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Oral dysplasi

Z T Zhou, S L Zhang, Y Wang
Grading objectively serious degree of oral mucosal premalignancy has instructive significance to its outlook and effectiveness.In order to supply experimental foundation of diagnosis epithelial dysplasis accruately,the sample of golden hamster premalignancy induced by dimethyblenzanthracence(DMBA) were made and observed microscopically.The results were recorded one by one according to 12-item criteria of WHO.The results showed that 12-item criteria could summarized wholly the histopathological varied features in the every stage of epithelial dysplasia The frequency of occurrence of 12-itemcriterias suggests that the starting site of premalignancy be at the basal layer...
March 1997: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
M B Hassanin, S H Ashrafi
The early chemically induced epithelial dysplastic changes in the hamster's cheek pouch were studied using light, scanning, and transmission electron microscopy. Epithelial dysplasia was noticed on the light microscopic level by the sixth week of the experiment and became marked by the eighth week. At the scanning electron microscopic level, surface alterations with features previously reported in early epithelial dysplasis in human and oral mucosa were seen by the second week of the experiment and progressed over time...
May 1988: Ultrastructural Pathology
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