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https://www.readbyqxmd.com/read/28429762/annealing-induced-re-crystallization-in-ch3nh3pbi3-xclx-for-high-performance-perovskite-solar-cells
#1
Yingguo Yang, Shanglei Feng, Meng Li, Weidong Xu, Guangzhi Yin, Zhaokui Wang, Baoquan Sun, Xingyu Gao
Using poly(3,4-ethylenedioxythiophene):polystyrene sulfonate (PEDOT:PSS) as hole conductor, a series of inverted planar CH3NH3PbI3-xClx perovskite solar cells (PSCs) were fabricated based on perovskite annealed by an improved time-temperature dependent (TTD) procedure in a flowing nitrogen atmosphere for different time. Only after an optimum annealing time, an optimized power conversion efficiency of 14.36% could be achieved. To understand their performance dependence on annealing time, an in situ real-time synchrotron-based grazing incidence X-ray diffraction (GIXRD) was used to monitor a step-by-step gradual structure transformation from distinct mainly organic-inorganic hybrid materials into highly ordered CH3NH3PbI3 crystal during annealing...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28422368/safety-and-efficacy-of-pulmonary-vein-isolation-using-a-surround-flow-catheter-with-contact-force-measurement-capabilities-a-multicenter-registry
#2
Giuseppe Stabile, Paolo Di Donna, Vincenzo Schillaci, Antonio Di Monaco, Assunta Iuliano, Domenico Caponi, Francesco Urraro, Francesco Solimene, Massimo Grimaldi, Marco Scaglione
INTRODUCTION: Pulmonary vein (PV) isolation is the cornerstone of catheter ablation in patients with atrial fibrillation (AF). Surround flow and contact force (CF) measurement capabilities might enhance procedure efficacy and safety. We report on the safety and mid-term efficacy of a novel ablation catheter for PV isolation in patients with AF. METHODS AND RESULTS: Two hundred thirty-three consecutive patients (57±11 years, 76% males, 51% with structural heart disease) referred for paroxysmal (157) or persistent (76) AF, underwent PV isolation by a surround flow catheter with CF measurement capability in 4 centers...
April 19, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28421915/use-of-a-modified-classic-bt-shunt-in-a-patient-with-multiple-conduit-obstructions-with-positive-lupus-anticoagulant
#3
Pallav Bhattarai, Ayesha Zia, Joseph M Forbess, Kristine J Guleserian, Susan R Hupp, Timothy Pirolli
The use of a right ventricle-to-pulmonary artery conduit has re-emerged as a popular alternative to a systemic artery-to-pulmonary artery shunt in the Norwood procedure. Both proximal obstruction secondary to dynamic compression and distal obstruction at the anastomosis site with the pulmonary arteries are well described. In an effort to prevent complications, a technique where in the conduit is placed through the entire full thickness, or dunked, through the RV free wall has been described. We report a case of a patient with HLHS and positive lupus anticoagulant who developed recurrent conduit obstructions...
January 1, 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28416777/intervention-therapy-for-portal-vein-stenosis-occlusion-after-pediatric-liver-transplantation
#4
Haijun Gao, Hao Wang, Guang Chen, Zhengjia Yi
BACKGROUND The aim of this study was to investigate the outcomes and stent implantation timing of portal vein stenosis intervention after pediatric liver transplantation (pLT). MATERIAL AND METHODS The clinical data of 30 children with post-liver transplantation portal vein stenosis/occlusion (PVS/O) between Jan 2008 and Jun 2015 were retrospectively analyzed. The successfully re-opened cases used balloon angioplasty or stent implantation. SPSS13.0 software was used for statistical analysis and paired t test of the pressure gradient at both ends of the stenosis, diameter and flow rate within the stenosis, platelet count, and albumin in the PVS children before and after balloon angioplasty, with p<0...
April 18, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28415324/scale-dependence-of-multiplier-distributions-for-particle-concentration-enstrophy-and-dissipation-in-the-inertial-range-of-homogeneous-turbulence
#5
Thomas Hartlep, Jeffrey N Cuzzi, Brian Weston
Turbulent flows preferentially concentrate inertial particles depending on their stopping time or Stokes number, which can lead to significant spatial variations in the particle concentration. Cascade models are one way to describe this process in statistical terms. Here, we use a direct numerical simulation (DNS) dataset of homogeneous, isotropic turbulence to determine probability distribution functions (PDFs) for cascade multipliers, which determine the ratio by which a property is partitioned into subvolumes as an eddy is envisioned to decay into smaller eddies...
March 2017: Physical Review. E
https://www.readbyqxmd.com/read/28414799/comprehensive-evaluation-of-ten-deformable-image-registration-algorithms-for-contour-propagation-between-ct-and-cone-beam-ct-images-in-adaptive-head-neck-radiotherapy
#6
Xin Li, Yuyu Zhang, Yinghua Shi, Shuyu Wu, Yang Xiao, Xuejun Gu, Xin Zhen, Linghong Zhou
Deformable image registration (DIR) is a critical technic in adaptive radiotherapy (ART) for propagating contours between planning computerized tomography (CT) images and treatment CT/cone-beam CT (CBCT) images to account for organ deformation for treatment re-planning. To validate the ability and accuracy of DIR algorithms in organ at risk (OAR) contour mapping, ten intensity-based DIR strategies, which were classified into four categories-optical flow-based, demons-based, level-set-based and spline-based-were tested on planning CT and fractional CBCT images acquired from twenty-one head & neck (H&N) cancer patients who underwent 6~7-week intensity-modulated radiation therapy (IMRT)...
2017: PloS One
https://www.readbyqxmd.com/read/28414667/the-mysterious-case-of-dyspnea
#7
S Saad, N Turaga, J Grant, N Jain
INTRODUCTION: Dehiscence of a mitral valve annuloplasty ring is a rare occurrence that often manifests as mitral regurgitation and heart failure. We present a case of mitral ring dehiscence which was initially unrecognized by standard 2-dimensional transthoracic echocardiography (2D TTE); and 2-dimensional transesophageal echocardiography (2D TEE);. CASE: A 65-year-old woman was referred to Cardiology clinic for evaluation of dyspnea. Her history included tobacco abuse, atrial fibrillation status post pulmonary vein isolation, nonischemic cardiomyopathy, and prior mitral valve repair with annuloplasty ring for rheumatic valvular disease...
March 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28413903/digital-revascularization-and-replantation-using-the-wide-awake-hand-surgery-technique
#8
Jkf Wong, C H Lin, N J Chang, H C Chen, Y T Lin, C C Hsu
The use of local anaesthesia and adrenaline for hand surgery is gaining popularity; however, where vascularity is impaired, wide-awake surgery is considered a contraindication. We present our case series of five digital devascularizations and eight amputations that underwent surgery using the 'wide-awake' anaesthetic technique. A temporary digital tourniquet (< 20 min) was used in three cases to identify structures quickly. The anastomoses were performed under local anaesthesia without a tourniquet. All cases had successful re-establishment of blood flow with good perfusion to the digital tips; no cases were re-explored because of vascular crisis...
April 1, 2017: Journal of Hand Surgery, European Volume
https://www.readbyqxmd.com/read/28413846/a-carbon-balance-model-for-the-great-dismal-swamp-ecosystem
#9
Rachel Sleeter, Benjamin M Sleeter, Brianna Williams, Dianna Hogan, Todd Hawbaker, Zhiliang Zhu
BACKGROUND: Carbon storage potential has become an important consideration for land management and planning in the United States. The ability to assess ecosystem carbon balance can help land managers understand the benefits and tradeoffs between different management strategies. This paper demonstrates an application of the Land Use and Carbon Scenario Simulator (LUCAS) model developed for local-scale land management at the Great Dismal Swamp National Wildlife Refuge. We estimate the net ecosystem carbon balance by considering past ecosystem disturbances resulting from storm damage, fire, and land management actions including hydrologic inundation, vegetation clearing, and replanting...
December 2017: Carbon Balance and Management
https://www.readbyqxmd.com/read/28408434/renal-and-vascular-effects-of-uric-acid-lowering-in-normouricemic-patients-with-uncomplicated-type-1-diabetes
#10
Yuliya Lytvyn, Ronnie Har, Amy Locke, Vesta Lai, Derek Fong, Andrew Advani, Bruce A Perkins, David Z I Cherney
Higher plasma uric acid (PUA) levels are associated with lower GFR and higher blood pressure (BP) in patients with type 1 diabetes (T1D). Our aim was to determine the impact of PUA lowering on renal and vascular function in patients with uncomplicated T1D.T1D patients (n=49) were studied under eu- and hyperglycemic conditions at baseline and after PUA lowering with febuxostat (FBX) for 8 weeks. Healthy controls (HC) were studied under normoglycemic conditions (n=24). PUA, GFR (inulin), effective renal plasma flow (ERPF, paraaminohippurate), BP and hemodynamic responses to an infusion of angiotensin II (assessment of intrarenal RAAS) were measured pre- and post-FBX...
April 13, 2017: Diabetes
https://www.readbyqxmd.com/read/28407394/efficacy-and-safety-of-onabotulinumtoxina-injection-in-patients-with-refractory-overactive-bladder-first-multicentric-study-in-turkish-population
#11
Kadir Onem, Omer Bayrak, Abdullah Demirtas, Burhan Coskun, Murat Dincer, Izzet Kocak, Rahmi Onur
AIMS: To investigate the efficacy and safety of intradetrusor onabotulinumtoxinA (onaBoNT-A) injection in patients with overactive bladder (OAB) refractory to antimuscarinic treatment. METHODS: A total of 80 patients with OAB symptoms were enrolled in this prospective multicenter study and received 100 U intradetrusor onaBoNT-A injection.The changes from baseline in the frequency of voiding, urge urinary incontinence (UI) and urge episodes, mean and maximum bladder capacities, uroflowmetry, post-void residual urine volume (PVR), quality of life score, and treatment benefit scale score were assessed...
April 13, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28407232/observed-survival-benefit-of-therapeutic-hypothermia-re-analyzing-the-circ-trial
#12
Alexander Nürnberger, Harald Herkner, Fritz Sterz, Jan-Aage Olsen, Michael Lozano, Pierre M van Grunsven, Brooke E Lerner, David Persse, Reinhard Malzer, Marc A Brouwer, Mark Westfall, Chris M Souders, David T Travis, Ulrich R Herken, Lars Wik
BACKGROUND: Mild therapeutic hypothermia is argued being beneficial for outcome after cardiac arrest. MATERIALS AND METHODS: Retrospective analysis of Circulation Improving Resuscitation Care trial data to assess if therapeutic cooling to 33 ±1°C core temperature had an association with survival. Of 4,231 adult out-of-hospital cardiac arrests of presumed cardiac origin initially enrolled, eligibility criteria for therapeutic hypothermia were met by 1,812. Logistic regression was undertaken in a stepwise fashion to account for the impact on outcome of each significant difference and for the variable of interest between the groups...
April 13, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28405842/egfr-targeting-peptide-coupled-platinum-iv-complexes
#13
Josef Mayr, Sonja Hager, Bettina Koblmüller, Matthias H M Klose, Katharina Holste, Britta Fischer, Karla Pelivan, Walter Berger, Petra Heffeter, Christian R Kowol, Bernhard K Keppler
The high mortality rate of lung cancer patients and the frequent occurrence of side effects during cancer therapy demonstrate the need for more selective and targeted drugs. An important and well-established target for lung cancer treatment is the occasionally mutated epidermal growth factor receptor (EGFR). As platinum(II) drugs are still the most important therapeutics against lung cancer, we synthesized in this study the first platinum(IV) complexes coupled to the EGFR-targeting peptide LARLLT (and the shuffled RTALLL as reference)...
April 12, 2017: Journal of Biological Inorganic Chemistry: JBIC
https://www.readbyqxmd.com/read/28405763/five-year-outcomes-of-thulium-vapoenucleation-of-the-prostate-for-symptomatic-benign-prostatic-obstruction
#14
A J Gross, A K Orywal, B Becker, C Netsch
INTRODUCTION AND OBJECTIVES: To assess the 5-year outcomes of thulium vapoenucleation of the prostate (ThuVEP) in patients with benign prostatic obstruction (BPO) retrospectively. METHODS: Five-hundred patients were treated with ThuVEP between January 2007 and January 2010 at our institution. Patients were reassessed 1 and 5-years after ThuVEP with International Prostate Symptom Score (IPSS), Quality of Life (QoL), urinary peak flow (Qmax), postvoid residual volume (PVR), PSA and prostate volume...
April 12, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28403592/comparison-of-transurethral-incision-of-the-prostate-and-silodosin-in-patients-having-benign-prostatic-obstruction-in-terms-of-retrograde-ejaculation
#15
Basri Cakiroglu, Aydin Ismet Hazar, Orhun Sinanoglu, Ersan Arda, Sinan Ekici
BACKGROUND: To compare the functional outcomes and retrograde ejaculation (RE) after transurethral incision of the prostate (TUIP) or silodosin in bladder outlet obstruction (BOO) secondary to a small prostate. METHODS: Prospectively collected data from December 2011 through December 2014 of 192 LUTS patients having fertility concerns with prostate volume smaller than 40 ml receiving either TUIP or silodosin treatment were prospectively reviewed. The treatment outcomes were evaluated and compared...
March 31, 2017: Archivio Italiano di Urologia, Andrologia
https://www.readbyqxmd.com/read/28393124/a-leishmania-murine-model-to-evaluate-the-immunomodulatory-properties-of-pythium-insidiosum-proteins
#16
Tatiana Maria Inêz-Ferreira, Leonel Mendoza, Raquel Vilela, Hélida Monteiro de Andrade, João Paulo Haddad, Fernanda Freire Campos Nunes, Isabela Moreira Gondim, Tânia Mara Pinto Dabés Guimarães, Vicente de Paulo Coelho Peixoto de Toledo
Pythium insidiosum immunomodulatory vaccine (PiV) has been tested in clinical and experimental pythiosis. Previous data showed that P. insidiosum immunogens have the ability to switch the Th2 immune response, normally in place during pythiosis, to a curative Th1 response. Pythiosis cannot be reproduced in experimental rodents with the exception of rabbits, and thus thorough evaluation of PiV´s immunomodulatory properties has been limited by the lack of a compatible inbred mouse model. In this study, we took advantage of the murine BALB/c Leishmania infection model, where infected mice produce a Th2 response, to evaluate the PiV Th2 to Th1 immunomodulatory potential...
March 2017: Heliyon
https://www.readbyqxmd.com/read/28392691/ketoprofen-loaded-eudragit-electrospun-nanofibers-for-the-treatment-of-oral-mucositis
#17
Rana Ihab Reda, Ming Ming Wen, Amal Hassan El-Kamel
PURPOSE: The purpose of this study was to formulate ketoprofen (KET)-loaded Eudragit L and Eudragit S nanofibers (NFs) by the electrospinning technique for buccal administration to treat oral mucositis as a safe alternative to orally administered KET, which causes gastrointestinal tract (GIT) side effects. MATERIALS AND METHODS: NFs were prepared by electrospinning using Eudragit L and Eudragit S. Several variables were evaluated to optimize NF formulation, such as polymer types and concentrations, applied voltage, flow rate and drug concentrations...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28387689/multisensory-control-of-a-straight-locomotor-trajectory
#18
Maxim Hanna, Joyce Fung, Anouk Lamontagne
Locomotor steering is contingent upon orienting oneself spatially in the environment. When the head is turned while walking, the optic flow projected onto the retina is a complex pattern comprising of a translational and a rotational component. We have created a unique paradigm to simulate different optic flows in a virtual environment. We hypothesized that non-visual (vestibular and somatosensory) cues are required for proper control of a straight trajectory while walking. This research study included 9 healthy young subjects walking in a large physical space (40×25m2) while the virtual environment is viewed in a helmet-mounted display...
2017: Journal of Vestibular Research: Equilibrium & Orientation
https://www.readbyqxmd.com/read/28387623/flow-diverter-devices-in-ruptured-intracranial-aneurysms-a-single-center-experience
#19
Emilio Lozupone, Mariangela Piano, Luca Valvassori, Luca Quilici, Guglielmo Pero, Emiliano Visconti, Edoardo Boccardi
OBJECTIVE In this single-center series, the authors retrospectively evaluated the effectiveness, safety, and midterm follow-up results of ruptured aneurysms treated by implantation of a flow diverter device (FDD). METHODS The records of 17 patients (12 females, 5 males, average World Federation of Neurosurgical Societies score = 2.9) who presented with subarachnoid hemorrhage (SAH) due to the rupture of an intracranial aneurysm treated with an FDD were retrospectively reviewed. Of 17 ruptured aneurysms, 8 were blood blister-like aneurysms and the remaining 9 were dissecting aneurysms...
April 7, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28385297/renal-tubular-nhe3-is-required-in-the-maintenance-of-water-and-sodium-chloride-homeostasis
#20
Robert A Fenton, Søren B Poulsen, Samantha de la Mora Chavez, Manoocher Soleimani, Jessica A Dominguez Rieg, Timo Rieg
The sodium/proton exchanger isoform 3 (NHE3) is expressed in the intestine and the kidney, where it facilitates sodium (re)absorption and proton secretion. The importance of NHE3 in the kidney for sodium chloride homeostasis, relative to the intestine, is unknown. Constitutive tubule-specific NHE3 knockout mice (NHE3(loxloxCre)) did not show significant differences compared to control mice in body weight, blood pH or bicarbonate and plasma sodium, potassium, or aldosterone levels. Fluid intake, urinary flow rate, urinary sodium/creatinine, and pH were significantly elevated in NHE3(loxloxCre) mice, while urine osmolality and GFR were significantly lower...
April 3, 2017: Kidney International
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