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https://www.readbyqxmd.com/read/29469756/essential-telangiectasia-in-an-infant-a-diagnosis-to-be-considered
#1
Pablo Fernández-Crehuet, Ricardo Ruiz-Villaverde
Essential generalized telangiectasia as the result of postcapillary venule dilatation, is characterized by the sudden development of generalized telangiectasias, sometimes involving the conjunctiva. A few pediatric cases have been reported. The main condition in the differential diagnosis includes syndromes with telangiectasia such as hereditary hemorrhagic telangiectasia of Rendu-Osler, unilateral nevoid telangiectasia, and neonatal lupus erythematous. We present an 11-month-old boy that presented because of telangiectasia located on the face and neck...
August 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29461128/ocular-complications-after-cosmetic-periocular-diode-laser-application-to-the-eyelids
#2
Duygu Gulmez Sevim, Ayse Ozturk Oner, Metin Unlu, Galip Ertugrul Mirza
A 25-year-old woman underwent diode laser application on the both upper eyelids in the dermatology department of a private hospital to obtain a cosmetic healing of the reddish look on her eyelids without any protective lenses. The patient experienced severe uveitis, atonic pupils, raised intraocular pressure, and increased sensitivity to light in her eyes on the following day of the procedure. Topical steroids and pressure-lowering agents were able to treat the acute uveitis and glaucoma, unfortunately the patient suffered from irreversible atonic and atrophic pupils and photosensitivity...
February 20, 2018: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/29436720/an-expanded-study-of-long-pulsed-1064-nm-nd-yag-laser-treatment-of-basal-cell-carcinoma
#3
Arisa E Ortiz, R Rox Anderson, Catherine DiGiorgio, Shang I Brian Jiang, Faiza Shafiq, Mathew M Avram
BACKGROUND AND OBJECTIVE: Basal cell carcinoma (BCC) is an indolent form of skin cancer that is rarely life threatening, but can cause significant cosmetic and functional morbidity. Surgical treatments often result in disfiguring scars, while topical therapies frequently result in recurrence. The need for a more effective nonsurgical alternative has led to the investigation of laser treatment of BCC. We have previously conducted a pilot study which showed 100% histologic clearance at high fluences...
February 13, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29434427/picosecond-laser-treatment-for-tattoos-and-benign-cutaneous-pigmented-lesions-secondary-publication
#4
REVIEW
Kenichiro Kasai
Background and aims: The selective removal of tattoos and benign cutaneous pigmented lesions with laser energy evolved rapidly with the development of the nanosecond-domain Q-switched laser (ns-laser). Recently, however, a series of picosecond-domain lasers (ps-lasers) with pulsewidths less than 1 ns has become commercially available, enabling more efficient and faster removal of pigmented lesions in the field of dermatologic laser surgery. Rationale behind the ps-laser: The efficacy of the ns-laser depended on the theory of selective photothermolysis, whereby an extremely short pulse width was delivered less than the thermal relaxation time (TRT) of a target...
December 31, 2017: Laser Therapy
https://www.readbyqxmd.com/read/29431372/pigmentation-disorders-diagnosis-and-management
#5
Scott Plensdorf, Maria Livieratos, Nabil Dada
Pigmentation disorders are commonly diagnosed, evaluated, and treated in primary care practices. Typical hyperpigmentation disorders include postinflammatory hyperpigmentation, melasma, solar lentigines, ephelides (freckles), and café au lait macules. These conditions are generally benign but can be distressing to patients. Appropriate dermatologic history, skin examination, and skin biopsy, when appropriate, can help exclude melanoma and its precursors. In addition to addressing the underlying condition, hyperpigmentation is treated with topical agents, chemical peels, cryotherapy, light or laser therapy, or a combination of these methods...
December 15, 2017: American Family Physician
https://www.readbyqxmd.com/read/29419905/once-weekly-targeted-excimer-light-produced-modest-re-pigmentation-of-vitiligo-over-a-20-week-period
#6
S Ayob, S E Cockayne, D J Gawkrodger
Vitiligo is an acquired disorder of depigmentation resulting from the loss of functional epidermal melanocytes. It has a worldwide prevalence of 0.5-2%. Vitiligo can have a major negative impact on patients' quality of life.Current treatments include topical corticosteroids and immunomodulators, systemic immunosuppressants, cosmetic camouflage, ultraviolet radiation and surgical procedures, e.g. punch grafting. Recently, targeted phototherapy using the 308-nm xenon-chloride (XeCl) monochromatic excimer light (MEL) delivered by a laser or a lamp emitting non-coherent monochromatic light has been used...
February 8, 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29415242/a-single-blind-study-evaluating-the-efficacy-of-gold-nanoparticle-photothermal-assisted-liposuction-in-an-ex-vivo-human-tissue-model
#7
Wangzhong Sheng, William J Seare, Barry DiBernardo, Ali H Alhasan, Esther Cory, Paul Chasan, Robert L Sah, Khalid M Almutairi, Adah Almutairi
Background: Liposuction is one of the most performed cosmetic surgery procedures. In a previously reported study, gold-nanoparticle (GNP) laser-assisted liposuction (NanoLipo) was shown to improve procedure parameters and outcomes in a porcine model. Objective: An ex vivo human liposuction model was developed to assess the ease, efficacy, and outcomes of NanoLipo, and to further explore its mechanism of action in facilitating liposuction. Methods: NanoLipo was compared to a Control without GNPs in sets of fresh, non-perfused, anatomically-symmetric, matched tissue specimens from 12 patients...
February 3, 2018: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29414736/a-novel-cosmetic-and-clinically-practicable-laser-immunotherapy-for-facial-verruca-plana-intense-pulsed-light-combined-with-bcg-psn
#8
Fuhe Zhang, Lei Shi, Pei Liu, Linglin Zhang, Qianqian Wu, Bo Wang, Guolong Zhang, Peiru Wang, Feifang Zhou, Wei R Chen, Xiuli Wang
BACKGROUND: There is no alternative method to remove facial verruca plana and achieve better cosmetic effects. The present study is the first study to use intense pulsed light (IPL) as photothermal therapy (PTT) combined with intra-gluteal injection of bacillus calmette-guerin polysaccharide nucleic acid (BCG-PSN), which function as immunotherapy, contracting a new type of clinically available laser immunotherapy(LIT)for the treatment of facial verruca plana. The aim of this study was to evaluate the efficacy, cosmetic outcome, and adverse reactions of IPL combined with BCG-PSN for facial verruca plana...
February 4, 2018: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29393762/effective-use-of-nonablative-fractional-laser-on-multiple-whip-scars
#9
Santo Mercuri, Pina Brianti, Enza Cestone, Annunziata Dattola, Steven Paul Nisticò
BACKGROUND: Laser technology provides different solutions for scar treatment from the traditional ablative lasers to the more recent fractional devices. PATIENTS AND METHODS: We present the case of a young woman treated for scars induced by severe whipping since the age of 10. She received four monthly nonablative fractional 1550 nm erbium glass laser treatments. Fluence used was 20 mJ/cm2 with 1500 microthermal zones/cm2. RESULTS: Significant improvement was documented in the color and texture of the lesion at the end of treatment and at follow-up...
February 2, 2018: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/29377414/optical-clearing-agent-reduces-scattering-of-light-by-the-stratum-corneum-and-modulates-the-physical-properties-of-coenocytes-via-hydration
#10
S-H Lee, S-H Jun, J Yeom, S-G Park, C-K Lee, N-G Kang
BACKGROUND: The interaction between light and the skin determine how the skin looks to the human eye. Light can be absorbed, scattered, and reflected by different components of the skin in a variety of different ways. Here, we focus on the scattering properties of the outmost layer, the stratum corneum (SC). However, we currently have limited methods with which to distinguish the scattering of light by SC from the changes due to other components of the skin. MATERIALS AND METHODS: Dark-field images of tape-striped corneocytes were used in vitro to study the differences in light scattered by the SC and other skin components...
January 28, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29369914/a-single-center-randomized-double-blind-placebo-controlled-clinical-trial-of-the-effectiveness-of-ant1-soybean-extract-cream-on-skin-recovery-after-nd-yag-laser-treatment
#11
Meng-Chien Hsieh, Yi-Chia Wu, Shu-Hung Huang, Yur-Ren Kuo, Su-Shin Lee
Nd:YAG laser has been used extensively for its versatility in treating many common aesthetic problems, but numerous adverse effects are often complained by recipients of Nd:YAG laser. This study introduces the ANT1 soybean extract cream, which was formulated to alleviate adverse effects after laser therapy. This study explores whether ANT1 enhances the repair mechanism of the postlaser skin, decreases laser-induced complication, and shortens recovery time. The study also aims to pinpoint the ANT1 concentration that is most effective in improving the skin condition after Nd-YAG laser therapy...
January 25, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29364259/second-harmonic-generation-signals-in-rabbit-sclera-as-a-tool-for-evaluation-of-therapeutic-tissue-cross-linking-txl-for-myopia
#12
Mariya Zyablitskaya, E Laura Munteanu, Takayuki Nagasaki, David C Paik
Methods to strengthen tissue by introducing chemical bonds (non-enzymatic cross-linking) into structural proteins (fibrillar collagens) for therapy include photochemical cross-linking and tissue cross-linking (TXL) methods. Such methods for inducing mechanical tissue property changes are being employed to the cornea in corneal thinning (mechanically weakened) disorders such as keratoconus as well as the sclera in progressive myopia, where thinning and weakening of the posterior sclera occurs and likely contributes to axial elongation...
January 6, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29351725/daylight-mediated-photodynamic-therapy-with-methyl-aminolevulinate-in-actinic-keratosis-treatment
#13
Shantel D J Demay, Kunal Sharma, Sheetal Sapra, Rahul Sapra, Priya Sapra
BACKGROUND: Research has shown daylight-mediated photodynamic therapy (PDT) for the treatment of actinic keratosis (AK) to be effective, tolerable, and convenient, with excellent patient satisfaction and cosmesis. Although success has been demonstrated in areas with similar latitudes to Switzerland and Scandinavia, this treatment has not been studied in a Canadian population. OBJECTIVES: The purpose of this study is to investigate the effectiveness, safety, and patient satisfaction of daylight-mediated methyl 5-aminolevulinate (MAL)-PDT to make recommendations for its use in Canadian practice...
January 1, 2018: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/29336034/quantitative-evaluation-of-collagen-and-elastic-fibers-after-intense-pulsed-light-treatment-of-mouse-skin
#14
Luciana L Faucz, Sonia E Will, Consuelo J Rodrigues, Henrique Hesse, Angelina C Moraes, Durvanei A Maria
BACKGROUND AND OBJECTIVE: The aging of human skin includes intrinsic aging and photo-aging, which are characterized by a decrease in collagen and the deposition of abnormal elastic fibers. Intense pulsed light (IPL) sources are widely used in medicine to treat various cosmetic problems, including photo-damaged skin. Few studies have examined the microscopic changes produced by IPL. The objective of this study was to quantitatively evaluate the effects of IPL on collagen and elastic fibers in mice...
January 16, 2018: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29330276/cutaneous-mycobacterium-massiliense-infection-from-tattooing-a-common-yet-under-reported-and-persistent-epidemic-hazard-for-dermatologists
#15
Lymaries Velez, Jennifer Harb, Stephanie Anuszewski, Stanton Wesson
Tattoo popularity continues to rise, with 3 in 10 Americans bearing at least one. Among tattoo complications, non-tuberculous mycobacteria (NTM) has emerged as a global public health concern. NTM infections associated with tattooing of immunocompetent individuals have occurred as sporadic cases and community outbreaks. Water sources are considered the major pathogenic reservoirs. Tattoo-related inoculation has been linked to contamination of ink, either during the manufacturing process or during dilution of black ink using non-sterile water...
January 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29306639/skin-tissue-engineering-using-3d-bioprinting-an-evolving-research-field
#16
REVIEW
Sam P Tarassoli, Zita M Jessop, Ayesha Al-Sabah, Neng Gao, Sairan Whitaker, Shareen Doak, Iain S Whitaker
BACKGROUND: Commercially available tissue engineered skin remains elusive despite extensive research because the multi-stratified anisotropic structure is difficult to replicate in vitro using traditional tissue engineering techniques. Bioprinting, involving computer-controlled deposition of cells and scaffolds into spatially controlled patterns, is able to control not only the macro but also micro and nanoarchitecture and could offer the potential to more faithfully replicate native skin...
December 13, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29273963/transglycosylation-of-gallic-acid-by-using-leuconostoc-glucansucrase-and-its-characterization-as-a-functional-cosmetic-agent
#17
Seung-Hee Nam, Jeongjin Park, Woojin Jun, Doman Kim, Jin-A Ko, A M Abd El-Aty, Jin Young Choi, Do-Ik Kim, Kwang-Yeol Yang
Gallic acid glycoside was enzymatically synthesized by using dextransucrase and sucrose from gallic acid. After purification by butanol partitioning and preparative HPLC, gallic acid glucoside was detected at m/z 355 (C13, H16, O10, Na)+ by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. The yield of gallic acid glucoside was found to be 35.7% (114 mM) by response surface methodology using a reaction mixture of 319 mM gallic acid, 355 mM sucrose, and 930 mU/mL dextransucrase...
December 22, 2017: AMB Express
https://www.readbyqxmd.com/read/29232991/mass-spectrometry-imaging-of-illicit-drugs-in-latent-fingerprints-by-matrix-free-and-matrix-assisted-desorption-ionization-techniques
#18
Anton Skriba, Vladimir Havlicek
Compared with classical matrix-assisted laser-desorption ionization mass spectrometry (MALDI), the matrix free-based strategies generate a cleaner background, without significant noise or interference coming from an applied matrix, which is beneficial for the analysis of small molecules, such as drugs of abuse. In this work, we probed the detection efficiency of methamphetamine, heroin and cocaine in nanostructure-assisted laser desorption-ionization (NALDI) and desorption electrospray ionization and compared the sensitivity of these two matrix-free tools with a standard MALDI mass spectrometry experiment...
January 1, 2017: European Journal of Mass Spectrometry
https://www.readbyqxmd.com/read/29223636/revisiting-lip-shave-a-solution-for-disorders-of-the-vermilion-border
#19
A Sayan, S Wijesinghe, S Paraneetharan, V Ilankovan
Actinic keratosis, leukoplakia, carcinoma in situ, and superficially invasive carcinomas of the lower lip are caused mainly by the cumulative effects of exposure of the vermilion of the lower lip to ultraviolet radiation. Current treatments all have limitations: cryosurgery or electrosurgery is suitable to treat only focal lesions; topical chemotherapy, which is an option for diffuse actinic damage, yields unreliable results; and laser treatment fails to rejuvenate the vermilion. However, "lip shave", which involves full-thickness excision of the damaged vermilion and reconstruction with an advancement labial mucosal flap, will produce a fresh mucosal lining to the vermilion border...
December 6, 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29196283/ringed-telangiectasias-an-unusual-presentation-of-telangiectasia-macularis-eruptiva-perstans
#20
Laila Siddique, Hadjh Ahrns, Elizabeth Seiverling
Telangiectasia macularis eruptiva perstans (TMEP) is a rare form of cutaneous mastocytosis. While most cutaneous mastocytoses occur in children and are asymptomatic, TMEP occurs predominantly in adults and is associated with systemic manifestations, requiring medical management. TMEP is typically characterised by scattered red-brown macules on the trunk and extremities, but must be differentiated from other telangiectatic conditions such as scleroderma, hereditary haemorrhagic telangiectasia and telangiectasias secondary to cirrhosis...
November 30, 2017: BMJ Case Reports
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