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Neck circumference AND metabolic syndrome OR insulin resistance

Ernesto Maddaloni, Ilaria Cavallari, Mariangela De Pascalis, Hillary Keenan, Kyoungmin Park, Silvia Manfrini, Raffaella Buzzetti, Giuseppe Patti, Germano Di Sciascio, Paolo Pozzilli
Body circumferences have been proposed as potential anthropometric measures for the assessment of cardiometabolic risk as they are independently associated with insulin resistance and diabetes. The aim of this study was to validate neck and wrist circumference and waist-to-hip ratio as practical markers of metabolic dysfunction and atherosclerosis; 120 subjects who underwent coronary angiography and carotid Doppler ultrasound were enrolled in this cross-sectional study. Exclusion criteria were history of diabetes, acute myocardial infarction, body mass index (BMI) <18...
September 15, 2016: American Journal of Cardiology
T Martin-Gimenez, I de Blas, E Aguilera-Tejero, E Diez de Castro, C N Aguirre-Pascasio
Equine metabolic syndrome (EMS) can be diagnosed by hormonal measurements; however, it would be important to find simpler measurements that allow easy identification of affected or at risk individuals. In horses, the dorsal neck region is one of the most frequent anatomical sites for fat deposition and neck obesity has been linked to EMS. The aim of this study was to evaluate the association of hormonal markers of obesity (leptin) and insulin resistance (insulin) with morphometric and ultrasonographic neck measurements in Andalusian horses...
July 2016: Domestic Animal Endocrinology
Yavor Assyov, Antoaneta Gateva, Adelina Tsakova, Zdravko Kamenov
: Purpose/Aim: Neck circumference (NC) is an emerging anthropometric parameter that has been proposed to reflect metabolic health. The aim of the current study was to compare its clinical usefulness to waist circumference (WC) in the assessment of individuals with severe obesity. MATERIALS AND METHODS: A total of 255 subjects participated in the study. All anthropometric measurements were done by a single medical professional. Biochemical measurements included oral glucose-tolerance tests (OGTTs), fasting insulin, lipids, and hepatic enzymes...
April 6, 2016: Endocrine Research
Ana Maria De Bernardi Rodrigues, Cleliani de Cassia da Silva, Ana Carolina Junqueira Vasques, Daniella Fernandes Camilo, Francieli Barreiro, Roberta Soares Lara Cassani, Mariana Porto Zambon, Maria Ângela Reis de Góes Monteiro Antonio, Bruno Geloneze
IMPORTANCE: The association between short sleep duration and decreased insulin sensitivity in adolescents has been described. However, to our knowledge, no studies have investigated this association measuring insulin sensitivity by the hyperglycemic clamp technique. OBJECTIVES: To compare the distributions of parameters of insulin resistance in adolescents with sleep deprivation vs adequate sleep, and to investigate the association between sleep deprivation and insulin sensitivity...
May 1, 2016: JAMA Pediatrics
Zhe Pan, Xianghua Zhuang, Xiaobo Li, Shaoyi Huang, Liang Zhang, Fuchen Lou, Shihong Chen, Yihong Ni
Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a commonly-diagnosed chronic sleep disorder. It is considered to be an important independent risk factor in the development of insulin resistance (IR). Patients with OSAHS exhibit a variety of metabolic disorders, including obesity and metabolic syndrome. Visceral adipose tissue-derived serpin (vaspin) is an adipokine that is considered to be a link between obesity and IR. The present study aimed to evaluate the levels of plasma vaspin in patients with OSAHS and examine their potential correlation with sleep characteristics...
March 2016: Experimental and Therapeutic Medicine
Diego Gomez-Arbelaez, Paul Anthony Camacho, Daniel Dylan Cohen, Sandra Saavedra-Cortes, Cristina Lopez-Lopez, Patricio Lopez-Jaramillo
BACKGROUND: The current study aims to evaluate the association between neck circumference (NC) and several cardio-metabolic risk factors, to compare it with well-established anthropometric indices, and to determine the cut-off point value of NC for predicting children at increased risk of metabolic syndrome, insulin resistance and low-grade systemic inflammation. METHODS: A total of 669 school children, aged 8-14, were recruited. Demographic, clinical, anthropometric and biochemical data from all patients were collected...
March 8, 2016: BMC Pediatrics
Nils Eckstein, Nikolaus Buchmann, Ilja Demuth, Elisabeth Steinhagen-Thiessen, Jivko Nikolov, Dominik Spira, Rahel Eckardt, Kristina Norman
BACKGROUND: Decreased bone mineral density (BMD) has been linked to metabolic disorders, such as type 2 diabetes. However, results regarding the metabolic syndrome (MetS), a cluster of at least 3 of 5 cardiovascular risk parameters with potentially contradictory effects on BMD are still inconclusive. OBJECTIVE: We investigated the effect of MetS and its single parameters on BMD at 3 sites in community-dwelling older subjects. METHODS: 1,402 subjects (51...
2016: Gerontology
Nam H Cho, Tae Jung Oh, Kyoung Min Kim, Sung Hee Choi, Jae Ho Lee, Kyong Soo Park, Hak Chul Jang, Jong Yeol Kim, Hong Kyu Lee, Soo Lim
Neck circumference, a proxy for upper-body fat, may be a unique fat depot that indicates metabolic risk beyond whole body fat. We investigated whether neck circumference is associated with development of diabetes mellitus (DM) in a subset of data with Korean Genome and Epidemiology Study (n = 3521, age range = 42-71 years). Nondiabetic subjects at the baseline were categorized into 4 groups (Q1-Q4) according to their neck circumference. Parameters related with β-cell function and insulin resistance including Epworth sleepiness scale and snoring habit were examined...
2015: Scientific Reports
Luciene da Silva Araújo, Julia Freitas Rodrigues Fernandes, Márcia Regina Simas Torres Klein, Antonio Felipe Sanjuliani
OBJECTIVES: Obstructive sleep apnea (OSA) is associated with an increased risk of cardiovascular disease (CVD). Several of the proposed mechanisms for the development of CVD in OSA are similar to those proposed for the increased risk of CVD in obesity, so that it is difficult to determine the influence of OSA on these pathogenic mechanisms in obese individuals. The aim of this study was to evaluate the relationship of OSA with endothelial function, oxidative stress, inflammatory biomarkers, metabolic profile, sympathetic nervous system activity, and blood pressure (BP) in obese individuals...
November 2015: Nutrition
E Kienzle, J Fritz
Nutrition-induced laminitis is often caused by i) fermentation of large amounts of carbohydrates in the hindgut (usually fructans from grass or starch from cereals), which cause the release and absorption of microbial toxins and ii) insulin resistance induced by being overweight (equine metabolic syndrome). Both causes can act together. Overweight horses with a history of laminitis need to reduce body weight to prevent further incidences of laminitis. Weight reduction occurs normally on a diet of late-cut hay, a hay-straw mixture (maximally one third straw to prevent constipation) or grass seed straw all at 1-1...
2013: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
D Weghuber, S Zelzer, I Stelzer, K Paulmichl, D Kammerhofer, W Schnedl, D Molnar, H Mangge
BACKGROUND: Since obesity and its associated co-morbidities do not only have effect on the individual patient, but also on society and the health system, it is of great importance to investigate this lifestyle-disease. The rationale of this study was to distinguish metabolically healthy from unhealthy overweight/obese patients as compared to healthy normal weight children and adolescents by means of a comprehensive anthropometric, laboratory and sonomorphological vascular assessment. MATERIALS AND METHODS: 299 study participants were derived from the prospective, observational study STYJOBS/EDECTA (STYrian Juvenile Obesity Study/Early DEteCTion of Arteriosclerosis)...
July 2013: Experimental and Clinical Endocrinology & Diabetes
Christiane Stabe, Ana Carolina Junqueira Vasques, Marcelo Miranda Oliveira Lima, Marcos Antonio Tambascia, Jose Carlos Pareja, Ademar Yamanaka, Bruno Geloneze
OBJECTIVE: To investigate the relationship of the neck circumference (NC) with the metabolic syndrome (MetS) and insulin resistance (IR) in a large Brazilian population-based sample, within a wide range of adiposity and glucose tolerance, and to establish cut-off values of the NC for MetS and IR. CONTEXT: The NC correlates with cardiovascular risk factors, IR and components of MetS. Upper-body subcutaneous (sc) fat, as estimated by the NC, is associated with cardiovascular risk factors as much as abdominal fat, which is usually estimated by the waist circumference (WC)...
June 2013: Clinical Endocrinology
Maria R Bonsignore, Cristina Esquinas, Antonia Barceló, Manuel Sanchez-de-la-Torre, Alessandra Paternó, Joaquin Duran-Cantolla, José M Marín, Ferran Barbé
The metabolic syndrome shows a variable prevalence in obstructive sleep apnoea (OSA), and its association with insulin resistance or excessive daytime sleepiness in OSA is unclear. This study assessed the following in consecutive patients with newly diagnosed OSA: 1) the prevalence of metabolic syndrome; and 2) its association with insulin resistance and daytime sleepiness. Metabolic syndrome (National Cholesterol Education Program Adult Treatment Panel (NCEP-ATP) III criteria), insulin resistance (Homeostatic Model Assessment (HOMA) index, n = 288) and daytime sleepiness (Epworth Sleepiness Scale) were assessed in 529 OSA patients...
May 2012: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
Omar S El Safoury, Rania M Abdel Hay, Marwa M Fawzy, Dina Kadry, Iman M Amin, Ola M Abu Zeid, Laila A Rashed
BACKGROUND: Skin tags (STs), are papillomas commonly found in the neck and in the axillae of middle-aged and elderly people. Metabolic syndrome (MS) is a complex of interrelated risk factors for cardiovascular disease and diabetes. Epidemiologic studies of different ethnic populations have indicated that hyperleptinaemia and leptin resistance are strongly associated with MS. AIM: To study the possible relation of skin tags and leptin levels to MS guided by the International Diabetes Federation (IDF) diagnostic criteria...
September 2011: Indian Journal of Dermatology, Venereology and Leprology
Altan Onat, Gülay Hergenç, Hüsniye Yüksel, Günay Can, Erkan Ayhan, Zekeriya Kaya, Dursun Dursunoğlu
BACKGROUND & AIMS: To investigate the relationship of neck circumference (NC) to metabolic syndrome (MetS) and obstructive sleep apnea syndrome (OSAS) and whether it adds information to that provided by waist circumference. METHODS: Cross-sectional analysis of a population sample of 1,912 men and women, aged 55.1 +/- 12 years, representative of Turkish adults. MetS was identified based on modified criteria of the ATP-III, OSAS when habitual snoring and episodes of apnea were combined with another relevant symptom...
February 2009: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
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