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https://www.readbyqxmd.com/read/28345114/peripheral-endothelial-function-after-arterial-switch-operation-for-d-looped-transposition-of-the-great-arteries
#1
Heather Y Sun, Katie Jo Stauffer, Susan E Nourse, Chau Vu, Elif Seda Selamet Tierney
Coronary artery re-implantation during arterial switch operation in patients with D-looped transposition of the great arteries (D-TGA) can alter coronary arterial flow and increase shear stress, leading to local endothelial dysfunction, although prior studies have conflicting results. Endothelial pulse amplitude testing can predict coronary endothelial dysfunction by peripheral arterial testing. This study tested if, compared to healthy controls, patients with D-TGA after arterial switch operation had peripheral endothelial dysfunction...
March 27, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28342332/steady-state-and-dynamic-behaviors-of-a-methane-biofilter-under-periodic-addition-of-ethanol-vapors
#2
Milad Ferdowsi, Antonio Avalos Ramirez, J Peter Jones, Michèle Heitz
Ethanol was added to a methane (CH4) biofilter with inorganic packing materials over three cycles based on increasing the gas flow rates from 3 to 6 and finally to 12 L min(-1) corresponding to empty bed residence times (EBRT) of 6, 3 and 1.5 min. The steady state performance of the CH4 biofilter was studied for CH4 inlet loads (ILs) of 33, 66 and 132 gCH4 m(-3) h(-1) prior and after each ethanol cycle. In addition, the steady state removal of a mixture of CH4 and ethanol for a CH4/ethanol mass ratio of around 7...
March 22, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28341988/unexpected-differences-between-planar-and-column-liquid-chromatographic-retention-of-1-acenaphthenol-enantiomers-controlled-by-supramolecular-interactions-involving-%C3%AE-cyclodextrin-at-subambient-temperatures
#3
Hatsuichi Ohta, Elżbieta Włodarczyk, Krzysztof Piaskowski, Aleksandra Kaleniecka, Lucyna Lewandowska, Michał J Baran, Mariusz Wojnicz, Kiyokatsu Jinno, Yoshihiro Saito, Paweł K Zarzycki
We report the results of experimental work focusing on host-guest supramolecular complex creation between macrocyclic compound (β-cyclodextrin) and 1-acenaphthenol enantiomers (racemic mixture) in liquid phase composed of 35% acetonitrile in water (v/v) at different temperatures ranging from 0 to 90 °C. Experimental setup involved several analytical protocols based on classical non-forced flow planar chromatography (RP-18 TLC plates), micro-TLC (RP-18 W HPTLC plates), column chromatography (HPLC with C-18 and C-30 stationary phases), as well as UV-Vis spectrophotometry and optical microscopy...
March 24, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28341826/poly-ethylmethacrylate-co-diethylaminoethyl-acrylate-coating-improves-endothelial-re-population-bio-mechanical-and-anti-thrombogenic-properties-of-decellularized-carotid-arteries-for-blood-vessel-replacement
#4
Elena López-Ruiz, Seshasailam Venkateswaran, Macarena Perán, Gema Jiménez, Salvatore Pernagallo, Juan J Díaz-Mochón, Olga Tura-Ceide, Francisco Arrebola, Juan Melchor, Juan Soto, Guillermo Rus, Pedro J Real, María Diaz-Ricart, Antonio Conde-González, Mark Bradley, Juan A Marchal
Decellularized vascular scaffolds are promising materials for vessel replacements. However, despite the natural origin of decellularized vessels, issues such as biomechanical incompatibility, immunogenicity risks and the hazards of thrombus formation, still need to be addressed. In this study, we coated decellularized vessels obtained from porcine carotid arteries with poly (ethylmethacrylate-co-diethylaminoethylacrylate) (8g7) with the purpose of improving endothelial coverage and minimizing platelet attachment while enhancing the mechanical properties of the decellularized vascular scaffolds...
March 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28341290/the-cessation-of-breathing-in-the-chicken-embryo-during-cold-hypometabolism
#5
Ryoji Ide, Satoko Tomita Ide, Jacopo P Mortola
The avian embryo toward end-incubation combines gas exchange through the chorioallantoic membrane (CAM) and pulmonary ventilation (V˙E). The main experiments examined breathing activity during cold-hypometabolism. Chicken embryos close to hatching were prepared for simultaneous measurements of oxygen consumption ( [Formula: see text] ) and carbon dioxide production ( [Formula: see text] ; open-flow methodology) and breathing frequency (f; barometric technique). As ambient (Ta) and egg temperature (Tegg) dropped, breathing eventually ceased at ∼18°C, when [Formula: see text] and [Formula: see text] were 22-28% of the normothermic values...
March 21, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28339633/osmotic-indices-and-kidney-concentrating-activity-population-based-data-on-correlates-and-prognostic-power
#6
Massimo Cirillo, Giancarlo Bilancio, Cinzia Lombardi, Pierpaolo Cavallo, Oscar Terradura Vagnarelli, Alberto Zanchetti, Martino Laurenzi
Background.: Research data are limited on indices of osmotic equilibrium and of kidney concentrating activity (KCA). This study investigated correlates and prognostic power of these indices in a sample of the general population. Methods.: Urine osmolality (U-osm), plasma osmolality (P-osm), plasma creatinine and other variables were measured by the Gubbio Study for the 1988-92 exam (baseline). Plasma creatinine and other variables were re-measured in the 2001-07 exam (follow-up)...
February 4, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28339567/role-of-biomechanical-forces-in-hyperfiltration-mediated-glomerular-injury-in-congenital-anomalies-of-the-kidney-and-urinary-tract
#7
Tarak Srivastava, Ganesh Thiagarajan, Uri S Alon, Ram Sharma, Ashraf El-Meanawy, Ellen T McCarthy, Virginia J Savin, Mukut Sharma
Congenital anomalies of the kidney and urinary tract (CAKUT) including solitary kidney constitute the main cause of progressive chronic kidney disease (CKD) in children. Children born with CAKUT develop signs of CKD only during adolescence and do not respond to renin-angiotensin-aldosterone system blockers. Early cellular changes underlying CKD progression to end-stage renal disease by early adulthood are not well understood. The mechanism of maladaptive hyperfiltration that occurs from loss of functional nephrons, including solitary kidney, is not clear...
January 17, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28338117/endovascular-treatment-for-acute-mesenteric-ischaemia-in-a-young-woman-with-polyarterial-disease
#8
Mihai C Ober, Calin Homorodean, Dan A Tataru, Antonia E Macarie, Camelia D Ober, Dan M Olinic
BACKGROUND: Acute mesenteric ischaemia is a condition with a grim prognosis on conservative treatment. Endovascular revascularisation is a promising approach for some of these patients. CASE REPORT: We present the case of a 44-year-old woman with a history of severe arterial hypertension, left leg claudication, and overlooked symptoms of chronic mesenteric ischaemia for one year, who was admitted for severe abdominal pain for one week. Computed tomographic angiography (CTA) showed acute mesenteric ischaemia by occlusion of the coeliac trunk and the superior mesenteric artery (SMA), without bowel perforation...
March 2017: Journal of Gastrointestinal and Liver Diseases: JGLD
https://www.readbyqxmd.com/read/28337914/electrically-actuated-valves-for-woven-fabric-lateral-flow-devices
#9
Tanya Narahari, Dhananjaya Dendukuri, Shashi K Murthy
The integration of flow control elements into low-cost biosensors, presents a significant engineering challenge. This article describes the development and integration of active, chemical valves into lateral flow devices, using a scalable, single-step, weaving-based manufacturing approach. The valve was constructed from an electrically conductive polymer, polypyrrole. The polymer switches between wetting and non-wetting states when it is reduced and oxidized via the application of an electrochemical potential...
March 24, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28332508/prolactin-as-a-predictor-of-endothelial-dysfunction-and-arterial-stiffness-progression-in-menopause
#10
G Georgiopoulos, I Lambrinoudaki, F Athanasouli, E Armeni, A Koliviras, A Augoulea, D Rizos, C Papamichael, A Protogerou, K Stellos, K Stamatelopoulos
Postmenopausal women are at increased risk for progression of arteriosclerosis and hypertension. Recent cross-sectional evidence suggests that high normal circulating prolactin levels may accelerate vascular ageing in menopause. Postmenopausal women (n=201) were consecutively recruited from a Menopause Clinic and re-evaluated in at least one follow-up visit within the next 3 years. Baseline circulating prolactin levels were measured while both baseline and follow-up vascular and biochemical measurements were performed...
March 23, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28328147/effect-of-needle-diameter-on-the-viability-of-equine-bone-marrow-derived-mesenchymal-stem-cells
#11
Hayley M Lang, Lauren V Schnabel, Jennifer M Cassano, Lisa A Fortier
OBJECTIVES: Mesenchymal stem cells (MSCs) are frequently delivered via needle injection for treatment of musculoskeletal injuries. The purpose of this study was to evaluate the effect of needle diameter on the viability of MSCs. METHODS: Equine bone marrow-derived MSCs from 5 horses were suspended in PBS, and held at room temperature for 7 hours to mimic shipping conditions. Two replicate samples for each needle size (20, 22, 23, or 25-gauge [ga]) were aspirated into a 3 mL syringe and re-injected into the holding vial 3 times, to reproduce the resuspension of cells prior to injection in clinical cases...
March 22, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28323210/the-protective-activity-of-mesothelial-cells-against-peritoneal-growth-of-gastrointestinal-tumors-the-role-of-soluble-icam-1
#12
Justyna Mikuła-Pietrasik, Paweł Uruski, Małgorzata Kucińska, Andrzej Tykarski, Krzysztof Książek
In this project we examined how the presence of human peritoneal mesothelial cells (HPMCs) modifies (supports or inhibits) colorectal and pancreatic cancer cell progression in mice peritoneal cavity. Experiments were performed using primary, omentum-derived HPMCs, commercially available colorectal (SW-480) and pancreatic (PSN-1) cancer cells, and immunocompromised SCID mice. Tumor growth within the peritoneal cavity was monitored using bioluminescence. Adhesion of the cancer cells to HPMCs was examined using a fluorescence-based method, while the incidence of apoptosis was quantified using flow cytometry...
March 18, 2017: International Journal of Biochemistry & Cell Biology
https://www.readbyqxmd.com/read/28323191/the-feasibility-and-safety-of-separate-carotid-artery-stenting-using-the-restrict-protective-method-for-bilateral-carotid-stenosis
#13
Tomotaka Ohshima, Ishu Bishnori, Kojiro Ishikawa, Shunsaku Goto, Taiki Yamamoto, Yoko Kato
BACKGROUND: and Purpose: The treatment strategy for bilateral carotid stenosis (BCS) is not clear. We report our experience of treating 12 patients with BCS using separate carotid artery stenting (CAS) using the restrict protective method. The order of treatment site and the protective method are also discussed. MATERIALS AND METHODS: Between April 2012 and November 2016, 24 lesions in 12 patients (range, 44-83 years; mean, 71 years; 1 woman) underwent CAS at Kariya Toyota General Hospital...
March 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28317442/application-of-response-surface-methodology-and-semi-mechanistic-model-to-optimize-fluoride-removal-using-crushed-concrete-in-a-fixed-bed-column
#14
Bon-Wun Gu, Chang-Gu Lee, Seong-Jik Park
The aim of this study was to investigate the removal of fluoride from aqueous solutions by using crushed concrete fines (CCF) as a filter medium. Column experiments were performed in step injection mode under varying conditions of influent solution including pH 3-7, flow rate of 0.3-0.7 mL/min, and filter depth of 10-20 cm. The performance of fixed-bed columns was evaluated on the basis of the removal ratio (Re), uptake capacity (qe), degree of sorbent used (DoSU), and sorbent usage rate (SUR) obtained from breakthrough curves (BTC)...
March 18, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28316865/treatment-of-intracranial-aneurysms-with-flow-re-direction-endoluminal-device-a-single-centre-experience-with-short-term-follow-up-results
#15
Neeraj Ramesh Mahboobani, Wing Ho Chong, Samuel Siu Kei Lam, Jimmy Chi Wai Siu, Chong Boon Tan, Yiu Chung Wong
PURPOSE: A flow diverter (FD) is an effective treatment option for intracranial aneurysms. The Flow Re-direction Endoluminal Device (FRED) is a relatively new flow diverter with a unique dual-layer design. We report our experience and short-term results with the FRED. MATERIALS AND METHODS: We did a retrospective review of all consecutive cases in which the FRED was used to treat intracranial aneurysms at a single institution from March 2014 till December 2015. Clinical parameters, aneurysm characteristics, technical results and short-term outcomes were reviewed...
March 2017: Neurointervention
https://www.readbyqxmd.com/read/28304190/the-second-generation-eclips-endovascular-clip-system-initial-experience
#16
Albert H Chiu, Joost De Vries, Cian J O'Kelly, Howard Riina, Ian McDougall, Jonathan Tippett, Martina Wan, Airton Leonardo de Oliveira Manoel, Thomas R Marotta
OBJECTIVE Treatment of wide-necked intracranial aneurysms is associated with higher recanalization and complication rates; however, the most commonly used methods are not specifically designed to work in bifurcation lesions. To address these issues, the authors describe the evolution in the design and use of the eCLIPs (Endovascular Clip System) device, a novel hybrid stent-like assist device with flow diverter properties that was first described in 2008. METHODS A registry was established covering 13 international centers at which patients were treated with the second-generation eCLIPs device...
March 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28293871/greenlight-laser-photoselective-vaporization-of-the-prostate-for-treatment-of-benign-prostate-hyperplasia-lower-urinary-tract-symptoms-in-patients-with-different-post-void-residual-urine
#17
Fei Luo, Hong-Hong Sun, Yan-Hui Su, Zhi-Hua Zhang, Ya-Shen Wang, Zhen Zhao, Jian Li
The purpose of this study is to assess the safety and efficacy of GreenLight laser photoselective vaporization of the prostate (PVP) for the treatment of benign prostate hyperplasia/lower urinary tract symptoms (BPH/LUTS) in patients with different post-void residual urine (PVR). BPH/LUTS patients treated with PVP from January 2014 to January 2016 were enrolled in the present study. All patients were divided into PVR > 50, 50 ≤ PVR < 400, and PVR ≥ 400 ml groups, and standard general and urological methods for BPH/LUTS were carried out...
March 14, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28289849/geo-helminthiasis-among-migrants-in-sicily-a-possible-focus-for-re-emerging-neurocysticercosis-in-europe
#18
Ildebrando Patamia, Piermario Nicotra, Davide Amodeo, Loretta Giuliano, Calogero Edoardo Cicero, Alessandra Nicoletti
A dramatic increasing immigration flow was recorded in Europe during the last years. Only in Sicily 120,239 people arrived in 2014. Immigrants may carry neglected tropical diseases endemic in their origin countries. The aim of our study was to evaluate the frequency of geo-helminthiasis, and in particular of intestinal taeniasis, in a sample of migrants hosted in a large asylum seeker centre in the province of Catania. A stool sample was obtained from all the enrolled subjects and a coproparasitological examination was performed...
March 13, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28284381/mechanisms-of-drug-induced-interstitial-nephritis
#19
REVIEW
Rajeev Raghavan, Saed Shawar
Drug-induced acute interstitial nephritis (DI-AIN) is a drug hypersensitivity reaction (DHR) that manifests 7 to 10 days after exposure to the culprit drug. DHRs account for fewer than 15% of reported adverse drug reactions. The kidneys are susceptible to DHR because: (1) the high renal blood flow whereby antigens are filtered, secreted, or concentrated, and (2) it is a major site of excretion for drugs and drug metabolites. More than 250 different drugs from various classes have been incriminated as causative agents of DI-AIN, the third most common cause of acute kidney injury in the hospital...
March 2017: Advances in Chronic Kidney Disease
https://www.readbyqxmd.com/read/28284079/label-free-identification-of-activated-t-lymphocytes-through-tridimensional-microsensors-on-chip
#20
Enrica Rollo, Enrico Tenaglia, Raphaël Genolet, Elena Bianchi, Alexandre Harari, George Coukos, Carlotta Guiducci
Label-free approaches to assess cell properties ideally suit the requirements of cell-based therapeutics, since they permit to characterize cells with minimal perturbation and manipulation, at the benefit of sample recovery and re-employment for treatment. For this reason, label-free techniques would find sensible application in adoptive T cell-based immunotherapy. In this work, we describe the label-free and single-cell detection of in vitro activated T lymphocytes in flow through an electrical impedance-based setup...
March 3, 2017: Biosensors & Bioelectronics
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