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https://www.readbyqxmd.com/read/29315657/dysautonomy-in-different-death-risk-groups-rassi-score-in-patients-with-chagas-heart-disease
#1
Catherine Masiel Merejo Peña, Michel Silva Reis, Basílio de Bragança Pereira, Emília Matos do Nascimento, Roberto Coury Pedrosa
BACKGROUND: It has been difficult to prove that the "catecholamine-induced cardiomyopathy" contributes to the mechanism of sudden cardiac death in Chagas heart disease. Also, it is almost impossible to rule out the possibility that is not involved in the process. More importantly, the vagal-cholinergic pathway in the ventricle plays a direct role in the prevention of the initiation of complex ventricular arrhythmias, including non-sustained ventricular tachycardia, ventricular fibrillation responsible for sudden death...
January 5, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29240992/heart-rate-recovery-and-diastolic-blood-pressure-ratio-on-the-treadmill-test-predict-an-induction-and-recurrence-of-vasovagal-syncope
#2
Yu Jeong Choi, Ki-Woon Kang, Sang Hyun Jang, Jae Guk Kim, Soo Joo Lee, Kyung Tea Jung
Background/Aims: The induction and recurrence of syncope is a concerning situation that could be unpredicted in the vasovagal syncope (VVS). We investigated a simple predictor for the induced and recurrent VVS during Head-Up table-tilt Test (HUT) and clinically follow-up. Methods: The 143 consecutive patients with VVS (age 31 ± 19 years, 33 male) who referred by a cardiologist or neurologist and had undergone an echocardiogram, HUT, and a treadmill exercise test (TMT) were recruited and clinically follow-up...
December 18, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/29240320/time-has-not-passed-for-the-tilt-table-test
#3
Jani Pirinen, Markku Walamies
INTRODUCTION: The tilt table test is used for determining the loss of consciousness, and in the case of reflex syncope, for gaining insight into the circulatory mechanism. In 2015, all tilt tests within the Hospital District of Helsinki and Uusimaa (HUS) were performed in the clinical physiology unit of the HUS Medical Imaging Center at Peijas Hospital. METHODS: The patients' medical history, circulation monitor printouts, and medical reports were recorded from all tilt tests carried out during 2015...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29189552/autonomic-reflex-screen-test-abnormalities-in-cold-induced-sweating-syndrome-type-1
#4
Ahmed M El-Dokla, Jannatul Ferdous, Sara T Ali, Khondoker Alam
Cold-induced sweating syndrome (CISS) is a rare autosomal recessive disease due to mutation in the Cytokine receptor-like factor 1 (CRLF1). The characteristic symptom of CISS is the tendency to sweat profusely especially in the upper body and hands when the patient is exposed to cold temperature. We sought to first report the findings of autonomic reflex screen in a case of CISS type 1 with Cytokine receptor-like factor 1 mutation. Valsalva morphology, Valsalva ratio, and heart rate response to deep breathing were normal for the patient's age...
December 2017: Journal of Clinical Neuromuscular Disease
https://www.readbyqxmd.com/read/29165784/interventions-for-managing-skeletal-muscle-spasticity-following-traumatic-brain-injury
#5
REVIEW
Anneliese Synnot, Marisa Chau, Veronica Pitt, Denise O'Connor, Russell L Gruen, Jason Wasiak, Ornella Clavisi, Loyal Pattuwage, Kate Phillips
BACKGROUND: Skeletal muscle spasticity is a major physical complication resulting from traumatic brain injury (TBI), which can lead to muscle contracture, joint stiffness, reduced range of movement, broken skin and pain. Treatments for spasticity include a range of pharmacological and non-pharmacological interventions, often used in combination. Management of spasticity following TBI varies from other clinical populations because of the added complexity of behavioural and cognitive issues associated with TBI...
November 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29153480/spatial-orientation-and-postural-control-in-patients-with-parkinson-s-disease
#6
E Pawlitzki, C Schlenstedt, N Schmidt, I Rotkirch, F Gövert, G Hartwigsen, K Witt
Postural instability is one of the most disabling and risky symptoms of advanced Parkinson's disease (PD). The purpose of this study was to investigate whether and how this is mediated by a centrally impaired spatial orientation. Therefore, we performed a spatial orientation study in 21 PD patients (mean age 68years, SD 8.5 years, 9 women) in a medically on condition and 21 healthy controls (mean age 68.9years, SD 5.5years, 14 women). We compared their spatial responses to the horizontal axis (Sakashita's visual target cancellation task), the vertical axis (bucket-test), the sagittal axis (tilt table test) and postural stability using the Fullerton Advanced Balance Scale (FAB)...
November 13, 2017: Gait & Posture
https://www.readbyqxmd.com/read/29023991/correlation-of-head-up-tilt-table-test-time-interval-with-future-risk-of-recurrent-syncope
#7
Bhanwar L Ranwa, Priti K, Sajal Gupta
BACKGROUND: Head-up tilt table test (HUTT) is widely used for investigation of syncope and presyncope. Time required for positive response has a probable relationship to the sensitivity of neural reflex mechanism underlying syncope. METHODS: We evaluated patients with history of syncope. Group A included patients with recurrent syncope defined as 2 or more episodes of syncope and group B included those with 1 episode of syncope. Time required for the test to become positive in both the groups was analyzed...
October 10, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28986003/postural-tachycardia-in-hypermobile-ehlers-danlos-syndrome-a-distinct-subtype
#8
Mitchell G Miglis, Brittany Schultz, Srikanth Muppidi
INTRODUCTION: It is not clear if patients with postural tachycardia syndrome (POTS) and Ehlers-Danlos syndrome (hEDS) differ from patients with POTS due to other etiologies. We compared the results of autonomic testing and healthcare utilization in POTS patients with and without hEDS. METHODS: Patients with POTS+hEDS (n=20) and POTS controls without hypermobility (n=20) were included in the study. All patients underwent autonomic testing, and the electronic medical records were reviewed to determine the number and types of medications patients were taking, as well as the number of outpatient, emergency department, and inpatient visits over the prior year...
October 2, 2017: Autonomic Neuroscience: Basic & Clinical
https://www.readbyqxmd.com/read/28960795/gastric-myoelectrical-and-neurohormonal-changes-associated-with-nausea-during-tilt-induced-syncope
#9
G L Heyer, L H Boles, R A Harvey, M J Cismowski
BACKGROUND: Nausea is a common prodromal symptom of neurally mediated syncope, but the biological factors linking nausea with syncope have not been studied. We aimed to characterize nausea during tilt-induced syncope by exploring related changes in gastric myoelectrical activity and plasma epinephrine, norepinephrine, and vasopressin concentrations across study phases of recumbency, tilt, syncope, and recovery. METHODS: Electrogastrographic and plasma hormone changes were compared between patients with tilt-induced syncope and nausea (n = 18) and control subjects (n = 6) without symptoms or hemodynamic changes during tilt-table testing...
September 27, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28939425/kinematic-analysis-of-a-drinking-task-in-chronic-hemiparetic-patients-using-features-analysis-and-statistical-parametric-mapping
#10
Gabriela Lopes Santos, Thiago Luiz Russo, Angela Nieuwenhuys, Davide Monari, Kaat Desloovere
OBJECTIVE: To compare sitting posture and movement strategies between chronic hemiparetic and healthy subjects while performing a drinking task using Statistical Parametric Mapping (SPM) and feature analysis. DESIGN: Cross-sectional study. SETTING: Department of Physical Therapy of University. PARTICIPANTS: Thirteen chronic hemiparetic and thirteen healthy individuals matched for gender and age. INTERVENTION: Not applicable...
September 19, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28904457/delayed-orthostatic-hypotension-a-pilot-study-from-india
#11
Arun Grace Roy, Siby Gopinath, Suresh Kumar, Sudheeran Kannoth, Anand Kumar
INTRODUCTION: Orthostatic hypotension is defined as a sustained decrease in systolic blood pressure of 20 mm Hg or a decrease in diastolic blood pressure of 10 mm Hg within three minutes of standing compared with blood pressure from the sitting or supine position or by head-up tilt-table testing (1). When sustained blood pressure (BP) drop is after three minutes of upright posture it is called delayed orthostatic hypotension (delayed OH) (2). AIM OF THE STUDY: To detect the incidence of delayed orthostatic hypotension in patients referred to our autonomic lab...
July 2017: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/28885987/theoretical-and-experimental-comparison-of-lag-based-and-time-based-exponential-moving-average-models-of-qt-hysteresis
#12
Vincent Jacquemet, Hugo Gravel, Daniel Curnier, Alain Vinet
In the electrocardiogram, adaptation of the QT interval to variations in heart rate is not instantaneous. Quantification of this hysteresis phenomenon relies on mathematical models describing the relation between the RR and QT time series.These models reproduce hysteresis through an effective RR interval computed as a linear combination of the history of past RR intervals. This filter depends on a time constant parameter that may be used as biomarker. The most common hysteresis model is based on an autoregressive filter with an impulse response that decreases exponentially with the beat number (lag-based model)...
September 8, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28827487/clinical-and-laboratory-profiles-of-idiopathic-small-fiber-neuropathy-in-children-case-series
#13
Jafar Kafaie, Ali Al Balushi, Minsoo Kim, Alan Pestronk
The role of autoimmune mechanisms in idiopathic small fiber neuropathy (SFN) is not completely understood. Serum IgM binding to trisulfated disaccharide IdoA2S-GlcNS-6S (TS-HDS) and IgG to fibroblast growth factor receptor 3 were associated with sensory motor polyneuropathies and sensory neuronopathy among others. In this retrospective case review, we describe the clinical and laboratory findings of idiopathic SFN in a small cohort of pediatric patients. Eight children were diagnosed with SFN clinically and confirmed by reduced epidermal nerve fiber density...
September 2017: Journal of Clinical Neuromuscular Disease
https://www.readbyqxmd.com/read/28795253/autonomic-responses-to-head-up-tilt-test-in-children-with-autism-spectrum-disorders
#14
Véronique-Aurélie Bricout, Marion Pace, Léa Dumortier, Anne Favre-Juvin, Michel Guinot
Autism Spectrum Disorders (ASD) is a group of neurodevelopmental disorders often manifested by social and behavioral deficiencies. Autonomic dysfunction is frequently reported in the autistic population but the mechanisms remain largely unknown. We aimed to characterize the cardiac autonomic profile of children with autism during a head-up tilt test. Thirty-nine male children were recruited: 19 controls (9.9 ± 1.6 years) and 20 children with ASD without intellectual disability (10.7 ± 1.2 years). Each child underwent a head-up tilt test on a motorized tilt table...
August 9, 2017: Journal of Abnormal Child Psychology
https://www.readbyqxmd.com/read/28717053/pure-autonomic-failure
#15
REVIEW
Thomas P Brown
Pure autonomic failure is a degenerative disorder of the peripheral autonomic nervous system. Patients experience symptomatic hypotension that requires them to sit, squat or lie down to prevent syncope. It is associated with characteristic histopathological findings, resulting in neuronal cytoplasmic inclusions in the peripheral autonomic nerves. These lesions are responsible for defects in the synthesis and release of norepinephrine from sympathetic nerve terminals, resulting in significant hypotension. Patients with autonomic failure also have exaggerated blood pressure responses to common stimuli such as food or fluid intake, heat, exercise and medications...
October 2017: Practical Neurology
https://www.readbyqxmd.com/read/28645449/high-incidence-of-st-t-changes-in-women-during-tilt-table-testing
#16
Prakash Goutham Suryanarayana, Jagdesh Kandala, Frank I Marcus
INTRODUCTION: We have observed electrocardiographic (ECG) changes primarily in women during tilt table testing. METHODS: We reviewed 12 lead ECGs during tilt studies between 2012 and 2016 for changes in ST segments and T waves during tilt table testing. Patients with distinctly abnormal baseline ECGs were excluded. RESULTS: Of the 180 tilt studies, 117 (65%) were in women. There were 32 patients with ECG changes during tilting. Of these, 28 (87...
November 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/28644253/spectrum-of-autonomic-nervous-system-impairment-in-sj%C3%A3-gren-syndrome
#17
Brent P Goodman, Amy Crepeau, Priya S Dhawan, Julie A Khoury, Lucinda A Harris
OBJECTIVE: To describe the spectrum of autonomic dysfunction in a uniformly evaluated cohort of patients with Sjögren syndrome. METHODS: A series of 13 patients underwent a comprehensive evaluation for suspected autonomic impairment, including a neurological examination, autonomic testing, and laboratory studies. A diagnosis of Sjögren syndrome was established as the cause of autonomic dysfunction in all. Clinical features, findings on autonomic testing, and laboratory results are described...
July 2017: Neurologist
https://www.readbyqxmd.com/read/28617840/a-new-test-for-diagnosing-vasovagal-syncope-standing-after-treadmill-test-with-sublingual-nitrate-administration
#18
Tae-Hoon Kim, Ho-Jun Jang, Sihun Kim, Sung Yun Cho, Kyung Sun Song, Christopher Pickett, Heiko J Schmitt, Juyong Lee
INTRODUCTION: Increased adrenergic tone might be an additional trigger of orthostatic stress of vasovagal syncope (VVS). Exercise before standing might provide increased sensitivity compared to standing using a sublingual nitroglycerines protocol during tilt table testing. The aim of this study was to evaluate the diagnostic value of treadmill testing before standing with nitroglycerin administration. METHODS AND RESULTS: A total of 36 patients with syncope or presyncope were enrolled for the test...
2017: PloS One
https://www.readbyqxmd.com/read/28616731/renal-nerve-stimulation-for-treatment-of-neurocardiogenic-syncope-a-review-from-perspective-of-commercialization-potential
#19
REVIEW
B O'Brien, H Zafar, F Sharif
A strong evidence of outcomes for vasovagal syncope is not easily identified. It would seem reasonable that the proposed Mayo Clinic technology would be reserved for cases with severe recurrent or refractory syncope. However, recurrence levels are relatively low, and while some predictive methods have been proposed, recurrence is also influenced by the interaction that occurs during screening and examinations, i.e. recurrence diminishes once an initial diagnosis has been made. Finally, a key factor in being able to identify suitable patients relates to understanding the relative significance of the vasodepression and cardioinhibitory components-the therapy is best suited to patients that have a significant level of both components...
June 14, 2017: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/28585146/deceleration-capacity-a-novel-measure-for-autonomic-nervous-system-in-patients-with-vasovagal-syncope-on-tilt-table-testing
#20
Fen Huang, Chun-Fang Xu, Xiao-Yan Deng, Ping Zuo, Fan Lin, Jing-Jing Fan, Wen-Jia Xu, Xiao-Yun Yang
This study was to investigate the changes of autonomic nerve function and hemodynamics in patients with vasovagal syncope (VVS) during head-up tilt-table testing (HUT). HUT was performed in 68 patients with unexplained syncope and 18 healthy subjects served as control group. According to whether bradycardia, hypotension or both took place during the onset of syncope, the patients were divided during the test into three subgroups: vasodepressor syncope (VD), cardioinhibitory syncope (CI) and mixed syncope (MX) subgroups...
June 2017: Journal of Huazhong University of Science and Technology. Medical Sciences
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