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Sensory stimulation

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https://www.readbyqxmd.com/read/28227899/peripheral-sensory-stimulation-is-neuroprotective-in-a-rat-photothrombotic-ischemic-stroke-model
#1
Aishwarya Bandla, Chua Le Teng Sherry, Frances Lim, Chan Kim Chuan, Lun-De Liao, Nitish V Thakor, Aishwarya Bandla, Chua Le Teng Sherry, Frances Lim, Chan Kim Chuan, Lun-De Liao, Nitish V Thakor, Lun-De Liao, Nitish V Thakor, Frances Lim, Chua Le Teng Sherry, Aishwarya Bandla, Chan Kim Chuan
Ischemic stroke is one of the leading causes of death and disability in the world. Thrombolytic therapy using recombinant tissue plasminogen activator (rtPA), the only FDA-approved drug for acute ischemia, is limited by a narrow therapeutic time window and risk of hemorrhage. There is a serious need for a neuroprotective therapy which is clinically viable. We earlier demonstrated that peripheral sensory stimulation (PSS) is a potential therapeutic intervention for hyperacute ischemia resulting in recovery of neurovascular functions when administered immediately following ischemia onset in a rat model...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227745/numerical-simulation-of-multipolar-configuration-and-prepulse-technique-to-obtain-spatially-reverse-recruitment-order
#2
Melissa Dali, Olivier Rossel, David Guiraud, Melissa Dali, Olivier Rossel, David Guiraud, Melissa Dali, Olivier Rossel, David Guiraud
In the context of functional electrical stimulation of peripheral nerves, the control of a specific motor or sensory functions may need selective stimulation to target the desired effect without others. In implanted stimulation, spatial selectivity is obtained using multipolar CUFF electrodes with specific spread of the current over each contact. Furthermore, electrical stimulation recruits large fibers before small ones, whereas the targeted function could be elicited by a specific fiber type i.e. fiber diameter...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227568/system-to-induce-and-measure-embodiment-of-an-artificial-hand-with-programmable-convergent-visual-and-tactile-stimuli
#3
Heather L Benz, Talia R Sieff, Mahsa Alborz, Kimberly Kontson, Elizabeth Kilpatrick, Eugene F Civillico, Heather L Benz, Talia R Sieff, Mahsa Alborz, Kimberly Kontson, Elizabeth Kilpatrick, Eugene F Civillico, Kimberly Kontson, Heather L Benz, Talia R Sieff, Elizabeth Kilpatrick, Eugene F Civillico, Mahsa Alborz
The sense of prosthesis embodiment, or the feeling that the device has been incorporated into a user's body image, may be enhanced by emerging technology such as invasive electrical stimulation for sensory feedback. In turn, prosthesis embodiment may be linked to increased prosthesis use and improved functional outcomes. We describe the development of a tool to assay artificial hand embodiment in a quantitative way in people with intact limbs, and characterize its operation. The system delivers temporally coordinated visual and tactile stimuli at a programmable latency while recording limb temperature...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227563/a-study-on-the-effect-of-multisensory-stimulation-in-behaving-rats
#4
Marianna Semprini, Fabio Boi, Valter Tucci, Alessandro Vato, Marianna Semprini, Fabio Boi, Valter Tucci, Alessandro Vato, Fabio Boi, Valter Tucci, Marianna Semprini, Alessandro Vato
This study explored the psychophysical effects of intracortical microstimulation (ICMS) coupled to auditory stimulation during a behavioral detection task in rats. ICMS directed to the sensory areas of the cortex can be instrumental in facilitating operant conditioning behavior. Moreover, multisensory stimulation promotes learning by enabling the subject to access multiple information channels. However, the extent to which multisensory information can be used as a cue to make decisions has not been fully understood...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227561/mirror-therapy-combined-with-functional-electrical-stimulation-for-rehabilitation-of-stroke-survivors-ankle-dorsiflexion
#5
Ghadir Salhab, Ahmad Rifaii Sarraj, Soha Saleh, Ghadir Salhab, Ahmad Rifaii Sarraj, Soha Saleh, Ahmad Rifaii Sarraj, Ghadir Salhab, Soha Saleh
This study investigates the effect of combining both mirror therapy with Electrical Stimulation (ES) on improvement of the function of lower extremity compared to conventional therapy. 18 stroke survivors (sub acute stage) were recruited, 9 of them were randomly assigned to receive conventional treatment and another 9 started the mirror therapy combined with ES treatment. Duration of each session in both interventions was 50 minutes, done 4 times per week over two weeks. After 2 weeks, subjects took one week rest before switching they type of treatment; those started with conventional therapy continued with mirror therapy combined with ES, and vice versa...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227554/cortical-excitability-effects-of-stimulation-intensity-change-speed-during-nmes
#6
Shenglong Jiang, Zhongpeng Wang, Weibo Yi, Feng He, Shuang Liu, Hongzhi Qi, Dong Ming, Shenglong Jiang, Zhongpeng Wang, Weibo Yi, Feng He, Shuang Liu, Hongzhi Qi, Dong Ming, Shuang Liu, Shenglong Jiang, Zhonapeng Wang, Dong Ming, Feng He, Qi Hongzhi, Weibo Yi
Rehabilitation method of motor dysfunction is a challenging issue of neural rehabilitation. Neuromuscular electrical stimulation (NMES) has been frequently used in rehabilitation therapy to improve neural recovery such as stroke and spinal cord injury. Stimulus, acting on sensorimotor neural system components, resulted in the increased cortical excitability which accompanied with motor performance improvement. Stimulus information conveyed by sensory system included below four elementary attributes: modality, location, intensity, and timing...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227393/an-integrated-neuroprotective-intervention-for-brain-ischemia-validated-by-ecog-fpam
#7
Yu-Hang Liu, Lun-De Liao, Su Jing Chan, Aishwarya Bandla, Nitish V Thakor, Yu-Hang Liu, Lun-De Liao, Su Jing Chan, Aishwarya Bandla, Nitish V Thakor, Yu-Hang Liu, Aishwarya Bandla, Nitish V Thakor, Su Jing Chan, Lun De Liao
Brain ischemia is a neurological deficit caused by a reduction in the blood supply to tissue, and one of the leading causes of disability in the world. Currently, the most well-known therapeutic agent for ischemia recovery is recombinant tissue plasminogen activator (rtPA), but it is viable for only a small portion (approximately 3.6%) of ischemic patients and may cause side effects such as tissue damage. Thus, introducing a new therapeutic concept for ischemia, we proposed an integrated intervention combining global and focal stimulations in this article...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227367/statistical-identification-of-stimulus-activated-network-nodes-in-multi-neuron-voltage-sensitive-dye-optical-recordings
#8
Elham Fathiazar, Jorn Anemuller, Jutta Kretzberg, Elham Fathiazar, Jorn Anemuller, Jutta Kretzberg, Elham Fathiazar, Jutta Kretzberg, Jorn Anemuller
Voltage-Sensitive Dye (VSD) imaging is an optical imaging method that allows measuring the graded voltage changes of multiple neurons simultaneously. In neuroscience, this method is used to reveal networks of neurons involved in certain tasks. However, the recorded relative dye fluorescence changes are usually low and signals are superimposed by noise and artifacts. Therefore, establishing a reliable method to identify which cells are activated by specific stimulus conditions is the first step to identify functional networks...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227180/electrical-stimulation-of-the-saphenous-nerve-in-anesthetized-rats-a-novel-therapeutic-approach-to-treating-overactive-bladder
#9
Zainab Moazzam, Paul B Yoo, Zainab Moazzam, Paul B Yoo, Paul B Yoo, Zainab Moazzam
Posterior Tibial Nerve Stimulation (PTNS) is a minimally invasive yet effective therapy for treating overactive bladder (OAB) symptoms with electrical stimulations applied at 20 Hz coupled with amplitudes approximating the foot-twitch threshold (T). However, pre-clinical studies indicate that PTNS-evoked bladder reflexes require stimulation amplitudes exceeding 2T. The objective of this work was to evaluate the presence of secondary low-threshold sensory pathways in the hind-limb region that can be a potential target of activation during clinical PTNS set-up...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226860/an-implantable-designed-for-human-use-peripheral-nerve-stimulation-and-recording-system-for-advanced-prosthetics
#10
John R Lachapelle, Caroline K Bjune, Alexander L Kindle, Andrew Czarnecki, John R Burns, Julianne E Grainger, Carlos A Segura, Brian D Nugent, Tirunelveli S Sriram, Philip D Parks, Edward Keefer, Jonathan Cheng, John R Lachapelle, Caroline K Bjune, Alexander L Kindle, Andrew Czarnecki, John R Burns, Julianne E Grainger, Carlos A Segura, Brian D Nugent, Tirunelveli S Sriram, Philip D Parks, Edward Keefer, Jonathan Cheng, John R Lachapelle, Edward Keefer, Alexander L Kindle, Julianne E Grainger, John R Burns, Philip D Parks, Jonathan Cheng, Andrew Czarnecki, Brian D Nugent, Carlos A Segura, Tirunelveli S Sriram, Caroline K Bjune
Complex suture prostheses that deliver sensory and position feedback require a more sophisticated integration with the human user. Here a micro-size active implantable system that provides many-degree-of-freedom neural feedback in both sensory stimulation and motor control is shown, as one potential human-use solution in DARPA's HAPTIX program. Various electrical and mechanical challenge and solutions in meeting both sensory /motor performance as well as ISO 14708 FDA-acceptable human use in an aspirin-size active implementation are discussed...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226857/development-of-a-closed-loop-system-for-tremor-suppression-in-patients-with-parkinson-s-disease
#11
F L Xu, M Z Hao, S Q Xu, Z X Hu, Q Xiao, N Lan, F L Xu, M Z Hao, S Q Xu, Z X Hu, Q Xiao, N Lan, S Q Xu, Z X Hu, Q Xiao, M Z Hao, N Lan, F L Xu
More than 70% of patients suffering Parkinson's disease (PD) exhibit resting tremor in their extremities, hampering their ability to perform daily activities. Based on our earlier studies on corticospinal transmission of tremor signals [10,11], we hypothesize that cutaneous afferents evoked by surface stimulation can produce an inhibitory effect on propriospinal neurons (PN), which in turn will suppress tremor signals passing through the PN. This paper presents the development of a closed-loop system for tremor suppression by transcutaneous electrical nerve stimulation (TENS) of sensory fibers beneath the skin...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226494/upper-extremity-prosthesis-user-perspectives-on-unmet-needs-and-innovative-technology
#12
Heather L Benz, Jia Yao, Laura Rose, Okan Olgac, Karen Kreutz, Anindita Saha, Eugene F Civillico, Heather L Benz, Jia Yao, Laura Rose, Okan Olgac, Karen Kreutz, Anindita Saha, Eugene F Civillico, Laura Rose, Heather L Benz, Anindita Saha, Okan Olgac, Eugene F Civillico, Karen Kreutz, Jia Yao
The needs of individuals with upper limb amputation and congenital limb difference are not being fully met by current prostheses, as evidenced by prosthesis rejection, non-wear, and user reports of pain and challenging activities. Emerging technologies such as dexterous sensorized robotic limbs, osseointegrated prostheses, implantable EMG electrodes, and electrical stimulation for sensory feedback have the potential to address unmet needs, but pose additional risks. We plan to assess upper limb prosthesis user needs and perspectives on these new benefits and risks using an extensive quantitative survey...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224454/effects-of-sustained-otolith-only-stimulation-on-post-rotational-nystagmus
#13
Aasef G Shaikh, David Solomon
Constant velocity rotations in darkness evoke vestibulo-ocular reflex in form of pre- and post-rotational nystagmus under cerebellar supervision. Reorientation of the head with respect to gravity, stimulating otolith and semicircular canal, during post-rotational phase rapidly suppresses the post-rotational nystagmus. We asked if pure otolith stimulation without semicircular canal signal is sufficient for the suppression of post-rotational nystagmus. The experimental paradigm comprised of on-axis rotations in the horizontal plane when the subject was sitting upright, followed by a novel stimulus that combined off-axis centrifugation in the horizontal plane with amplitude matched, yet out-of-phase, on-axis horizontal rotation-double centrifugation...
February 21, 2017: Cerebellum
https://www.readbyqxmd.com/read/28223033/children-with-asd-show-links-between-aberrant-sound-processing-social-symptoms-and-atypical-auditory-interhemispheric-and-thalamocortical-functional-connectivity
#14
Annika C Linke, R Joanne Jao Keehn, Ellyn B Pueschel, Inna Fishman, Ralph-Axel Müller
Autism spectrum disorder (ASD) is a complex and prevalent neurodevelopmental disorder characterized by social and communicative deficits, as well as repetitive behaviors and atypical sensitivity to sensory stimulation. Alterations in network connectivity are widely recognized, but their interplay with social and sensory symptoms remains largely unclear. Here, functional magnetic resonance imaging and diagnostic and behavioral assessments were used in a cohort of children and adolescents with ASD (n=40) and matched typically developing (TD, n=38) controls to examine the relation between auditory processing, interhemispheric and thalamocortical network connectivity, and social-behavioral symptom severity...
January 16, 2017: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/28222563/afferent-electrical-stimulation-during-cycling-improves-spinal-processing-of-sensorimotor-function-after-incomplete-spinal-cord-injury
#15
Stefano Piazza, Diego Serrano-Muñoz, Julio Gómez-Soriano, Diego Torricelli, Antonio Segura-Fragosa, José Luis Pons, Julian Taylor
OBJECTIVE: Appropriate afferent feedback delivery during the execution of motor tasks is important for rehabilitation after incomplete spinal cord injury (iSCI). However, during leg-cycling therapy, the plantar afferent feedback is minimal. We hypothesize that the augmentation of sensory input by combining cycling with a locomotor-like stimulation of plantar cutaneous innervations (ES-cycling), might help to restore proper spinal processing of sensorimotor function. METHODS: 13 non-injured subjects and 10 subjects with iSCI performed 10 minutes of cycling and, on another session, of ES-cycling...
February 10, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222553/dual-afferent-sensory-input-training-for-voluntary-movement-after-stroke-a-pilot-randomized-controlled-study
#16
Seahyun Bae, Kyung-Yoon Kim
BACKGROUND: Stimulation through afferent sensory input is necessary to improve voluntary functional movement in stroke patients. OBJECTIVES: Dual-afferent sensory input, which combines electromyography-triggered functional electric stimulation (ETFES) and action observation, was investigated to determine its effects on voluntary movements in stroke patients. METHODS: This study was conducted on 18 patients with left hemiplegia diagnosed between 6 and 24 months prior...
February 8, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28222543/anodal-cerebellar-tdcs-modulates-lower-extremity-pain-perception
#17
Manuel Pereira, Basil Rafiq, Einul Chowdhury, Jacqueline Babayev, HyunJi Boo, Rowan Metwaly, Sandilya Priam, Eileen Chusid, Fortunato Battaglia
BACKGROUND: Previous studies have investigated the use of transcranial direct current stimulation (tDCS) for pain management. The studies investigating therapeutic neuromodulation with tDCS for lower extremity pain are scarce and inconclusive. OBJECTIVE: The aim of the present study was to analyze the effects of cerebellar tDCS on lower extremity sensory and pain thresholds in healthy volunteers. METHODS: This was a single-blind crossover repeated-measure study...
January 31, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28220715/a-systematic-review-of-mechanisms-of-gait-speed-change-post-stroke-part-1-spatiotemporal-parameters-and-asymmetry-ratios
#18
Elizabeth C Wonsetler, Mark G Bowden
BACKGROUND: In walking rehabilitation trials, self-selected walking speed (SSWS) has emerged as the dominant outcome measure to assess walking ability. However, this measure cannot differentiate between recovery of impaired movement and compensation strategies. Spatiotemporal variables and asymmetry ratios are frequently used to quantify gait deviations and are hypothesized markers of recovery. OBJECTIVES: The purpose of this review is to investigate spatiotemporal variables and asymmetry ratios as mechanistic recovery measures in physical therapy intervention studies post-stroke...
February 21, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/28220063/vibrotactile-discrimination-training-affects-brain-connectivity-in-profoundly-deaf-individuals
#19
Andrés A González-Garrido, Vanessa D Ruiz-Stovel, Fabiola R Gómez-Velázquez, Hugo Vélez-Pérez, Rebeca Romo-Vázquez, Ricardo A Salido-Ruiz, Aurora Espinoza-Valdez, Luis R Campos
Early auditory deprivation has serious neurodevelopmental and cognitive repercussions largely derived from impoverished and delayed language acquisition. These conditions may be associated with early changes in brain connectivity. Vibrotactile stimulation is a sensory substitution method that allows perception and discrimination of sound, and even speech. To clarify the efficacy of this approach, a vibrotactile oddball task with 700 and 900 Hz pure-tones as stimuli [counterbalanced as target (T: 20% of the total) and non-target (NT: 80%)] with simultaneous EEG recording was performed by 14 profoundly deaf and 14 normal-hearing (NH) subjects, before and after a short training period (five 1-h sessions; in 2...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28219984/motor-neurons-tune-premotor-activity-in-a-vertebrate-central-pattern-generator
#20
Kristy J Lawton, Wick M Perry, Ayako Yamaguchi, Erik Zornik
Central patterns generators (CPGs) are neural circuits that drive rhythmic motor output without sensory feedback. Vertebrate CPGs are generally believed to operate in a top-down manner in which premotor interneurons activate motor neurons that in turn drive muscles. In contrast, the frog (Xenopus laevis) vocal CPG contains a functionally unexplored neuronal projection from the motor nucleus to the premotor nucleus, indicating a recurrent pathway that may contribute to rhythm generation. In this study we characterized the function of this bottom-up connection...
February 20, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
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