keyword
MENU ▼
Read by QxMD icon Read
search

Bio mechanics

keyword
https://www.readbyqxmd.com/read/29679637/recent-stimulant-use-and-leukocyte-gene-expression-in-methamphetamine-users-with-treated-hiv-infection
#1
Adam W Carrico, Annesa Flentje, Kord Kober, Sulggi Lee, Peter Hunt, Elise D Riley, Steven Shoptaw, R N Elena Flowers, Samantha E Dilworth, Savita Pahwa, Bradley E Aouizerat
Stimulant use may accelerate HIV disease progression through biological and behavioral pathways. However, scant research with treated HIV-positive persons has examined stimulant-associated alterations in pathophysiologic processes relevant to HIV pathogenesis. In a sample of 55 HIV-positive, methamphetamine-using sexual minority men with a viral load less than 200 copies/mL, we conducted RNA sequencing to examine patterns of leukocyte gene expression in participants who had a urine sample that was reactive for stimulants (n = 27) as compared to those who tested non-reactive (n = 28)...
April 18, 2018: Brain, Behavior, and Immunity
https://www.readbyqxmd.com/read/29677783/investigation-of-surface-properties-of-fluorocarbon-films-produced-using-plasma-techniques
#2
Se-Bi Jung, Youn-Jeong Cho, Jihye Lee, Kang-Bong Lee, Yeonhee Lee
Different fluorocarbon thin films were deposited on Si substrates using two different plasma polymerization methods. Fluorine-containing hydrophobic thin films were obtained using inductively coupled plasma (ICP) and capacitively coupled plasma (CCP) with a mixture of fluorocarbon precursors (C2F6, C3F8, or c-C4F8) and an unsaturated hydrocarbon (C2H2). Different process parameters for plasma polymerization (e.g., processing time) were used to generate various fluorocarbon thin films. The hydrophobic properties and mechanical properties of the new products were measured using a profilometer, water contact angle measurements, pencil hardness, and a 90° peel test...
September 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29675528/well-dispersed-cellulose-nanocrystals-in-hydrophobic-polymers-by-in-situ-polymerization-for-synthesizing-highly-reinforced-bio-nanocomposites
#3
Shiyu Geng, Jiayuan Wei, Yvonne Aitomäki, Maxime Noël, Kristiina Oksman
In nanocomposites, dispersing hydrophilic nanomaterials in a hydrophobic matrix using simple and environmentally friendly methods remains challenging. Herein, we report a method based on in situ polymerization to synthesize nanocomposites of well-dispersed cellulose nanocrystals (CNCs) and poly(vinyl acetate) (PVAc). We have also shown that by blending this PVAc/CNC nanocomposite with poly(lactic acid) (PLA), a good dispersion of the CNCs can be reached in PLA. The outstanding dispersion of CNCs in both PVAc and PLA/PVAc matrices was shown by different microscopy techniques and was further supported by the mechanical and rheological properties of the composites...
April 20, 2018: Nanoscale
https://www.readbyqxmd.com/read/29675269/translation-of-remote-control-regenerative-technologies-for-bone-repair
#4
Hareklea Markides, Jane S McLaren, Neil D Telling, Noura Alom, E'atelaf A Al-Mutheffer, Richard O C Oreffo, Andrew Zannettino, Brigitte E Scammell, Lisa J White, Alicia J El Haj
The role of biomechanical stimuli, or mechanotransduction, in normal bone homeostasis and repair is understood to facilitate effective osteogenesis of mesenchymal stem cells (MSCs) in vitro. Mechanotransduction has been integrated into a multitude of in vitro bone tissue engineering strategies and provides an effective means of controlling cell behaviour towards therapeutic outcomes. However, the delivery of mechanical stimuli to exogenous MSC populations, post implantation, poses a significant translational hurdle...
2018: NPJ Regenerative Medicine
https://www.readbyqxmd.com/read/29675154/inedible-saccharides-a-platform-for-co-2-capturing
#5
REVIEW
Abdussalam K Qaroush, Hiba S Alshamaly, Shrouq S Alazzeh, Ream H Abeskhron, Khaleel I Assaf, Ala'a F Eftaiha
The economic viability of eco-friendly and renewable materials promotes the development of an alternative technology for climate change mitigation. Investigations reported over the past few years have allowed understanding the mechanism of action for a wide spectrum of saccharides toward carbon dioxide (CO2 ), in terms of reactivity, reversibility, stability and uptake. Exploiting bio-renewables, viz. , inedible saccharides, to reduce the anthropogenic carbon footprint upon providing a sustainable and promising technology that is of interest to different groups of scientists, to overcome demerits associated with the current state-of-the-art aqueous amine scrubbing agents, following a "green chemistry guideline", by employing materials with properties relevant to the environment toward sustainable development...
February 7, 2018: Chemical Science
https://www.readbyqxmd.com/read/29673143/injection-molding-and-mechanical-properties-of-bio-based-polymer-nanocomposites
#6
Maria Chiara Mistretta, Luigi Botta, Marco Morreale, Sebastiano Rifici, Manuela Ceraulo, Francesco Paolo La Mantia
The use of biodegradable/bio-based polymers is of great importance in addressing several issues related to environmental protection, public health, and new, stricter legislation. Yet some applications require improved properties (such as barrier or mechanical properties), suggesting the use of nanosized fillers in order to obtain bio-based polymer nanocomposites. In this work, bionanocomposites based on two different biodegradable polymers (coming from the Bioflex and MaterBi families) and two different nanosized fillers (organo-modified clay and hydrophobic-coated precipitated calcium carbonate) were prepared and compared with traditional nanocomposites with high-density polyethylene (HDPE) as matrix...
April 17, 2018: Materials
https://www.readbyqxmd.com/read/29670108/down-regulation-of-a-pro-apoptotic-pathway-regulated-by-pcaf-ada3-in-early-stage-gastric-cancer
#7
Daniella Brasacchio, Rita A Busuttil, Tahereh Noori, Ricky W Johnstone, Alex Boussioutas, Joseph A Trapani
The loss of p300/CBP-associated protein (PCAF) expression is associated with poor clinical outcome in gastric cancer, and a potential bio-marker for invasive and aggressive tumors. However, the mechanism linking loss of PCAF to the onset of gastric cancer has not been identified. Given that PCAF and its binding partner transcriptional adaptor protein 3 (ADA3) were recently shown to regulate the intrinsic (mitochondrial) pathway to apoptosis via epigenetic regulation of phosphofurin acidic cluster sorting proteins 1 and 2 (PACS1, PACS2), we analyzed PCAF, ADA3, and PACS1/2 expression in 99 patient-matched surgical samples ranging from normal gastric mucosa, through pre-malignant chronic gastritis and intestinal metaplasia to stage I-III invasive cancers...
April 18, 2018: Cell Death & Disease
https://www.readbyqxmd.com/read/29667669/structural-characterization-and-antitumor-activity-of-a-novel-se-polysaccharide-from-selenium-enriched-cordyceps-gunnii
#8
Huiqing Sun, Zhenyuan Zhu, Yali Tang, Yuanyuan Ren, Qiaoying Song, Yun Tang, Yongmin Zhang
Selenium (Se) has been recognized as an essential element. Animals and humans absorb and retain more organic Se than inorganic Se. Bio-transformation is a major approach to transform inorganic Se to organic Se. Cordyceps gunnii (C. gunnii), well known as a Chinese edible and medicinal fungus, has a variety of biological functions. C. gunnii and selenium were combined through liquid-fermentation to obtain selenium-enriched C. gunnii. A novel Se-polysaccharide (SeCPS-II) was extracted from selenium-enriched C...
April 18, 2018: Food & Function
https://www.readbyqxmd.com/read/29667400/magnetically-characterized-molecular-lubrication-between-bio-functionalized-surfaces
#9
Xinghao Hu, Sri Ramulu Torati, Jonghwan Yoon, Byeonghwa Lim, Kunwoo Kim, CheolGi Kim
We demonstrate an efficient approach for quantifying frictional forces (sub-pN) at nano-bio interfaces by controlled magnetic forces, which is based on simultaneous measurements of critical frequencies for streptavidin-coupled magnetic particles. The maximum phase angle, being corresponded with the critical frequency, is formulated in terms of magnetic, frictional and viscous forces of the particles on DNA and SiO2 functionalized micromagnet arrays. The streptavidin/DNA interface shows lower friction as an enhanced lubrication than the streptavidin/SiO2 interface, which is indicated by the lower transition field of quasi-static motion, the larger ratio of dynamic particles, and also the higher velocity of the particles...
April 18, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29666792/steady-state-linear-and-non-linear-optical-spectroscopy-of-organic-chromophores-and-bio-macromolecules
#10
REVIEW
Marco Marazzi, Hugo Gattuso, Antonio Monari, Xavier Assfeld
Bio-macromolecules as DNA, lipid membranes and (poly)peptides are essential compounds at the core of biological systems. The development of techniques and methodologies for their characterization is therefore necessary and of utmost interest, even though difficulties can be experienced due to their intrinsic complex nature. Among these methods, spectroscopies, relying on optical properties are especially important to determine their macromolecular structures and behaviors, as well as the possible interactions and reactivity with external dyes-often drugs or pollutants-that can (photo)sensitize the bio-macromolecule leading to eventual chemical modifications, thus damages...
2018: Frontiers in Chemistry
https://www.readbyqxmd.com/read/29665287/identification-of-nanoparticles-and-nanosystems-in-biological-matrices-with-scanning-probe-microscopy
#11
REVIEW
Livia Angeloni, Melania Reggente, Daniele Passeri, Marco Natali, Marco Rossi
Identification of nanoparticles and nanosystems into cells and biological matrices is a hot research topic in nanobiotechnologies. Because of their capability to map physical properties (mechanical, electric, magnetic, chemical, or optical), several scanning probe microscopy based techniques have been proposed for the subsurface detection of nanomaterials in biological systems. In particular, atomic force microscopy (AFM) can be used to reveal stiff nanoparticles in cells and other soft biomaterials by probing the sample mechanical properties through the acquisition of local indentation curves or through the combination of ultrasound-based methods, like contact resonance AFM (CR-AFM) or scanning near field ultrasound holography...
April 17, 2018: Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
https://www.readbyqxmd.com/read/29665253/hairy-graphenes-wrapping-nanocellulose-nets-around-graphene-oxide-sheets
#12
Rui Xiong, Ho Shin Kim, Volodymyr F Korolovych, Shuaidi Zhang, Yaroslava Yingling, Vladimir V Tsukruk
Constructing advanced functional nanomaterials with pre-designed organized morphologies from low-dimension synthetic and biological components is extremely challenging because of complex inter-component interactions, high-aspect ratios, flexible shapes, crumpling instabilities and limited common wet-chemistry processing conditions. Herein, we report an efficient and universal amphiphilicity-driven assembly strategy to construct "hairy" flexible hybrid nanosheets with the net of 1D cellulose nanofibers (CNFs) conformally wrapped around 2D graphene oxide (GO) monolayers...
April 17, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29664607/polyserotonin-nanoparticles-as-multifunctional-materials-for-biomedical-applications
#13
Nako Nakatsuka, Mohammad Mahdi Hasani-Sadrabadi, Kevin M Cheung, Thomas D Young, Ghasem Bahlakeh, Alireza Moshaverinia, Paul S Weiss, Anne M Andrews
Serotonin-based nanoparticles represent a class of previously unexplored multifunctional nanoplatforms with potential biomedical applications. Serotonin, under basic conditions, self-assembles into monodisperse nanoparticles via autoxidation of serotonin monomers. To demonstrate potential applications of polyserotonin nanoparticles for cancer therapeutics, we show that these particles are biocompatible, exhibit photothermal effects when exposed to near-infrared radiation, and load the chemotherapeutic drug doxorubicin releasing it contextually and responsively in specific microenvironments...
April 17, 2018: ACS Nano
https://www.readbyqxmd.com/read/29663798/avoiding-antibiotic-inactivation-in-mycobacterium-tuberculosis-by-rv3406-through-strategic-nucleoside-modification
#14
Matthew R Bockman, Curtis A Engelhart, Surendra Dawadi, Peter Larson, Divya Tiwari, David M Ferguson, Dirk Schnappinger, Courtney C Aldrich
5'-[ N-(d-biotinoyl)sulfamoyl]amino-5'-deoxyadenosine (Bio-AMS, 1) possesses selective activity against Mycobacterium tuberculosis ( Mtb) and arrests fatty acid and lipid biosynthesis through inhibition of the Mycobacterium tuberculosis biotin protein ligase ( MtBPL). Mtb develops spontaneous resistance to 1 with a frequency of at least 1 × 10-7 by overexpression of Rv3406, a type II sulfatase that enzymatically inactivates 1. In an effort to circumvent this resistance mechanism, we describe herein strategic modification of the nucleoside at the 5'-position to prevent enzymatic inactivation...
April 17, 2018: ACS Infectious Diseases
https://www.readbyqxmd.com/read/29663540/extreme-toughening-of-soft-materials-with-liquid-metal
#15
Navid Kazem, Michael D Bartlett, Carmel Majidi
Soft and tough materials are critical for engineering applications in medical devices, stretchable and wearable electronics, and soft robotics. Toughness in synthetic materials is mostly accomplished by increasing energy dissipation near the crack tip with various energy dissipation techniques. However, bio-materials exhibit extreme toughness by combining multi-scale energy dissipation with the ability to deflect and blunt an advancing crack tip. Here, we demonstrate a synthetic materials architecture that also exhibits multi-modal toughening, whereby embedding a suspension of micron sized and highly deformable liquid metal (LM) droplets inside a soft elastomer, the fracture energy dramatically increases by up to 50x (from 250 ± 50 J m-2 to 11,900 ± 2600 J m-2 ) over an unfilled polymer...
April 16, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29661781/relation-of-aortic-stiffness-to-left-ventricular-remodelling-in-younger-adults-with-type-2-diabetes
#16
Gaurav S Gulsin, Daniel J Swarbrick, William H Hunt, Eylem Levelt, Matthew Pm Graham-Brown, Kelly S Parke, Joanne V Wormleighton, Florence Y Lai, Thomas Yates, Emma G Wilmot, David R Webb, Melanie J Davies, Gerry P McCann
Individuals with type 2 diabetes have a three-to-five-fold increased risk of developing heart failure. Diabetic cardiomyopathy is typified by left ventricular (LV) concentric remodelling, which is a recognised predictor of adverse cardiovascular events. Although the mechanisms underlying LV remodelling in type 2 diabetes are unclear, progressive aortic stiffening may be a key determinant. The aim of this study was to assess the relationship between aortic stiffness and LV geometry in younger adults with type 2 diabetes, using multiparametric cardiovascular magnetic resonance imaging...
April 16, 2018: Diabetes
https://www.readbyqxmd.com/read/29659911/comparative-bio-efficacy-and-synergism-of-new-generation-polyfluorobenzyl-and-conventional-pyrethroids-against-culex-quinquefasciatus-diptera-culicidae
#17
Manas Sarkar, Ambadas Akulwad, Rajendra Kshirsagar, Siva Muthukrishnan
Intensive exposure to insecticides has resulted in the evolution of insecticide resistance in the mosquitoes. We tested the bio-efficacy of two Culex quinquefasciatus Say (Diptera: Culicidae) laboratory strains differentially bio-responsive to pyrethroids to understand the comparative efficacy of different polyfluorobenzyle and conventional pyrethroid molecules and the role of piperonyl butoxide (PBO) in synergizing these molecules in increased tolerance of mosquitoes to these molecules. We have taken deltamethrin (α-cyano pyrethroid with phenoxybenzyl moiety); permethrin (phenoxybenzyl pyrethroid without an α-cyano group); transfluthrin, dimefluthrin, metofluthrin, and meperfluthrin (polyfluorinated benzyl compounds); and prallethrin (modified cyclopentadienone compound) for this study...
April 12, 2018: Journal of Economic Entomology
https://www.readbyqxmd.com/read/29657822/increasing-cell-device-adherence-using-cultured-insect-cells-for-receptor-based-biosensors
#18
Daigo Terutsuki, Hidefumi Mitsuno, Takeshi Sakurai, Yuki Okamoto, Agnès Tixier-Mita, Hiroshi Toshiyoshi, Yoshio Mita, Ryohei Kanzaki
Field-effect transistor (FET)-based biosensors have a wide range of applications, and a bio-FET odorant sensor, based on insect (Sf21) cells expressing insect odorant receptors (ORs) with sensitivity and selectivity, has emerged. To fully realize the practical application of bio-FET odorant sensors, knowledge of the cell-device interface for efficient signal transfer, and a reliable and low-cost measurement system using the commercial complementary metal-oxide semiconductor (CMOS) foundry process, will be indispensable...
March 2018: Royal Society Open Science
https://www.readbyqxmd.com/read/29656220/synergistic-effect-of-the-combined-bio-fungicides-%C3%AE%C2%B5-poly-l-lysine-and-chitooligosaccharide-in-controlling-grey-mould-botrytis-cinerea-in-tomatoes
#19
Guangzheng Sun, Qichao Yang, Ancheng Zhang, Jia Guo, Xinjie Liu, Yang Wang, Qing Ma
The antifungal properties and the induction of resistance by ε-poly-l-lysine (ε-PL) and chitooligosaccharide (COS) were examined to find an alternative to synthetic fungicides currently used in the control of the devastating fungal pathogen Botrytis cinerea, the causal agent of grey mould disease of tomatoes. As presented herein, this combined treatment (200 mg/L ε-PL + 400 mg/L COS) was found to have optimal in vitro antifungal activities, achieving an inhibition rate of 90.22%. In vivo assays with these combined bio-fungicides, under greenhouse conditions using susceptible tomato plants, demonstrated good protection against severe grey mould...
April 4, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29655884/lignin-based-hydrogels-with-super-swelling-capacities-for-dye-removal
#20
Juan Domínguez-Robles, María Soledad Peresin, Tarja Tamminen, Alejandro Rodríguez, Eneko Larrañeta, Anna-Stiina Jääskeläinen
Lignin is a complex natural polymer and it is one of the main constituent of the lignocellulosic biomass. Moreover, it is a bio-renewable material and it is available in large amounts as by-product of residues from the wood and paper industries. Lignin-based hydrogels with high swelling capabilities were prepared by crosslinking poly (methyl vinyl ether co‑maleic acid) and different technical lignins in ammonium and sodium hydroxide solutions. The produced hydrogels showed a wide range of water absorption capacities varying from 13 to 130 g of water per 1 g of sample...
April 12, 2018: International Journal of Biological Macromolecules
keyword
keyword
27350
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"