keyword
MENU ▼
Read by QxMD icon Read
search

Blakemore

keyword
https://www.readbyqxmd.com/read/28800597/confirmation-bias-in-human-reinforcement-learning-evidence-from-counterfactual-feedback-processing
#1
Stefano Palminteri, Germain Lefebvre, Emma J Kilford, Sarah-Jayne Blakemore
Previous studies suggest that factual learning, that is, learning from obtained outcomes, is biased, such that participants preferentially take into account positive, as compared to negative, prediction errors. However, whether or not the prediction error valence also affects counterfactual learning, that is, learning from forgone outcomes, is unknown. To address this question, we analysed the performance of two groups of participants on reinforcement learning tasks using a computational model that was adapted to test if prediction error valence influences learning...
August 11, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28753485/age-related-differences-in-social-influence-on-risk-perception-depend-on-the-direction-of-influence
#2
Lisa J Knoll, Jovita T Leung, Lucy Foulkes, Sarah-Jayne Blakemore
Adolescents are particularly susceptible to social influence. Here, we investigated the effect of social influence on risk perception in 590 participants aged eight to fifty-nine-years tested in the United Kingdom. Participants rated the riskiness of everyday situations, were then informed about the rating of these situations from a (fictitious) social-influence group consisting of teenagers or adults, and then re-evaluated the situation. Our first aim was to attempt to replicate our previous finding that young adolescents are influenced more by teenagers than by adults...
July 25, 2017: Journal of Adolescence
https://www.readbyqxmd.com/read/28663304/determinants-of-post-prandial-plasma-bile-acid-kinetics-in-human-volunteers
#3
Jarlei Fiamoncini, Andrianos M Yiorkas, Kurt Gedrich, Milena Rundle, Sanne I Alsters, Guus Roeselers, Tim J van den Broek, Thomas Clavel, Ilias Lagkouvardos, Suzan Wopereis, Gary S Frost, Ben van Ommen, Alexandra I F Blakemore, Hannelore Daniel
Bile acids (BA) are signaling molecules with a wide range of biological effects, also identified amongst the most responsive plasma metabolites in the post-prandial state. We here describe this response to different dietary challenges and report on key determinants linked to its inter-individual variability. Healthy men and women (N=72, 62 ± 8 years) were enrolled into a 12-week weight loss intervention. All subjects underwent an oral glucose tolerance test (OGTT) and a mixed meal tolerance test (MMTT) before and after the intervention...
June 29, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/28651808/addendum-to-weiner-m-l-2016-parameters-and-pitfalls-to-consider-in-the-conduct-of-food-additive-research-carrageenan-as-a-case-study-food-chemical-toxicology-87-31-44
#4
Myra L Weiner, James M McKim, William R Blakemore
This paper is an addendum to a 2016 paper outlining pitfalls and parameters to consider in the conduct of food additive research with carrageenan (Fd. Chem. Tox. 87, 31-44 (2016)). The literature on the food additive, "carrageenan," contains many publications which either erroneously misuse the name, carrageenan, for a sample which is not carrageenan, but "degraded carrageenan" or "poligeenan" and also conduct studies without understanding the physical/chemical properties of carrageenan. Degraded carrageenan and poligeenan are not food additives and have a completely different physical/chemical and toxicological properties from carrageenan...
September 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/28629759/development-holds-the-key-to-understanding-the-interplay-of-nature-versus-nurture-in-shaping-the-individual
#5
EDITORIAL
Nikolaus Steinbeis, Eveline Crone, Sarah-Jayne Blakemore, Kathrin Cohen Kadosh
No abstract text is available yet for this article.
June 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28614248/endoscopic-variceal-ligation-induced-ulcer-bleeding-what-are-the-risk-factors-and-treatment-strategies
#6
Eunae Cho, Chung Hwan Jun, Sung Bum Cho, Chang Hwan Park, Hyun Soo Kim, Sung Kyu Choi, Jong Sun Rew
This study was aimed to determine the risk factors of endoscopic variceal ligation-(EVL) induced ulcer bleeding.The prevalence of EVL-induced ulcer bleeding is reported to be 3.6%. However, there are only limited reports of this serious complication, and the risk factors and the treatment methods are not well established.A total of 430 patients who had undergone EVL in Chonnam National University Hospital from January 2014 to October 2016 were studied. EVL was performed for prophylaxis or acute hemorrhage. The patients were classified into 2 groups: a bleeding group (n = 33) and a non-bleeding group (n = 397)...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28594524/adolescent-idiopathic-scoliosis-update-on-bracing-surgical-techniques-and-patient-safety
#7
Venu M Nemani, Laurel C Blakemore, Lori A Karol, Daniel W Green, Roger F Widmann
The primary goal in the management of adolescent idiopathic scoliosis is to prevent the progression of spinal deformity either with the use of a brace or with surgery. The goals of surgery, if indicated, are to correct the spinal deformity safely and to preserve overall spinal balance and as many motion segments as possible, which maximizes the long-term health of a patient's spine. Recently, tremendous advances have been made in the surgical techniques that are used to correct adolescent idiopathic scoliosis, and improved tools have allowed surgeons to perform spinal deformity surgery as safely and with as few complications as possible...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28594523/congenital-scoliosis-a-case-based-approach
#8
Frances A Farley, Laurel C Blakemore
Congenital scoliosis is lateral curvature of the spine caused by vertebral anomalies. Congenital scoliosis is associated with congenital anomalies of other organ systems. Traditionally, treatment options for patients with congenital scoliosis focused on posterior spinal fusion. Current surgical treatment options for young children include growing rods, vertical expandable prosthetic titanium ribs, and, most recently, magnetic rods. Hemivertebrae resection is an important early treatment option for patients who have a hemivertebra...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28562207/social-and-nonsocial-relational-reasoning-in-adolescence-and-adulthood
#9
Lucía Magis-Weinberg, Sarah-Jayne Blakemore, Iroise Dumontheil
Reasoning during social interactions requires the individual manipulation of mental representations of one's own traits and those of other people as well as their joint consideration (relational integration). Research using nonsocial paradigms has linked relational integration to activity in the rostrolateral pFC. Here, we investigated whether social reasoning is supported by the same general system or whether it additionally relies on regions of the social brain network, such as the medial pFC. We further assessed the development of social reasoning...
May 31, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/28497006/under-pressure-intraluminal-filling-pressures-of-postpartum-hemorrhage-tamponade-balloons
#10
Kathleen M Antony, Diana A Racusin, Michael A Belfort, Gary A Dildy
Objective Uterine tamponade by fluid-filled balloons is now an accepted method of controlling postpartum hemorrhage. Available tamponade balloons vary in design and material, which affects the filling attributes and volume at which they rupture. We aimed to characterize the filling capacity and pressure-volume relationship of various tamponade balloons. Study Design Balloons were filled with water ex vivo. Intraluminal pressure was measured incrementally (every 10 mL for the Foley balloons and every 50 mL for all other balloons)...
April 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/28482742/neurodevelopmental-outcomes-in-22-children-with-microcephaly-of-different-etiologies
#11
Eliza Gordon-Lipkin, Maura Blakemore Gentner, Rebecca German, Mary L Leppert
We examined longitudinal neurodevelopmental outcomes in a series of infants with microcephaly. Retrospective review identified neonatal intensive care unit follow-up clinic patients with a diagnostic code of microcephaly, verified by head circumference less than the fifth precentile (WHO growth curves). Data were collected regarding clinical history and developmental assessments by Capute Scales and gross motor age equivalent. Developmental Quotient (DQ) was age adjusted up until 2 years for preterm infants...
January 1, 2017: Journal of Child Neurology
https://www.readbyqxmd.com/read/28470203/soil-restore-earthworms-to-rebuild-topsoil
#12
COMMENT
Robert Blakemore, Axel Hochkirch
No abstract text is available yet for this article.
May 3, 2017: Nature
https://www.readbyqxmd.com/read/28460805/outcomes-in-variceal-hemorrhage-following-the-use-of-a-balloon-tamponade-device
#13
Jonathan Nadler, Nikola Stankovic, Amy Uber, Mathias J Holmberg, Leon D Sanchez, Richard E Wolfe, Maureen Chase, Michael W Donnino, Michael N Cocchi
BACKGROUND: Variceal hemorrhage is associated with high morbidity and mortality. A balloon tamponade device (BTD), such as the Sengstaken-Blakemore or Minnesota tube, may be used in cases of variceal hemorrhage. While these devices may be effective at controlling acute bleeding, the effect on patient outcomes remains less clear. We sought to describe the number of patients with variceal hemorrhage and a BTD who survive to discharge, survive to one-year, and develop complications related to a BTD...
April 20, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28451148/site-selective-suzuki-miyaura-coupling-of-heteroaryl-halides-understanding-the-trends-for-pharmaceutically-important-classes
#14
Joshua Almond-Thynne, David C Blakemore, David C Pryde, Alan C Spivey
Suzuki-Miyaura cross-coupling reactions of heteroaryl polyhalides with aryl boronates are surveyed. Drawing on data from literature sources as well as bespoke searches of Pfizer's global chemistry RKB and CAS Scifinder® databases, the factors that determine the site-selectivity of these reactions are discussed with a view to rationalising the trends found.
January 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28428443/mechanisms-of-pinometostat-epz-5676-treatment-emergent-resistance-in-mll-rearranged-leukemia
#15
Carly T Campbell, Jessica N Haladyna, David A Drubin, Ty M Thomson, Michael J Maria, Taylor Yamauchi, Nigel J Waters, Edward J Olhava, Roy M Pollock, Jesse J Smith, Robert A Copeland, Stephen J Blakemore, Kathrin M Bernt, Scott R Daigle
DOT1L is a protein methyltransferase involved in the development and maintenance of MLL-rearranged (MLL-r) leukemia through its ectopic methylation of histones associated with well characterized leukemic genes.  Pinometostat (EPZ-5676), a selective inhibitor of DOT1L, is in clinical development in relapsed/refractory acute leukemia patients harboring rearrangements of the MLL gene. The observation of responses and subsequent relapses in the adult trial treating MLL-r patients motivated preclinical investigations into potential mechanisms of pinometostat treatment emergent resistance (TER) in cell lines confirmed to have MLL-r...
April 20, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/28426091/distinguishing-between-homogeneous-and-heterogeneous-hydrogen-evolution-catalysis-with-molecular-cobalt-complexes
#16
David J Sconyers, James D Blakemore
Molecular proton-reduction catalysts can decompose under the acidic conditions required for hydrogen evolution, resulting in formation of secondary metal-containing materials. Using an electrochemical quartz crystal microbalance (EQCM), we report a new method for probing electrodeposition of catalytically active heterogeneous material from molecular precursors. The data collected suggest that EQCM can provide a direct measure of the homogeneity of molecular proton-reduction catalysts over short timescales.
June 29, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28420965/dopamine-a-modulator-of-circadian-rhythms-in-the-central-nervous-system
#17
REVIEW
Kirill S Korshunov, Laura J Blakemore, Paul Q Trombley
Circadian rhythms are daily rhythms that regulate many biological processes - from gene transcription to behavior - and a disruption of these rhythms can lead to a myriad of health risks. Circadian rhythms are entrained by light, and their 24-h oscillation is maintained by a core molecular feedback loop composed of canonical circadian ("clock") genes and proteins. Different modulators help to maintain the proper rhythmicity of these genes and proteins, and one emerging modulator is dopamine. Dopamine has been shown to have circadian-like activities in the retina, olfactory bulb, striatum, midbrain, and hypothalamus, where it regulates, and is regulated by, clock genes in some of these areas...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28399963/diagnostic-accuracy-of-the-xpert-%C3%A2-mtb-rif-cycle-threshold-level-to-predict-smear-positivity-a-meta-analysis
#18
B Lange, P Khan, G Kalmambetova, H A Al-Darraji, D Alland, U Antonenka, T Brown, M E Balcells, R Blakemore, C M Denkinger, K Dheda, H Hoffmann, A Kadyrov, N Lemaitre, M B Miller, V Nikolayevskyy, E N Ntinginya, N Ozkutuk, J J Palacios, E B Popowitch, J M Porcel, J Teo, G Theron, K Kranzer
SETTING: Xpert® MTB/RIF is the most widely used molecular assay for rapid diagnosis of tuberculosis (TB). The number of polymerase chain reaction cycles after which detectable product is generated (cycle threshold value, CT) correlates with the bacillary burden.OBJECTIVE To investigate the association between Xpert CT values and smear status through a systematic review and individual-level data meta-analysis. DESIGN: Studies on the association between CT values and smear status were included in a descriptive systematic review...
May 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28391628/acceptance-of-peer-navigators-to-reduce-barriers-to-cervical-cancer-screening-and-treatment-among-women-with-hiv-infection-in-tanzania
#19
Alaya Koneru, Pauline E Jolly, Shaundra Blakemore, Renicha McCree, Nedra F Lisovicz, Eric A Aris, Thereza Mtesigwa, Safina Yuma, Julius D Mwaiselage
OBJECTIVE: To identify barriers to cervical cancer screening and treatment, and determine acceptance toward peer navigators (PNs) to reduce barriers. METHODS: A cross-sectional study was conducted among women with HIV infection aged 19 years or older attending HIV clinics in Dar es Salaam, Tanzania, between May and August 2012. Data for sociodemographic characteristics, barriers, knowledge and attitude toward cervical cancer screening and treatment, and PNs were collected by questionnaire...
July 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28338837/associations-of-leukocyte-telomere-length-with-aerobic-and-muscular-fitness-in-young-adults
#20
Dylan M Williams, Jessica L Buxton, Marko T Kantomaa, Tuija H Tammelin, Alexandra I F Blakemore, Marjo-Riitta Järvelin
Decline in both telomere length and physical fitness over the life course may contribute to increased risk of several chronic diseases. The relationship between telomere length and aerobic and muscular fitness is not well characterized. We examined whether there are cross-sectional associations of mean relative leukocyte telomere length (LTL) with objective measures of aerobic fitness, muscle strength, and muscle endurance, using data on 31-year-old participants of the Northern Finland Birth Cohort 1966 (n = 4,952-5,205, varying by exposure-outcome analysis)...
April 1, 2017: American Journal of Epidemiology
keyword
keyword
27384
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"