keyword
MENU ▼
Read by QxMD icon Read
search

Immune veterinary

keyword
https://www.readbyqxmd.com/read/29789506/design-and-efficacy-of-nanogels-formulations-for-intranasal-administration
#1
REVIEW
Blessing A Aderibigbe, Tobeka Naki
Nanogels are drug delivery systems that can bypass the blood-brain barrier and deliver drugs to the desired site when administered intranasally. They have been used as a drug delivery platform for the management of brain diseases such as Alzheimer disease, migraine, schizophrenia and depression. nanogels have also been developed as vaccine carriers for the protection of bacterial infections such as influenza, meningitis, pneumonia and as veterinary vaccine carriers for the protection of animals from encephalomyelitis and mouth to foot disease...
May 23, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29771638/the-first-report-evaluating-the-post-exposure-rabies-prophylaxis-in-children-exposed-to-animals-in-the-lublin-province-eastern-poland-in-2010-2016-a-retrospective-study
#2
Joanna Krzowska-Firych, Ewelina Mazurek, Barbara Hasiec, Krzysztof Tomasiewicz
INTRODUCTION: Rabies continues to be one of the most important viral diseases and remains a significant threat to public health across the globe. The World Health Organization (WHO) has determined that most rabies cases occur in children. Dog bites on humans are a major public-health problem. Poland has not achieved rabies free status yet. Post-exposure prophylaxis (PEP) in humans can effectively prevent death after exposure to a potentially infected animal. THE AIM: The main objective of this study was to estimate the frequency of PEP among children exposed to animals, who had attended consultations at the Department of Infectious Diseases for Children in the Jan Boży Hospital in Lublin...
May 17, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29769086/inflammatory-pattern-of-the-infrapatellar-fat-pad-in-dogs-with-canine-cruciate-ligament-disease
#3
Manuel R Schmidli, Bettina Fuhrer, Nadine Kurt, David Senn, Michaela Drögemüller, Ulrich Rytz, David E Spreng, Simone Forterre
BACKGROUND: Despite the importance of inflammation during the pathogenesis of cranial cruciate ligament disease (CCLD) in dogs and despite the latest knowledge suggesting a significant role of adipose tissue in osteoarthritis, the infrapatellar fat pad (IFP) was up to now mostly disregarded in veterinary investigations. In the present study, the inflammatory activity of the IFP, the main adipose structure within the stifle joint, was thoroughly investigated to evaluate its potential impact in the pathogenesis of this common disease of our canine companions...
May 16, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29765971/alopecia-areata-in-a-dog-clinical-dermoscopic-and-histological-features
#4
Fabia Scarampella, Paola Roccabianca
Alopecia areata (AA)-like disease is characterized by multifocal patchy hair loss in humans, rodents, dogs, and horses. Remarkable similarities between human and nonhuman AA cases have been reported in terms of clinical presentation, histology, and immune mechanisms of the disease. Canine AA-like lesions most often consist of well-demarcated alopecic patches, frequently but not only involving the face and the head, which extend to the ear pinnae and legs. In some cases, hair loss can have a more generalized distribution...
April 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29751810/auto-immune-skin-diseases-in-animals-time-to-reclassify-and-review-after-40-years
#5
EDITORIAL
Thierry Olivry
It has been more than 40 years since the dual descriptions of canine pemphigus vulgaris. Over the ensuing four decades, the reports of-mostly canine-novel autoimmune skin diseases (AISDs) have progressed in successive waves separated by long periods of quiescence. This Editorial introduces a series of comprehensive review papers on the various canine and feline AISDs. This collection of articles aims at remediating the current veterinary literature deficiency on this topic by summarizing the key historical, clinical, histological, immunological and treatment characteristics of animal AISDs...
May 11, 2018: BMC Veterinary Research
https://www.readbyqxmd.com/read/29747390/functional-aspects-of-fish-mucosal-lectins-interaction-with-non-self
#6
REVIEW
Monica Fengsrud Brinchmann, Deepti Manjari Patel, Nevil Pinto, Martin Haugmo Iversen
Mucosal surfaces are of key importance in protecting animals against external threats including pathogens. In the mucosal surfaces, host molecules interact with non-self to prevent infection and disease. Interestingly, both inhibition and stimulation of uptake hinder infection. In this review, the current knowledgebase on teleost mucosal lectins’ ability to interact with non-self is summarised with a focus on agglutination, growth inhibition, opsonisation, cell adhesion, and direct killing activities...
May 9, 2018: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29746004/extracellular-vesicles-induce-protective-immunity-against-trichuris-muris
#7
R K Shears, A J Bancroft, G W Hughes, R K Grencis, D J Thornton
Gastrointestinal nematodes, such as Trichuris trichiura (human whipworm), are a major source of morbidity in humans and their livestock. There is a paucity of commercially available vaccines against these parasites, and vaccine development for T. trichiura has been impeded by a lack of known host protective antigens. Experimental vaccinations with T. muris (murine whipworm) soluble Excretory/Secretory (ES) material have demonstrated that it is possible to induce protective immunity in mice, however the potential for extracellular vesicles (EVs) as a source of antigenic material has remained relatively unexplored...
May 10, 2018: Parasite Immunology
https://www.readbyqxmd.com/read/29739469/biomarkers-for-monitoring-intestinal-health-in-poultry-present-status-and-future-perspectives
#8
REVIEW
Richard Ducatelle, Evy Goossens, Fien De Meyer, Venessa Eeckhaut, Gunther Antonissen, Freddy Haesebrouck, Filip Van Immerseel
Intestinal health is determined by host (immunity, mucosal barrier), nutritional, microbial and environmental factors. Deficiencies in intestinal health are associated with shifts in the composition of the intestinal microbiome (dysbiosis), leakage of the mucosal barrier and/or inflammation. Since the ban on growth promoting antimicrobials in animal feed, these dysbiosis-related problems have become a major issue, especially in intensive animal farming. The economical and animal welfare consequences are considerable...
May 8, 2018: Veterinary Research
https://www.readbyqxmd.com/read/29738815/the-conventional-pathogenic-flora-compositions-an-overview-of-the-trends-used-for-bacterial-pathogenicity-identifications
#9
REVIEW
Frank Anayo Orji, Ositadinma Chinyere Ugbogu, Eziuche Amadike Ugbogu, Alberto Barbabosa-Pliego, Jose Cedillo Monroy, Abdelfattah Z M Salem
Over 250 species of resident flora in the class of bacteria are known to be associated with humans. These conventional flora compositions is often determined by factors which may not be limited to stress, nutrition, genetics, and age, sex, stress, nutrition of humans. Man is constantly in contact with bacteria through media such as air, water, soil and food. This paper reviews the concept of bacterial pathogenesis from the sequential point of colonization to tissue injury. The paper in addition to examination of the factors which enhances virulence in bacterial pathogens also x-rayed the concept of pathogenicity islands and the next generation approaches or rather current trends/methods used in the bacterial pathogenicity investigations...
May 5, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29729717/immunohistochemical-characterization-of-immune-cell-infiltration-in-feline-glioma
#10
D R Rissi, B F Porter, C E Boudreau, P M Krimer, A D Miller
The relationship between inflammatory cells and tumour biology has been defined in many human intracranial neoplasms, but it is relatively poorly characterized in veterinary medicine. The aim of this study was to define the immune cell infiltration in cases of feline glioma and its possible association with tumour morphology and type. A retrospective search identified 18 gliomas that met inclusion criteria. Tumours were subjected to immunohistochemistry (IHC) for CD3, CD20, Iba1, MAC387 and factor VIII-related antigen...
April 2018: Journal of Comparative Pathology
https://www.readbyqxmd.com/read/29727898/-immunosuppressive-therapy-in-dogs-and-cats-properties-of-drugs-and-their-use-in-various-immune-mediated-diseases
#11
Johanna Rieder, Reinhard Mischke
Veterinarians are regularly faced with the diagnosis and therapy of immune-mediated diseases. More frequently occurring immune-mediated diseases are immune-mediated hemolytic anemia, immunemediated thrombocytopenia and polyarthritis. Glucocorticoids are commonly used as first-line treatment because of their availability, efficacy and rapid action. Nevertheless, some patients do not respond to glucocorticoid therapy alone. Others require a rapid dose reduction because of severe side effects from glucocorticoid treatment...
April 2018: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/29695422/isg-expression-screening-reveals-the-specific-antibunyaviral-activity-of-isg20
#12
Junjie Feng, Arthur Wickenhagen, Matthew L Turnbull, Veronica V Rezelj, Felix Kreher, Natasha L Tilston-Lunel, Gillian S Slack, Benjamin Brennan, Elina Koudriakova, Andrew E Shaw, Suzannah J Rihn, Charles M Rice, Paul D Bieniasz, Richard M Elliott, Xiaohong Shi, Sam J Wilson
Bunyaviruses pose a significant threat to human health, prosperity and food security. In response to viral infections, interferons (IFNs) upregulate the expression of hundreds of interferon stimulated genes (ISGs) whose cumulative action can potently inhibit the replication of bunyaviruses. We used a flow cytometry-based method to screen the ability of ∼500 unique ISGs from humans and rhesus macaques to inhibit the replication of Bunyamwera orthobunyavirus (BUNV), the prototype of both the Peribunyaviridae family and Bunyavirales order...
April 25, 2018: Journal of Virology
https://www.readbyqxmd.com/read/29688778/influence-of-immune-mediated-hemolytic-anemia-on-flow-velocities-in-the-portal-vein-and-caudal-vena-cava-measured-by-use-of-pulsed-wave-doppler-ultrasonography-in-dogs
#13
Rachel Policelli Smith, Amy M Koenigshof, Daniel J Smith, Phillip R Strom, Nathan C Nelson
OBJECTIVE To compare blood flow velocities of the portal vein (PV) and caudal vena cava (CVC) measured by use of pulsed-wave Doppler ultrasonography in clinically normal dogs and dogs with primary immune-mediated hemolytic anemia (IMHA). ANIMALS 11 client-owned dogs admitted to a veterinary teaching hospital for management of primary IMHA and 21 staff- or student-owned clinically normal dogs. PROCEDURES Flow velocities in the PV and CVC at the porta hepatis were evaluated in conscious unsedated dogs with concurrent ECG monitoring; evaluations were performed before dogs with IMHA received heparin or blood transfusions...
May 2018: American Journal of Veterinary Research
https://www.readbyqxmd.com/read/29666821/probiotics-for-the-control-of-helminth-zoonosis
#14
REVIEW
Abadi Amare Reda
This paper is a comprehensive, concise, and an up to date review about probiotics effect and mechanisms against helminth infections of zoonotic importance. Zoonoses are diseases that can be transmitted from animals to humans in a reversible way. Despite zoonotic helminth diseases being still a challenge to the public health and the agriculture industries globally, they were still neglected in both human and veterinary medicine. Moreover, the increasing emergence of anthelmintic drug resistance constitutes failures of most disease control strategies, alarming for a quest to new alternative control approaches...
2018: Journal of Veterinary Medicine
https://www.readbyqxmd.com/read/29580554/paramunity-inducing-factors-pinds-in-dendritic-cell-dc-cultures-lead-to-impaired-antileukemic-functionality-of-dc-stimulated-t-cells
#15
Christian Ansprenger, Valentin Vogt, Julia Schick, Annika Hirn-Lopez, Yvonne Vokac, Ihor Harabacz, Marion Braeu, Tanja Kroell, Axel Karenberg, Hans-Jochem Kolb, Helga Schmetzer
INTRODUCTION: Paramunity-inducing-Factors (PINDs) consist of attenuated/inactivated viruses of various poxvirus-genera, used in veterinary medicine as non-antigen-specific, non-immunising stimulators of the innate immune system against infectious and malignant diseases. Their danger-signaling-interactions were tested for their capacity to improve leukemic antigen-presentation on DC generated from AML-patients' blasts ('DCleu ') and DC-stimulation/activation of antileukemic T-cells. METHODS: We analyzed, whether the addition of PINDs during DC cultures (15 healthy, 22 leukemic donors) and mixed lymphocyte culture (MLC, n = 15) with autologous (n = 6), allogeneic (n = 2) or T-cells after stem cell transplantation (SCT; n = 7) would alter the quality and quantity of DC, the composition of T-cell-subsets, and/or their antileukemic functionality (AF) as studied by FACS and functional Fluorolysis-cytotoxicity-assays...
March 16, 2018: Cellular Immunology
https://www.readbyqxmd.com/read/29573261/development-of-novel-monoclonal-antibodies-to-dog-leukocyte-antigen-dr-displaying-direct-and-immune-mediated-cytotoxicity-toward-canine-lymphoma-cell-lines
#16
Marta Lisowska, Aleksandra Pawlak, Justyna Kutkowska, Wojciech Hildebrand, Maciej Ugorski, Andrzej Rapak, Arkadiusz Miazek
Spontaneous canine lymphoma (CL) has become a promising, nonrodent model for advancing the therapeutic strategies of human hematological malignancies. As new resources for veterinary and comparative studies on CL-associated antigens, we developed 2 novel mouse monoclonal antibodies, denoted B5 and E11, that recognized the canine major histocompatibility Class II DR antigens (dog leukocyte antigen DR). Using flow cytometry and solid phase immunoenzymatic assays, we showed that the antigens recognized by B5 and E11 were strongly expressed in several CL cell lines and the ex vivo canine neoplastic cells of B and mixed B/T immunophenotypes...
March 24, 2018: Hematological Oncology
https://www.readbyqxmd.com/read/29571514/development-and-characterization-of-monoclonal-antibodies-against-canine-pd-1-and-pd-l1
#17
Yuki Nemoto, Kazuha Shosu, Masaru Okuda, Shunsuke Noguchi, Takuya Mizuno
Recent research has focused on immunotherapy, particularly with regard to cancer treatment. Programmed death-1 and programmed death ligand 1 (PD-1/PD-L1) pathway blockade is a central topic of the promising immunotherapy field. In veterinary medicine, observations of the PD-1/PD-L1 pathway, including the relationship between immune cells and diseases, have increased. In this study, monoclonal antibodies specific to canine PD-1 and PD-L1 were developed, and the antibodies against PD-1 and PD-L1 bind to PD-1 and PD-L1 overexpressing cells, respectively...
April 2018: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/29559144/endocrine-immune-interactions-during-chronic-toxocariasis-caused-by-toxocara-canis-in-a-murine-model-new-insights-into-the-pathophysiology-of-an-old-infection
#18
Víctor Hugo Del Río-Araiza, Karen Elizabeth Nava-Castro, Fernando Alba-Hurtado, Andrés Quintanar-Stephano, Marco Antonio Muñoz-Guzmán, Olga CUenca-Micò, Jorge Morales-Montor
Toxocara canis is the helminth causing Toxocariasis, a parasitic disease with medical and veterinary implications. Their final host are members of the family Canidae and as paratenic hosts, most of the mammals are sensitive (man, rat, mouse, among others). It has been reported that a pituitary hormone, prolactin, it is responsible for reactivation and migration of larvae to the uterus and mammary gland during the last third of gestation in bitches. In addition, this hormone has been shown to play an important role in the regulation of the immune response...
March 15, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29554974/renal-dialysis-and-long-term-treatment-of-a-dog-with-kidney-disease-associated-with-canine-leishmaniosis
#19
Gad Baneth, Gilad Segev, Michal Mazaki-Tovi, Hila Chen, Sharon Kuzi
BACKGROUND: Renal disease is considered the main cause of natural mortality in dogs with canine leishmaniosis. The pathological mechanisms associated with kidney injury in canine leishmaniosis include immune complex glomerulonephritis, tubulointerstitial nephritis and occasionally renal amyloidosis. Proteinuria is a frequent finding in canine leishmaniosis and its quantification by the urine protein-creatinine ratio (UPC) is an important parameter in the staging of canine lesihmaniosis as presented by the LeishVet group...
March 20, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29549327/a-proteomic-insight-into-vitellogenesis-during-tick-ovary-maturation
#20
Marina Amaral Xavier, Lucas Tirloni, Antônio F M Pinto, Jolene K Diedrich, John R Yates, Albert Mulenga, Carlos Logullo, Itabajara da Silva Vaz, Adriana Seixas, Carlos Termignoni
Ticks are arthropod ectoparasites of importance for public and veterinary health. The understanding of tick oogenesis and embryogenesis could contribute to the development of novel control methods. However, to date, studies on the temporal dynamics of proteins during ovary development were not reported. In the present study we followed protein profile during ovary maturation. Proteomic analysis of ovary extracts was performed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) using shotgun strategy, in addition to dimethyl labelling-based protein quantification...
March 16, 2018: Scientific Reports
keyword
keyword
27281
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"