Gerard Limerick, Dana K Christo, Jennifer Tram, Roya Moheimani, John Manor, Krishnan Chakravarthy, Jay Karri, Paul J Christo
PURPOSE OF REVIEW: This review presents the most current information about the epidemiology of complex regional pain syndrome (CRPS), classification and diagnostic criteria, childhood CRPS, subtypes, pathophysiology, conventional and less conventional treatments, and preventive strategies. RECENT FINDINGS: CRPS is a painful disorder with multifactorial pathophysiology. The data describe sensitization of the central and peripheral nervous systems, inflammation, possible genetic factors, sympatho-afferent coupling, autoimmunity, and mental health factors as contributors to the syndrome...
September 2023: Current Pain and Headache Reports