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Burning mouth syndrome

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https://www.readbyqxmd.com/read/29156085/the-association-between-burning-mouth-syndrome-and-sleep-disturbance-a-case-control-multicentre-study
#1
D Adamo, A Sardella, E Varoni, C Lajolo, M Biasotto, G Ottaviani, P Vescovi, T Simonazzi, M Pentenero, M Ardore, F Spadari, G Bombeccari, L Montebugnoli, D B Gissi, G Campisi, V Panzarella, M Carbone, L Valpreda, M Giuliani, M Aria, L Lo Muzio, M D Mignogna
OBJECTIVES: To investigate the quality of sleep and the psychological profiles of a large cohort of Italian patients with burning mouth syndrome (BMS) and to clarify the relationships between these variables and pain. METHODS: In this case-control study, 200 patients with BMS versus an equal number of age and sex-matched healthy controls, recruited in 10 Universities, were enrolled. The Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Hamilton Rating Scale for Depression (HAM-D), Hamilton Rating Scale for Anxiety (HAM-A), Numeric Pain Intensity Scale (NRS) and Total Pain Rating Index (T-PRI) were administered...
November 20, 2017: Oral Diseases
https://www.readbyqxmd.com/read/29149827/therapeutic-applications-of-capsaicin-in-upper-airways
#2
Carlo Cavaliere, Simonetta Masieri, Franco Cavaliere
Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is the substance responsible of the irritation caused by the contact of chili peppers with the skin or mucous membranes. This protoalkaloid acts by stimulating the transient receptor potential cation channel subfamily V member 1 (TRPV1), which is mainly expressed by nociceptive fibers of peripheral sensory neurons, but is also present in the central nervous system, and in some non-neuronal cells. Following the initial, intense neuronal excitation, a brief refractory period occurs...
November 17, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/29117464/salivary-scintigraphy-for-sj%C3%A3-gren-s-syndrome-in-patients-with-xerostomia-a-retrospective-study
#3
Marion Nadal, Maeva Levy, Aquib Bakhsh, Aline Joly, Annabel Maruani, Loïc Vaillant, Benoît Erra, Mahtab Samimi
OBJECTIVES: The value of salivary gland scintigraphy in the diagnosis of Sjögren's syndrome remains controversial. The primary aim of this study was to estimate the diagnostic accuracy of salivary gland scintigraphy in the diagnosis of Sjögren's syndrome among 237 patients with xerostomia. METHODS: We retrospectively compared eight scintigraphy parameters between 106 Sjögren patients and 131 non-Sjögren patients. RESULTS: Seven of the eight parameters were significantly decreased in Sjögren patients; however their diagnostic accuracy was low, with AUCs ranging from 0...
November 8, 2017: Oral Diseases
https://www.readbyqxmd.com/read/29074941/orofacial-pain-an-update-on-diagnosis-and-management
#4
S Ghurye, R McMillan
The diagnosis and management of orofacial pain may be challenging due to complex histories, pathophysiology and associated psychosocial co-morbidities such as depression and anxiety. Neuropathic facial pain conditions such as burning mouth syndrome (BMS), persistent idiopathic facial pain (PIFP), atypical odontalgia (AO) and trigeminal neuralgia (TN) require early recognition by primary care clinicians and referral to secondary care. Acute pain-related temporomandibular disorder (TMD) may be managed in the primary care setting, with identification of those at risk of developing chronic TMD receiving an early referral to secondary care...
December 2017: British Dental Journal
https://www.readbyqxmd.com/read/29074062/the-role-of-psychological-factors-in-the-development-of-burning-mouth-syndrome
#5
H S Yoo, S H Jin, Y J Lee, C M Song, Y B Ji, K Tae
The psychiatric profiles of 50 patients diagnosed with burning mouth syndrome (BMS) were compared to those of 50 age- and sex-matched individuals as the control group. The Symptom Checklist-90-Revised (SCL-90-R) questionnaire was used to evaluate the role of psychological factors in the development of BMS. Somatization, obsessive-compulsive, depression, anxiety, hostility, phobic anxiety, psychoticism, global severity index (GSI), positive symptom total (PST), and positive symptom distress index (PSDI) scores were significantly higher in the patients with BMS than in the control group...
October 23, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29033766/effect-of-oral-care-gel-for-burning-mouth-syndrome-in-a-patient-with-hepatitis-c-a-case-report
#6
Yumiko Nagao, Yuji Kawahigashi, Kanae Kimura, Michio Sata
Burning mouth syndrome (BMS) is a burning sensation in the mouth with no underlying dental or medical cause. To date, there is no satisfactory treatment for BMS. Herein, we present the case of a 42-year-old female presenting with hepatitis C virus infection along with BMS. Despite two interferon therapies and a sustained virologic response, the discomfort in her oral mucosa persisted. At the age of 51, the patient complained of burning sensation and tingling pain in the tongue; a thin layer of REFRECARE-H®, an oral care gel (therapeutic dentifrice), was applied on the oral membrane after each meal for 60 days...
May 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/28972293/evaluating-burning-mouth-syndrome-as-a-comorbidity-of-atypical-odontalgia-the-impact-on-pain-experiences
#7
Trang T H Tu, Anna Miura, Yukiko Shinohara, Lou Mikuzuki, Kaoru Kawasaki, Shiori Sugawara, Takayuki Suga, Takeshi Watanabe, Motoko Watanabe, Yojiro Umezaki, Tatsuya Yoshikawa, Haruhiko Motomura, Miho Takenoshita, Akira Toyofuku
OBJECTIVE: This study aimed to: (1) investigate the differences in clinical characteristics of patients between two groups: with Atypical Odontalgia (AO) only and with Burning Mouth Syndrome (BMS) (2) assess psychiatric comorbidity factor's influence on patients' experience. METHOD: Medical records, psychiatric referral forms of patients visiting the Psychosomatic Dentistry Clinic of Tokyo Medical and Dental University between 2013-2016 were reviewed. The final sample included two groups of 355 patients: AO-only (n=272) and AO-BMS patients (n=83)...
October 3, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/28947688/-pathophysiology-and-treatment-of-orofacial-pain
#8
Masamichi Shinoda, Noboru Noma
"Pain" is one of body defense mechanisms and crucial for the life support. However, orofacial pain such as myofascial pain syndrome, burning mouth syndrome and trigeminal neuralgia plays no part in body defense mechanisms and requires therapeutic intervention. Recent studies have indicated that plastic changes in the activities of trigeminal neurons, satellite glial cells in trigeminal ganglion, secondary neurons, microglia and astrocytes in trigeminal spinal subnucleus following orofacial inflammation and trigeminal nerve injury are responsible for orofacial pain mechanisms...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28916026/a-diagnostic-and-therapeutic-approach-to-primary-burning-mouth-syndrome
#9
Siamak Moghadam-Kia, Nasim Fazel
Primary burning mouth syndrome (BMS) is an oral mucosal disorder that is characterized by a chronic and often debilitating intraoral burning sensation for which no localized or systemic cause can be found. BMS most commonly affects postmenopausal women. The pathophysiology of primary BMS is not well understood. Diagnosing BMS can prove to be challenging. BMS patients can also pose a therapeutic challenge to clinicians who are consulted to evaluate these patients. Most commonly used therapies include tricyclic antidepressants, α-lipoic acid, clonazepam, and cognitive-behavioral therapy...
September 2017: Clinics in Dermatology
https://www.readbyqxmd.com/read/28884860/pharmacological-treatment-of-oro-facial-pain-health-technology-assessment-including-a-systematic-review-with-network-meta-analysis
#10
REVIEW
B Häggman-Henrikson, P Alstergren, T Davidson, E D Högestätt, P Östlund, S Tranaeus, S Vitols, T List
This health technology assessment evaluated the efficacy of pharmacological treatment in patients with oro-facial pain. Randomised controlled trials were included if they reported pharmacological treatment in patients ≥18 years with chronic (≥3 months) oro-facial pain. Patients were divided into subgroups: TMD-muscle [temporomandibular disorders (TMD) mainly associated with myalgia]; TMD-joint (TMD mainly associated with temporomandibular joint pain); and burning mouth syndrome (BMS). The primary outcome was pain intensity reduction after pharmacological treatment...
October 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28836365/use-of-antidepressants-in-dentistry-a-systematic-review
#11
REVIEW
P A Lino, C C Martins, Gfpc Miranda, M E de Souza E Silva, Mhng de Abreu
OBJECTIVE: Previous research has suggested that antidepressants can be used in oral health care. The aim of this systematic review was to search for scientific evidence of the efficacy of the use of antidepressants in dentistry. MATERIALS AND METHODS: The clinical question was as follows (PICO question): dentistry patients (Patients); antidepressants (Intervention); no use or placebo or other drug (Comparison); and efficacy in oral health problems (Outcome). An electronic search was conducted in seven databases, as well as a manual search without restriction regarding language and date of publication...
August 24, 2017: Oral Diseases
https://www.readbyqxmd.com/read/28833164/a-case-control-evaluation-of-fungiform-papillae-density-in-burning-mouth-syndrome
#12
Jason M Naud, Laura Benca, Mark T Drangsholt, Linda LeResche, Susan E Coldwell
HYPOTHESIS: It has been hypothesized that high fungiform papillae density may be a risk factor for developing the taste and pain alterations characteristic of burning mouth syndrome. OBJECTIVE: Evaluate whether fungiform papillae density, taste sensitivity, and mechanical pain sensitivity differ between burning mouth syndrome cases and controls. STUDY DESIGN: This case-control study compared cases diagnosed with primary burning mouth syndrome with pain-free controls...
August 22, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28740270/the-significance-of-brain-transcranial-sonography-in-burning-mouth-syndrome-a-pilot-study
#13
Iris Zavoreo, Vanja Vučićević, Boras, Dijana Zadravec, Vanja Bašić, Kes, Dubravka Ciliga, Dragana Gabrić
OBJECTIVE: Burning mouth syndrome (BMS) is a chronic disorder which is affecting mostly postmenopausal women and is characterized by burning symptoms in the oral cavity on the clinically healthy oral mucosa. Also, the results of previous studies suggested a possible role of peripheral and/or central neurological disturbances in these patients. The aim of this study was to analyze patients with burning mouth syndrome using transcranial sonography. METHODS: By use of transcranial sonography of the brain parenchyma, substantia nigra, midbrain raphe and brain nucleus were evaluated in 20 patients with BMS (64...
March 2017: Acta Stomatologica Croatica
https://www.readbyqxmd.com/read/28738111/topical-clonazepam-solution-for-the-management-of-burning-mouth-syndrome-a-retrospective-study
#14
Michal Kuten-Shorrer, Nathaniel S Treister, Shannon Stock, John M Kelley, Yisi D Ji, Sook-Bin Woo, Mark A Lerman, Stefan Palmason, Stephen T Sonis, Alessandro Villa
AIMS: To evaluate and compare the effectiveness of two concentrations of topical clonazepam solution in improving symptoms of burning mouth syndrome (BMS). METHODS: A retrospective chart review was conducted of patients diagnosed with BMS and managed with topical clonazepam solution between 2008 and 2015. A 0.5-mg/mL solution was prescribed until 2012, when this was changed to a 0.1 mg/mL solution. Patients were instructed to swish with 5 mL for 5 minutes and spit two to four times daily...
July 2017: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/28691458/a-%C3%A2-burning%C3%A2-therapy-for-burning-mouth-syndrome-preliminary-results-with-the-administration-of-topical-capsaicin
#15
L Azzi, F Croveri, L Pasina, M Porrini, R Vinci, M Manfredini, L Tettamanti, A Tagliabue, J Silvestre-Rangil, F Spadari
Burning mouth syndrome is defined as an intraoral burning sensation for which no medical or dental cause can be found. Recently, researchers have demonstrated an altered trophism of the small nerve fibres and alterations in the numbers of TRPV-1 vanilloid receptors. Capsaicin is a molecule that is contained in hot peppers and is specifically detected by TRPV-1 vanilloid receptors that are distributed in the oral mucosae. We aimed at verifying if topical capsaicin could prove to be an effective treatment of Burning Mouth Syndrome...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28691457/human-%C3%AE-2-defensin-in-oral-lichen-planus-expresses-the-degree-of-inflammation
#16
L Azzi, P Moretto, R Vinci, F Croveri, A Boggio, J Silvestre-Rangil, L Tettamanti, A Tagliabue, A Passi
Syndrome (BMS). Seventeen OLP patients, with a positive histopathologic diagnosis of the disease, were recruited into this study in order to measure the relative quantity of HBD-2 in their saliva and crevicular fluid. The values were compared with those collected from a group of 9 patients affected by the Burning Mouth Syndrome (BMS) and with a control group (CTRL) of 9 patients. There was no statistically significant difference between the groups (p=0.523; p=0.897). However, patients affected by OLP showed a dycotomic distribution of values: while 10 of them showed similar values to those found out in the other two groups, 7 patients expressed high levels of HBD-2 and 3500 pg/ml was the threshold to distinguish the subgroups...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28653747/pharmacological-treatment-of-orofacial-pain-health-technology-assessment-including-a-systematic-review-with-network-meta-analysis
#17
REVIEW
B Häggman-Henrikson, P Alstergren, T Davidson, Ed Högestätt, P Östlund, S Tranaeus, S Vitols, T List
This health technology assessment evaluated the efficacy of pharmacological treatment in patients with orofacial pain. Randomised controlled trials were included if they reported pharmacological treatment in patients ≥18 years with chronic (≥3 months) orofacial pain. Patients were divided into subgroups: TMD-muscle [Temporomandibular disorders (TMD) mainly associated with myalgia]; TMD-joint (TMD mainly associated with temporomandibular joint pain); and Burning mouth syndrome (BMS). The primary outcome was pain intensity reduction after pharmacological treatment...
June 27, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28649608/distribution-and-impact-on-quality-of-life-of-the-pain-modalities-assessed-by-the-king-s-parkinson-s-disease-pain-scale
#18
Pablo Martinez-Martin, Jose Manuel Rojo-Abuin, Alexandra Rizos, Carmen Rodriguez-Blazquez, Claudia Trenkwalder, Lauren Perkins, Anna Sauerbier, Per Odin, Angelo Antonini, Kallol Ray Chaudhuri
In Parkinson's disease, pain is a prevalent and complex symptom of diverse origin. King's Parkinson's disease pain scale, assesses different pain syndromes, thus allowing exploration of its differential prevalence and influence on the health-related quality of life of patients. Post hoc study 178 patients and 83 matched controls participating in the King's Parkinson's disease pain scale validation study were used. For determining the respective distribution, King's Parkinson's disease pain scale items and domains scores = 0 meant absence and ≥1 presence of the symptom...
2017: NPJ Parkinson's Disease
https://www.readbyqxmd.com/read/28642559/little-evidence-to-support-or-refute-interventions-for-the-management-of-burning-mouth-syndrome
#19
COMMENT
Debra K Fischoff, Silvia Spivakovsky
Data sourcesCochrane Oral Health's Trials Register, Cochrane Central Register of Controlled Trials (CENTRAL), Medline Ovid, Embase Ovid, US National Institutes of Health Ongoing Trials Register (ClinicalTrials.gov) and the World Health Organization International Clinical Trials Registry Platform. Handsearch of the proceedings from the British Society for Oral Medicine (BSOM), British Society for Dental Research (BSDR) and the International Association for Dental Research (IADR).Study selectionAll included studies were randomised placebo controlled trials comparing a treatment to placebo with no language or year of publication restrictions...
June 23, 2017: Evidence-based Dentistry
https://www.readbyqxmd.com/read/28638895/chronic-orofacial-pain-burning-mouth-syndrome-and-other-neuropathic-disorders
#20
Raymond C Tait, McKenzie Ferguson, Christopher M Herndon
Chronic orofacial pain is a symptom associated with a wide range of neuropathic, neurovascular, idiopathic, and myofascial conditions that affect a significant proportion of the population. While the collective impact of the subset of the orofacial pain disorders involving neurogenic and idiopathic mechanisms is substantial, some of these are relatively uncommon. Hence, patients with these disorders can be vulnerable to misdiagnosis, sometimes for years, increasing the symptom burden and delaying effective treatment...
March 2017: Journal of Pain Management & Medicine
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