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https://www.readbyqxmd.com/read/29888100/growing-skull-fracture-case-report-after-rottweiler-bite-and-review-of-the-literature
#1
Cletus Cheyuo, Rahul Singh, Brandon Lucke-Wold, Cesar Serrano
Growing skull fracture remains a rare but clinically significant complication of traumatic skull fractures in children less than 3 years of age. Dog attacks on children commonly cause head and neck injuries. We report the first case of growing skull fracture caused by a Rottweiler bite in a 21 days old neonate. Early diagnosis and surgical repair resulted in excellent outcome.
2018: Journal of Neurology & Neurophysiology
https://www.readbyqxmd.com/read/29876169/primary-repair-of-a-complex-panfacial-fracture-by-dog-bite
#2
Cláiton Heitz, Guilherme Pivatto Louzada, Ricardo Augusto Conci, Renato Luiz Rodrigues, Guilherme Genehr Fritscher
Facial fractures due to dog attacks have an unknown incidence rate. To date, only 41 cases of canine bite trauma in a pediatric patient, associated with facial fracture, have been reported in the literature. As major species of involving dogs are the American pitbull terrier and rottweiler. Due to the intense kinematics of this trauma, the treatment becomes complex. Thus, attention to the primary repair of such complex lesions ensures satisfactory results, which is the focus of this discussion. The purpose of this review was to analyze how different ways to approach this type of trauma in children for clarification or correct management...
April 2018: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/29761545/comparison-of-the-large-muscle-group-widths-of-the-pelvic-limb-in-seven-breeds-of-dogs
#3
Seyyid Said Sabanci, Mehmet Kamil Ocal
Orthopaedic diseases are common in the pelvic limbs of dogs, and reference values for large muscle groups of the pelvic limb may aid in diagnosis such diseases. As such, the objective of this study was to compare the large muscle groups of the pelvic limb in seven breeds of dogs. A total of 126 dogs from different breeds were included, and the widths of the quadriceps, hamstring and gastrocnemius muscles were measured from images of the lateral radiographies. The width of the quadriceps was not different between the breeds, but the widths of the hamstring and gastrocnemius muscles were significantly different between the breeds...
May 14, 2018: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/29724721/setd2-is-recurrently-mutated-in-whole-exome-sequenced-canine-osteosarcoma
#4
Sharadha Sakthikumar, Ingegerd Elvers, Jaegil Kim, Maja L Arendt, Rachael Thomas, Jason Turner-Maier, Ross Swofford, Jeremy Johnson, Steven E Schumacher, Jessica Alföldi, Erik Axelsson, Guillermo Couto, William Kisseberth, Mats E Pettersson, Gad Getz, Jennifer R S Meadows, Jaime F Modiano, Matthew Breen, Marcin Kierczak, Karin Forsberg-Nilsson, Voichita D Marinescu, Kerstin Lindblad-Toh
Osteosarcoma (OSA) is a debilitating bone cancer that affects humans, especially children and adolescents. A homologous form of OSA spontaneously occurs in dogs, and its differential incidence observed across breeds allows for the investigation of tumor mutations in the context of multiple genetic backgrounds. Using whole-exome sequencing and dogs from three susceptible breeds (22 golden retrievers, 21 Rottweilers, and 23 greyhounds), we found that OSA tumors show a high frequency of somatic copy number alterations (SCNA) affecting key oncogenes and tumor suppressor genes...
May 3, 2018: Cancer Research
https://www.readbyqxmd.com/read/29643404/canine-napepld-associated-models-of-human-myelin-disorders
#5
K M Minor, A Letko, D Becker, M Drögemüller, P J J Mandigers, S R Bellekom, P A J Leegwater, Q E M Stassen, K Putschbach, A Fischer, T Flegel, K Matiasek, K J Ekenstedt, E Furrow, E E Patterson, S R Platt, P A Kelly, J P Cassidy, G D Shelton, K Lucot, D L Bannasch, H Martineau, C F Muir, S L Priestnall, D Henke, A Oevermann, V Jagannathan, J R Mickelson, C Drögemüller
Canine leukoencephalomyelopathy (LEMP) is a juvenile-onset neurodegenerative disorder of the CNS white matter currently described in Rottweiler and Leonberger dogs. Genome-wide association study (GWAS) allowed us to map LEMP in a Leonberger cohort to dog chromosome 18. Subsequent whole genome re-sequencing of a Leonberger case enabled the identification of a single private homozygous non-synonymous missense variant located in the highly conserved metallo-beta-lactamase domain of the N-acyl phosphatidylethanolamine phospholipase D (NAPEPLD) gene, encoding an enzyme of the endocannabinoid system...
April 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29629647/immunohistochemical-detection-of-p53-pten-rb-and-p16-in-canine-osteosarcoma-using-tissue-microarray
#6
Duncan S Russell, Lauren Jaworski, William C Kisseberth
Although inactivating mutations of tumor suppressor genes are well described in cell lines of canine osteosarcoma (OS), expression of tumor suppressor proteins in spontaneous disease is poorly characterized. We determined the immunohistochemical expression of p53, PTEN, Rb, and p16 in a large cohort of dogs with OS. Formalin-fixed, paraffin-embedded samples of canine OS were analyzed retrospectively. Primary tumor samples from 145 dogs, collected between 2003 and 2008, were evaluated by tissue microarray. Streptavidin-biotin complex immunohistochemistry was performed using monoclonal antibodies for Rb and PTEN and polyclonal antibodies for p16 and p53...
April 1, 2018: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/29457536/heritabilities-and-genetic-trends-for-elbow-score-as-recorded-by-the-new-zealand-veterinary-association-elbow-dysplasia-scheme-1992-2013-in-four-breeds-of-dog
#7
M Soo, N Lopez-Villalobos, A J Worth
AIM: To estimate the heritability of the New Zealand Veterinary Association (NZVA) elbow phenotype, obtain estimated breeding values (EBV) for the worst-elbow score and estimate the genetic trends for this trait in four populous breeds of dogs, using the records from the NZVA Canine Elbow Dysplasia Scheme database (1992-2013). METHODS: Overall, 4,070 elbow records from a pedigree of 11,311 dogs were available for animals scored between 1992 and 2013. The worst elbow score between the left and right elbows was identified for each dog and used for EBV analysis...
May 2018: New Zealand Veterinary Journal
https://www.readbyqxmd.com/read/29386673/resolution-of-esophageal-dysmotility-following-treatment-of-nasal-disease-in-a-dog
#8
Laura Harjes, Helene Le Pommellet, Eric Hostnik, Adam Rudinsky
A 2-year-old Rottweiler dog was evaluated for cough, regurgitation, and nasal discharge, and was subsequently diagnosed with sinonasal aspergillosis and secondary esophageal disease. Following treatment of sinonasal aspergillosis, all clinical signs resolved. To the authors' knowledge, this is the first report of resolution of esophageal dysfunction following treatment of sinonasal aspergillosis.
February 2018: Canadian Veterinary Journal. la Revue Vétérinaire Canadienne
https://www.readbyqxmd.com/read/29351196/a-case-report-of-disseminated-canine-histiocytic-sarcoma-in-trinidad-and-tobago
#9
Stacy Rajh, Karelma Frontera Acevedo, Gillian Williams, Indira Pargass, Alissa Bally, Rod Suepaul
Ocular histiocytic sarcomas (as a presenting part of disseminated histiocytic sarcoma) are not commonly diagnosed. A 10-year-old female intact Rottweiler presented to the School of Veterinary Medicine, Trinidad with buphthalmia and pain in the left eye. The cornea of the left eye appeared diffusely opaque with a conjunctival mucopurulent ocular discharge. A thorough ophthalmic assessment identified an intraocular proliferative tumor to which a unilateral enucleation was performed, however the animal died soon after...
January 19, 2018: Veterinary Sciences
https://www.readbyqxmd.com/read/29346056/esophageal-leiomyoma-in-a-dog-causing-esophageal-distension-and-treated-by-transcardial-placement-of-a-self-expanding-covered-nitinol-esophageal-stent
#10
Elisabeth M Robin, Pascaline B Pey, Pauline de Fornel-Thibaud, Pierre H M Moissonnier, Valérie Freiche
CASE DESCRIPTION A 10-year-old spayed female Rottweiler was referred for evaluation because of a 2-month history of regurgitation and weight loss, despite no apparent change in appetite. The dog had received antiemetic and antacid treatment, without improvement. CLINICAL FINDINGS Physical examination revealed a low body condition score (2/5), but other findings were unremarkable. Diffuse, global esophageal dilatation was noted on plain thoracic radiographs, and normal motility was confirmed through videofluoroscopic evaluation of swallowing...
February 1, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29245098/pit-bull-attack-causing-limb-threatening-vascular-trauma-a-case-series
#11
Patrick Harnarayan, Shariful Islam, Christi Ramsingh, Vijay Naraynsingh
INTRODUCTION: Non-fatal human dog bites are commonplace amongst animal attacks on human beings and these present with mainly skin and soft tissue injuries. However, they can also present with life threatening head and neck injuries, massive soft tissue trauma, as well as combined orthopedic and vascular extremity injuries where a high possibility of limb loss exists. PRESENTATION OF CASES: We present two adult dog bite victims with multiple bites inflicted by large canines identified as Pit-Bull Terriers...
2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29227139/phenotypic-hip-and-elbow-dysplasia-trends-in-rottweilers-and-labrador-retrievers-in-south-africa-2007-2015-are-we-making-progress
#12
COMPARATIVE STUDY
Robert M Kirberger
Canine hip and elbow dysplasia are major orthopaedic problems prevalent the world over, and South Africa is no exception. Hip and elbow dysplasia phenotypic status is certified by a number of different radiographic schemes in the world. South Africa uses the Fédération Cynologique Internationale system to certify hips, and the International Elbow Working Group scheme to certify elbows. One way of reducing these often crippling conditions is by selective breeding using only dogs with no or marginal dysplastic joints...
November 22, 2017: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/29201384/rottweilers-under-primary-veterinary-care-in-the-uk-demography-mortality-and-disorders
#13
Dan G O'Neill, Wee Yin Seah, David B Church, Dave C Brodbelt
Background: Rottweilers are reportedly predisposed to many disorders but accurate prevalence information relating to the general population are lacking. This study aimed to describe demography, mortality and commonly recorded diseases in Rottweilers under UK veterinary care. Clinical health records within the VetCompass Programme were explored for disorders recorded during 2013. Results: Rottweilers comprised 5321 (1.17%) of 455,557 dogs attending 304 clinics. Annual proportional birth rates dropped from 1...
2017: Canine Genetics and Epidemiology
https://www.readbyqxmd.com/read/29187176/frequency-of-dea-1-antigen-in-1037-mongrel-and-purebreed-dogs-in-italy
#14
E Carli, A Carminato, S Ravagnan, K Capello, M T Antognoni, A Miglio, T Furlanello, D Proverbio, E Spada, A Stefani, F Mutinelli, M Vascellari
BACKGROUND: The prevalence of dog erythrocyte antigen (DEA 1) in canine population is approximately 40-60%. Often data are limited to a small number of breeds and/or dogs. The aims of this study were to evaluate frequency of DEA 1 in a large population of purebred and mongrel dogs including Italian native breeds and to recognize a possible association between DEA 1 and breed, sex, and genetic and phenotypical/functional classifications of breeds. Frequencies of DEA 1 blood group collected from screened/enrolled blood donors and from healthy and sick dogs were retrospectively evaluated...
November 29, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/29152773/categorization-of-the-pelvic-limb-standing-posture-in-nine-breeds-of-dogs
#15
S S Sabanci, M K Ocal
The objective of the study was to categorize objectively nine breeds of healthy dogs according to pelvic limb standing posture. A total of 135 dogs from different breeds were used and the standing angles of the hip, stifle, and tarsal joints, together with the percentages of the greater trochanter, patella and tuber calcanei heights, with respect to crista iliaca height, were used as discriminant variables for the categorization of pelvic limb posture. All included breeds were allocated to three groups of the standing pelvic limb posture...
February 2018: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/29147599/prevalence-of-dog-erythrocyte-antigen-1-in-7-414-dogs-in-italy
#16
Anyela Andrea Medina Valentin, Alessandra Gavazza, George Lubas
The study aim was to establish the prevalence of DEA 1, the most immunogenic and clinically important blood group in canine blood transfusion, in 7,414 dogs from Italy. The potential sensitization risk following a first transfusion and the acute reaction risk following a second transfusion given without a cross-matching and blood typing test were also calculated. Dogs tested were purebred (4,798) and mongrel (2,616); 38.8% were DEA 1 negative and 61.2% were DEA 1 positive. High prevalence for DEA 1 positive blood type was found in Ariegeois and English Setter, whereas German Shepherd and Boxer had higher DEA 1 negative blood type...
2017: Veterinary Medicine International
https://www.readbyqxmd.com/read/28933959/what-makes-a-dog-adoptable-an-eye-tracking-investigation
#17
Sara Isgate, Justin J Couchman
Humans readily attribute personality and behavioral traits to dogs, and these attributions influence decisions about adoption. This study focused on how these attributions could be influenced by breed and pose by using pictures of four breeds (Doberman Pinscher, Golden Retriever, pit bull, and Rottweiler) in 4 poses (dog sitting alone, sitting with a human, standing alone, and walking on a leash with a human). Participants rated each picture on friendliness, aggressiveness, and adoptability. Eye-tracking technology identified which specific features were represented in each picture to determine whether they had any effect on the judgments...
January 2018: Journal of Applied Animal Welfare Science: JAAWS
https://www.readbyqxmd.com/read/28865206/the-animal-dependent-risk-factors-in-canine-osteosarcomas
#18
R Sapierzyński, M Czopowicz
Canine osteosarcoma (OSA) is a malignant neoplastic tumor, which develops from the primitive mesenchymal stem cell, that has or can acquire the capacity to produce neoplastic osteoid with possible neoplastic bone formation. Predisposition of some dog breeds to OSA indicates genetic background of oncogenesis. The aim of the study was to characterize animal-dependent risk factors for canine osteosarcoma development in Poland. The study was conducted on canine patients diagnosed cytologically or histopathologically as having OSA, and data on age, breed, sex, as well as tumor location and character were recorded...
March 1, 2017: Polish Journal of Veterinary Sciences
https://www.readbyqxmd.com/read/28836371/prior-joint-disease-is-associated-with-increased-risk-of-periarticular-histiocytic-sarcoma-in-dogs
#19
E K Manor, L E Craig, X Sun, C M Cannon
Periarticular histiocytic sarcoma (PAHS) is the most common synovial tumour in dogs and is characterized by aggressive local disease with a high rate of distant metastasis. Previously, an association between PAHS and prior joint disease has been demonstrated in the Bernese Mountain Dog breed and suggested in the Rottweiler. We hypothesized that this association would be present in other breeds and investigated this via a retrospective, case-controlled analysis. Cases were dogs diagnosed with PAHS of the stifle or elbow...
March 2018: Veterinary and Comparative Oncology
https://www.readbyqxmd.com/read/28697872/life-course-analysis-of-the-impact-of-mammary-cancer-and-pyometra-on-age-anchored-life-expectancy-in-female-rottweilers-implications-for-envisioning-ovary-conservation-as-a-strategy-to-promote-healthy-longevity-in-pet-dogs
#20
D J Waters, S S Kengeri, A H Maras, C L Suckow, E C Chiang
Mammary cancer and pyometra are important health hazards associated with ovary conservation in pet dogs. Early ovariohysterectomy may reduce the incidence of these two diseases, but an estimate of the extent to which the development of mammary cancer or pyometra adversely influences overall longevity is missing. As a first step toward addressing this knowledge gap, the results of a historical cohort study of Rottweilers that lived in North America are reported. Questionnaires completed by owners and veterinarians were used to obtain lifetime health and medical information on 242 female Rottweilers, including years of lifetime ovary exposure, age at death, and cause of death...
June 2017: Veterinary Journal
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