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Kiwoung Yang, Ujjal Kumar Nath, Manosh Kumar Biswas, Md Abdul Kayum, Go-Eun Yi, Jonghoon Lee, Tae-Jin Yang, Ill-Sup Nou
Plant mitochondrial genomes (mtDNAs) vary in sequence structure. We assembled the Brassica oleracea var. capitata mtDNA using a mean coverage depth of 25X whole genome sequencing (WGS) and confirmed the presence of eight contigs/fragments by BLASTZ using the previously reported KJ820683 and AP012988 mtDNA as reference. Assembly of the mtDNA sequence reads resulted in a circular structure of 219,975 bp. Our assembled mtDNA, NCBI acc. no. KU831325, contained 34 protein-coding genes, 3 rRNA genes, and 19 tRNA genes with similarity to the KJ820683 and AP012988 reference mtDNA...
2018: PloS One
A-Ra Hong, Youngsun Kim, Tae Sup Lee, Sehoon Kim, Kwangyeol Lee, Gayoung Kim, Ho Seong Jang
In this study, intense single-band red-emitting upconversion nanophosphors (UCNPs) excited with 800 nm near infrared (NIR) light are reported. When a NaYF4 :Nd,Yb active-shell is formed on the 12.7 nm-sized NaGdF4 :Yb,Ho,Ce UCNP core, the core/shell (C/S) UCNPs show tunable emission from green to red depending on the Ce3+ concentration under excitation with 800 nm NIR light. Thirty mol% Ce3+ -doped C/S UCNPs exhibit single-band red emission peaking at 644 nm via a5 F5 →5 I8 transition of Ho3+ . A high Nd3+ concentration in the shell results in strong absorption at around 800 nm NIR light even though the shell thickness is not large, and small-sized C/S UCNPs (16...
March 16, 2018: ACS Applied Materials & Interfaces
Bingwen Zhang, Qinfang Zhang, Yujie Bai
A new monolayer MnC<sub>2</sub> was predicted as a stable 2D material associated with the
 result of phonon and AIMD calculations. The in-plane young's modulus is 73.6 N/m,
 which is about 20% of graphene. The monolayer MnC<sub>2</sub> is antiferromagnetic with a
 Neil temperature around 280K and from the dirac point of the electronic band we got
 the fermi velocity of 5.37×10<sup>5</sup> m/s showing excellent electronic transport property...
March 15, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Yimei Ma, Xizhou An, Xianmin Guan, Qinglin Kong, Yanzhen Wang, Pengfei Li, Yan Meng, Yinghui Cui, Xianhao Wen, Yuxia Guo, Yali Shen, Jie Yu
Phosphoribosyl pyrophosphate synthetase 1 (PRPS1) is closely associated with a number of diseases; however, its influence in B-cell acute lymphoblastic leukemia (B-ALL) and the potential molecular mechanisms involved remain unclear. The present study aimed to evaluate the expression of PRPS1 in Chinese children with B-ALL and to investigate the mechanism of action of PRPS1 in this disease. A Cell Counting Kit-8 (CCK-8) assay was performed to examine the proliferation of B-ALL Sup-B15 and Raji cells, and flow cytometric analysis was conducted to determine the cell cycle distribution and rate of apoptosis...
April 2018: Oncology Letters
B Borghese, P Santulli, L Marcellin, C Chapron
Endometriosis and adenomyosis are histologically defined. The frequency of endometriosis cannot be precisely estimated in the general population. Endometriosis is considered a disease when it causes pain and/or infertility. Endometriosis is a heterogeneous disease with three well-recognized subtypes that are often associated with each other: superficial endometriosis (SUP), ovarian endometrioma (OMA), and deep infiltrating endometriosis (DIE). DIE is frequently multifocal and mainly affects the following structures: the uterosacral ligaments, the posterior vaginal cul-de-sac, the bladder, the ureters, and the digestive tract (rectum, recto-sigmoid junction, appendix)...
March 11, 2018: Gynecologie, Obstetrique, Fertilite & Senologie
Jeong-Ik Park, Ki-Hun Kim, Hong-Jin Kim, Daniel Cherqui, Olivier Soubrane, David Kooby, Chinnusamy Palanivelu, Albert Chan, Young Kyoung You, Yao-Ming Wu, Kuo-Hsin Chen, Goro Honda, Xiao-Ping Chen, Chung-Ngai Tang, Ji Hoon Kim, Yang Seok Koh, Young-In Yoon, Kai Chi Cheng, Tran Cong Duy Long, Gi Hong Choi, Yuichiro Otsuka, Tan To Cheung, Taizo Hibi, Dong-Sik Kim, Hee Jung Wang, Hironori Kaneko, Dong-Sup Yoon, Etsuro Hatano, In Seok Choi, Dong Wook Choi, Ming-Te Huang, Sang Geol Kim, Sung-Gyu Lee
The application of laparoscopy for liver surgery is rapidly increasing and the past few years have demonstrated a shift in paradigm with a trend towards more extended and complex resections. The development of instruments and technical refinements with the effective use of magnified caudal laparoscopic views have contributed to the ability to overcome the limitation of laparoscopic liver resection. The Endoscopic and Laparoscopic Surgeons of Asia (ELSA) Visionary Summit 2017 and the 3rd Expert Forum of Asia-Pacific Laparoscopic Hepatectomy organized hepatobiliary pancreatic sessions in order to exchange surgical tips and tricks and discuss the current status and future perspectives of laparoscopic hepatectomy...
February 2018: Annals of Hepato-Biliary-Pancreatic Surgery
Eunyoung Bang, Boyoung Lee, Joon-Oh Park, Yooncheol Jang, Aekyong Kim, Sungwuk Kim, Hee-Sup Shin
In recent years, as the aging population grows, aging-induced cognitive impairments including dementia and Alzheimer's disease (AD) have become the biggest challenges for global public health and social care. Therefore, the development of potential therapeutic drugs for aging-associated cognitive impairment is essential. Metabolic dysregulation has been considered to be a key factor that affects aging and dementia. Adenosine monophosphate (AMP)-activated protein kinase (AMPK) is a primary sensor of cellular energy states and regulates cellular energy metabolism...
February 2018: Experimental Neurobiology
Kanij Rukshana Sumi, Soo Cheol Kim, Jewel Howlader, Won Kyo Lee, Kap Seong Choi, Hoy-Taek Kim, Jong-In Park, Ill-Sup Nou, Kang Hee Kho
In this study, an 1888-bp carbonic anhydrase XII (CA XII) sequence was cloned from the brain of the pufferfish, Takifugu rubripes . The cloned sequence contained a coding region of 1470-bp, which was predicted to translate into a protein of 490 amino acid residues. The predicted protein showed between 68-56% identity with the large yellow croaker ( Larimichthys crocea ), tilapia ( Oreochromis niloticus ), and Asian arowana ( Scleropages formosus ) CA XII proteins. It also exhibited 36% and 53% identity with human CA II and CA XII, respectively...
March 13, 2018: International Journal of Molecular Sciences
Youl-Ri Kim, Jin-Sup Eom, Jennie Leppanen, Monica Leslie, Janet Treasure
BACKGROUND: Bulimia nervosa (BN) is characterized by binge eating and emotional dysregulation including increased negative affectivity (anger, anxiety). The aim of this study was to examine the effect of oxytocin on attentional processes towards anger in patients with BN. METHOD: The study design consisted of a double-blind, placebo-controlled within-subject crossover, single dose experiment. Sixty-four women (31 patients with BN and 33 healthy comparisons) completed self-reported measures to evaluate emotional difficulties and were administered a single dose of intranasal oxytocin (40IU) or placebo followed by a visual probe detection task to examine attentional orienting to angry or happy faces...
March 3, 2018: Psychoneuroendocrinology
Martin P Poirier, Sean R Notley, Andreas D Flouris, Glen P Kenny
We examined if physical characteristics could be used to predict cooling time during cold water immersion (CWI, 2°C) following exertional hyperthermia (rectal temperature ≥39.5°C) in a physically heterogeneous group of men and women (n=62). Lean body mass was the only significant predictor of cooling time following CWI (R<sup>2</sup>=0.137; P<0.001); however that prediction did not provide the precision (mean residual square error: 3.18±2.28 min) required to act as a safe alternative to rectal temperature measurements...
March 12, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
Samuel T Orange, Phil Marshall, Leigh A Madden, Rebecca V Vince
This study compared the effects of a 4-week supervised (SUP) and unsupervised (UNSUP) resistance training programme followed by 12 weeks of detraining (DET). Thirty-six healthy aging adults (age: 53.6 ± 3.6 years; body mass index: 28.3 ± 5.1 kg/m) were randomly allocated to a SUP group (n = 17) or an UNSUP group (n = 19). Participants completed three training sessions per week using resistance bands and body weight movements. Measures of physical performance were administered at baseline, at the end of the training programme, and after the DET period...
March 6, 2018: Journal of Strength and Conditioning Research
Junli Wang, Lei Chen, Chenxi Dou, Haiting Yan, Lingjie Meng, Zhiyi Wei
In this work, we fabricate the Mo&lt;sub&gt;0.5&lt;/sub&gt;W&lt;sub&gt;0.5&lt;/sub&gt;S&lt;sub&gt;2&lt;/sub&gt; by microwave-assisted solvothermal method, and report the Q-switched Yb-doped fiber lasers using Mo&lt;sub&gt;0.5&lt;/sub&gt;W&lt;sub&gt;0.5&lt;/sub&gt;S&lt;sub&gt;2&lt;/sub&gt; nanosheets polymer film and tapered fiber as the saturable absorbers (SAs). The modulation depth and saturable intensity of the film SA are 5...
March 12, 2018: Nanotechnology
Hitomi Mukaibo, Tonghui Wang, Victor H Perez-Gonzalez, Jirachai Getpreecharsawas, Jack T Wurzer, Blanca Lapizco-Encinas, James L McGrath
Insulator-based dielectrophoresis (iDEP) is a simple, scalable mechanism that can be used for directly manipulating particle trajectories in pore-based filtration and separation processes. However, iDEP manipulation of nanoparticles presents unique challenges as the dielectrophoretic force (&lt;b&gt;&lt;i&gt;F&lt;/i&gt;&lt;/b&gt;&lt;sub&gt;DEP&lt;/sub&gt;) exerted on the nanoparticles can easily be overshadowed by opposing kinetic forces. In this study, a molecularly thin, SiN-based nanoporous membrane (NPN) is explored as a breakthrough technology that enhances &lt;b&gt;&lt;i&gt;F&lt;/i&gt;&lt;/b&gt;&lt;sub&gt;DEP&lt;/sub&gt;...
March 12, 2018: Nanotechnology
Satyendra Nath Gupta, Anjali Singh, Koushik Pal, D Victor S Muthu, Chandra Shekhar, Moaz A ElGhazali, Pavel Naumov, Sergey Medvedev, Claudia Felser, Umesh V Waghmare, A K Sooda
High pressure Raman, resistivity and synchrotron x-ray diffraction studies on Weyl semimetals NbAs and TaAs have been carried out along with density functional theoretical (DFT) analysis to explain pressure-induced structural and electronic topological phase transitions. The frequencies of first order Raman modes harden with increasing pressure, exhibiting a slope change at P&lt;sub&gt;c&lt;/sub&gt;&lt;sup&gt;Nb&lt;/sup&gt; ~15 GPa for NbAs and P&lt;sub&gt;c&lt;/sub&gt;&lt;sup&gt;Ta&lt;/sup&gt; ~16 GPa for TaAs...
March 12, 2018: Journal of Physics. Condensed Matter: An Institute of Physics Journal
Jun Young Kim, Jae Yeol Kwon, Moon Seok Kim, Jeong Jae Lee, Il Sup Kim, Jae Taek Hong
OBJECTIVE: To compare the morphometry of subaxial cervical spine between cerebral palsy (CP) and normal control. METHODS: We retrospectively analyzed 72 patients with CP, as well as 72 patients from normal population. The two groups were matched for age, sex, and body mass index. Pedicle, lateral mass (LM), and vertebral foramen were evaluated using computed tomography (CT) imaging. Pedicle diameter, LM height, thickness, width and vertebral foramen asymmetry (VFA) were measured and compared between the two groups...
March 2018: Journal of Korean Neurosurgical Society
Fan Wu, Qiquan Qiao, Behzad Bahrami, Ke Chen, Rajesh Pathak, Yanhua Tong, Xiaoyi Li, Tiansheng Zhang, Ronghua Jian
We present a method to synthesize CuO nanorod array/TiO&lt;sub&gt;2&lt;/sub&gt; nanocrystals bulk heterojunction on fluorin-tin-oxide (FTO) glass, in which single-crystalline p-type semiconductor of the CuO nanorod array is grown on the FTO glass by hydrothermal reaction and the n-type semiconductor of the TiO&lt;sub&gt;2&lt;/sub&gt; precursor is filled into the CuO nanorods to form well-organized nano-interpenetrating bulk heterojunction after air annealing. The interface charge transfer in CuO nanorod array/TiO&lt;sub&gt;2&lt;/sub&gt; heterojunction is studied by Kelvin probe force microscopy (KPFM)...
March 9, 2018: Nanotechnology
Zachariah J Sperry, Kyounghwan Na, Saman S Parizi, Hillel J Chiel, John Seymour, Euisik Yoon, Tim M Bruns
The dorsal root ganglia (DRG) are promising nerve structures for sensory neural interfaces because they provide centralized access to primary afferent cell bodies and spinal reflex circuitry. In order to harness this potential, new electrode technologies are needed which take advantage of the unique properties of DRG, specifically the high density of neural cell bodies at the dorsal surface. Here we report initial &lt;i&gt;in vivo&lt;/i&gt; results from the development of a flexible non-penetrating polyimide electrode array interfacing with the surface of ganglia...
March 9, 2018: Journal of Neural Engineering
Jun-Hyun Kim, Sun-Young Lee, Sang Pyo Lee, Jeong Hwan Kim, In-Kyung Sung, Hyung Seok Park, Chan Sup Shim, Hye Seung Han
BACKGROUND: Helicobacter pylori is unevenly distributed in hypochlorhydric environments. The study aim was to elucidate the risk factors for a negative Giemsa staining finding in seropositive subjects by measuring the secretory ability of the stomach. METHODS: Subjects aged over 18 years were included consecutively after endoscopic biopsy at gastric lesions with color or structural changes. Blood was sampled for the serum pepsinogen (PG) assay and H. pylori serology test...
March 8, 2018: Helicobacter
Minwoo Cho, Jee Hyun Kim, Hyoun Joong Kong, Kyoung Sup Hong, Sungwan Kim
PURPOSE: The colonoscopy adenoma detection rate depends largely on physician experience and skill, and overlooked colorectal adenomas could develop into cancer. This study assessed a system that detects polyps and summarizes meaningful information from colonoscopy videos. METHODS: One hundred thirteen consecutive patients had colonoscopy videos prospectively recorded at the Seoul National University Hospital. Informative video frames were extracted using a MATLAB support vector machine (SVM) model and classified as bleeding, polypectomy, tool, residue, thin wrinkle, folded wrinkle, or common...
March 8, 2018: International Journal of Colorectal Disease
Hyung-Sup Shim, Byung Yeun Kwon, Bommie F Seo, Ho Kwon, Sung-No Jung
BACKGROUND: The treatment of choice for fingertip amputation is replantation to restore function and aesthetics. The purpose of this study was to compare the success rates and salvage periods between patients with Tamai's zone I amputation injuries treated with bony fixation and suture fixation. METHODS: Fifty-five patients with Tamai's zone I amputations with bony involvement were included in this study. The patients were allocated randomly to two groups treated by bony fixation with Kirschner (K-)wire and suture fixation, respectively...
February 22, 2018: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
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