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Obstructive sleep apnea hypopnea syndrome

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https://www.readbyqxmd.com/read/28927491/effectiveness-of-intranasal-sodium-hyaluronate-in-mitigating-adverse-effects-of-nasal-continuous-positive-airway-pressure-therapy
#1
(no author information available yet)
BACKGROUND: Nasal continuous positive airway pressure (CPAP) in moderate-to-severe cases of obstructive sleep apnea cancause nasal discomfort and other undesirable problems. OBJECTIVE: The aim of our study was to test the effects of sodium hyaluronate on nasal problems that patients experienced in their daily lives, sleepiness, nasal resistance to airflow, nasal mucociliary clearance, changes in inflammatory markers, and compliance to CPAP in three groups of patients with obstructive sleep apnea syndrome on CPAP therapy...
September 19, 2017: American Journal of Rhinology & Allergy
https://www.readbyqxmd.com/read/28924439/corneal-neovascularization-with-associated-lipid-keratopathy-in-a-patient-with-obstructive-sleep-apnea-hypopnea-syndrome-using-a-continuous-positive-airway-pressure-machine
#2
Konstantinos Oikonomakis, Myrsini Petrelli, Konstantinos Andreanos, Andreas Mouchtouris, Petros Petrou, Ilias Georgalas, Dimitrios Papaconstantinou, George Kymionis
OBJECTIVE: To report a case of corneal neovascularization with secondary lipid keratopathy in a patient treated with continuous positive airway pressure (CPAP) for obstructive sleep apnea-hypopnea syndrome (OSAHS). CASE REPORT: A 49-year-old male had been diagnosed with obstructive sleep apnea syndrome 10 years ago and has been treated with the application of a CPAP machine during night sleep ever since. For the past year, the patient had been complaining for ocular irritation and excessive tearing of the left eye on awakening...
May 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28915135/otolaryngologic-management-of-down-syndrome-patients-what-is-new
#3
Ethan C Bassett, Mary F Musso
PURPOSE OF REVIEW: The management of children with Down syndrome as it pertains to the otolaryngologist continues to evolve. Obstructive sleep apnea (OSA) has dominated the recent literature, but other topics including hearing loss, swallowing, and perioperative considerations are also reported. RECENT FINDINGS: The prevalence of OSA in children with Down syndrome ranges from 57 to 73% in certain cohorts, and, whereas adentonsillectomy can decrease Apnea-Hypopnea Index, up to 80% may have persistent OSA...
September 14, 2017: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/28912855/effect-of-transoral-endoscopic-adenoidectomy-on-peripheral-blood-t-lymphocyte-subsets-in-children-with-obstructive-sleep-apnea-hypopnea-syndrome-and-its-treatment-strategy
#4
Na Yang, Yaofeng Ji, Yin Liu
The objective of the present study was to investigate the effect of transoral endoscopic adenoidectomy on peripheral blood T lymphocyte subsets in pediatric patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) and its treatment strategy. Ninety-eight pediatric patients with adenoidal hypertrophy associated with OSAHS admitted to the Department of Otolaryngology, Xuzhou Children's Hospital were selected. After admission, patients received perfected 24 h polysomnogram monitoring, routine blood examination, fasting blood biochemistry examination, T-lymphocyte subset count, 24 h ambulatory blood pressure monitoring, and nasopharyngeal computed tomography...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28910920/-high-flow-nasal-cannula-in-obstructive-sleep-apnea-hypopnea-syndrome
#5
X Wu, W Cao, S Y Wang
No abstract text is available yet for this article.
September 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28910915/-assessment-of-sleep-disordered-breathing-using-hypoxia-index
#6
Y X Du, Y M Zeng, Z B Zhou, L M Huang
Objective: To analyze the clinical significance of hypoxia index (HI) in assessing the severity of hypoxemia in obstructive sleep apnoea hypopnea syndrome(OSAHS). Methods: A total of 127 patients with a complaint of snoring visiting our hospital were recruited from February 2014 to January 2016. All patients received polysomnography (PSG) test. The PSG results were analyzed by a technician and the SpO(2) data were analyzed by a pre-designed computer software. The patients were grouped according to apnea hypopnea index (AHI) and lowest oxygen saturation (LSpO(2)) respectively...
September 12, 2017: Chinese Journal of Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28910892/-study-on-pharyngeal-wall-floppiness-of-patients-with-obstructive-sleep-apnea-hypopnea-syndrome-attributable-to-non-structural-factors
#7
Z Q Lin, K L Jiang, L Zhao, S N Li, S Shao, W Qian, Z Z Tao
Objective: Acoustic pharyngealmetry technology is utilized to evaluate the change and clinical significance of obstructive sleep apnea-hypopnea syndrome (OSAHS) patients caused by non-upper airway structural factor and normal individuals' PWF(pharyngeal wall floppiness). Methods: Acoustic pharyngealmetry instrument of Ecconvision was utilized to examine 102 OSAHS patients and 50 normal individuals, separately recorded their volume of pharyngeal cavity in sit or supine position, calculated PWF in sit or supine position, and SPSS 12...
September 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28910165/peripapillary-choroidal-thickness-and-retinal-nerve-fiber-layer-in-untreated-patients-with-obstructive-sleep-apnea-hypopnea-syndrome-a-case-control-study
#8
Serpil Yazgan, Fatma Erboy, Haci Ugur Celik, Tacettin Ornek, Suat Hayri Ugurbas, Firuzan Kokturk, Orhan Ayar, Mehmet Orcun Akdemir, Erkan Celik
PURPOSE: To evaluate peripapillary choroidal thickness (PPCT), central macular choroidal thickness (CMCT), and retinal nerve fiber layer (RNFL) thickness in untreated patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). METHODS: This prospective, randomized, and comparative study was conducted in a university ophthalmology clinic. 106 eyes of 106 patients with OSAHS and 44 eyes of 44 healthy individuals were evaluated in this study. Only right eyes were evaluated...
September 14, 2017: Current Eye Research
https://www.readbyqxmd.com/read/28906336/interobserver-consistency-of-drug-induced-sleep-endoscopy-in-diagnosing-obstructive-sleep-apnea-using-a-vote-classification-system
#9
Ahmet Altintaş, Burak Olgun, Yakup Yegin, Mustafa Çelik, Kamil Hakan Kaya, Arzu Karaman Koç, Fatma Tülin Kayhan
OBJECTIVES: To explore the interobserver consistency of drug-induced sleep endoscopy (DISE) for patients with obstructive sleep apnea syndrome (OSAS) and review the current literature. METHODS: In total, 55 patients with an apnea-hypopnea index >5, as determined by on overnight sleep study, were included in this study, 45 males and 10 females, with an average age of 46.87 ± 10.06 years old (range, 19-71). For all OSAS patients, DISE was performed by the same surgeon, which was recorded digitally...
September 12, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28901415/effect-of-continuous-positive-airway-pressure-therapy-on-inflammatory-cytokines-and-atherosclerosis-in-patients-with-obstructive-sleep-apnea-syndrome
#10
Fa Jin, Jiannan Liu, Xiuwei Zhang, Wei Cai, Yuqiong Zhang, Wei Zhang, Jian Yang, Gan Lu, Xilong Zhang
Obstructive sleep apnea syndrome (OSAS) is known to be a risk factor for atherosclerosis (AS), derived from a series of chronic inflammatory reactions caused by hypoxia. However, the association between chronic inflammation and high blood pressure caused by hypoxia remains to be fully elucidated. The aim of the present study was to investigate the effect of continuous positive airway pressure (CPAP) therapy on inflammatory cytokines and AS. A total of 100 patients with OSAS and 50 healthy control subjects were enrolled...
August 30, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28901388/inhibitory-effects-of-17%C3%AE-estradiol-or-a-resveratrol-dimer-on-hypoxia-inducible-factor-1%C3%AE-in-genioglossus-myoblasts-involvement-of-er%C3%AE-and-its-downstream-p38%C3%A2-mapk-pathways
#11
Yuanyuan Li, Yuehua Liu, Yun Lu, Bingjiao Zhao
Deficiency in the functioning of the genioglossus, which is one of the upper airway dilator muscles, is an important cause of obstructive sleep apnea/hypopnea syndrome (OSAHS). Estrogens have been reported to inhibit hypoxia-inducible factor-1α (HIF-1α) expression in hypoxia, regulating its target genes and exerting protective effects on the genioglossus in chronic intermittent hypoxia (CIH). This study aimed to investigate the role of 17β-estradiol (E2) and a resveratrol dimer (RD) on HIF-1α and the underlying mechanism...
September 7, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28901049/arousal-responses-to-respiratory-events-during-sleep-the-role-of-pulse-wave-amplitude
#12
Marcello Bosi, Giulia Milioli, Silvia Riccardi, Andrea Melpignano, Anna E Vaudano, Pietro Cortelli, Venerino Poletti, Liborio Parrino
The study aims at assessing the changes in electroencephalography (as measured by the A-phases of cyclic alternating pattern) and autonomic activity (based on pulse wave amplitude) at the recovery of airway patency in patients with obstructive sleep apnea syndrome. Analysis of polysomnographic recordings from 20 male individuals with obstructive sleep apnea syndrome was carried out in total sleep time, non-rapid eye movement and rapid eye movement sleep. Scoring quantified the combined occurrence (time range of 4 s before and 4 s after respiratory recovery) or separate occurrence of A-phases (cortical activation), and pulse wave amplitude drops (below 30%) to apneas, hypopneas or flow limitation events...
September 12, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28895429/effectiveness-of-adenotonsillectomy-and-risk-of-velopharyngeal-insufficiency-in-children-with-prader-willi-syndrome
#13
Reema Padia, Harlan Muntz, Kathleen Pfeffer, Jeremy Meier
OBJECTIVES: (1) Review effectiveness of adenotonsillectomy (T&A) for obstructive sleep apnea (OSA) in children with Prader-Willi syndrome (PW). (2) Examine the incidence of velopharyngeal insufficiency (VPI) after T&A in this population. (3) Compare outcomes of T&A in PW and Trisomy 21 (T21) patients. METHODS: Outcomes after T&A in a PW cohort were retrospectively reviewed and compared to those in patients with T21. RESULTS: The study cohort included 22 PW patients...
September 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28884388/circulating-c3-and-glucose-metabolism-abnormalities-in-patients-with-osahs
#14
Xiaoxia Lu, Xiao Wang, Ting Xu, Yuan Feng, Yufeng Wang, Zechuan Cai, Bing Cao, Taoping Li
PURPOSE: Obstructive sleep apnea hypopnea syndrome (OSAHS) is a common breathing disorder during sleep characterized by multiple disease roots, including disorders of complement and glycometabolism. And the main purpose of the present study is to make clear the effect of complement C3 on glucose metabolism abnormalities in patients with OSAHS. METHODS: This was a cross-sectional study. Two hundred six patients, mean age 44.58 ± 11.84 years and 26 female patients (26/206), had been suspected with OSAHS and underwent overnight polysomnography...
September 7, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28872361/prevalence-of-sleep-apnea-and-cardiovascular-risk-factors-in-patients-with-hypertension-in-a-day-hospital-model
#15
Eduardo Borsini, Magalí Blanco, Martín Bosio, Marcela Schrappe, Glenda Ernst, Daniela Nosetto, Nazarena Gaggioli, Alejandro Salvado, Osvaldo Manuale, Miguel Schiavone
INTRODUCTION: To identify patients at risk for obstructive sleep apnea (OSA) syndrome at a specialized hypertension center, we administered questionnaires and used respiratory polygraphy (RP). RESULTS: We studied 168 patients (64.8% men and 35.2% women). Patients' body mass index (BMI) was 34.7 ± 6.79 and Epworth Sleepiness Scale (ESS) scores were 8.01 for male and 8.92 for women (p = 0.69). RP recordings revealed AHI (Apnea-Hypopnea Index) of 18.03 ± 15...
September 5, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28872099/impact-of-bariatric-surgery-on-obstructive-sleep-apnoea-hypopnea-syndrome-in-morbidly-obese-patients
#16
Pratyusha Priyadarshini, Vijay Pal Singh, Sandeep Aggarwal, Harshit Garg, Sanjeev Sinha, Randeep Guleria
BACKGROUND: Obstructive sleep apnea (OSA) is commonly associated with morbid obesity. Weight loss following bariatric surgery results in resolution or improvement of OSA. However, few studies have done objective assessment of the impact of bariatric surgery on OSA. OBJECTIVE: The aim of this study was to assess the outcome of bariatric surgery on OSA. SETTING: The study was conducted in the teaching institution of a tertiary care centre. METHODS: Twenty-seven morbidly obese patients seeking bariatric surgery were administered Epworth Sleepiness Scale (ESS) health questionnaire and subjected to overnight polysomnography...
October 2017: Journal of Minimal Access Surgery
https://www.readbyqxmd.com/read/28865812/efficacy-of-rapid-maxillary-expansion-in-the-treatment-of-obstructive-sleep-apnea-syndrome-a-systematic-review-with-meta-analysis
#17
Francisco Vale, Mariana Albergaria, Eunice Carrilho, Inês Francisco, Adriana Guimarães, Francisco Caramelo, Luísa Maló
OBJECTIVE: The objective of this study was to assess the efficacy of rapid maxillary expansion (RME) in the treatment of OSAS in children and adolescents. METHODS: Five electronic databases were searched systematically: PubMed, Web of Science, LILACS, Embase and Cochrane Library. SELECTION CRITERIA: Randomized controlled trials, nonrandomized controlled trials, cohort studies, and systematic reviews published in English, Spanish, or Portuguese between January 2000 and December 2016, performed on children and adolescents younger than 18 years with OSAS who underwent RME, and assessing RME efficacy as measured by the Apnea-Hypopnea Index (AHI) normalization were included...
September 2017: Journal of Evidence-based Dental Practice
https://www.readbyqxmd.com/read/28865140/the-comparison-of-nasal-surgery-and-cpap-on-daytime-sleepiness-in-patients-with-osas
#18
M Tagaya, H Otake, K Suzuki, F Yasuma, H Yamamoto, A Noda, Y Nishimura, M Sone, T Nakashima, S Nakata
OBJECTIVE: Residual sleepiness after continuous positive airway pressure (CPAP) is a critical problem in some patients with obstructive sleep apnea syndrome (OSAS). However, nasal surgery is likely to reduce daytime sleepiness and feelings of unrefreshed sleep. The aim of this study is to clarify the effects of nasal surgery and CPAP on daytime sleepiness. METHODOLOGY: This is a retrospective and matched-case control study. The participants were consecutive 40 patients with OSAS who underwent nasal surgery (Surgery group) and 40 matched patients who were treated with CPAP (CPAP group)...
September 1, 2017: Rhinology
https://www.readbyqxmd.com/read/28863405/phantom-study-evaluating-detection-of-simulated-upper-airway-occlusion-using-piezoelectric-ultrasound-transducers
#19
Mohammad Al-Abed, Peter Antich, Donald E Watenpaugh, Khosrow Behbehani
Obstructive sleep apnea/hypopnea syndrome (OSAHS) is characterized by repetitive narrowing or full collapse of the upper airway concomitant with continued respiratory effort during sleep lasting 10s or more. OSAHS is the most prevalent form of sleep-disordered breathing, affecting more than 17% of the middle-aged U.S. POPULATION: Hence, many individuals need to be tested for having OSAHS. Currently, detection of airway occlusion due to OSAHS is achieved by indirect measurements, often requiring multiple sensor types, such as a flow transducer combined with chest and abdomen plethysmography...
August 24, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28862662/snorap-a-device-for-the-correction-of-impaired-sleep-health-by-using-tactile-stimulation-for-individuals-with-mild-and-moderate-sleep-disordered-breathing
#20
Mete Yağanoğlu, Murat Kayabekir, Cemal Köse
Sleep physiology and sleep hygiene play significant roles in maintaining the daily lives of individuals given that sleep is an important physiological need to protect the functions of the human brain. Sleep disordered breathing (SDB) is an important disease that disturbs this need. Snoring and Obstructive Sleep Apnea Syndrome (OSAS) are clinical conditions that affect all body organs and systems that intermittently, repeatedly, with at least 10 s or more breathing stops that decrease throughout the night and disturb sleep integrity...
September 1, 2017: Sensors
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