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Obstructive sleep apnea hypopnea syndrome

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https://www.readbyqxmd.com/read/29330970/gamma-glutamyl-transferase-activity-as-a-predictive-marker-for-severity-of-obstructive-sleep-apnea-syndrome-and-concomitant-hypertension
#1
Bozkus Fulsen
BACKGROUND: Chronic intermittent hypoxia, inflammation and oxidative stress are involved in resultant obstructive sleep apnea syndrome (OSAS), which may affect numerous regulatory mechanisms that play a role in the regulation of blood pressure. Gamma glutamyl transferase (GGT) is a novel marker in the prediction of cardiovascular risk. OBJECTIVE: The objective of this study was to investigate the correlation of serum levels of GGT with hypertension and the degree of the upper airway obstruction in subjects with OSAS...
January 13, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29325335/-association-between-serum-adipocyte-fatty-acid-binding-protein-level-and-insulin-resistance-in-patients-with-osas
#2
Y B Wang, X F Li, R Chen, J H Shen, Y H Zhang
Objective: To investigate the association between serum adipocyte fatty acid binding protein (A-FABP) level and insulin resistance in patients with obstructive sleep apnea syndromes (OSAS). Methods: Eighty patients with snoring were monitored by overnight polysomnography (PSG) from September 2015 to July 2017, and there were 59 males and 21 females, aged from 22 to 77 years old (mean age 47±14 years old). Based on the apnea-hypopnea index (AHI), these patients were divided into three groups: primary snoring group (AHI<5/h, n=19), mild-moderate OSAS groups (5/h≤AHI≤30/h, n=23) and severe OSAS groups (AHI>30/h, n=38)...
December 26, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29325332/-gender-differences-of-rem-related-obstructive-sleep-apnea-hypopnea-syndrome
#3
M Xie, R Ren, J M He, X F Xue, T M Li, L Tan, F Lei, X D Tang, L H Yang
Objective: To explore the gender differences of rapid-eye-movement (REM) related obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods: Consecutive patients with primary complaint of snoring from Sleep Medicine Center of West China Hospital between January 2016 and November 2016 were included in the study. All participants underwent one night polysomnography (PSG) and Epworth sleep scale (ESS) was estimated. The patients diagnosed with OSAHS were classified as REM related OSAHS (REM-OSAHS group) and non-rapid-eye-movement (NREM) related OSAHS (NREM-OSAHS group) based on the PSG parameters...
December 26, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29308516/-evaluation-of-upper-airway-dimension-among-adolescent-patients-with-different-sagittal-skeletal-patterns-by-cone-beam-ct
#4
Xiao-Bei Hu, Kun Zhang, Da-Wei Wang, Lang Lei
PURPOSE: To analyze whether upper airway dimensions were influenced by different sagittal skeletal pattern among adolescent patients. METHODS: Seventy-five adolescent patients were divided into 3 groups based on their ANB angles.The three groups were matched for age and sex. All subjects had a normodivergent skeletal pattern.Airway lengths, cross-sectional measurements and volumes were measured by using cone-beam computed tomography (CBCT) volume scans, and two-dimensional lateral cephalograms were created and analyzed...
October 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/29302924/serum-romo1-is-significantly-associated-with-disease-severity-in-patients-with-obstructive-sleep-apnea-syndrome
#5
Liang Ye, Yingying Qian, Qian Li, Surong Fang, Zhenhua Yang, Yan Tan, Wei Gu
PURPOSE: We aim to evaluate reactive oxygen species modulator 1 (Romo1) levels in obstructive sleep apnea syndrome (OSAS) and analyze its possible relationships to OSAS severity, reactive oxygen species (ROS), and C-reactive protein (CRP). Additionally, we also investigated the effects of nasal continuous positive airway pressure (nCPAP) on serum Romo1. METHODS: One hundred and five patients diagnosed with OSAS were classified into the OSAS group, and 41 subjects without OSAS were recruited for the control group...
January 4, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29298526/comparison-of-radiofrequency-and-transoral-robotic-surgery-in-obstructive-sleep-apnea-syndrome-treatment
#6
Engin Aynacı, Murat Karaman, Burak Kerşin, Mahmut Ozan Fındık
INTRODUCTION: Radiofrequency tissue ablation (RFTA) and transoral robotic surgery (TORS) are the methods used in OSAS surgery. We also aimed to compare the advantages and disadvantages of RF and TORS as treatment methods applied in OSAS patients in terms of many parameters, especially apnea hypopnea index (AHI). MATERIALS AND METHODS: Patients were classified by performing a detailed examination and evaluation before surgery. 20 patients treated with anterior palatoplasty and uvulectomy -/+ tonsillectomy + RFTA (17 males, 3 females) and 20 patients treated with anterior palatoplasty and uvulectomy -/+  tonsillectomy + TORS (16 males, 4 females) were included in the study...
January 3, 2018: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/29298404/predictors-of-obstructive-sleep-apnea-in-consecutive-patients-with-metabolic-syndrome
#7
Rodrigo P Pedrosa, Cristiane Maki-Nunes, Thiago Midlej-Brito, Heno F Lopes, Lunara S Freitas, Ivani C Trombetta, Edgar Toschi-Dias, Maria Janieire N N Alves, Raffael F Fraga, Maria U Rondon, Carlos E Negrão, Luiz A Bortolotto, Geraldo Lorenzi-Filho, Luciano F Drager
BACKGROUND: Recent evidence suggests that obstructive sleep apnea (OSA) is common in patients with metabolic syndrome (MetS) and may contribute to metabolic deregulation, inflammation, and atherosclerosis in these patients. In clinical practice, however, OSA is frequently underdiagnosed. We sought to investigate the clinical predictors of OSA in patients with MetS. METHODS: We studied consecutive patients newly diagnosed with MetS (Adult Treatment Panel-III). All participants underwent clinical evaluation, standard polysomnography, and laboratory measurements...
January 3, 2018: Metabolic Syndrome and related Disorders
https://www.readbyqxmd.com/read/29285176/efficacy-of-continuous-positive-airway-pressure-treatment-in-treating-obstructive-sleep-apnea-hypopnea-syndrome-associated-with-carotid-arteriosclerosis
#8
Yong-Qian Jiang, Jin-Shan Xue, Juan Xu, Zhi-Xiang Zhou, You-Lin Ji
Sleep apnea negatively impacts patients' ability to oxygenate the bloodstream during sleep and has far-reaching, deleterious effects. The present study sought to assess the correlation between obstructive sleep apnea hypopnea syndrome (OSAHS), carotid atherosclerosis, and blood pressure variability (BPV), and to evaluate the therapeutic effects of continuous positive airway pressure (CPAP). Patients with OSAHS were classified as mild, moderate, or severe according to their condition and compared with healthy control participants...
December 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29277122/effects-of-minimally-invasive-surgery-for-patients-with-osa-on-quality-of-life
#9
Hsin-Ching Lin, Chee-Yee Lee, Michael Friedman, Pa-Chun Wang, Anna M Salapatas, Meng-Chih Lin, Yung-Che Chen
OBJECTIVE: To retrospectively study the effects of minimally invasive single-stage multilevel surgery (MISS MLS) for treating patients with obstructive sleep apnea/hypopnea syndrome (OSA) on quality of life (QOL). METHODS: All OSA patients with multilevel obstruction who failed or refused continuous positive airway pressure (CPAP) treatment and then underwent Pillar implants and temperature-controlled radiofrequency of the base of tongue (RFBOT) were enrolled. The subjective symptoms and QOL (SF-36 Taiwan Standard Version 1...
December 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/29231011/-research-progress-of-the-relationship-between-sunds-and-osahs
#10
REVIEW
Y D Wu, L Y Zhang, J D Cheng
Sudden unexplained nocturnal death syndrome (SUNDS) is always a difficulty in forensic medicine researches. Although the development of molecular genetics promotes the etiologic study of SUNDS, the pathogenesis of most such cases is still unclear. Sleep apnea syndrome (SAS) is one of the common forms of sleep disorders, and obstructive sleep apnea hypopnea syndrome (OSAHS) is the most common. In recent years, some domestic and international researches show that OSAHS is related to the development of cardiovascular disease, which may cause cardiac arrhythmia, even sudden death...
February 2017: Fa Yi Xue za Zhi
https://www.readbyqxmd.com/read/29204587/transoral-robotic-surgery-vs-endoscopic-partial-midline-glossectomy-for-obstructive-sleep-apnea
#11
David Folk, Mark D'Agostino
Objective: To compare sleep-related outcomes in obstructive sleep apnea hypopnea syndrome (OSAHS) patients following base of tongue resection via robotic surgery and endoscopic midline glossectomy. Methods: This was a retrospective study. A total of 114 robotic and 37 endoscopic midline glossectomy surgeries were performed between July 2010 and April 2015 as part of single or multilevel surgery. Patients were excluded for indications other than sleep apnea or if complete sleep studies were not obtained...
June 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204586/transoral-robotic-surgery-for-obstructive-sleep-apnea-syndrome-principles-and-technique
#12
Claudio Vicini, Filippo Montevecchi, Riccardo Gobbi, Andrea De Vito, Giuseppe Meccariello
Objective: The present study is a review of transoral robotic surgery (TORS) for the treatment of obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods: The review presents the experience of the robotic center that developed the technique with regards to patient selection, surgical method, and post-operative care. In addition, the review provides results of a systematic review and meta-analysis of the complications and clinical outcomes of TORS when applied in the management of OSAHS...
June 2017: World Journal of Otorhinolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/29204444/the-finite-element-simulation-of-the-upper-airway-of-patients-with-moderate-and-severe-obstructive-sleep-apnea-hypopnea-syndrome
#13
Huiping Luo, Austin Scholp, Jack J Jiang
Objectives: To investigate the snoring modes of patients with Obstructive Sleep Apnea Hypopnea Syndrome and to discover the main sources of snoring in soft tissue vibrations. Methods: A three-dimensional finite element model was developed with SolidEdge to simulate the human upper airway. The inherent modal simulation was conducted to obtain the frequencies and the corresponding shapes of the soft tissue vibrations. The respiration process was simulated with the fluid-solid interaction method through ANSYS...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29202829/prevalence-and-risk-factors-of-moderate-to-severe-obstructive-sleep-apnea-syndrome-in-major-depression-a-observational-and-retrospective-study-on-703-subjects
#14
Matthieu Hein, Jean-Pol Lanquart, Gwenolé Loas, Philippe Hubain, Paul Linkowski
BACKGROUND: Several studies have investigated the prevalence and risk factors of depression in subjects with obstructive sleep apnea syndrome. However, few studies have investigated the prevalence and risk factors for obstructive sleep apnea syndrome in major depression. The aim of this study was to examine the prevalence and risk factors of moderate to severe obstructive sleep apnea syndrome in a large sample of individuals with major depression. METHODS: Data from 703 individuals with major depression recruited from the research database of the sleep laboratory of the Erasme Hospital were analysed...
December 4, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29196149/continuous-positive-airway-pressure-treatment-with-nasal-pillows-in-obstructive-sleep-apnea-long-term-effectiveness-and-adherence
#15
Andrea Lanza, Sara Mariani, Maurizio Sommariva, Chiara Campana, Annalisa Rubino, Michele Nichelatti, Paola Proserpio, Lino Nobili
BACKGROUNDS: Mask-related side effects can negatively influence adherence to continuous positive airway pressure (CPAP). Nasal pillows (P) can be an alternative to the standard nasal masks (N), although there are no data about their long-term efficacy. This study aimed to assess long-term effectiveness and adherence to CPAP therapy delivered with nasal pillows in obstructive sleep apnea syndrome (OSAS) patients. METHODS: A retrospective observational design involving a series of consecutive CPAP-naïve patients affected by OSAS...
October 12, 2017: Sleep Medicine
https://www.readbyqxmd.com/read/29190986/the-relationship-between-obstructive-sleep-apnea-and-obesity-hypoventilation-syndrome-a-systematic-review-and-meta-analysis
#16
Chaoling Liu, Mao-Sheng Chen, Hui Yu
Obstructive Sleep Apnea and Obesity Hypoventilation Syndrome are two similar diseases. Obstructive Sleep Apnea has been receiving more and more attention while the diagnostic rate of Obesity Hypoventilation Syndrome is not high. Few studies directly evaluated the relationship between them. We systematically analyzed the relevance of the two diseases. MEDLINE®, EMBASE® and the Cochrane Library were carried out to find studies until May 2017. Pooled mean difference and 95% confidence interval were calculated to evaluate the value of clinical and physiologic variables in the prediction of Obesity Hypoventilation Syndrome...
November 3, 2017: Oncotarget
https://www.readbyqxmd.com/read/29190244/evaluation-of-obstructive-sleep-apnea-syndrome-as-a-risk-factor-for-diabetic-macular-edema-in-patients-with-type-ii-diabetes
#17
Anne-Laure Vié, Laurent Kodjikian, Emilie Agard, Nicolas Voirin, Hussam El Chehab, Philippe Denis, Olivier Coste, Corinne Dot
PURPOSE: To evaluate the association between obstructive sleep apnea and diabetic macular edema (DME) in patients with Type II diabetes, using the apnea-hypopnea index and other nocturnal hypoxemia parameters. METHODS: This cross-sectional, case-control study included 99 patients with Type II diabetes: the first group included patients with DME (DME+ group) and the second patients without DME (DME- group). Polysomnography was performed in all patients. The two groups were compared, and the risk factors were studied using logistic regression...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29189544/is-obstructive-sleep-apnea-associated-with-progressive-glaucomatous-optic-neuropathy
#18
Swarup S Swaminathan, Amitabha S Bhakta, Wei Shi, William J Feuer, Alexandre R Abreu, Alejandro D Chediak, David S Greenfield
PURPOSE: To evaluate the relationship between obstructive sleep apnea syndrome (OSAS) and glaucoma progression, and to examine the correlation between OSAS severity and rate of visual field (VF) loss. METHODS: Patients with concurrent diagnoses of open-angle glaucoma and OSAS between 2010-2016 were identified. Enrollment criteria consisted of glaucomatous optic neuropathy and VF loss, ≥5 reliable VFs, ≥2 years of follow-up, and polysomnography (PSG) within 12 months of final VF...
November 17, 2017: Journal of Glaucoma
https://www.readbyqxmd.com/read/29176802/assessment-of-automated-analysis-of-portable-oximetry-as-a-screening-test-for-moderate-to-severe-sleep-apnea-in-patients-with-chronic-obstructive-pulmonary-disease
#19
Ana M Andrés-Blanco, Daniel Álvarez, Andrea Crespo, C Ainhoa Arroyo, Ana Cerezo-Hernández, Gonzalo C Gutiérrez-Tobal, Roberto Hornero, Félix Del Campo
BACKGROUND: The coexistence of obstructive sleep apnea syndrome (OSAS) and chronic obstructive pulmonary disease (COPD) leads to increased morbidity and mortality. The development of home-based screening tests is essential to expedite diagnosis. Nevertheless, there is still very limited evidence on the effectiveness of portable monitoring to diagnose OSAS in patients with pulmonary comorbidities. OBJECTIVE: To assess the influence of suffering from COPD in the performance of an oximetry-based screening test for moderate-to-severe OSAS, both in the hospital and at home...
2017: PloS One
https://www.readbyqxmd.com/read/29173609/effects-of-patent-foramen-ovale-closure-on-obstructive-sleep-apnea-syndrome-pcosa-study
#20
Stephen P Hoole, Jules Hernández-Sánchez, William R Davies, Duncan C McNab, Patrick A Calvert, Bushra S Rana, Leonard M Shapiro, Michael G Davies
BACKGROUND: Previous studies have shown a higher prevalence of patent foramen ovale (PFO) in patients with obstructive sleep apnea syndrome (OSAS). Right to left shunting through a PFO may be encouraged by the respiratory physiology of OSAS, contributing to the disease pathophysiology. We assessed whether PFO closure would improve respiratory polygraphy parameters compared with baseline measurements in patients with OSAS. METHODS: Twenty-six patients with newly diagnosed OSAS and a moderate-large PFO (prevalence, 18% of 143 patients screened) were referred for PFO closure...
December 2017: Canadian Journal of Cardiology
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