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Brain connectivity

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https://www.readbyqxmd.com/read/29149201/the-influence-of-filtering-and-downsampling-on-the-estimation-of-transfer-entropy
#1
Immo Weber, Esther Florin, Michael von Papen, Lars Timmermann
Transfer entropy (TE) provides a generalized and model-free framework to study Wiener-Granger causality between brain regions. Because of its nonparametric character, TE can infer directed information flow also from nonlinear systems. Despite its increasing number of applications in neuroscience, not much is known regarding the influence of common electrophysiological preprocessing on its estimation. We test the influence of filtering and downsampling on a recently proposed nearest neighborhood based TE estimator...
2017: PloS One
https://www.readbyqxmd.com/read/29149191/resting-state-fmri-in-sleeping-infants-more-closely-resembles-adult-sleep-than-adult-wakefulness
#2
Anish Mitra, Abraham Z Snyder, Enzo Tagliazucchi, Helmut Laufs, Jed Elison, Robert W Emerson, Mark D Shen, Jason J Wolff, Kelly N Botteron, Stephen Dager, Annette M Estes, Alan Evans, Guido Gerig, Heather C Hazlett, Sarah J Paterson, Robert T Schultz, Martin A Styner, Lonnie Zwaigenbaum, Bradley L Schlaggar, Joseph Piven, John R Pruett, Marcus Raichle
Resting state functional magnetic resonance imaging (rs-fMRI) in infants enables important studies of functional brain organization early in human development. However, rs-fMRI in infants has universally been obtained during sleep to reduce participant motion artifact, raising the question of whether differences in functional organization between awake adults and sleeping infants that are commonly attributed to development may instead derive, at least in part, from sleep. This question is especially important as rs-fMRI differences in adult wake vs...
2017: PloS One
https://www.readbyqxmd.com/read/29148587/experimental-infection-by-yersinia-ruckeri-o1-biotype-2-induces-brain-lesions-and-neurological-signs-in-rainbow-trout-oncorhynchus-mykiss
#3
H K Strøm, M Ohtani, B Nowak, T S Boutrup, B Jones, M K Raida, A M Bojesen
Pathological manifestations in rainbow trout (Oncorhynchus mykiss) following experimental waterborne infection with Yersinia ruckeri serotype O1 biotype 2 (strain 07111224) were investigated. Rainbow trout were exposed to 8 × 10(7)  CFU/ml of Y. ruckeri by bath for 6 hr, and mortality was then monitored for 22 days post-infection (dpi). Organs were sampled at 3 dpi and also from moribund fish showing signs of severe systemic infection such as bleeding, exophthalmia or erratic swimming behaviour. Y. ruckeri was observed in the meninges and diencephalon of the brain, and lamina propria of olfactory organ at 3 dpi...
November 17, 2017: Journal of Fish Diseases
https://www.readbyqxmd.com/read/29147146/relationships-between-short-and-fast-brain-timescales
#4
Eva Déli, Arturo Tozzi, James F Peters
Brain electric activity exhibits two important features: oscillations with different timescales, characterized by diverse functional and psychological outcomes, and a temporal power law distribution. In order to further investigate the relationships between low- and high- frequency spikes in the brain, we used a variant of the Borsuk-Ulam theorem which states that, when we assess the nervous activity as embedded in a sphere equipped with a fractal dimension, we achieve two antipodal points with similar features (the slow and fast, scale-free oscillations)...
December 2017: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/29147142/analysis-of-functional-brain-connections-for-positive-negative-emotions-using-phase-locking-value
#5
Yasar Dasdemir, Esen Yildirim, Serdar Yildirim
In this study, we investigate the brain networks during positive and negative emotions for different types of stimulus (audio only, video only and audio + video) in [Formula: see text], and [Formula: see text] bands in terms of phase locking value, a nonlinear method to study functional connectivity. Results show notable hemispheric lateralization as phase synchronization values between channels are significant and high in right hemisphere for all emotions. Left frontal electrodes are also found to have control over emotion in terms of functional connectivity...
December 2017: Cognitive Neurodynamics
https://www.readbyqxmd.com/read/29146466/causal-mapping-of-emotion-networks-in-the-human-brain-framework-and-initial-findings
#6
Julien Dubois, Hiroyuki Oya, J Michael Tyszka, Matthew Howard, Frederick Eberhardt, Ralph Adolphs
Emotions involve many cortical and subcortical regions, prominently including the amygdala. It remains unknown how these multiple network components interact, and it remains unknown how they cause the behavioral, autonomic, and experiential effects of emotions. Here we describe a framework for combining a novel technique, concurrent electrical stimulation with fMRI (es-fMRI), together with a novel analysis, inferring causal structure from fMRI data (causal discovery). We outline a research program for investigating human emotion with these new tools, and provide initial findings from two large resting-state datasets as well as case studies in neurosurgical patients with electrical stimulation of the amygdala...
November 13, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29146376/wronger-than-wrong-graded-mapping-of-the-errors-of-an-avatar-in-the-performance-monitoring-system-of-the-onlooker
#7
G Spinelli, G Tieri, E F Pavone, S M Aglioti
EEG studies show that observing errors in one's own or others' actions triggers specific electro-cortical signatures in the onlooker's brain, but whether the brain error-monitoring system operates according to graded or discrete rules is still largely unknown. To explore this issue, we combined immersive virtual reality with EEG recording in participants who observed an avatar reaching-to-grasp a glass from a first-person perspective. The avatar could perform correct or erroneous actions. Erroneous grasps were defined as small or large depending on the magnitude of the trajectory deviation from the to-be-grasped glass...
November 13, 2017: NeuroImage
https://www.readbyqxmd.com/read/29146299/functional-connectivity-during-affective-mentalizing-in-criminal-offenders-with-psychotic-disorders-associations-with-clinical-symptoms
#8
Carla L Harenski, Vince D Calhoun, Juan R Bustillo, Brian W Haas, Jean Decety, Keith A Harenski, Michael F Caldwell, Gregory J Van Rybroek, Michael Koenigs, David M Thornton, Kent A Kiehl
Psychotic disorders are associated with neurobehavioral impairments in mental state attribution (mentalizing). These impairments are most severe in psychotic patients with elevated symptom levels, particularly negative and cognitive symptoms. There have been few studies of functional connectivity related to mentalizing in psychotic disorders and associations with symptoms. We conducted a functional MRI study of affective mentalizing in individuals with psychotic disorders and varying symptom levels (positive, negative, cognitive)...
November 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/29145416/two-is-better-than-one-the-effects-of-strategic-cooperation-on-intra-and-inter-brain-connectivity-by-fnirs
#9
Michela Balconi, Laurent Pezard, Jean-Louis Nandrino, Maria Elide Vanutelli
Inter-brain synchronization during joint actions is a core question in social neuroscience, and the differential contribution of intra- and inter-brain functional connectivity has yet to be clarified along with the role of psychological variables such as perceived self-efficacy. The cognitive performance and the neural activation underlying the execution of joint actions were recorded by functional Near-Infrared imaging during a synchronicity game. An 8-channel array of optodes was positioned over the frontal and prefrontal regions...
2017: PloS One
https://www.readbyqxmd.com/read/29145183/catastrophe-reaction-and-emotionalism
#10
Antonio Carota, Julien Bogousslavsky
The catastrophic reaction (CR; a disruptive and uncontrolled behavior triggered by anger, irritability, and hostility) and emotionalism (a condition of uncontrolled crying or laughing) are disorders of the emotional regulation and expression, the prevalence of which is underestimated in neurology. Their occurrence is an additional factor of poor outcome for neurologic patients. Although they have been recognized and completely described in their clinical manifestations more than a century ago, many issues remain unsolved regarding their pathogenesis and the respective role of the brain damage and psychological factors...
2018: Frontiers of Neurology and Neuroscience
https://www.readbyqxmd.com/read/29143980/white-matter-maturation-during-12-months-in-individuals-at-ultra-high-risk-for-psychosis
#11
K Krakauer, M Nordentoft, B Y Glenthøj, J M Raghava, D Nordholm, L Randers, L B Glenthøj, B H Ebdrup, E Rostrup
OBJECTIVE: The neurodevelopmental hypothesis of psychosis suggests that disrupted white matter (WM) maturation underlies disease onset. In this longitudinal study, we investigated WM connectivity and compared WM changes between individuals at ultra-high-risk for psychosis (UHR) and healthy controls (HCs). METHOD: Thirty UHR individuals and 23 HCs underwent MR diffusion tensor imaging before and after 12 months of non-manualized standard care. Positive and negative symptoms and level of functioning were assessed...
November 16, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29143911/decreased-interhemispheric-coordination-in-the-posterior-default-mode-network-and-visual-regions-as-trait-alterations-in-first-episode-drug-naive-major-depressive-disorder
#12
Wenbin Guo, Xilong Cui, Feng Liu, Jindong Chen, Guangrong Xie, Renrong Wu, Zhikun Zhang, Huafu Chen, Xiangyang Zhang, Jingping Zhao
Decreased homotopic connectivity has been implicated in the neurophysiology of major depressive disorder (MDD) with inconsistent findings. A combination of clinical and methodological variabilities may account for the inconsistency, and thus limiting the reproducibility of the findings. The present study aims to examine voxel-mirrored homotopic connectivity (VMHC) alterations in two independent samples of patients with first-episode, drug-naive MDD. The samples included 59 patients and 31 controls from Sample 1 and 29 patients and 24 controls from Sample 2...
November 16, 2017: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/29143409/chronnectome-fingerprinting-identifying-individuals-and-predicting-higher-cognitive-functions-using-dynamic-brain-connectivity-patterns
#13
Jin Liu, Xuhong Liao, Mingrui Xia, Yong He
The human brain is a large, interacting dynamic network, and its architecture of coupling among brain regions varies across time (termed the "chronnectome"). However, very little is known about whether and how the dynamic properties of the chronnectome can characterize individual uniqueness, such as identifying individuals as a "fingerprint" of the brain. Here, we employed multiband resting-state functional magnetic resonance imaging data from the Human Connectome Project (N = 105) and a sliding time-window dynamic network analysis approach to systematically examine individual time-varying properties of the chronnectome...
November 15, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29143307/considerations-in-performing-and-analyzing-the-responses-of-cortico-cortical-evoked-potentials-in-stereo-eeg
#14
REVIEW
David Prime, David Rowlands, Steven O'Keefe, Sasha Dionisio
This review aims to highlight key considerations when performing cortico-cortical evoked potentials (CCEPs) using stereo-electroencephalography (SEEG) for network mapping and show its clinical applicability to presurgical evaluations. The parameters for performing stimulation and safety aspects have been investigated in electrocorticography (ECoG) and deep brain stimulation (DBS), but not as extensively in SEEG. A review of current literature was performed, with an attempt made to emphasize practical insights from all modalities of intracranial stimulation...
November 16, 2017: Epilepsia
https://www.readbyqxmd.com/read/29143250/cliques-and-cavities-in-the-human-connectome
#15
Ann E Sizemore, Chad Giusti, Ari Kahn, Jean M Vettel, Richard F Betzel, Danielle S Bassett
Encoding brain regions and their connections as a network of nodes and edges captures many of the possible paths along which information can be transmitted as humans process and perform complex behaviors. Because cognitive processes involve large, distributed networks of brain areas, principled examinations of multi-node routes within larger connection patterns can offer fundamental insights into the complexities of brain function. Here, we investigate both densely connected groups of nodes that could perform local computations as well as larger patterns of interactions that would allow for parallel processing...
November 16, 2017: Journal of Computational Neuroscience
https://www.readbyqxmd.com/read/29143096/-neurofeedback-for-the-treatment-of-chronic-tinnitus-review-and-future-perspectives
#16
REVIEW
T Kleinjung, C Thüring, D Güntensperger, P Neff, M Meyer
Neurofeedback is a noninvasive neuromodulation technique employing real-time display of brain activity in terms of electroencephalography (EEG) signals to teach self-regulation of distinct patterns of brain activity or influence brain activity in a targeted manner. The benefit of this approach for control of symptoms in attention deficit disorders, hyperactivity, depression, and migraine has been proven. Studies in recent years have also repeatedly shown this treatment to improve tinnitus symptoms, although it has not become established as routine therapy...
November 15, 2017: HNO
https://www.readbyqxmd.com/read/29142739/classification-of-amyotrophic-lateral-sclerosis-disease-based-on-convolutional-neural-network-and-reinforcement-sample-learning-algorithm
#17
Abdulkadir Sengur, Yaman Akbulut, Yanhui Guo, Varun Bajaj
Electromyogram (EMG) signals contain useful information of the neuromuscular diseases like amyotrophic lateral sclerosis (ALS). ALS is a well-known brain disease, which can progressively degenerate the motor neurons. In this paper, we propose a deep learning based method for efficient classification of ALS and normal EMG signals. Spectrogram, continuous wavelet transform (CWT), and smoothed pseudo Wigner-Ville distribution (SPWVD) have been employed for time-frequency (T-F) representation of EMG signals. A convolutional neural network is employed to classify these features...
December 2017: Health Information Science and Systems
https://www.readbyqxmd.com/read/29142321/design-of-cultured-neuron-networks-in-vitro-with-predefined-connectivity-using-asymmetric-microfluidic-channels
#18
Arseniy Gladkov, Yana Pigareva, Daria Kutyina, Vladimir Kolpakov, Anton Bukatin, Irina Mukhina, Victor Kazantsev, Alexey Pimashkin
The architecture of neuron connectivity in brain networks is one of the basic mechanisms by which to organize and sustain a particular function of the brain circuitry. There are areas of the brain composed of well-organized layers of neurons connected by unidirectional synaptic connections (e.g., cortex, hippocampus). Re-engineering of the neural circuits with such a heterogeneous network structure in culture may uncover basic mechanisms of emergent information functions of these circuits. In this study, we present such a model designed with two subpopulations of primary hippocampal neurons (E18) with directed connectivity grown in a microfluidic device with asymmetric channels...
November 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29141024/quantifying-indices-of-short-and-long-range-white-matter-connectivity-at-each-cortical-vertex
#19
Maria Carmela Padula, Marie Schaer, Elisa Scariati, A Kadir Mutlu, Daniela Zöller, Maude Schneider, Stephan Eliez
Several neurodevelopmental diseases are characterized by impairments in cortical morphology along with altered white matter connectivity. However, the relationship between these two measures is not yet clear. In this study, we propose a novel methodology to compute and display metrics of white matter connectivity at each cortical point. After co-registering the extremities of the tractography streamlines with the cortical surface, we computed two measures of connectivity at each cortical vertex: the mean tracts' length, and the proportion of short- and long-range connections...
2017: PloS One
https://www.readbyqxmd.com/read/29140729/gene-expression-and-gene-associations-during-the-development-of-heart-failure-with-preserved-ejection-fraction-in-the-dahl-salt-sensitive-model-of-hypertension
#20
Jeffrey Yim, Hyokeun Cho, Simon W Rabkin
Gene expression and associations were examined in a model of heart failure with preserved ejection fraction (HFpEF), a condition with minimal effective treatment. Genes with at least two studies showing significant changes in Dahl rat with heart failure were examined by meta-analysis. Significantly increased in expression were iNOS, p47phox, ADM, ANP, OPN, ACE, MCP-1, GP91PHOX, ICAM-1, TGF-β1, CTGF, ET-1, p22phox, ETB, BNP, ETA, MMP13, Col1a1, MMP2, TIMP1, Col3a1, Il-1β, β-MHC, ECE1, MMP14, AGT, and MMP9...
November 15, 2017: Clinical and Experimental Hypertension: CHE
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