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Residual yolk

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https://www.readbyqxmd.com/read/29461339/neoadjuvant-bleomycin-etoposide-and-cisplatin-bep-chemotherapy-in-the-treatment-of-extensively-advanced-yolk-sac-tumors-a-single-center-experience
#1
Gong-Yi Zhang, Rong Zhang, Ling-Ying Wu, Bin Li, Shu-Min Li
OBJECTIVE: This study aimed to investigate the role of neoadjuvant bleomycin, etoposide, and cisplatin (BEP) regimen in patients with extensively advanced yolk sac tumors (YSTs). METHODS: Between July 1982 and December 2015, a total of 58 patients with YST were initially treated at our institution, among which 18 were evaluated to be inoperable and received neoadjuvant BEP regimen. They were either too debilitated by the disease [Eastern Cooperative Oncology Group Performance Status Scale (ECOG ps) ≥2] to undergo a major surgery or were with too extensively disseminated lesions to be optimally debulked...
February 15, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29416867/onco-testicular-sperm-extraction-onco-tese-from-a-single-testis-with-metachronous-bilateral-testicular-cancer-a-case-report
#2
Itsuto Hamano, Shingo Hatakeyama, Rika Nakamura, Rie Fukuhara, Daisuke Noro, Hiroko Seino, Takahiro Yoneyama, Yasuhiro Hashimoto, Takuya Koie, Yoshihito Yokoyama, Chikara Ohyama
Background: Although oncologic testicular sperm extraction (onco-TESE) has been increasingly practiced, the evidence of onco-TESE performed in patients with testicular cancer is insufficient. Furthermore, in bilateral testicular cancer, accounting for 0.5%-1% of testicular cancers, onco-TESE is more challenging and has been insufficiently reported. Case presentation: Here we report the case of a 25-year-old man who underwent onco-TESE from his residual single testis with a nonseminomatous germ cell tumor that occurred 5 years after orchiectomy of the contralateral testis...
2018: Basic and Clinical Andrology
https://www.readbyqxmd.com/read/29370429/genetic-parameters-of-feed-efficiency-traits-and-their-relationships-with-egg-quality-traits-in-laying-period-of-ducks
#3
T Zeng, H Zhang, J Liu, L Chen, Y Tian, J Shen, L Lu
The objective of this study was to estimate genetic parameters for feed efficiency and relevant traits in 2 laying duck breeds, and to determine the relationship of residual feed intake (RFI) with feed efficiency and egg quality traits. Phenotypic records on 3,000 female laying ducks (1,500 Shaoxing ducks and 1,500 Jinyun ducks) from a random mating population were used to estimate genetic parameters for RFI, feed conversion ratio (FCR), feed intake (FI), BW, BW gain (BWG), and egg mass laid (EML) at 42 to 46 wk of age...
January 22, 2018: Poultry Science
https://www.readbyqxmd.com/read/29318787/primary-mediastinal-yolk-sac-tumor-treated-with-platinum-based-chemotherapy-and-extended-resection-report-of-seven-cases
#4
Bing Liu, Gang Lin, Jingwei Liu, Haibo Liu, Xueqian Shang, Jian Li
BACKGROUND: Primary mediastinal yolk sac tumor, which is also known as endodermal sinus tumor, is a rare but lethal neoplasm, and it is a kind of mediastinal non-seminomatous germ cell tumor. The current standard treatment in mediastinal non-seminomatous germ cell tumors is chemotherapy combined with postchemotherapy residual mass resection. We report on seven cases of primary mediastinal yolk sac tumor treated with platinum-based chemotherapy and extended resection. METHODS: We experienced seven cases of primary mediastinal yolk sac tumor between August 2014 and August 2017...
January 10, 2018: Thoracic Cancer
https://www.readbyqxmd.com/read/29187161/does-the-oviparity-viviparity-transition-alter-the-partitioning-of-yolk-in-embryonic-snakes
#5
Yan-Qing Wu, Yan-Fu Qu, Xue-Ji Wang, Jian-Fang Gao, Xiang Ji
BACKGROUND: The oviparity-viviparity transition is a major evolutionary event, likely altering the reproductive process of the organisms involved. Residual yolk, a portion of yolk remaining unutilized at hatching or birth as parental investment in care, has been investigated in many oviparous amniotes but remained largely unknown in viviparous species. Here, we used data from 20 (12 oviparous and 8 viviparous) species of snakes to see if the oviparity-viviparity transition alters the partitioning of yolk in embryonic snakes...
November 29, 2017: BMC Evolutionary Biology
https://www.readbyqxmd.com/read/29181821/combination-effects-of-organic-and-inorganic-chromium-on-production-performance-reproductive-response-immune-status-and-maternal-antibody-transmission-in-breeder-quails-under-heat-stress
#6
A Gitoee, Gh Sadeghi, A Karimi
This experiment was carried out to investigate the combination effects of organic and inorganic chromium (Cr) on egg production, egg quality, reproductive response, and immune status of breeder quails and their offspring under heat stress. A total of 140 7-week-old Japanese breeder quails (120 females and 20 males) according to a completely randomized design were used in four treatment groups (five replicate and seven birds per each) lasted for 8 weeks. Quails exposed to 35 °C for 8 h/day for induction of cyclic heat stress treatments consisted of diets supplemented with (1) 1 mg CrCl3 per kilogram of diet as control (CNT); (2) 1 mg Cr-L-Met per kilogram of diet as organic Cr (OCr); (3) 0...
November 27, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/29115161/pharmacokinetics-of-tapentadol-in-laying-hens-and-its-residues-in-eggs-after-multiple-oral-dose-administration
#7
V De Vito, H Owen, M Marzoni, T Won Kim, A Poapolathep, M Giorgi
1. The aim of the study was to evaluate the pharmacokinetics of Tapentadol (TAP), a novel opioid analgesic, in laying hens after intravenous (IV) and oral (PO) administration and to quantify the concentrations of TAP residues in eggs. 2. Twenty healthy laying hens were divided into three groups: A (n=6), B (n=6) and C (n=8). The study was conducted in 2 phases. Groups A and B received TAP by IV and PO routes at the dose of 1 and 5 mg/kg, respectively. 3. No visible adverse effects were observed after administration of the drug...
November 8, 2017: British Poultry Science
https://www.readbyqxmd.com/read/29050440/random-regression-analyses-to-model-the-longitudinal-measurements-of-yolk-proportions-in-the-laying-chicken
#8
Guo Jun, Wang Kehua, Qu Liang, Dou Taocun, Shen Manman, Ma Meng, Hu Yuping
Cubic spline function was used in a genetic evaluation to model the change of yolk proportion over the lay life. A total of 19,862 yolk proportion records of 2,324 hens was used. The evaluated submodels consisted of 3 to 6 knot models. The same knots were fitted for genetic and permanent environmental splines. The residual effects were specified to be independently and normally distributed, but with heterogeneous variance for each test week. (Co)variance components were estimated by the average information restricted maximum likelihood (AIREML) method...
September 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/29050407/layer-chicken-embryo-survival-to-hatch-when-administered-an-in-ovo-vaccination-of-strain-f-mycoplasma-gallisepticum-and-locations-of-bacteria-prevalence-in-the-newly-hatched-chick
#9
K E C Elliott, S L Branton, J D Evans, P D Gerard, E D Peebles
Mycoplasma gallisepticum (MG) is a bacterial pathogen that causes production losses in layer chickens. To combat MG, multiage layer facilities vaccinate pullets by either spray or eye-drop vaccination. The objective in this study was to evaluate the use of in ovo vaccination as a potential alternative for MG vaccination. Layer embryos at 18 d of incubation were either not-injected (control), or were hand-injected with either commercial Marek's disease vaccine diluent alone or with a high, medium, low, or very low dosage of a live attenuated strain F (FMG) vaccine suspended in the commercial diluent...
September 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/28938783/phytochemicals-reduce-aflatoxin-induced-toxicity-in-chicken-embryos
#10
Hsin-Bai Yin, Chi-Hung Chen, Michael J Darre, Ann M Donoghue, Dan J Donoghue, Kumar Venkitanarayanan
Aflatoxins (AF) are toxic metabolites produced by molds, Aspergillus flavus and Aspergillus parasiticus, which frequently contaminate poultry feed ingredients. Ingestion of AF-contaminated feed by chickens leads to deleterious effects, including decreased bird performance and reduced egg production. Moreover, AF residues in fertilized eggs result in huge economic losses by decreasing embryo viability and hatchability. This study investigated the efficacy of 2 generally recognized as safe phytochemicals, namely carvacrol (CR) and trans-cinnamaldehyde (TC), in protecting chicken embryos from AF-induced toxicity...
October 1, 2017: Poultry Science
https://www.readbyqxmd.com/read/28873610/absence-of-evidence-or-evidence-of-absence-a-transfer-and-depletion-study-of-sudan-i-in-eggs
#11
Marta Piątkowska, Piotr Jedziniak, Małgorzata Olejnik, Jan Żmudzki, Andrzej Posyniak
Sudan I is a carcinogenic industrial azo-dye, forbidden for use in food. However, it has been detected in food on several occasions, such as in paprika, used in animal husbandry to enhance egg yolk colour. Therefore, an animal experiment was designed to simulate the transfer of Sudan I to eggs after its unintentional administration to laying hens. A group of laying hens (n=18) received feed contaminated with Sudan I at the raising concentrations: 0.45mg/kg, 4.97mg/kg and 42.1mg/kg. Residues of Sudan I were detected in egg yolks (0...
January 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/28813488/role-of-post-chemotherapy-radiation-in-the-management-of-children-and-adolescents-with-primary-advanced-malignant-mediastinal-germ-cell-tumors
#12
Junting Huang, Yuting Tan, Zijun Zhen, Suying Lu, Feifei Sun, Jia Zhu, Juan Wang, Ru Liao, Xiaofei Sun
OBJECTIVE: Primary malignant mediastinal germ cell tumors (MMGCTs) are rare in children and adolescents and have a poorer prognosis than their gonadal counterparts. We report a single institutional experience of a 10-year period of primary advanced MMGCTs treated with chemotherapy, followed by radiotherapy in those who had residual mass. METHODS: Children and adolescents with primary advanced MMGCTs between 2005 and 2014 were identified from the Cancer Center, Sun Yat-Sen University...
2017: PloS One
https://www.readbyqxmd.com/read/28738003/pharmacokinetics-and-egg-residues-after-oral-administration-of-a-single-dose-of-meloxicam-in-domestic-chickens-gallus-domesticus
#13
Marcy J Souza, Joan B Bergman, Molly S White, Kristen I Gordon, Lillian E Gerhardt, Sherry K Cox
OBJECTIVE To determine the pharmacokinetics of meloxicam in domestic hens and duration and quantity of drug residues in their eggs following PO administration of a single dose (1 mg of meloxicam/kg). ANIMALS 8 healthy adult White Leghorn hens. PROCEDURES Hens were administered 1 mg of meloxicam/kg PO once. A blood sample was collected immediately before and at intervals up to 48 hours after drug administration. The hens' eggs were collected for 3 weeks after drug administration. Samples of the hens' plasma, egg whites (albumen), and egg yolks were analyzed by high-performance liquid chromatography...
August 2017: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/28711530/pitfalls-of-neuroendoscopic-biopsy-of-intraventricular-germ-cell-tumors
#14
Yasuyuki Kinoshita, Fumiyuki Yamasaki, Atsushi Tominaga, Taiichi Saito, Tetsuhiko Sakoguchi, Takeshi Takayasu, Satoshi Usui, Kazuhiko Sugiyama, Kazunori Arita, Kaoru Kurisu
OBJECTIVE: A neuroendoscopic biopsy has become common for the diagnosis of ventricular tumors. However, its utility in patients with germ cell tumors (GCTs) has not been well discussed. We examined the usefulness and pitfalls of neuroendoscopic biopsies of intraventricular GCTs at a single institution. METHODS: We retrospectively studied 21 consecutive patients diagnosed with GCTs by a neuroendoscopic biopsy of the ventricular region via the lateral ventricle. We examined the localization of tumors, histologic diagnoses using biopsies, surgical complications, and consistency of the diagnosis at the latest follow-up...
October 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28636279/effects-of-in-ovo-injection-of-chrysin-quercetin-and-ascorbic-acid-on-hatchability-somatic-attributes-hepatic-oxidative-status-and-early-post-hatch-performance-of-broiler-chicks
#15
F Khaligh, A Hassanabadi, H Nassiri-Moghaddam, A Golian, G-A Kalidari
An experiment was conducted to evaluate the effects of in ovo injection of chrysin, quercetin and ascorbic acid on hatchability, somatic attributes, hepatic antioxidant status and early post-hatch growth performance of broiler chicks. Four hundred and eighty embryonated broiler breeder eggs containing live 18-day-old embryos were divided into six groups of 80 eggs each. One group remained intact and served as a control group (i), whereas the other five groups were injected with the prepared injection solutions as follows: (ii) 0...
June 21, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28634489/a-study-of-patients-with-primary-mediastinal-germ-cell-tumors-treated-using-multimodal-therapy
#16
Yutaro Tanaka, Takehiko Okamura, Takashi Nagai, Daichi Kobayashi, Takahiro Kobayashi, Hidetoshi Akita, Yoshinobu Moritoki, Takahiro Yasui
OBJECTIVES: Primary mediastinal germ cell tumors (PMGCTs) are rare, which often makes them difficult to treat. Herein, we examined patients with PMGCTs who underwent multimodal treatment. METHODS: We examined 6 patients (median age: 25 years, range: 19-27 years) with PMGCTs who underwent multimodal treatment between April 2001 and March 2015. Three patients had seminomas, 2 patients had yolk sac tumors, and 1 patient had choriocarcinoma. The median observation period was 32...
2017: Advances in Urology
https://www.readbyqxmd.com/read/28501752/effects-of-dust-formaldehyde-and-delayed-feeding-on-early-postnatal-development-of-broiler-chickens
#17
Pieter de Gouw, Lotte J F van de Ven, Sander Lourens, Bas Kemp, Henry van den Brand
We investigated effects of perinatal exposure to dust or formaldehyde and the moment of first feed intake after hatching on broiler chicken development during the first week of life. Four environmental treatments were used from 468 until 512h of incubation: control (CONT), heat treated dust (HTD), untreated dust (UTD) or formaldehyde disinfection (FORM). After hatching, all chickens were assigned to 1 of 2 feeding treatments: early feeding (EF; feed and water available in the hatcher) or delayed feeding (DF)...
June 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28437606/transfer-study-of-silver-nanoparticles-in-poultry-production
#18
Federica Gallocchio, Giancarlo Biancotto, Veronica Cibin, Carmen Losasso, Simone Belluco, Ruud Peters, Greet van Bemmel, Claudia Cascio, Stefan Weigel, Peter Tromp, Federica Gobbo, Salvatore Catania, Antonia Ricci
Silver nanoparticles (AgNPs) are of interest due to their antimicrobial activity and are seen as potential candidates to replace antibiotics in animal husbandry. A few studies have focused on this new application, but they lack any considerations about residual accumulation of AgNPs in edible animal tissues and animal products. In this research, a 22 day in vivo study was carried out by oral administration of 20 nm spherical PVP coated AgNPs to hens. Six doses of approximately 1 mg kg(-1) of AgNPs-PVP each were administered to animals throughout the experimentation...
May 10, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28416387/differential-regulation-of-the-lipoxygenase-pathway-in-shrimp-hepatopancreases-and-ovaries-during-ovarian-development-in-the-black-tiger-shrimp-penaeus-monodon
#19
Wananit Wimuttisuk, Punsa Tobwor, Pacharawan Deenarn, Chakapong Intaraudom, Thapanee Pruksatrakul, Sutichai Nithithanasilp, Somjai Wongtripop, Suwanchai Phomklad, Panomkorn Chaitongsakul, Vanicha Vichai
Dietary polyunsaturated fatty acids (PUFAs) are critical to the success of ovarian development in marine crustaceans, especially for domesticated species such as the black tiger shrimp Penaeus monodon. These fatty acids are stored in a midgut gland called the hepatopancreas and subsequently serve as an energy source or are incorporated in yolk during ovarian development. PUFAs are known precursors of hydroxy fatty acids, including hydroxyeicosatetraenoic acid and hydroxyeicosapentaenoic acid (HEPE), which are catalyzed by lipoxygenases (LOX)...
May 27, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28412156/tyrosine-oxidation-and-nitration-in-transmembrane-peptides-is-connected-to-lipid-peroxidation
#20
Silvina Bartesaghi, Daniel Herrera, Débora M Martinez, Ariel Petruk, Verónica Demicheli, Madia Trujillo, Marcelo A Martí, Darío A Estrín, Rafael Radi
Tyrosine nitration is an oxidative post-translational modification that can occur in proteins associated to hydrophobic bio-structures such as membranes and lipoproteins. In this work, we have studied tyrosine nitration in membranes using a model system consisting of phosphatidylcholine liposomes with pre-incorporated tyrosine-containing 23 amino acid transmembrane peptides. Tyrosine residues were located at positions 4, 8 or 12 of the amino terminal, resulting in different depths in the bilayer. Tyrosine nitration was accomplished by exposure to peroxynitrite and a peroxyl radical donor or hemin in the presence of nitrite...
May 15, 2017: Archives of Biochemistry and Biophysics
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