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https://www.readbyqxmd.com/read/28635141/high-sensitivity-non-invasive-detection-of-calcifications-deep-inside-biological-tissue-using-transmission-raman-spectroscopy
#1
Adrian Ghita, Pavel Matousek, Nick Stone
The aim of this research was to develop a novel approach to probe non-invasively the composition of inorganic chemicals buried deep in large volume biological samples. The method is based on advanced Transmission Raman Spectroscopy (TRS) permitting chemical specific detection within a large sampling volume. The approach could be beneficial to chemical identification of the breast calcifications detected during mammographic X-ray procedures. The chemical composition of a breast calcification reflects the pathology of the surrounding tissue, malignant or benign and potentially the grade of malignancy...
June 21, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28632500/photon-detection-efficiency-of-laboratory-based-x-ray-phase-contrast-imaging-techniques-for-mammography-a-monte-carlo-study
#2
Somayeh Saghamanesh, Seyed Mohammad Reza Aghamiri, Alireza Kamali-Asl, Wataru Yashiro
An important challenge in real-world biomedical applications of X-ray phase contrast imaging (XPCI) techniques is the efficient use of the photon flux generated by an incoherent and polychromatic X-ray source. This efficiency can directly influence dose and exposure time and ideally should not affect the superior contrast and sensitivity of XPCI. In this paper, we present a quantitative evaluation of the photon detection efficiency of two laboratory-based XPCI methods, grating interferometry (GI) and coded-aperture (CA)...
June 20, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28630886/review-of-the-current-status-of-radiation-protection-in-diagnostic-radiology-in-africa
#3
REVIEW
Wilbroad Muhogora, Madan M Rehani
The aim of this paper is to review the available published studies from African countries on patient doses and medical radiation protection and identify strengths, weaknesses, and challenges. Papers on radiation doses to patients published until 2016 pertaining to studies in African countries were reviewed. Radiography, interventional radiology, computed tomography (CT), and mammography modalities were covered. In radiography, the entrance surface air kerma values were below the established diagnostic reference levels (DRLs) provided by the International Atomic Energy Agency, European Commission, and National Council on Radiation Protection and Measurements...
July 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28630214/patient-derived-interstitial-fluids-and-predisposition-to-aggressive-sporadic-breast-cancer-through-collagen-remodeling-and-inactivation-of-p53
#4
Timothy Kenny, Hank Schmidt, Kerin Adelson, Yujin Hoshida, Anna P Koh, Nagma Shah, John P Mandeli, Jess Ting, Doris Germain
Despite the fact that interstitial fluid (IF) represents a third of our body fluid, it is the most poorly understood body fluid in medicine. Increased IF pressure is thought to result from the increased deposition of extracellular matrix in the affected tissue preventing its reabsorption. In the cancer field, increased rigidity surrounding a cancerous mass remains the main reason that palpation and radiological examination, such as mammography, are used for cancer detection. While the pressure produced by IF has been considered, the biochemical composition of IF has not been considered in its effect on tumors...
June 19, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28629329/personalised-informed-choice-on-evidence-and-controversy-on-mammography-screening-study-protocol-for-a-randomized-controlled-trial
#5
Anna Roberto, Cinzia Colombo, Giulia Candiani, Livia Giordano, Paola Mantellini, Eugenio Paci, Roberto Satolli, Mario Valenza, Paola Mosconi
BACKGROUND: In Italy women aged 50-69 are invited for a population-based breast cancer (BC) screening. Physicians, policy makers and patients associations agree on the need to inform women about the benefits and harms in order to permit an informed decision. Decision aids (DA) are an effective way to support people in their decisions about health. This trial aims to assess women's informed choices, according to their health literacy and values, on participating or not in BC screening for the first time...
June 19, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28628656/ultrasound-guided-cable-free-13-gauge-vacuum-assisted-biopsy-of-non-mass-breast-lesions
#6
Jiwoon Seo, Sun Mi Kim, Mijung Jang, Bo La Yun, Soo Hyun Lee, Eun-Kyu Kim, Eunyoung Kang, So Yeon Park, Woo Kyung Moon, Hye Young Choi, Bohyoung Kim
PURPOSE: To compare the outcomes of ultrasound-guided core biopsy for non-mass breast lesions by the novel 13-gauge cable-free vacuum-assisted biopsy (VAB) and by the conventional 14-gauge semi-automated core needle biopsy (CCNB). MATERIALS AND METHODS: Our institutional review board approved this prospective study, and all patients provided written informed consent. Among 1840 ultrasound-guided percutaneous biopsies performed from August 2013 to December 2014, 145 non-mass breast lesions with suspicious microcalcifications on mammography or corresponding magnetic resonance imaging finding were subjected to 13-gauge VAB or 14-gauge CCNB...
2017: PloS One
https://www.readbyqxmd.com/read/28627297/a-bayesian-simulation-model-for-breast-cancer-screening-incidence-treatment-and-mortality
#7
Xuelin Huang, Yisheng Li, Juhee Song, Donald A Berry
BACKGROUND: The important but complicated research questions regarding the optimization of mammography screening for the detection of breast cancer are unable to be answered through any single trial or a simple meta-analysis of related trials. The Cancer Intervention and Surveillance Network (CISNET) breast groups provide answers using complex statistical models to simulate population dynamics. Among them, the MD Anderson Cancer Center (Model M) takes a unique approach by not making any assumptions on the natural history of breast cancer, such as the distribution of the indolent time before detection, but simulating only the observable part of a woman's disease and life...
June 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28624977/interaction-of-mammographic-breast-density-with-menopausal-status-and-postmenopausal-hormone-use-in-relation-to-the-risk-of-aggressive-breast-cancer-subtypes
#8
Lusine Yaghjyan, Rulla M Tamimi, Kimberly A Bertrand, Christopher G Scott, Matthew R Jensen, V Shane Pankratz, Kathy Brandt, Daniel Visscher, Aaron Norman, Fergus Couch, John Shepherd, Bo Fan, Yunn-Yi Chen, Lin Ma, Andrew H Beck, Steven R Cummings, Karla Kerlikowske, Celine M Vachon
PURPOSE: We examined the associations of mammographic breast density with breast cancer risk by tumor aggressiveness and by menopausal status and current postmenopausal hormone therapy. METHODS: This study included 2596 invasive breast cancer cases and 4059 controls selected from participants of four nested case-control studies within four established cohorts: the Mayo Mammography Health Study, the Nurses' Health Study, Nurses' Health Study II, and San Francisco Mammography Registry...
June 17, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28621548/an-investigation-into-the-mammographic-appearances-of-missed-breast-cancers-when-recall-rates-are-reduced
#9
Norhashimah Mohd Norsuddin, Claudia Mello-Thoms, Warren Reed, Mary Rickard, Sarah Lewis
OBJECTIVES: This study investigated whether certain mammographic appearances of breast cancer are missed when radiologists read at lower recall rates. METHODS: Five radiologists read one identical test set of 200 mammographic (180 normal cases and 20 abnormal cases) three times and were requested to adhere to three different recall rate conditions: free recall, 15% and 10%. The radiologists were asked to mark the locations of suspicious lesions and provide a confidence rating for each decision...
June 16, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28619739/renal-cell-carcinoma-with-isolated-breast-metastasis
#10
Sarah M Dhannoon, Ali A Alsaad, Abdo R Asmar, Fuad H Shahin
Renal cell carcinoma (RCC) is a highly prevalent disease worldwide with many cases being metastasised to various organs during the time of initial presentation. Metastatic RCC to the breast is a rare entity and can mimic primary breast carcinoma. In this article, we present a 63-year-old Caucasian woman presented with a breast mass that was detected by screening mammography and found to have a biopsy proven grade-II clear RCC in the breast tissue. Despite the high incidence and prevalence of primary breast cancer, metastasis from extramammary should be suspected in patients with a prior history of other cancers...
June 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28618754/evaluation-and-comparison-of-radiologic-pathologic-findings-in-invasive-cribriform-carcinoma-of-the-breast
#11
Pınar Balci, Işıl Başara Akin, Nevin Köremezli, Merih Güray Durak, Canan Altay, Naciye Sinem Gezer, Ali İbrahim Sevinç
BACKGROUND/AIM: This study aimed to report invasive cribriform carcinoma (ICC) with radiological and histopathologic correlations. MATERIALS AND METHODS: Seventy patients with ICC were classified into two groups; pure ICC patients and patients with >50% cribriform carcinoma component were included in group 1, while patients with <50% cribriform carcinoma component were included in group 2. All patients were reviewed according to American College of Radiology (ACR) breast imaging reporting and data system (BI-RADS) lexicon of mammography (MG), ultrasonography (US), and magnetic resonance imaging (MRI)...
June 12, 2017: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28617264/the-professional-quality-criteria-of-italian-breast-screening-radiologists-results-from-a-national-survey-comparing-the-programmes-started-in-2000-2012-versus-the-ones-started-in-1990-1999
#12
Doralba Morrone, Livia Giordano, Franca Artuso, Daniela Bernardi, Chiara Fedato, Alfonso Frigerio, Daniela Giorgi, Carlo Naldoni, Gianni Saguatti, Daniela Severi, Mario Taffurelli, Daniela Terribile, Leonardo Ventura, Lauro Bucchi
INTRODUCTION: In Italy, due to increasing healthcare budget and staff shortages, the recently created regional mammography screening programmes were established under worse radiology practice quality criteria than the previously created programmes. METHODS: Using available data from a national questionnaire survey conducted at the end of 2013 and involving 222 responder radiologists, we compared the main professional quality standards of radiologists working in the screening programmes established during the period 2000-2012 with those working in the screening programmes created from 1990 to 1999...
April 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28615408/examining-screening-mammography-participation-among-women-aged-40-to-74
#13
Karena D Volesky, Paul J Villeneuve
OBJECTIVE: To examine participation in screening mammography among women aged 40 to 74 and identify which factors are associated with those women who participate in screening. DESIGN: Secondary analysis of the cross-sectional 2012 Canadian Community Health Survey. SETTING: Canada. PARTICIPANTS: A population-based national sample of 18 312 women aged 40 to 74. MAIN OUTCOME MEASURES: Women's participation in screening mammography in the 2 years preceding the 2012 Canadian Community Health Survey; women's preventive health activities (ie, having a regular doctor, a recent physical checkup, and a Papanicolaou test), which were adjusted for sociodemographic factors...
June 2017: Canadian Family Physician Médecin de Famille Canadien
https://www.readbyqxmd.com/read/28614990/screening-organization-and-recall-rate-in-a-regional-breast-screening-programme
#14
Tina Beruchashwili, Rema Gvamichava, Stephen W Duffy
Objective To use results on recall rates from a regional non-population-based breast screening programme to inform practice in a planned national population-based programme. Methods We analysed data on rates of recall for further assessment in 27,327 mammographic screening episodes in 2015-2016 in the breast screening programme in the city of Tbilisi, Georgia. Screening was done by two-view digital mammography with double reading in women aged 40-70, and further assessment took place at the same clinic and during the same visit as the initial screening mammogram...
January 1, 2017: Journal of Medical Screening
https://www.readbyqxmd.com/read/28612666/igg4-related-sclerosing-disease-of-the-breast-in-a-male-patient
#15
Taisia Vitkovski, Galina S Marder, Dominic A Filardi, Ekta Gupta, Frank Breuer
IgG4-related sclerosing disease of the breast is a rare entity with 10 reports in the literature. We report the first case in a male patient. A 48-year-old male presented with 4-week history of palpable right upper outer quadrant breast mass associated with skin puckering. He reported a family history of breast cancer in his aunt. Ultrasound and mammography showed a spiculated 2.5-cm mass associated with skin retraction with extension to the pectoralis muscle. Ultrasound-guided core biopsy was performed. The findings were interpreted as acute and chronic inflammatory process...
June 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28612356/assessing-the-influence-of-rater-and-subject-characteristics-on-measures-of-agreement-for-ordinal-ratings
#16
Kerrie P Nelson, Aya A Mitani, Don Edwards
Widespread inconsistencies are commonly observed between physicians' ordinal classifications in screening tests results such as mammography. These discrepancies have motivated large-scale agreement studies where many raters contribute ratings. The primary goal of these studies is to identify factors related to physicians and patients' test results, which may lead to stronger consistency between raters' classifications. While ordered categorical scales are frequently used to classify screening test results, very few statistical approaches exist to model agreement between multiple raters...
June 13, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28612325/stages-of-change-for-mammography-among-mexican-women-and-a-decisional-balance-comparison-across-countries
#17
Ana María Salinas-Martínez, David Emmanuel Castañeda-Vásquez, Norma Guadalupe García-Morales, Norma Edith Oliva-Sosa, Laura Hermila de-la-Garza-Salinas, Georgina Mayela Núñez-Rocha, José Manuel Ramírez-Aranda
An analysis of the adoption of secondary preventive behaviors is significant in regions with disparities in mammography use and breast cancer survival. Therefore, we determined the cognitive factors and the degree to which they differentiate stages of change in mammography among Mexican women. We also compared the decisional balance performance at Mexico, Switzerland, South Korea, and the USA. A cross-sectional study was designed for women in the stages of precontemplation (n = 240), contemplation (n = 243), action (n = 205), maintenance (n = 311), and relapse (n = 348)...
June 14, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28611851/acceleration-of-image-segmentation-algorithm-for-breast-mammogram-images-using-high-performance-reconfigurable-dataflow-computers
#18
Ivan L Milankovic, Nikola V Mijailovic, Nenad D Filipovic, Aleksandar S Peulic
Image segmentation is one of the most common procedures in medical imaging applications. It is also a very important task in breast cancer detection. Breast cancer detection procedure based on mammography can be divided into several stages. The first stage is the extraction of the region of interest from a breast image, followed by the identification of suspicious mass regions, their classification, and comparison with the existing image database. It is often the case that already existing image databases have large sets of data whose processing requires a lot of time, and thus the acceleration of each of the processing stages in breast cancer detection is a very important issue...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28610472/incidental-breast-carcinoma-in-reduction-mammoplasty
#19
Michaël Huysmans, Marc Bronckaers, Charlotte Schillebeeckx, Dirk Servaes
AIM: The objective of this study was to analyze the incidence and treatment options of occult cancer or atypical lesions found in the histopathological examination of reduction mammoplasty (RM) specimens. The role of preoperative mammography and systematic histopathological examination are discussed. METHODS: We performed a retrospective single-center database review of all patients who underwent a RM between January 2005 and December 2014. Preoperative examination, histopathological findings and follow-up were documented...
June 13, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28609204/surveillance-of-women-with-the-brca1-or-brca2-mutation-by-using-biannual-automated-breast-us-mr-imaging-and-mammography
#20
Jan C M van Zelst, Roel D M Mus, Gwendolyn Woldringh, Matthieu J C M Rutten, Peter Bult, Suzan Vreemann, Mathijn de Jong, Nico Karssemeijer, Nicoline Hoogerbrugge, Ritse M Mann
Purpose To evaluate a multimodal surveillance regimen including yearly full-field digital (FFD) mammography, dynamic contrast agent-enhanced (DCE) magnetic resonance (MR) imaging, and biannual automated breast (AB) ultrasonography (US) in women with BRCA1 and BRCA2 mutations. Materials and Methods This prospective multicenter trial enrolled 296 carriers of the BRCA mutation (153 BRCA1 and 128 BRCA2 carriers, and 15 women with first-degree untested relatives) between September 2010 and November 2012, with follow-up until November 2015...
June 13, 2017: Radiology
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