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https://www.readbyqxmd.com/read/27905115/treatment-for-hereditary-angioedema-with-normal-c1-inh-and-specific-mutations-in-the-f12-gene-hae-fxii
#1
K Bork, K Wulff, G Witzke, J Hardt
Hereditary angioedema with normal C1 esterase inhibitor and mutations in the F12 gene (HAE-FXII) is associated with skin swellings, abdominal pain attacks, and the risk of asphyxiation due to upper airway obstruction. It occurs nearly exclusively in women. We report our experience treating HAE-FXII with discontinuation of potential trigger factors and drug therapies. The study included 72 patients with HAE-FXII. Potential triggers included estrogen-containing oral contraceptives (eOC), hormonal replacement therapy, or angiotensin-converting enzyme inhibitors...
November 6, 2016: Allergy
https://www.readbyqxmd.com/read/27891453/efficacy-of-ketamine-as-an-adjunct-to-local-anesthesia-in-the-surgical-removal-of-impacted-mandibular-third-molars-a-split-mouth-prospective-controlled-clinical-study
#2
Anand Shah, Rajshekhar Halli, Yash Merchant, Rajesh Kshirsagar, Jyotsana Khurana
INTRODUCTION: The removal of impacted teeth is one of the most common procedures performed by oral and maxillofacial surgeons. Reduction of discomfort post-operatively and efficient local anesthesia are imperative for success in surgical practice. At sub-anesthetic doses, ketamine has a noticeable analgesic action, which can be used to supplement local anesthesia with minimal side effects. AIM: To assess the efficacy of low-dose ketamine as an adjunct to local anesthesia in the management of pain, swelling and trismus after surgical removal of impacted mandibular third molars...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27844410/the-great-mimicker-metastatic-breast-carcinoma-to-the-head-and-neck-with-emphasis-on-unusual-clinical-and-pathologic-features
#3
Dikson Dibe Gondim, Rebecca Chernock, Samir El-Mofty, James S Lewis
Distant metastases are relatively common in breast cancer, but spread to the head and neck region is uncommon and can be diagnostically challenging. Pathology databases of two academic hospitals were searched for patients. The diagnoses were by morphologic comparison with the primary breast specimen (when available) or through the use of immunohistochemical stains characteristic of breast carcinoma (cytokeratin 7, mammaglobin, GCDFP15, and/or GATA3 positive-excluding new primary tumors at the respective head and neck sites)...
November 14, 2016: Head and Neck Pathology
https://www.readbyqxmd.com/read/27833246/effect-of-submucosal-or-oral-administration-of-prednisolone-on-postoperative-sequelae-following-surgical-extraction-of-impacted-mandibular-third-molar-a-randomized-controlled-study
#4
Adebayo Aremu Ibikunle, Wasiu Lanre Adeyemo, Akinola Ladipo Ladeinde
BACKGROUND: The aim of the study was to evaluate the effect of preoperatively administered submucosal and oral prednisolone on postoperative pain, facial swelling, and trismus following third molar surgery. PATIENTS AND METHODS: This was a randomized controlled trial in which subjects were randomly distributed into three groups. Group A consisted of subjects who received 40 mg oral prednisolone; Group B consisted of subjects who received 40 mg submucosal injection of prednisolone while Group C consisted of subjects who did not receive prednisolone...
September 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27799847/quality-of-life-and-symptoms-before-and-after-nasal-septoplasty-compared-with-healthy-individuals
#5
Vegard Bugten, Ann Helen Nilsen, Wenche Moe Thorstensen, Mads Henrik Strand Moxness, Marit Furre Amundsen, Ståle Nordgård
BACKGROUND: The goal of this study is to compare quality of life (Qol) and symptoms in 91 patients with a deviated nasal septum preoperatively and postoperatively with a control group of 93 healthy individuals. METHODS: All patients reported Qol on Sino-Nasal-Outcome-Test-20 (SNOT-20) and symptoms on visual analogue scale (VAS) preoperatively and 6 months after surgery and the results were compared with the controls. RESULTS: Mean SNOT-20 score improved from 1...
2016: BMC Ear, Nose, and Throat Disorders
https://www.readbyqxmd.com/read/27787270/prevention-and-management-of-injection-related-adverse-effects-in-facial-aesthetics-considerations-for-atx-101-deoxycholic-acid-injection-treatment
#6
Steven Fagien, Patricia McChesney, Meenakshi Subramanian, Derek H Jones
ATX-101 (deoxycholic acid injection; Kythera Biopharmaceuticals, Inc. [an affiliate of Allergan plc, Dublin, Ireland]) was approved in 2015 in the United States (Kybella) and Canada (Belkyra) for submental fat reduction. As expected, injection-site reactions such as pain, swelling, and bruising, which were mostly mild or moderate and transient, were common adverse events (AEs) reported in clinical trials. An exploratory Phase 3b study investigating interventions for management of injection-site AEs associated with ATX-101 treatment was recently completed...
November 2016: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27755433/effect-of-oral-administration-of-bromelain-on-postoperative-discomfort-after-third-molar-surgery
#7
Paolo Ghensi, Alessandro Cucchi, Luca Creminelli, Cristiano Tomasi, Barbara Zavan, Carlo Maiorana
INTRODUCTION: The purpose of this prospective randomized controlled clinical trial was to evaluate the effect of oral administration of bromelain on discomfort after mandibular third molar surgery. MATERIALS AND METHODS: Eighty-four consecutive patients requiring surgical removal of a single mandibular impacted third molar under local anesthesia were randomly assigned to receiving no drug (control group, Group A), postoperative 40 mg bromelain every 6 hours for 6 days (Group B), preoperative 4 mg dexamethasone sodium phosphate as a submucosal injection (Group C), and preoperative 4 mg dexamethasone sodium phosphate as a submucosal injection plus postoperative 40 mg bromelain every 6 hours for 6 days (Group D)...
October 14, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27743320/embryonal-rhabdomyosarcoma-of-the-oral-cavity
#8
Mark McInturff, Anne Adamson, Chadwick Donaldson, Brenda L Nelson
A 19 year old female presents to the emergency room with right facial enlargement. Clinical examination revealed a soft tissue mass of the right buccal mucosa. Treated initially as infection, the patient later turned to clinic with now rapidly enlarging and intermittently painful mass. Computed tomography with contrast showed a low attenuated buccal mass with mild enhancement lateral to the right caudal maxilla and superior mandible. Biopsy was performed and microscopic examination showed cells with moderate pleomorphism with numerous atypical mitotic figures and occasional elongated "strap" cells with eccentric nuclei...
October 14, 2016: Head and Neck Pathology
https://www.readbyqxmd.com/read/27721585/comparative-pre-emptive-analgesic-efficacy-study-of-novel-antiepileptic-agents-lamotrigine-and-topiramate-in-patients-undergoing-major-surgeries-at-a-tertiary-care-hospital-a-randomized-double-blind-clinical-trial
#9
Ankush Gupta, Uma A Bhosale, Priyank Shah, Radha Yegnanarayan, Shalini Sardesai
BACKGROUND: Central nervous sensitization, following surgical injury, leads to postoperative pain hypersensitivity due to lowered pain threshold in peripheral nociceptors and increased excitability of spinal neurons. Pre-emptive analgesia is intended to decrease pain perception and overall analgesic need by use of drug regimen, seizing CNS sensitization before exposure to painful stimuli. Few studies support pre-emptive analgesic efficacy of novel antiepileptic agent Gabapentin. Though Topiramate and Lamotrigine have been proven analgesic in animal models of chronic pain and clinical studies of Gabapentin-resistant neuropathic pain, literature search revealed scarce data on its pre-emptive analgesic efficacy...
September 2016: Annals of Neurosciences
https://www.readbyqxmd.com/read/27694791/cancer-and-orofacial-pain
#10
M Romero-Reyes, D Salvemini
BACKGROUND: Cancer pain is a devastating condition. Pain in the orofacial region, may be present as the single symptom of cancer or as a symptom of cancer in its later stages. This manuscript revises in a comprehensive manner the content of the conference entitled "Orofacial Pain and Cancer" (Dolor Orofacial y Cancer) given at the VI Simposio International "Advances in Oral Cancer" on the 22 July, 2016 in San Sebastioan-Donostia. MATERIAL AND METHODS: We have reviewed (pubmed-medline) from the most relevant literature including reviews, systematic reviews and clinical cases, the significant and evidence-based mechanisms and mediators of cancer-associated facial pain, the diverse types of cancers that can be present in the craniofacial region locally or from distant sites that can refer to the orofacial region, cancer therapy that may induce pain in the orofacial region as well as discussed some of the new advancements in cancer pain therapy...
November 1, 2016: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/27627971/marked-improvement-of-meige-syndrome-in-a-japanese-male-patient-with-schizophrenia-after-switching-from-risperidone-to-paliperidone-a-case-report
#11
Reiji Yoshimura, Hikaru Hori, Asuka Katsuki, Kiyokazu Atake
Meige syndrome is a relatively rare type of oral facial dystonia. The dominant symptoms involve involuntary eye blinking and chin thrusting. Some patients may experience excessive tongue protrusion, squinting, muddled speech, or uncontrollable contraction of the platysma muscle. A 44-year-old Japanese male was suffering from schizophrenia. The initial presentation of his psychosis consisted of auditory hallucinations, delusions of persecution, psychomotor excitement, loosening association, and restlessness...
September 2016: Journal of UOEH
https://www.readbyqxmd.com/read/27594910/oral-manifestations-of-lymphoma-a-systematic-review
#12
REVIEW
Taísa Domingues Bernardes Silva, Camila Belo Tavares Ferreira, Gustavo Boehmer Leite, José Roberto de Menezes Pontes, Héliton S Antunes
Lymphoma is a malignant disease with two forms: Hodgkin's lymphoma (HL) and non-Hodgkin's lymphoma (NHL). Non-Hodgkin's lymphoma is diagnosed in extranodal sites in 40% of cases, and the head and neck region is the second most affected, with an incidence of 11-33%, while HL has a very low incidence in extranodal sites (1-4%). The aim of this study was to identify the oral manifestations of lymphoma through a systematic literature review, which we conducted using the PubMed, Lilacs, Embase, and Cochrane Library databases...
2016: Ecancermedicalscience
https://www.readbyqxmd.com/read/27567997/percutaneous-ct-guided-cryoablation-of-the-salivary-glands-in-a-porcine-model
#13
Ji Y Buethe, Salim Abboud, Kristie Brock, Greg Nizialek, Rod Rezaee, Jay Wasman, Jonathan Frankel, Dean A Nakamoto
PURPOSE: To evaluate the imaging, histologic changes and safety of computed tomography (CT)-guided cryoablation of the parotid glands in a porcine model. MATERIALS AND METHODS: Unilateral CT-guided parotid gland cryoablation was performed in 5 juvenile miniature pigs. The ablated parotid glands underwent 2 cycles of 10-minute freeze and 5-minute thaw using three 17-g cryoprobes. The animals were monitored daily for complications including pain, frostbite, infection, and sialocele or fistula formation...
December 2016: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/27541635/effect-of-topical-lidocaine-in-the-oral-and-facial-regions-on-tactile-sensory-and-pain-thresholds
#14
Ichiro Okayasu, Osamu Komiyama, Takao Ayuse, Antoon De Laat
OBJECTIVE: The aim of the present study was to examine the effect of lidocaine application to the face, tongue and hand on sensory and pain thresholds of symptom-free subjects. DESIGN: Eighteen females (mean age 25.7 years, range 22-38) participated. Using Semmes-Weinstein monofilaments, the tactile detection threshold (TDT) and the filament-prick pain detection threshold (FPT) were measured on the cheek skin (CS), tongue tip (TT) and palm side of the thenar skin (TS)...
August 5, 2016: Archives of Oral Biology
https://www.readbyqxmd.com/read/27526234/comparison-of-clinical-outcome-of-facial-artery-myomucosal-flap-and-tongue-flap-for-closure-of-large-anterior-palatal-fistulas
#15
Muhammad Sohail, Muhammad Mustehsan Bashir, Farid Ahmad Khan, Noreen Ashraf
Closure of large anterior palatal fistula has high recurrence rate. The objective of this study was to compare the clinical outcome of facial artery myomucosal flap (FAMM flap) and tongue flap used for closure of large anterior palatal fistula. This study was conducted from March 2008 to March 2014. Thirty-nine patients, aged 2 to 40 years, who had anterior palatal fistula 5 to 20 mm in width with associated alveolar cleft and repaired with either a tongue flap or FAMM flap were included. Patients were excluded if they had adequate local palatal tissue for closure, mid, posterior or multiple fistulae, fistula width >20 mm...
September 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27511045/-the-historical-materials-of-stomatology-in-the-all-things-prescriptions-of-fifty-two-diseases-and-yinshu
#16
X J Li, L Zhu
All Things, Prescriptions of Fifty-two Diseases and Yinshu were three bamboo and silk medical manuscripts which form-time was no later than the late Warring States period. From the visible bamboo and silk, the ancient Chinese knew the relationships between some drugs and the volume of saliva and used compound drugs to treat dental caries. Some oral and maxillofacial diseases, such as inflammation and pain of oromaxillo-facial region, temporomandibular dislocation and the methods of treatment were descriped in these books...
August 2016: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/27487492/comparative-pre-emptive-analgesic-efficacy-study-of-novel-antiepileptic-agents-gabapentin-lamotrigine-and-topiramate-in-patients-undergoing-major-surgeries-at-a-tertiary-care-hospital-a-randomized-double-blind-clinical-trial
#17
Uma A Bhosale, Radha Yegnanarayan, Ankush Gupta, Priyank Shah, Shalini Sardesai
BACKGROUND: Surgical injury leads to postoperative pain hypersensitivity preceded by central nervous sensitization, due to lowered pain threshold in peripheral nociceptors and increased excitability of the spinal neurons. Pre-emptive analgesia is intended to decrease pain perception and overall analgesic need by use of drug regimen seizing central nervous system sensitization before exposure to painful stimuli. Earlier, few studies support pre-emptive analgesic efficacy of novel antiepileptic agent gabapentin...
August 3, 2016: Journal of Basic and Clinical Physiology and Pharmacology
https://www.readbyqxmd.com/read/27475504/classification-and-differential-diagnosis-of-oral-and-maxillofacial-pain
#18
REVIEW
Steven J Scrivani, Egilius L H Spierings
Pain in the orofacial region is a common presenting symptom. The majority of symptoms are related to dental disease and the cause can readily be established, the problem dealt with, and the pain eliminated. However, pain may persist and defy attempts at treatment. Intractable oral or facial pain can be diagnostically challenging. To make a definitive diagnosis and initiate proper treatment, a rigorous protocol for evaluation includes a thorough history and an appropriate comprehensive clinical examination and diagnostic testing, including chief complaint, history of present illness, medical history, physical examination, diagnostic studies, including imaging, and psychosocial evaluation...
August 2016: Oral and Maxillofacial Surgery Clinics of North America
https://www.readbyqxmd.com/read/27465790/antral-bony-wall-erosion-trigeminal-nerve-injury-and-enophthalmos-after-root-canal-surgery
#19
Tiago Costa, Eduardo Ferreira, Luís Antunes, Paulo Borges Dinis
INTRODUCTION: The frequently used irrigant in dental surgery, sodium hypochlorite, is occasionally the cause of minor, usually circumscribed, adverse effects. Severe, extensive complications, with lasting sequelae, however, also can occur, as in the case we report herein. CASE REPORT: A 55-year-old woman underwent an endodontic procedure on a maxillary molar, whose roots, unknown to the surgeon, were protruding into the maxillary sinus. After sodium hypochlorite root canal irrigation, the patient immediately developed intense facial pain, facial edema, and periorbital cellulitis...
January 2016: Allergy & Rhinology
https://www.readbyqxmd.com/read/27457369/evaluation-of-the-effects-of-the-low-level-laser-therapy-on-swelling-pain-and-trismus-after-removal-of-impacted-lower-third-molar
#20
Hilal Alan, Ümit Yolcu, Mahmut Koparal, Cem Özgür, Seyit Ahmet Öztürk, Sıddık Malkoç
BACKGROUND: In current study we aimed to examine the effect of a low-level laser therapy on the pain, mouth opening and swelling of patients whose impacted 3rd molar tooth was extracted in addition measurement volumetrically to the edema with 3dMD face system. METHODS: It was surveyed 15 patients who had bilateral symmetric lower 3rd molars. Surgical sides of patients were randomly separated into two groups: the study group and the control group. It was applied extra oral low-level laser therapy (LLLT, 0...
2016: Head & Face Medicine
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