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E S Rajendran
Among all the discoveries of Hahnemann, potentisation was the most important, though controversial. The curative effect of individualised homeopathic potencies is empirical but inexplicable by the conventional principles of science. This paradox is a highly contentious topic of debate between rationalists and homeopaths. Recent discoveries relating to the nano-particulate nature of homeopathic ultra-high potencies and their potential effect on individual gene expression give new insights into this complex issue...
September 12, 2018: Homeopathy: the Journal of the Faculty of Homeopathy
Rajesh Shah
INTRODUCTION:  Analysis of data derived from homeopathic pathogenetic trials (HPTs, homeopathic drug provings) has been a challenge. Most parts of the homeopathic pharmacopeia were sourced from Hahnemann's Materia Medica Pura (1825-1833), TF Allen's Encyclopedia (1874) and Constantine Hering's Materia Medica (1879-1891), well before randomised controlled trials were in use. As a result, such studies and their outcomes harbour a large risk of inclusion of unreliable symptoms. AIMS AND OBJECTIVE: The main purpose of this article is to introduce Quantitative and Qualitative Pathogenetic Indices to improve the method of analysis of symptoms...
August 25, 2018: Homeopathy: the Journal of the Faculty of Homeopathy
Dietmar Payrhuber, Karin Thieves, Piero Sangaletti, Josef Muehlmann, Michael Frass
INTRODUCTION:  The analysis of the periodic table of elements by Jan Scholten opened the way for a new kind of classification and repertorisation of homeopathic remedies. Thereby, group analysis (resorting to series and stages) makes precise prescriptions possible. This approach appears to yield striking results, even in severe cases. Whereas Hahnemann stressed the emotional state ('Gemüthssymptome', Organon § 210) when choosing a remedy, Scholten 200 years later investigated the mental picture that represents a life conflict or even a life theme that may maintain the disease process...
June 16, 2018: Homeopathy: the Journal of the Faculty of Homeopathy
Rajesh Shah
The system of homeopathic medicine is based on the Law of Similars. It is often implied by students and practitioners of homeopathy that the fundamental principle suggests that if the substance is capable of producing certain 'symptoms', it can also remove, treat, or 'annihilate' similar symptoms if the same substance is administered in a small dose. Hahnemann clearly highlights the importance of pathogenesis or 'disease-producing power', and not just the symptoms-producing power, as a part of the 'totality of the disease'...
August 2018: Homeopathy: the Journal of the Faculty of Homeopathy
Jennifer Jacobs
BACKGROUND: Homeopathy has been used to treat epidemic diseases since the time of Hahnemann, who used Belladonna to treat scarlet fever. Since then, several approaches using homeopathy for epidemic diseases have been proposed, including individualization, combination remedies, genus epidemicus, and isopathy. METHODS: The homeopathic research literature was searched to find examples of each of these approaches and to evaluate which were effective. RESULTS: There is good experimental evidence for each of these approaches...
August 2018: Homeopathy: the Journal of the Faculty of Homeopathy
Gregory E Malat, Suzanne M Boyle, Rahul M Jindal, Stephen Guy, Gary Xiao, Meera N Harhay, Dong H Lee, Karthik M Ranganna, Mysore S Anil Kumar, Alden M Doyle
Hahnemann University Hospital has performed 120 kidney transplantations in human immunodeficiency virus (HIV)-positive individuals during the last 16 years. Our patient population represents ∼10% of the entire US population of HIV-positive kidney recipients. In our earlier years of HIV transplantation, we noted increased rejection rates, often leading to graft failure. We have established a multidisciplinary team and over the years have made substantial protocol modifications based on lessons learned. These modifications affected our approach to candidate evaluation, donor selection, perioperative immunosuppression, and posttransplantation monitoring and resulted in excellent posttransplantation outcomes, including 100% patient and graft survival at 1 year and patient and graft survival at 3 years of 100% and 96%, respectively...
April 25, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
Salvatore Chirumbolo, Geir Bjørklund
INTRODUCTION: Homeopathic remedies usually contain a significant amount of ethanol as a co-solvent with water, a pharmaceutical formulation that may raise some concern when remedies are tested in vitro or in laboratory animals, due to the assessed toxicity of ethanol on cell cultures and organisms. The amount of alcohol in a homeopathic remedy is adjusted following the different homeopathic pharmacopoeias but it is rarely below 30% v/v, which is a molar mass established to meet both Hahnemann's traditional heritage and the hypothetical role of ethanol in "imprinting" water, through the formation of nanobubbles, with the homeopathic activity of the remedy...
February 2018: Homeopathy: the Journal of the Faculty of Homeopathy
Salvatore Chirumbolo, Geir Bjørklund
Marzotto et al. showed that homeopathic preparations of Arnica montana L. acted directly on gene expression of Tamm-Horsfall protein-1 (THP-1) monocyte/macrophage cell lines activated with phorbol12-myristate13-acetate and interleukin-4 (IL-4). A. montana homeopathic dilutions are used in complementary and alternative medicine to treat inflammation disorders and post-traumatic events as well as for wound repair. The French Pharmacopoeia of these remedies uses 0.3% ethanol in each centesimal dilution. In this paper, we discuss how ethanol-containing A...
July 2017: Journal of Integrative Medicine
M L Hahnemann, A Dechene, S Kathemann, S Sirin, G Gerken, T C Lauenstein, S Kinner
AIM: To evaluate diffusion-weighted imaging (DWI) compared to standard magnetic resonance imaging (sMRI) in the assessment of inflammatory lesions of the small bowel. MATERIALS AND METHODS: Two readers retrospectively analysed MRI images of the small bowel including DWI followed by capsule endoscopy (CE) and ileocolonoscopy (ICS) in 30 consecutive patients with a suspected or established diagnosis of inflammatory bowel disease. Small bowel CE and the combination of CE + ICS were used as the standards of reference...
January 2017: Clinical Radiology
Silvia Waisse, Leoni Villano Bonamin
Facing claims for and against the scientific status of homeopathy, one is entitled to ask: is there a scientific model for homeopathy? In this study we reconstructed the model put forward by Hahnemann. The results showed that it was essentially based on the assumption of a 'vital force' exclusive to living beings. While the vital force was a basic element of 18th-century science, the existence of such a sui generis force of nature was refuted with the formulation of the law of the conservation of energy by mid-19th century...
August 2016: Homeopathy: the Journal of the Faculty of Homeopathy
Conrado Mariano Tarcitano, Silvia Waisse
Homeopathy began to spread soon after it was formulated by Samuel Hahnemann in the early 1800s, reaching the Southern Cone in the 1830s. In processes of this kind, one figure is often cited as being responsible for introducing it, often attaining quasi-mythical status. Little is known, however, about how homeopathy reached Argentina at that time. Through archival research, we discovered that medical and lay homeopaths circulated between Rio de Janeiro and Buenos Aires. Given the well-known proselytizing of the circles gravitating around lay homeopaths B...
July 2016: História, Ciências, Saúde—Manguinhos
Simone Kreher, Melanie Schlott, Thilo Schlott
As part of the research project, developments in the history of science and in the regional and ecclesiastic history of the late feudal petty state of Köthen-Anhalt have been assessed and numerous documents of the Nagel and Mühlenbein family histories examined that place the transcribed patient letters of the two Protestant clergymen within the context of the Hahnemann Archives. These findings complement and extend previous insights into Hahnemann's Köthen clientele, especially when it comes to the structure and milieu of the local clerical elite...
2016: Medizin, Gesellschaft, und Geschichte
Mads Bak, Susanne E Boonen, Christina Dahl, Johanne M D Hahnemann, Deborah J D G Mackay, Zeynep Tümer, Karen Grønskov, I Karen Temple, Per Guldberg, Niels Tommerup
BACKGROUND: Transient neonatal diabetes mellitus 1 (TNDM1) is a rare imprinting disorder characterized by intrautering growth retardation and diabetes mellitus usually presenting within the first six weeks of life and resolves by the age of 18 months. However, patients have an increased risk of developing diabetes mellitus type 2 later in life. Transient neonatal diabetes mellitus 1 is caused by overexpression of the maternally imprinted genes PLAGL1 and HYMAI on chromosome 6q24. One of the mechanisms leading to overexpression of the locus is hypomethylation of the maternal allele of PLAGL1 and HYMAI...
April 14, 2016: BMC Medical Genetics
Maria L Hahnemann, Oliver Kraff, Stefan Maderwald, Soeren Johst, Stephan Orzada, Lale Umutlu, Mark E Ladd, Harald H Quick, Thomas C Lauenstein
OBJECTIVE: To perform non-enhanced (NE) magnetic resonance imaging (MRI) of the small bowel at 7 Tesla (7T) and to compare it with 1.5 Tesla (1.5T). MATERIAL AND METHODS: Twelve healthy subjects were prospectively examined using a 1.5T and 7T MRI system. Coronal and axial true fast imaging with steady-state precession (TrueFISP) imaging and a coronal T2-weighted (T2w) half-Fourier acquisition single-shot turbo spin-echo (HASTE) sequence were acquired. Image analysis was performed by 1) visual evaluation of tissue contrast and detail detectability, 2) measurement and calculation of contrast ratios and 3) assessment of artifacts...
June 2016: Magnetic Resonance Imaging
Jens Köhler, Martin Schuler, Thomas Christoph Gauler, Stefanie Nöpel-Dünnebacke, Maike Ahrens, Andreas-Claudius Hoffmann, Stefan Kasper, Felix Nensa, Benedikt Gomez, Maria Hahnemann, Frank Breitenbuecher, Danjouma Cheufou, Filiz Özkan, Kaid Darwiche, Mathias Hoiczyk, Henning Reis, Stefan Welter, Wilfried Ernst Erich Eberhardt, Martin Eisenacher, Helmut Teschler, Georgios Stamatis, Wolff Schmiegel, Stephan Albrecht Hahn, Alexander Baraniskin
PURPOSE: Lung cancer accounts for one in five cancer deaths. Broad screening strategies for high-risk populations are unavailable, and the validation of biomarkers for early cancer detection remains a prime interest. Therefore, we investigated the value of circulating U2 small nuclear RNA fragments (RNU2-1f) as a biomarker for diagnosis, prognosis estimation and treatment monitoring in a large lung cancer cohort. METHODS: We determined RNU2-1f abundance in sera of patients with treatment-naive lung cancer (n = 211, 25...
April 2016: Journal of Cancer Research and Clinical Oncology
Florian G Mildenberger
The dispute over low and high potencies is no longer current in today's homeopathy, but from the 1830s to the 1960s it played a major role in scientific discourse. The devotees of high potencies claimed to be the only true Hahnemannians, while their antagonists tried to practise a scientific, modernized homeopathy. The former ultimately triumphed in Britain, the U.S. and Germany, but this happened on quite different routes in each of these countries. As well as Hahnemann, other scholars, such as Constantin Hering, James T...
2015: Medizin, Gesellschaft, und Geschichte
M L Hahnemann, D Wittschieber, P Becker
No abstract text is available yet for this article.
January 2016: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
(no author information available yet)
Studies have shown that patients who present to the ED with violence-related injuries are at high risk of being involved in future violent incidents. Consequently, investigators say the ED is an ideal setting to intervene with these individuals with the kind of care and support that will lead them toward a safer path. Helping Hurt People (HHP), a hospital-based trauma support program developed at Drexel University in Philadelphia, PA, has been fulfilling this function at Hahnemann University Hospital and St...
June 2015: ED Management: the Monthly Update on Emergency Department Management
Maria L Hahnemann, Oliver Kraff, Stephan Orzada, Lale Umutlu, Sonja Kinner, Mark E Ladd, Harald H Quick, Thomas C Lauenstein
OBJECTIVES: T1-weighted (T1w) contrast-enhanced magnetic resonance imaging (MRI) of the small bowel at 1.5 T magnetic field strength has become a standard technique in investigating diseases of the small bowel. High-field MRI potentially offers improved soft tissue contrast and spatial resolution, providing increased image detail. The purpose of this study was to evaluate the feasibility of contrast-enhanced small bowel MRI at 7 T and to compare results with 1.5 T. MATERIALS AND METHODS: Twelve healthy volunteers underwent small bowel MRI on a 1...
August 2015: Investigative Radiology
Mark Dzietko, Maria Hahnemann, Oliver Polley, Marco Sifringer, Ursula Felderhoff-Mueser, Christoph Bührer
Perinatal infections have a negative impact on brain development. However, the underlying mechanisms leading to neurological impairment are not completely understood and reliable models of inflammation are urgently needed. Using phorbol-myristate-acetate as an activator of inflammation, we investigated the effect on the developing rodent brain. Neonatal rats and mice deficient in IL-18 or IRAK-4 were exposed to PMA. Brains were assessed for regulation of pro- and anti-inflammatory cytokines and cell death 24 hrs, 7 and 14 days after treatment...
2015: BioMed Research International
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