-pre-eclampsia-eclampsia-among-women-attending-delivery-services-in-selected-public-hospitals-of-addis-ababa-ethiopia-a-case-control-study
#5
Teklit Grum, Abiy Seifu, Mebrahtu Abay, Teklit Angesom, Lidiya Tsegay
BACKGROUND: Pre-eclampsia is a pregnancy-specific hypertensive disorder usually occurs after 20 weeks of gestation. It is one of the leading causes of maternal and perinatal morbidity and mortality worldwide. In Ethiopia, the major direct obstetric complications including pre-eclampsia/eclampsia account for 85% of the maternal deaths. Unlike deaths due to other direct causes, pre-eclampsia/ eclampsia related deaths appear to be increasing and linked to multiple factors, making prevention of the disease a continuous challenge...
September 15, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28913687/non-atherosclerotic-vascular-disease-in-women
#6
REVIEW
Lee Joseph, Esther S H Kim
Takayasu arteritis, fibromuscular dysplasia (FMD), spontaneous arterial dissection, Raynaud's phenomenon, and chilblains are vascular conditions that are associated with an increased predisposition in women and are often underdiagnosed. Takayasu arteritis has an incidence rate of 2.6 cases per million individuals per year in the USA and predominantly affects women of childbearing age. HLA-B5 genetic locus is linked with Takayasu arteritis susceptibility. Methods to determine active disease are limiting; currently utilized clinical and imaging findings and laboratory tests are of limited value for this purpose...
September 14, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/28913146/fetomaternal-outcomes-in-pregnant-women-with-hepatitis-e-infection-still-an-important-fetomaternal-killer-with-an-unresolved-mystery-of-increased-virulence-in-pregnancy
#7
Namrata Kumar, Vinita Das, Anjoo Agarwal, Amita Pandey, Smriti Agrawal
OBJECTIVE: Hepatitis is a prevalent infection in developing countries. While hepatitis B and C are deepening their roots in the developed world, hepatitis A and E are common in the developing world. The uniqueness of hepatitis is in its transformation from a relatively self-limiting disease in the non-pregnant state, to a highly virulent disease during pregnancy. MATERIALS AND METHODS: This retrospective observational study was conducted in the Department of Obstetrics and Gynecology, King George's Medical University, Lucknow, for a period of six months from June 2016 to November 2016 [probably during an endemic peak of hepatitis E virus (HEV)] to observe the clinical outcomes in HEV-infected pregnant women...
June 2017: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28913132/the-incidence-risk-factors-and-mortality-of-preterm-neonates-a-prospective-study-from-jordan-2012-2013
#8
Nadin M Abdel Razeq, Yousef S Khader, Anwar M Batieha
OBJECTIVE: To explore the incidence of preterm delivery, maternal risk factors for having a preterm neonate, and preterm neonates' mortality in Jordan. MATERIALS AND METHODS: A cross-sectional population-based design was applied. Socio-demographic, perinatal, delivery risk factors, and survival information were gathered in pre- and post-hospital discharge interviews with 21075 women who gave birth to live neonates at ≥20 weeks of gestation in 18 hospitals in Jordan...
March 2017: Turk J Obstet Gynecol
https://www.readbyqxmd.com/read/28912949/a-comprehensive-analysis-on-child-mortality-and-its-determinants-in-bangladesh-using-frailty-models
#9
Jahidur Rahman Khan, Nabil Awan
BACKGROUND: Bangladesh has experienced a significant reduction of child mortality over the past decades which helped achieve the Millennium Development Goal 4 (MDG 4) target. But the mortality among under-5 aged children is still relatively high and it needs a substantial effort to achieve the Sustainable Development Goal (SDG) target and decelerate the current rate of under-5 mortality. At this stage, it is hence important to explore the trend and determinants of under-5 mortality in order to reduce the vulnerability of child's survival...
2017: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/28911139/preeclampsia-downregulates-micrornas-in-fetal-endothelial-cells-roles-of-mir-29a-c-3p-in-endothelial-function
#10
Chi Zhou, Qing-Yun Zou, Hua Li, Rui-Fang Wang, Ai-Xia Liu, Ronald R Magness, Jing Zheng
Context: Preeclampsia is a leading cause of fetal and maternal morbidity and mortality during pregnancy. Although the etiology of preeclampsia is unknown, preeclampsia offspring have increased risks of developing cardiovascular disorders in adulthood, implicating that preeclampsia programs fetal vasculature in utero. Objective: We hypothesize that preeclampsia alters expression profiles of endothelial microRNAs (miRNAs) in fetal endothelial cells and disturbs the vascular endothelial growth factor A (VEGFA)- and fibroblast growth factor 2 (FGF2)-induced endothelial function...
September 1, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28910784/fetal-surgery-for-myelomeningocele-a-systematic-review-and-meta-analysis-of-outcomes-in-fetoscopic-versus-open-repair
#11
Sandra K Kabagambe, Guy W Jensen, Yue Julia Chen, Melissa A Vanover, Diana L Farmer
BACKGROUND/OBJECTIVES: The Management of Myelomeningocele (MMC) Study (MOMS) showed that prenatal repair of MMC resulted in improved neurological outcomes but was associated with high rates of obstetrical complications. This study compares outcomes of open and fetoscopic MMC repair. DATA SOURCES: PubMed and Embase studies reporting outcomes of fetal MMC repair published since the completion of the MOMS. RESULTS: We analyzed 11 studies and found no difference in mortality or the rate of shunt placement for hydrocephalus...
September 15, 2017: Fetal Diagnosis and Therapy
https://www.readbyqxmd.com/read/28910392/karyotype-analysis-and-sex-determination-in-australian-brush-turkeys-alectura-lathami
#12
Madison T Ortega, Dustin J Foote, Nicholas Nees, Jason C Erdmann, Charles D Bangs, Cheryl S Rosenfeld
Sexual differentiation across taxa may be due to genetic sex determination (GSD) and/or temperature sex determination (TSD). In many mammals, males are heterogametic (XY); whereas females are homogametic (XX). In most birds, the opposite is the case with females being heterogametic (ZW) and males the homogametic sex (ZZ). Many reptile species lack sex chromosomes, and instead, sexual differentiation is influenced by temperature with specific temperatures promoting males or females varying across species possessing this form of sexual differentiation, although TSD has recently been shown to override GSD in Australian central beaded dragons (Pogona vitticeps)...
2017: PloS One
https://www.readbyqxmd.com/read/28906307/lc-i-pelvic-ring-injury-not-benign-to-the-developing-fetus
#13
John C Weinlein, Rakesh P Mashru, Edward A Perez, Sara E Johnson
OBJECTIVE: To determine if certain patterns of pelvic ring injury are associated with more frequent intra-uterine fetal demise (IUFD). DESIGN: Retrospective review SETTING:: Level 1 trauma center. PATIENTS/PARTICIPANTS: Of 44 pregnant patients with pelvic and/or acetabular fractures, 40 had complete records that allowed determination of fetal viability. Chi-square tests were used for categorical variables (Fisher's exact tests when expected cell counts were fewer than five) and t-tests were used for continuous variables...
September 11, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28905692/the-emerging-challenge-of-optimal-blood-pressure-management-and-hypertensive-syndromes-in-pregnant-women-with-sickle-cell-disease-a-review
#14
Nabilah F Lari, Michael R DeBaun, Samuel A Oppong
Sickle cell disease (SCD) is the most common hemoglobinopathy, affecting a considerable proportion of black populations of African origin, Middle East and in the Indian sub-continent. Women with SCD are more likely to experience adverse pregnancy and delivery outcomes. Hypertensive diseases in pregnancy such as preeclampsia and eclampsia are more common in women with sickle cell disease. Areas covered: This review examined the influence of hypertension and SCD in pregnancy, and provides the preliminary evidence that the traditional systolic and diastolic blood pressure thresholds for hypertensive disorders such as pre-eclampsia and eclampsia may require reassessment in pregnant women with SCD...
September 14, 2017: Expert Review of Hematology
https://www.readbyqxmd.com/read/28904957/echocardiographic-techniques-of-deformation-imaging-in-the-evaluation-of-maternal-cardiovascular-system-in-patients-with-complicated-pregnancies
#15
REVIEW
Silvia Visentin, Chiara Palermo, Martina Camerin, Luciano Daliento, Denisa Muraru, Erich Cosmi, Luigi P Badano
Cardiovascular diseases (CVD) represent the leading cause of maternal mortality and morbidity. Knowledge of CVD in women is constantly evolving and data are emerging that female-specific risk factors as complications of pregnancy are conditions associated with an increased risk for the long-term development of CVD. Echocardiography is a safe and effective imaging technique indicated in symptomatic or asymptomatic pregnant women with congenital heart diseases who require close monitoring of cardiac function...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28904729/evaluation-of-the-maternal-mortality-surveillance-system-in-mutare-district-zimbabwe-2014-2015-a-cross-sectional-study
#16
Faith Mutsigiri-Murewanhema, Patron Trish Mafaune, Tsitsi Juru, Notion Tafara Gombe, Donewell Bangure, More Mungati, Mufuta Tshimanga
INTRODUCTION: In Zimbabwe the integrated disease surveillance and response guidelines include maternal mortality as a notifiable event reported through the Maternal Mortality Surveillance System (MMSS). A preliminary review of the MMSS data for Mutare district for the period January to June 2014 revealed that there were some discrepancies in cases notified and those captured on the T5 monthly return form. There were also delays in reporting of some maternal deaths. Poor reporting indicated shortcomings in the MMSS in Mutare district and we therefore sought to assess the performance of the maternal mortality surveillance system in Mutare district...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28904676/-gestational-diabetes-revealed-by-inaugural-diabetic-ketoacidosis-about-a-case
#17
Serge Irie Bi Gohi, Pete Yaich, Koffi N'guessan, Bernard Ogondon, Yapo Brouh
Ketoacidosis complicating gestational diabetes is rare and responsible for severe maternal-fetal mortality. It is an acute metabolic emergency whose management is multidisciplinary. Early diagnosis and treatment affect the vital prognosis of both the mother and the fetus. We report the case of a 27-year old pregnant woman at term, with a family history of diabetes, admitted to the emergency obstetric care with alertness problems associated with dyspnoea. The diagnosis of inaugural ketoacidosis decompensated due to severe malaria associated with gestational diabetes was retained on the basis of patient's medical history, of clinical examination and paraclinical assessment...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28904664/-pregnancy-and-delivery-in-patients-with-a-personal-history-of-cesarean-section-in-dakar-epidemiological-clinical-therapeutic-and-prognostic-aspects
#18
Cyr Espérance Koulimaya-Gombet, Abdoul Aziz Diouf, Moussa Diallo, Anna Dia, Codou Sène, Jean Charles Moreau, Alassane Diouf
The aim of our study was to determine hospitalization rate for vaginal birth after cesarean section in Pikine, to evaluate the quality of the management of pregnant women with previous cesarean section and to determine prognostic factors of the outcome of a trial of scar. We conducted a retrospective study based on medical records and operational protocols of patients who underwent vaginal birth after cesarean section over the period 1 January 2010 - 31 December 2011. We analyzed socio-demographic data, pregnancy follow-up, therapeutic modalities and prognosis...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28904542/claims-about-medical-malpractices-resulting-in-maternal-and-perinatal-mortality-referred-to-iranian-legal-medicine-organization-during-2011-2012
#19
Ziba Taghizadeh, Maryam Pourbakhtiar, Masoud Ghadipasha, Kamran Soltani, Khadijeh Azimi
BACKGROUND: Obstetricians, gynecologists, and midwives are the most common specialists of the medical sciences group against whom medical malpractices are claimed, many of which are avoidable and preventable. Therefore, the present study was conducted to investigate the causes of claims regarding medical malpractices resulting in maternal and perinatal mortality. MATERIALS AND METHODS: A descriptive cross-sectional study was conducted and 7616 claims of medical malpractices in the field of obstetrics, gynecology, and midwifery that were referred from all 31 provinces to the central commission of legal medicine were studied during 2011-2012...
July 2017: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/28904118/nutrition-interventions-in-the-lives-saved-tool-list
#20
REVIEW
Adrienne Clermont, Neff Walker
The Lives Saved Tool (LiST) was initially developed in 2003 to estimate the impact of increasing coverage of efficacious interventions on under-5 mortality. Over time, the model has been expanded to include more outcomes (neonatal mortality, maternal mortality, stillbirths) and interventions. The model has also added risk factors, such as stunting and wasting, and over time has attempted to capture a full range of nutrition and nutrition-related interventions (e.g., antenatal supplementation, breastfeeding promotion, child supplemental feeding, acute malnutrition treatment), practices (e...
September 13, 2017: Journal of Nutrition
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