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https://www.readbyqxmd.com/read/27918003/combination-therapy-in-skin-of-color-including-injectables-laser-and-light-devices
#1
Lark Guss, Joanna G Bolton, Sabrina Guillen Fabi
With the rapid increase in patients seeking cosmetic treatments, the variation in responses of lightly pigmented skin versus darkly pigmented skin has become increasingly apparent. Despite extensive treatment options in patients with skin of color, there is a paucity of well-designed studies performed on this patient population. The lack of research is concerning, as it is well documented that patients with darker skin types are at an increased risk of adverse events when treated with many of the available modalities used in cosmetic procedures...
December 2016: Seminars in Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27911476/nd-yag-and-pulsed-dye-laser-therapy-in-infantile-hemangiomas-a-retrospective-analysis-of-271-treated-hemangiomas-in-149-children
#2
F Hartmann, A Lockmann, L-L Grönemeyer, H A Haenssle, M Zutt, H von Fintel, I Kühnle, M P Schön, K-M Thoms
BACKGROUND: Infantile hemangiomas (IH) are common benign tumors in infancy. Most IH resolve spontaneously, but some require treatment due to ulceration, functional impairment or cosmetic disfiguration. While systemic propranolol is effective in many cases, laser therapy may be a safe topical alternative. OBJECTIVE: To assess the efficacy of combined Nd:YAG/pulsed dye laser (PDL) or PDL alone for therapy of IH. PATIENTS AND METHODS: 271 IH in 149 infants were treated with combined Nd:YAG/PDL or PDL alone...
December 2, 2016: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/27878794/varicosities-of-the-lower-extremity-new-approaches-cosmetic-or-therapeutic-needs
#3
Luca Spinedi, Heiko Uthoff, Sasan Partovi, Daniel Staub
Varicose veins of the lower extremity (VVLE) are a frequently encountered vascular disorder in the general population. The general view that VVLE are a non-serious disease with primarily aesthetic impact is a common misconception, as the disease can have a significant negative impact on generic and disease-specific quality of life. Further, VVLE may be associated with potentially threatening clinical conditions, such as chronic venous ulceration, venous thromboembolism and haemorrhage from ruptured varicose veins...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/27873347/infantile-hemangioma-with-minimal-or-arrested-growth-further-observations-on-clinical-and-histopathologic-findings-of-this-unique-but-underrecognized-entity
#4
Ellen Hui Ma, Susan J Robertson, Chung W Chow, Philip S Bekhor
BACKGROUND: Infantile hemangioma (IH) with minimal or arrested growth (IH-MAG) is becoming increasingly recognized in the literature. It is important to be aware of their existence, because the correct diagnosis is essential for prognostication and treatment and, in the case of facial segmental lesions, the direction of further investigations if PHACE (posterior fossa abnormalities and other structural brain abnormalities; hemangioma(s) of the cervical facial region; arterial cerebrovascular anomalies; cardiac defects, aortic coarctation, and other aortic abnormalities; eye anomalies) syndrome or Sturge-Weber syndrome is suspected...
November 22, 2016: Pediatric Dermatology
https://www.readbyqxmd.com/read/27862066/fractional-co2-laser-treatment-of-caesarean-section-scars-a-randomized-controlled-split-scar-trial-with-long-term-follow-up-assessment
#5
Katrine E Karmisholt, Elisabeth H Taudorf, Camilla B Wulff, Emily Wenande, Peter A Philipsen, Merete Haedersdal
BACKGROUND AND OBJECTIVES: Caesarean section (c-section) scars can be pose functional and cosmetic challenges and ablative fractional laser (AFXL) treatment may offer benefit to patients. We evaluated textural and color changes over time in AFXL-treated versus untreated control scars. MATERIALS AND METHODS: A randomized, controlled, intra-individual split-scar trial with three sessions of AFXL-treatments for mature c-section scars. Settings of AFXL were adjusted to each individual scar...
November 8, 2016: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/27856773/real-world-efficacy-of-1064-nm-nd-yag-laser-for-the-treatment-of-onychomycosis
#6
REVIEW
Jason K Rivers, Brianne J Vestvik, Jonathan Berkowitz
BACKGROUND: Onychomycosis is a cosmetic and, at times, medical concern; therefore, effective and safe alternatives to treatment are needed. OBJECTIVE: To determine the efficacy of a 1064-nm Nd:YAG laser for the treatment of onychomycosis in a real-world setting. METHODS: A single-centre retrospective chart review was conducted between 2012 and 2013. One hundred consecutive patients with a culture- and/or potassium hydroxide-confirmed diagnosis of onychomycosis were treated at least twice...
November 16, 2016: Journal of Cutaneous Medicine and Surgery
https://www.readbyqxmd.com/read/27846771/an-8-year-population-description-from-a-national-treatment-centre-on-lymphatic-malformations
#7
Jill Josefine Eliasson, Inanna Weiss, Hans Erik Høgevold, Nina Oliver, Rune Andersen, Kirsti Try, Kim Alexander Tønseth
INTRODUCTION: Lymphatic malformations are rare developmental non-malignant abnormalities that present as masses consisting of abnormal growth of fluid filled channels or spaces in the skin or deep tissue that result in abnormalities of lymphatic flow. They may cause symptoms like pain, recurrent lymphorrea, abnormal bone growth, and disturbance of bodily functions. They may also be a cosmetic problem. The study aims to describe the population with lymphatic malformations (LM) treated at a national referral centre...
November 16, 2016: Journal of Plastic Surgery and Hand Surgery
https://www.readbyqxmd.com/read/27842856/hyaluronan-polymeric-micelles-for-topical-drug-delivery
#8
Daniela Šmejkalová, Tomáš Muthný, Kristina Nešporová, Martina Hermannová, Eva Achbergerová, Gloria Huerta-Angeles, Marek Svoboda, Martin Čepa, Veronika Machalová, Dominika Luptáková, Vladimír Velebný
Nanosized materials offer promising strategy for topical drug delivery due to their enhancing effect on drug percutaneous transport across the stratum corneum barrier. In this work, polymeric micelles made from hydrophobized hyaluronic acid (HA) were probed for skin delivery. Compared to non-polymeric micelle solutions containing similar drug amount, in vitro skin penetration analysis indicated 3 times larger deposition of drug in the epidermis and 6 times larger drug deposition in the dermis after 5h of topical treatment in Franz diffusion cells...
January 20, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27806525/clinical-effectiveness-of-gingival-depigmentation-using-conventional-surgical-scrapping-and-diode-laser-technique-a-quasi-experimental-study
#9
Raghavendra Reddy Nagati, M Ragul, Nabeeh A Al-Qahtani, K S Ravi, S Tikare, Mohan Kumar Pasupuleti
Excessive gingival pigmentation is a major aesthetic concern in modern society, though it is not a medical problem they consider it as a negative attribute. Patients with gingival hyperpigmentation usually complain and request cosmetic therapy, particularly if the pigmentation is visible during speaking and smiling. Various depigmentation methods, including burr abrasion, cryosurgery, electro-surgery, split thickness flap excision and surgical scraping techniques have been used with varying degrees of success...
August 1, 2016: Global Journal of Health Science
https://www.readbyqxmd.com/read/27802065/a-review-on-laser-and-light-based-therapies-for-alopecia-areata
#10
Stephanie Mlacker, Adam Souhail Aldahan, Brian James Simmons, Vidhi Shah, Colin Andrew McNamara, Sahal Samarkandy, Keyvan Nouri
Alopecia areata is a form of non-scarring alopecia that results from a hyperactive immune response of T cells against hair follicles. Many patients with visible hair loss experience psychological and emotional distress, as a result of their cosmetic disfigurement, and frequently seek treatment. However, existing treatment methods, such as corticosteroids, topical irritants, sensitizing agents, immunosuppressants, and psoralen plus ultraviolet light A may result in various adverse effects and often lack efficacy...
November 1, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27766329/inertial-focusing-of-ellipsoidal-euglena-gracilis-cells-in-a-stepped-microchannel
#11
M Li, H E Muñoz, A Schmidt, B Guo, C Lei, K Goda, D Di Carlo
Euglena gracilis (E. gracilis) has recently been attracting attention as a potential renewable source for the production of biofuels, livestock feed, cosmetics, and dietary supplements. Research has focused on strain isolation, productivity improvement, nutrient and resource allocation, and co-product production, key steps that ultimately determine the economic viability and compatibility of the biomass produced. To achieve these characteristics, approaches to select E. gracilis mutants with desirable properties, such as high wax ester content, high growth rate, and high environmental tolerance for biodiesel and biomass production, are needed...
October 21, 2016: Lab on a Chip
https://www.readbyqxmd.com/read/27762652/polydeoxyribonucleotide-improves-wound-healing-of-fractional-laser-resurfacing-in-rat-model
#12
Mi Yu, Jun Young Lee
BACKGROUND: Polydeoxyribonucleotide (PDRN) is an active compound that can promote wound healing. PDRN stimulates wound healing by enhancing angiogenesis and increasing fibroblast growth rates. Laser skin resurfacing is a popular cosmetic procedure for skin rejuvenation. Despite excellent improvement of photo-damaged skin and acne scarring, it is accompanied with drawbacks, such as prolonged erythema and crusting. OBJECTIVE: This study was designed to assess the effect of PDRN on wounds induced by fractional laser resurfacing...
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27761089/evaluation-of-carbon-dioxide-laser-in-the-treatment-of-epidermal-nevi
#13
Yasmeen Jabeen Bhat, Iffat Hassan, Peerzada Sajad, Atiya Yaseen, Syed Mubashir, Saniya Akhter, Roohi Wani
BACKGROUND: Epidermal naevi are benign hamartomatous growths of the skin which are generally asymptomatic with a benign course but are cosmetically disagreeable. Topical treatments such as steroids, calcipotriol, 5 fluorouracil, podophyllin, retinoids and cryotherapy are ineffective and surgical excision results in scar formation. Therapy is often challenging. AIM OF THE STUDY: To study the response of carbon dioxide (CO2) laser in the management of epidermal naevi...
July 2016: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/27759861/dehydrated-allogenic-human-amniotic-membrane-graft-for-conjunctival-surface-reconstruction-following-removal-of-exposed-scleral-buckle
#14
Dilraj S Grewal, Tamer H Mahmoud
A 54-year-old male developed symptomatic scleral buckle exposure 16 years after placement and presented with large conjunctival defects with fibrosed edges. Following surgical removal of the buckle elements, primary conjunctival closure could not be achieved due to significant wound tension despite undermining the conjunctival edges to mobilize the conjunctiva. A dehydrated amniotic membrane graft (Ambio5; IOP Ophthalmics, Costa Mesa, CA) was placed on the scleral bed and secured in place with fibrin sealant (TISSEEL; Baxter International, Westlake Village, CA)...
October 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/27757332/the-northwestern-abdominoplasty-scar-model-a-novel-human-model-for-scar-research-and-therapeutics
#15
Steven T Lanier, Jing Liu, Claudia Chavez-Munoz, Thomas A Mustoe, Robert D Galiano
There is a growing interest in the development and evaluation of therapeutic agents that improve the cosmetic appearance of scars. Existing nonhuman animal models to study scarring, while valuable, have well-acknowledged limitations, as it is accepted that the biology of human scarring differs significantly from scarring in other species. Moreover, human clinical trials of scarring require large numbers of subjects to achieve statistical power and are plagued by inherent intersubject variability because of the complex nature of wound healing in human beings...
September 2016: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/27746633/kojic-acid-peptide-a-new-compound-with-anti-tyrosinase-potential
#16
Birendra Kumar Singh, Seok Hoon Park, Hyang-Bok Lee, Young-Aae Goo, Hyoung Shik Kim, Seung Hee Cho, Jeong Hun Lee, Ghe Whan Ahn, Jin Pyo Kim, Su Myoung Kang, Eun-Ki Kim
BACKGROUND: Kojic acid was used for decades in the cosmetic industry as an antimelanogenic agent. However, there are two major drawbacks of Kojic acid, one is cytotoxicity and second are instability on storage. These limitations led the scientist to synthesize the active Kojic acid peptides. OBJECTIVE: In the present study, we synthesize and investigate the effect of five Kojic acid peptides to overcome the limitation of Kojic acid. METHODS: The peptide was analyzed and purified by high-performance liquid chromatography and matrix-assisted laser desorption ionization time of flight mass spectroscopy...
October 2016: Annals of Dermatology
https://www.readbyqxmd.com/read/27727108/problems-and-complications-of-full-face-carbon-dioxide-laser-resurfacing-for-pathological-lesions-of-the-skin
#17
Andrew M Read-Fuller, David M Yates, David D Vu, John E Hoopman, Richard A Finn
OBJECTIVE: Facial resurfacing with a CO2 laser has been used for treatment of pathologic lesions and for cosmetic purposes. Postoperative complications and problems after laser resurfacing include infections, acneiform lesions, and pigment changes. This retrospective study describes the most common problems and complications in 105 patients and assesses postoperative pain in 38 patients. STUDY DESIGN: All patients received CO2 laser resurfacing for treatment of malignant/premalignant lesions and had postoperative follow-up to assess problems and complications...
August 23, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/27722955/laser-tattoo-removal-an-update
#18
Lina I Naga, Tina S Alster
Tattoo art has been around for thousands of years in every culture and is currently flourishing in all age groups, social classes, and occupations. Despite the rising popularity of tattoos, demand for their removal has also increased. While various treatments, including surgical excision, dermabrasion, and chemical destruction have historically been applied, over the past 2 decades, lasers have revolutionized the way tattoos are treated and have become the gold standard of treatment. To achieve optimal cosmetic outcome of treatment, lasers emitting high energies and short pulses are required to adequately destroy tattoo ink...
October 8, 2016: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/27702539/monitoring-the-architecture-of-anionic-%C3%AE%C2%BA-carrageenan-cationic-glycine-betaine-amide-surfactant-assemblies-by-dilution-a-multiscale-approach
#19
C Gaillard, Y Wang, R Covis, T Vives, Maud Benoît, T Benvegnu
The interaction between glycine betaine-based cationic surfactant and algal polysaccharide κ-carrageenan was studied by investigating the dilution effect of the surfactant/polymer assemblies driven by electrostatic interactions. Two aqueous solutions of cationic surfactant and κ-carrageenan at two molar ratios (3.5 and 0.8) diluted with factors of 5 and 10 times, were tested by various analytical methods including a multiscale observation by Transmission Electron Microscopy (TEM) and Laser Scanning Confocal Microscopy (LSCM) to understand the solution behavior of surfactant and oppositely charged polymer at both nano- and micrometer scale...
January 2, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27700041/determination-of-fragrance-allergens-by-ultraviolet-femtosecond-laser-ionization-mass-spectrometry
#20
Shimpei Shibuta, Tomoko Imasaka, Totaro Imasaka
The allergenic compounds listed in the Cosmetics Directive by the Scientific Committee for Consumer Safety were analyzed by gas chromatography combined with multiphoton ionization mass spectrometry using a femtosecond laser emitting at 200 and 267 nm as the ionization source. The limits of detection were less than 100 pg/μL for all of the compounds, permitting them to be measured in actual samples that were simply prepared by a 100-fold dilution of the original sample. The ionization process was investigated for the 26 allergens, some of which had no absorption band, even in the far-ultraviolet region...
October 4, 2016: Analytical Chemistry
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