keyword
https://read.qxmd.com/read/36192059/platinum-carbon-dots-nanocomposites-from-palm-bunch-hydrothermal-synthesis-as-highly-efficient-peroxidase-mimics-for-ultra-low-h-2-o-2-sensing-platform-through-dual-mode-of-colorimetric-and-fluorescent-detection
#1
JOURNAL ARTICLE
Aphinan Saengsrichan, Pongtanawat Khemthong, Wanwitoo Wanmolee, Saran Youngjan, Jakkapop Phanthasri, Pariyapat Arjfuk, Pisut Pongchaikul, Sakhon Ratchahat, Pattaraporn Posoknistakul, Navadol Laosiripojana, Kevin C-W Wu, Chularat Sakdaronnarong
Detection of hydrogen peroxide and glucose in nanomolar level is crucial for point-of-care medical diagnosis. It has been reported that human's central nervous system diseases such as Alzheimer's disease, Parkinson's disease, and even amyotrophic lateral sclerosis, are presumably caused H2 O2 or reactive radical species (ROS). Sensing of H2 O2 released from human biofluids, tissues, organ from metabolism disorder at ultra-low concentration assists for early identification of severe diabetis mellitus related to glucose, and heart attack, as well as stroke related to cholesterol...
October 16, 2022: Analytica Chimica Acta
https://read.qxmd.com/read/36153454/-electroacupuncture-preconditioning-alleviates-renal-injury-and-oxidative-stress-through-sirt3-mnsod-pathway-in-type-2-diabetic-rats
#2
JOURNAL ARTICLE
Kun-Xiu Wang, Feng-Xia Liang, Song Wu, Song Chen, Zhi-Hui Luo, Yong-Li Han, Jia Chen, Bei Chen, Zi-Qin Chen, Yan-Lin Zhang, Ting Zhou, Xiao-Lei Gu
OBJECTIVE: To explore the protective effect and molecular mechanism of electroacupuncture (EA) preconditioning on renal injury in type 2 diabetic rats. METHODS: Fifty male Wistar rats were randomly divided into control, model, EA, EA+inhibitor, and inhibitor groups, with 10 rats in each group. Diabetes model was established by high fat and high glucose diet and intraperitoneal injection of streptozotocin (40 mg/kg). EA (2 Hz, 1 mA) preconditioning was applied to "Guanyuan" (CV4), "Zhongwan" (CV12), bilateral "Zusanli" (ST36) and "Fenglong" (ST40) for 15 min, once every other day for 8 weeks...
September 25, 2022: Zhen Ci Yan Jiu, Acupuncture Research
https://read.qxmd.com/read/36039095/holistic-multi-class-classification-grading-of-diabetic-foot-ulcerations-from-plantar-thermal-images-using-deep-learning
#3
JOURNAL ARTICLE
Shishir Muralidhara, Adriano Lucieri, Andreas Dengel, Sheraz Ahmed
PURPOSE: Diabetic foot is a common complication associated with diabetes mellitus (DM) leading to ulcerations in the feet. Due to diabetic neuropathy, most patients have reduced sensitivity to pain. As a result, minor injuries go unnoticed and progress into ulcers. The timely detection of potential ulceration points and intervention is crucial in preventing amputation. Changes in plantar temperature are one of the early signs of ulceration. Previous studies have focused on either binary classification or grading of DM severity, but neglect the holistic consideration of the problem...
December 2022: Health Information Science and Systems
https://read.qxmd.com/read/35443379/evaluation-of-adiponectin-levels-in-patients-with-diabetes-mellitus
#4
JOURNAL ARTICLE
Pooja Ag, Chaitanya Kumar S
OBJECTIVES: To measure Plasma Adiponectin concentrations in patients with Type 2 Diabetes mellitus and compare with Plasma Adiponectin levels in Non Diabetic healthy controls. MATERIAL AND METHODS: Study includes 60 Diabetic cases and 60 age and sex matched Non-Diabetic healthy controls. OBSERVATION AND RESULTS: Adiponectin levels were significantly lower in 60 Diabetic patients (mean adiponectin levels=3.32±1.57 p<0.05) when compared to Non Diabetic controls (mean=10...
April 2022: Journal of the Association of Physicians of India
https://read.qxmd.com/read/35043378/bupivacaine-induces-ros-dependent-autophagic-damage-in-drg-neurons-via-tug1-mtor-in-a-high-glucose-environment
#5
JOURNAL ARTICLE
Luying Lai, Yongwei Wang, Shenghui Peng, Wenjing Guo, Guanshan Wei, Le Li, Zhengyuan Xia, Fengxian Li, Shiyuan Xu
Bupivacaine (BP) is a commonly clinically used local anesthetic (LA). Current studies suggest that neurological complications are increased in diabetic patients after LA application, but the molecular mechanism is poorly understood. LA-induced autophagy and neuronal injury have been reported. We hypothesized that a high-glucose environment aggravates BP-induced autophagic damage. Mouse dorsal root ganglion (DRG) neurons were treated with BP in a high-glucose environment, and the results showed that reactive oxygen species (ROS) levels increased, autophagy was activated, autophagy flux was blocked, and cell viability decreased...
February 2022: Neurotoxicity Research
https://read.qxmd.com/read/33915345/empagliflozin-induced-euglycemic-diabetic-ketoacidosis-in-a-patient-undergoing-coronary-artery-bypass-graft-despite-discontinuation-of-the-drug-48-hours-prior-to-the-surgery
#6
Mohammad Shafi Kuchay, Sunil Kumar Mishra, Yatin Mehta
No abstract text is available yet for this article.
May 2021: Diabetes & Metabolic Syndrome
https://read.qxmd.com/read/33209816/early-detection-of-renal-disease-among-truck-drivers-through-organized-screening
#7
JOURNAL ARTICLE
Rama Ravi, Georgi Abraham, Rajalakshmi Ravi, Milly Mathews, Rajeevalochana Partasarathy
BACKGROUND: Trucking industry is the backbone of trade and economy and in India, truck drivers are occupationally faced with various challenges. Several risk factors including stress and abnormal lifestyle predisposes this group to non-communicable disease and chronic kidney disease (CKD) is one of the major threats. This study was carried out to evaluate the prevalence and risk factors of chronic kidney disease. METHODS: The present cross-sectional study was carried out as a population-based screening programme among 3,200 truck drivers in Tamil Nadu for a period of 1 year in 2018...
September 2020: Journal of Family Medicine and Primary Care
https://read.qxmd.com/read/32143184/compounds-that-modulate-ampk-activity-and-hepatic-steatosis-impact-the-biosynthesis-of-micrornas-required-to-maintain-lipid-homeostasis-in-hepatocytes
#8
JOURNAL ARTICLE
Jèssica Latorre, Francisco J Ortega, Laura Liñares-Pose, José M Moreno-Navarrete, Aina Lluch, Ferran Comas, Núria Oliveras-Cañellas, Wifredo Ricart, Marcus Höring, You Zhou, Gerhard Liebisch, P A Nidhina Haridas, Vesa M Olkkonen, Miguel López, José M Fernández-Real
BACKGROUND: While the impact of metformin in hepatocytes leads to fatty acid (FA) oxidation and decreased lipogenesis, hepatic microRNAs (miRNAs) have been associated with fat overload and impaired metabolism, contributing to the pathogenesis of non-alcoholic fatty liver disease (NAFLD). METHODS: We investigated the expression of hundreds of miRNAs in primary hepatocytes challenged by compounds modulating steatosis, palmitic acid and compound C (as inducers), and metformin (as an inhibitor)...
March 2020: EBioMedicine
https://read.qxmd.com/read/31853119/out-of-pocket-payment-for-diabetes-mellitus-in-a-public-hospital-of-karachi
#9
JOURNAL ARTICLE
Syed Muhammad Ibrahim Hashmi, Shiraz Shaikh, Sana Tanzil, Lubna Baig, Nimra Shahid, Amna Abdullah
OBJECTIVE: To estimate the out-of-pocket payment on routine management of type 2 diabetes in patients attending a public-sector facility. METHODS: The cross-sectional study was conducted from December 2016 to May 2017 at Jinnah Postgraduate Medical Centre, Karachi, and comprised of persons with type 2 diabeties. A pretested questionnaire was administered to collect data from the patients. Comparisons of average out-of-pocket expenditure were done across different groups on the basis of gender, education, monthly income and duration of disease...
December 2019: JPMA. the Journal of the Pakistan Medical Association
https://read.qxmd.com/read/30679404/-prevention-and-treatment-for-vascular-calcification-in-patients-with-diabetes-mellitus
#10
JOURNAL ARTICLE
Masahiro Yamamoto
It has been known that diabetes mellitus is known to have a high risk of cardiovascular diseases as well as osteoporosis. Prevention and treatment of vascular calcification in patients with diabeties mellitus by anti-osteoporosis agents is prospected bcause similar molecular mechanisms in bone tissue were found in calcified lesion in blood vessels. However, the anti-vascular calcification effect has not always been observed in clinical practice in contrast to basic research and animal experiments. More optimized clinical research desined for prevention of vascular calcification as primary outcome, such as applying elaborated method for detemination of calcified lesion, is needed...
2019: Clinical Calcium
https://read.qxmd.com/read/30158791/evaluation-of-relationship-between-dental-caries-diabetes-mellitus-and-oral-microbiota-in-diabetics
#11
JOURNAL ARTICLE
Bhagyashri Ramachandra Latti, Jitendra V Kalburge, Sanjeev Bhimashankar Birajdar, Ramachandra Girimallappa Latti
BACKGROUND: Diabetes mellitus is a metabolic disease leading to abnormal fat, carbohydrate and protein metabolism. Reduced salivary flow rate caused by hyperglycemia is characteristic mainly for periods of poor metabolic control of diabetes, thereby facilitating the growth of aciduric bacteria and caries-lesion development. The objective of our study was to evaluate the effects of diabetes mellitus on dental caries micro-organisms responsible for caries. MATERIALS AND METHODS: This study was carried out on 60 subjects consisting of 2 groups...
May 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
https://read.qxmd.com/read/28063957/initial-development-and-validation-of-a-patient-reported-symptom-survey-for-small-fiber-polyneuropathy
#12
JOURNAL ARTICLE
Roi Treister, Mette Lodahl, Magdalena Lang, Shelley S Tworoger, Shlomo Sawilowsky, Anne Louise Oaklander
Small-fiber polyneuropathy (SFPN) affects unmyelinated and thinly myelinated peripheral axons. Several questionnaires have been developed to assess polyneuropathy from diabetes or chemotherapy, but none for SFPN from other or unknown causes. A comprehensive survey could help clinicians diagnose and assess treatment responses, define prevalence natural history and cures, and identify research subjects. Thus, we developed the 1-page Small-Fiber Symptom Survey, using input from patients and 21 medical/scientific experts...
May 2017: Journal of Pain
https://read.qxmd.com/read/28017292/bullosis-diabeticorum-in-a-young-child-case-report-of-a-very-rare-entity-and-a-literature-review
#13
REVIEW
Anca Chiriac, Irina Costache, Cristian Podoleanu, Adrian Naznean, Simona Stolnicu
Bullosis diabeticorum (BD), or diabetic bulla, is 1 of the cutaneous manifestations of diabetes mellitus, reported in 0.5% of people with diabeties in the United States, mostly in adult men who have had long-lasting and uncontrolled diabetes associated with diabetic peripheral neuropathy. However, BD in young children is a mostly unrecognized entity. We present a case of BD in a 3-year-old girl with type 1 diabetes mellitus who had been treated with insulin for 7 months prior to hospitalization. Dermatologic examination revealed a large, tense bulla filled with clear fluid and not associated with pain or pruritus, localized on the lateral margin of the right hand...
April 2017: Canadian Journal of Diabetes
https://read.qxmd.com/read/25714197/assessment-of-myocardial-ischemia-in-obese-individuals-undergoing-physical-stress-echocardiography-pse
#14
JOURNAL ARTICLE
Mara Graziele Maciel Silveira, Antônio Carlos Sobral Sousa, Marcos Antônio Almeida Santos, Irlaneide da Silva Tavares, Stephanie Macedo Andrade, Luiza Dantas Melo, Loren Suyane Oliveira de Andrade, Emmanuel Lima Almeida Santos, Joselina Luzia Menezes Oliveira
BACKGROUND: Physical stress echocardiography is an established methodology for diagnosis and risk stratification of coronary artery disease in patients with physical capacity. In obese (body mass index ≥ 30 kg/m2) the usefulness of pharmacological stress echocardiography has been demonstrated; however, has not been reported the use of physical stress echocardiography in this growing population group. OBJECTIVE: To assess the frequency of myocardial ischemia in obese and non-obese patients undergoing physical stress echocardiography and compare their clinical and echocardiographic differences...
May 2015: Arquivos Brasileiros de Cardiologia
https://read.qxmd.com/read/24761497/distribution-of-certain-risk-factors-among-dyslipidaemic-patients-morbid-with-first-episode-coronary-heart-disease
#15
JOURNAL ARTICLE
R K Vinod, M Shashikala, K P Suresh
The objectives of the study were to determine dyslipidaemia prevalence in first episode coronary heart disease cases and to determine the pattern of distribution of risk factors in this temporal relationship. This hospital based retrospective cohort study was conducted at Basaveshwara Teaching Hospital, Gulbarga, during January 2012. Data for the 3 year period (January 2005-December 2007) were collected from the case sheets of cardiac care unit admissions. Out of the 1,373 admissions to the cardiac care unit over the 36 months period, 462 case sheets were examined as these were the ones with first episode coronary heart disease aetiology...
June 2013: Journal of the Indian Medical Association
https://read.qxmd.com/read/24393733/acute-effects-of-five-ghanaian-carbohydrate-diets-on-serum-glucose-triglyceride-and-insulin-in-niddm
#16
JOURNAL ARTICLE
I K Quaye, L A Brakohiakpa, G A Amoah, N Ayi-Ankrah, Y Kido
Glycemic indices have been used to predict useful carbohydrate sources of food for patients with non-insulin-dependent diabeties mellitus (NIDDM) on dietary management programs. The present study has revealed that glycemic indices alone are not adequate predictors of useful carbohydrate meal sources. We observed for the first time that glycemic indexes inversely correlate with triglyceride indices. In our test mixed meals varying in five Ghanaian carbohydrate food types for nine non-insulin dependent diabetics, the correlation between glycemic and triglyceride indices was (r = -0...
March 1999: Asia Pacific Journal of Clinical Nutrition
https://read.qxmd.com/read/24393637/food-intake-patterns-in-urban-beijing-chinese
#17
JOURNAL ARTICLE
P Fu, H Zhang, S M Siew, S Q Wang, A Xue, B H Hsu-Hage, M L Wahlqvist, Y F Wang, X X Li
This study investigated the food consumption patterns of 430 Beijing Chinese adults and assessed the impact on these patterns of the following socio-demographic characteristics: gender, age, educational achievement, and gross household income. Food intake by category, food variety and meal patterns were assessed using a 156-item food frequency questionnaire. It was found that gender and age were the most important factors to influence food consumption patterns. Men consumed more wheat products, red meat and tea, whereas women consumed more vegetables, fruit, nuts, fish, eggs and milk...
June 1998: Asia Pacific Journal of Clinical Nutrition
https://read.qxmd.com/read/23724283/can-diabetes-i-and-early-blindness-be-prevented-using-a-tylenol-combination-which-inhibits-oxidative-and-nitrosative-stress
#18
JOURNAL ARTICLE
Knox Van Dyke, Erica Ghareeb, Robert Hoeldtke, Mark Van Dyke, Chris Van Dyke, David Van Thiel
Since oxidative/nitrosative stress cause diabetes, can we prevent this chemistry generating the disease? Streptozotocin causes diabetes by entering the pancreatic beta cell generating excessive nitric oxide which reacts with oxygen creating a toxin possibly peroxynitrite, dinitrogen trioxide, dinitrogen tetraoxide and so forth. The toxic compounds damage the DNA causing beta cell death. This prevents insulin synthesis, storage and release. By using antioxidant substances that destroy the nitric-oxide-based toxins (e...
2011: ISRN Toxicology
https://read.qxmd.com/read/23716866/vulnerability-of-gastric-mucosa-in-diabetic-rats-its-pathogenesis-and-amelioration-by-cuminum-cyminum
#19
JOURNAL ARTICLE
N Vador, Aarti G Jagtap, Archana Damle
Various studies have indicated that peptic ulcers occurring during the course of diabetic state are more severe and often associated with complications such as gastrointestinal bleeding. This study is the first attempt to understand the pathogenesis of gastric ulcers occurring during the diabetic state considering alternate biochemical pathways using suitable markers and its amelioration by Cuminum cyminum. In this study, diabetic rats showed a progressive increase in the stomach advanced glycated end products formation, gastric mucosal tumour necrosis factor-α and Thiobarbituric acid reactive substances levels as compared to normal control (nondiabetic) rats...
September 2012: Indian Journal of Pharmaceutical Sciences
https://read.qxmd.com/read/23699007/is-the-apnea-link-a-reliable-tool-in-the-diagnosis-of-obstructive-sleep-apnea-osa
#20
Ayham Deeb, Salim Abou Jaoude, Mary Ann Winkle
SESSION TYPE: Sleep PostersPRESENTED ON: Wednesday, October 24, 2012 at 01:30 PM - 02:30 PMPURPOSE: To find out if the apnea link test (AL) is a reliable device for diagnosis or exclusion of OSA. To assess the correlation between AL and an overnight in-laboratory polysomnogram (PSG) performed at an accredited sleep laboratory, and to select a diagnostic apnea hypopnea index (AHI) cut off point on the AL that would reliably diagnose OSA.METHODS: We designed a prospective study that included patients who were hospitalized with a variety of conditions (Congestive heart failure, COPD, asthma exacerbation, diabeties and sepsis) between July 2009 and July 2011, who had a high clinical suspicion for OSA, and an AL performed during their hospitalization...
October 1, 2012: Chest
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