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https://www.readbyqxmd.com/read/28546888/vapor-phase-synthesized-fluoroacrylate-polymer-thin-films-thermal-stability-and-structural-properties
#1
Paul Christian, Anna Maria Coclite
In this study, the thermal, chemical and structural stability of 1H,1H,2H,2H-perfluorodecyl acrylate polymers (p-PFDA) synthetized by initiated chemical vapor deposition (iCVD) were investigated. PFDA polymers are known for their interesting crystalline aggregation into a lamellar structure that induces super-hydrophobicity and oleophobicity. Nevertheless, when considering applications which involve chemical, mechanical and thermal stresses, it is important to know the limits under which the crystalline aggregation and the resulting polymer properties are stable...
2017: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/28545049/first-cloned-bactrian-camel-camelus-bactrianus-calf-produced-by-interspecies-somatic-cell-nuclear-transfer-a-step-towards-preserving-the-critically-endangered-wild-bactrian-camels
#2
Nisar Ahmad Wani, Binoy S Vettical, Seung B Hong
Studies were conducted to explore the possibility of employing dromedary camel (Camelus dromedarius) oocytes as recipient cytoplasts for the development of interspecies somatic cell nuclear transfer (iSCNT) embryos using skin fibroblast cells of an adult Bactrian camel (Camelus bactrianus) and Llama (Llama glama) as donor nuclei. Also, the embryos reconstructed with Bactrian cells were transferred into the uterus of synchronized dromedary camel recipients to explore the possibility of using them as surrogate mothers...
2017: PloS One
https://www.readbyqxmd.com/read/28534910/synergy-of-the-mechanical-antifouling-and-permeation-properties-of-a-carbon-nanotube-nanohybrid-membrane-for-efficient-oil-water-separation
#3
Yanan Liu, Yanlei Su, Jialin Cao, Jingyuan Guan, Linyan Xu, Rannan Zhang, Mingrui He, Qi Zhang, Lin Fan, Zhongyi Jiang
For water treatment applications, fabricating a high permeation flux membrane with super-strong mechanical strength and excellent long-term antifouling properties remains a great challenge. In this study, robust, antifouling carbon nanotube (CNT) nanohybrid membranes have been fabricated for oil/water separation. Polyethyleneimine (PEI) with abundant amino groups and a hyperbranched structure is utilized to construct a nanocoating on a CNT surface to enhance their hydrophilicity through multiple interactions between PEI and CNTs...
May 23, 2017: Nanoscale
https://www.readbyqxmd.com/read/28523132/uniportal-transcervical-video-assisted-thoracoscopic-surgery-vats-approach-for-pulmonary-lobectomy-combined-with-transcervical-extended-mediastinal-lymphadenectomy-temla
#4
Marcin Zieliński, Mariusz Rybak, Katarzyna Solarczyk-Bombik, Michal Wilkojc, Wojciech Czajkowski, Sylweriusz Kosinski, Edward Fryzlewicz, Tomasz Nabialek, Juliusz Pankowski
BACKGROUND: To present the technique of uniportal transcervical video-assisted thoracoscopic surgery (VATS) approach for pulmonary lobectomy combined with transcervical extended mediastinal lymphadenectomy (TEMLA). METHODS: Transcervical extended approach utilizes a typical a 5-8 centimeters collar incision in the neck. The critical technical point enabling a wide access to the chest is an elevation of the sternal manubrium with a special retractor (modified Rochard frame, Asculap-Chifa Company)...
April 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28508624/temperature-treatment-of-highly-porous-zirconium-containing-metal-organic-frameworks-extends-drug-delivery-release
#5
Michelle H Teplensky, Marcus Fantham, Peng Li, Timothy C Wang, Joshua P Mehta, Laurence J Young, Peyman Z Moghadam, Joseph T Hupp, Omar K Farha, Clemens F Kaminski, David Fairen-Jimenez
Utilizing metal-organic frameworks (MOFs) as a biological carrier can lower the amount of active pharmaceutical ingredient (API) required in cancer treatments to provide a more efficacious therapy. In this work, we have developed a temperature treatment process for delaying the release of a model drug compound from the pores of NU-1000 and NU-901, while taking care to utilize these MOFs' large pore volume and size to achieve exceptional model drug loading percentages over 35 wt.%. Video-rate super-resolution microscopy reveals movement of MOF particles when located outside of the cell boundary, and their subsequent immobilization when taken up by the cell...
May 16, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28507662/fabrication-and-nanostructure-control-of-super-hierarchical-carbon-materials-from-heterogeneous-bottlebrushes
#6
Yeru Liang, Luyi Chen, Dongyang Zhuang, Hao Liu, Ruowen Fu, Mingqiu Zhang, Dingcai Wu, Krzysztof Matyjaszewski
Advances in the performances of many modern materials fundamentally depend upon the exploitation of new micro/nanostructures. Therefore, ingenious design of hierarchical structures through the mimicking of natural systems is of increasing importance. Currently, there is an urgent need for creation of multidimensional carbonaceous structures by integrating a customized hierarchical pore architecture and hybrid carbon framework. Here we report the pioneering fabrication of novel super-hierarchical carbons with a unique carbonaceous hybrid nanotube-interconnected porous network structure by utilizing well-defined carbon nanotube@polystyrene bottlebrushes as building blocks...
March 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28499798/pilot-trial-on-separation-conditions-for-diaper-recycling
#7
Kyung-Shin Kim, Hee-Sun Cho
By utilizing laboratory-scale tests, the optimal separation conditions for diaper recycling were identified, and then, these conditions were validated by a pilot trial. In this research, we determined the mass balances derived during various processing steps and identified the most feasible procedures to use for separating each material in the output flow. The results showed that drum screening was not able to remove all the fiber and super absorbent particles (SAP) in the plastic-rich fraction and that cellulose enzyme treatment can be a good solution...
May 9, 2017: Waste Management
https://www.readbyqxmd.com/read/28485713/super-resolution-imaging-of-a-2-5-kb-non-repetitive-dna-in-situ-in-the-nuclear-genome-using-molecular-beacon-probes
#8
Yanxiang Ni, Bo Cao, Tszshan Ma, Gang Niu, Yingdong Huo, Jiandong Huang, Danni Chen, Yi Liu, Bin Yu, Michael Q Zhang, Hanben Niu
High-resolution visualization of short non-repetitive DNA in situ in the nuclear genome is essential for studying looping interactions and chromatin organization in single cells. Recent advances in fluorescence in situ hybridization (FISH) using Oligopaint probes have enabled super-resolution imaging of genomic domains with a resolution limit of 4.9 kb. To target shorter elements, we developed a simple FISH method that uses molecular beacon (MB) probes to facilitate the probe-target binding, while minimizing non-specific fluorescence...
May 9, 2017: ELife
https://www.readbyqxmd.com/read/28482247/a-possible-biomarker-for-methadone-related-deaths
#9
Antonina Argo, Gianfranco Francesco Spatola, Stefania Zerbo, Cettina Sortino, Antonietta Lanzarone, Maria Laura Uzzo, Alessandro Pitruzzella, Fiorenza Farè, Gabriella Roda, Veniero Gambaro, Paolo Procaccianti, Steven B Karch
Methadone (MTH) concentrations in those dying of MTH toxicity totally overlap concentrations where the presence of MTH is only an incidental finding, making it very difficult to make distinctions in actual cases. A biomarker, be it anatomical or biochemical for MTH toxicity is badly needed, particularly if that markers were known to disrupt effective ventilation. Because the brainstem houses the regulatory centers for cardiorespiratory-control enters, it would seem to be the most likely anatomical site to seek abnormalities in cardiorespiratory control...
May 3, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28468313/a-novel-certificateless-signature-scheme-for-smart-objects-in-the-internet-of-things
#10
Kuo-Hui Yeh, Chunhua Su, Kim-Kwang Raymond Choo, Wayne Chiu
Rapid advances in wireless communications and pervasive computing technologies have resulted in increasing interest and popularity of Internet-of-Things (IoT) architecture, ubiquitously providing intelligence and convenience to our daily life. In IoT-based network environments, smart objects are embedded everywhere as ubiquitous things connected in a pervasive manner. Ensuring security for interactions between these smart things is significantly more important, and a topic of ongoing interest. In this paper, we present a certificateless signature scheme for smart objects in IoT-based pervasive computing environments...
May 1, 2017: Sensors
https://www.readbyqxmd.com/read/28465580/controllable-design-of-super-oscillatory-lenses-with-multiple-sub-diffraction-limit-foci
#11
Muyuan Li, Wenli Li, Haoyong Li, Yechuan Zhu, Yiting Yu
The conventional multifocal optical elements cannot precisely control the focal number, spot size, as well as the energy distribution in between. Here, the binary amplitude-type super-oscillatory lens (SOL) is utilized, and a robust and universal optimization method based on the vectorial angular spectrum (VAS) theory and the genetic algorithm (GA) is proposed, aiming to achieve the required focusing performance with arbitrary number of foci in preset energy distribution. Several typical designs of multifocal SOLs are demonstrated...
May 2, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28461431/political-economies-and-environmental-futures-for-the-sharing-economy
#12
Koen Frenken
The sudden rise of the sharing economy has sparked an intense public debate about its definition, its effects and its future regulation. Here, I attempt to provide analytical guidance by defining the sharing economy as the practice that consumers grant each other temporary access to their under-utilized physical assets. Using this definition, the rise of the sharing economy can be understood as occurring at the intersection of three salient economic trends: peer-to-peer exchange, access over ownership and circular business models...
June 13, 2017: Philosophical Transactions. Series A, Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/28458289/application-of-natural-ingredients-to-preventive-medicine
#13
Junko Yokota
 The super-aging society in Japan is currently experiencing growing demand for treatments that improve health and longevity. To develop new high-functional foods and search for pharmaceutical candidates among foods and natural products, it is necessary to promote organic collaboration among researchers in pharmacy, medicine, nutrition, and other fields to encourage joint utilization of their technologies. Recently, attempts have been made to use numerous foods and natural products to prevent or treat diseases based on scientific evidence...
2017: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
https://www.readbyqxmd.com/read/28456206/benchmark-coupled-cluster-g-tensor-calculations-with-full-inclusion-of-the-two-particle-spin-orbit-contributions
#14
Ajith Perera, Jürgen Gauss, Prakash Verma, Jorge A Morales
We present a parallel implementation to compute electron spin resonance g-tensors at the coupled-cluster singles and doubles (CCSD) level which employs the ACES III domain-specific software tools for scalable parallel programming, i.e., the super instruction architecture language and processor (SIAL and SIP), respectively. A unique feature of the present implementation is the exact (not approximated) inclusion of the five one- and two-particle contributions to the g-tensor [i.e., the mass correction, one- and two-particle paramagnetic spin-orbit, and one- and two-particle diamagnetic spin-orbit terms]...
April 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28455356/the-coordinating-role-of-iqgap1-in-the-regulation-of-local-endosome-specific-actin-networks
#15
Edward B Samson, David S Tsao, Jan Zimak, R Tyler McLaughlin, Nicholaus J Trenton, Emily M Mace, Jordan S Orange, Volker Schweikhard, Michael R Diehl
IQGAP1 is a large, multi-domain scaffold that helps orchestrate cell signaling and cytoskeletal mechanics by controlling interactions among a spectrum of receptors, signaling intermediates, and cytoskeletal proteins. While this coordination is known to impact cell morphology, motility, cell adhesion, and vesicular traffic, among other functions, the spatiotemporal properties and regulatory mechanisms of IQGAP1 have not been fully resolved. Herein, we describe a series of super-resolution and live-cell imaging analyses that identified a role for IQGAP1 in the regulation of an actin cytoskeletal shell surrounding a novel membranous compartment that localizes selectively to the basal cortex of polarized epithelial cells (MCF-10A)...
April 28, 2017: Biology Open
https://www.readbyqxmd.com/read/28452155/silicon-substituted-xanthene-dyes-and-their-unique-photophysical-properties-for-fluorescent-probes
#16
Takayuki Ikeno, Tetsuo Nagano, Kenjiro Hanaoka
Fluorescence imaging is a powerful technique for visualizing temporal and spatial changes of biological events in living samples by utilizing fluorescent probes whose properties are altered upon interaction with the target biomolecule. In the past few years, many fluorescent probes have been developed based on xanthene dyes in which the O atom at the 10-position is replaced with a Si atom, such as 2,7-N,N,N',N'-tetramethyl-9-dimethyl-10-hydro-9-silaanthracene (TMDHS), Si-rhodamines and TokyoMagentas. Interestingly, these fluorophores not only retain the advantages of the typical xanthene dyes, but also have a number of unique properties, including far-red to near-infrared emission...
April 28, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28451345/protein-based-fluorescent-nanoparticles-for-super-resolution-sted-imaging-of-live-cells
#17
Li Shang, Peng Gao, Haixia Wang, Radian Popescu, Dagmar Gerthsen, Gerd Ulrich Nienhaus
Development of nanoparticles for super-resolution imaging (sriNPs) can greatly enrich the toolbox of robust optical probes for biological studies. Moreover, sriNPs enable us to monitor the behavior of engineered nanomaterials in complex biological environments with high spatial resolution, which is important for advancing our understanding of nano-bio interactions. Up to now, reports on sriNPs have been scarce. In this work, we report a facile strategy to prepare protein-based fluorescent NPs that can be utilized as probes in super-resolution microscopy...
March 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28451202/specific-protein-labeling-with-caged-fluorophores-for-dual-color-imaging-and-super-resolution-microscopy-in-living-cells
#18
Sebastian Hauke, Alexander von Appen, Tooba Quidwai, Jonas Ries, Richard Wombacher
We present new fluorophore-conjugates for dual-color photoactivation and super-resolution imaging inside live mammalian cells. These custom-designed, photo-caged Q-rhodamines and fluoresceins are cell-permeable, bright and localize specifically to intracellular targets. We utilized established orthogonal protein labeling strategies to precisely attach the photoactivatable fluorophores to proteins with subsequent activation of fluorescence by irradiation with UV light. That way, diffusive cytosolic proteins, histone proteins as well as filigree mitochondrial networks and focal adhesion proteins were visualized inside living cells...
January 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28445806/patient-engagement-at-the-margins-health-care-providers-assessments-of-engagement-and-the-structural-determinants-of-health-in-the-safety-net
#19
Mark D Fleming, Janet K Shim, Irene H Yen, Ariana Thompson-Lastad, Sara Rubin, Meredith Van Natta, Nancy J Burke
Increasing "patient engagement" has become a priority for health care organizations and policy-makers seeking to reduce cost and improve the quality of care. While concepts of patient engagement have proliferated rapidly across health care settings, little is known about how health care providers make use of these concepts in clinical practice. This paper uses 20 months of ethnographic and interview research carried out from 2015 to 2016 to explore how health care providers working at two public, urban, safety-net hospitals in the United States define, discuss, and assess patient engagement...
June 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28435481/a-patient-centered-emergency-department-management-strategy-for-sickle-cell-disease-super-utilizers
#20
Grant G Simpson, Hallie R Hahn, Alex A Powel, Robert R Leverence, Linda A Morris, Lara G Thompson, Marc S Zumberg, Deepa J Borde, Joseph A Tyndall, Jonathan J Shuster, Donald M Yealy, Brandon R Allen
INTRODUCTION: A subpopulation of sickle-cell disease patients, termed super-utilizers, presents frequently to emergency departments (EDs) for vaso-occlusive events and may consume disproportionate resources without broader health benefit. To address the healthcare needs of this vulnerable patient population, we piloted a multidisciplinary intervention seeking to create and use individualized patient care plans that alter utilization through coordinated care. Our goals were to assess feasibility primarily, and to assess resource use secondarily...
April 2017: Western Journal of Emergency Medicine
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