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https://www.readbyqxmd.com/read/28732085/point-of-care-screening-for-hepatitis-b-virus-infection-in-pregnant-women-at-an-antenatal-clinic-a-south-african-experience
#1
Nafiisah Chotun, Wolfgang Preiser, Christoffel Johannes van Rensburg, Pedro Fernandez, Gerhard Barnard Theron, Dieter Glebe, Monique Ingrid Andersson
BACKGROUND & AIMS: Elimination of HIV and syphilis mother-to-child transmission (MTCT) has received much attention but little consideration has been given to the possibility of elimination of HBV MTCT. In sub-Saharan Africa, HBV vertical transmission continues to be reported and it remains an important public health problem. This study aimed to assess the feasibility of screening pregnant women for HBV using a point-of-care (POC) test and implementing interventions to prevent HBV MTCT...
2017: PloS One
https://www.readbyqxmd.com/read/28732006/drivers-for-rift-valley-fever-emergence-in-mayotte-a-bayesian-modelling-approach
#2
Raphaëlle Métras, Guillaume Fournié, Laure Dommergues, Anton Camacho, Lisa Cavalerie, Philippe Mérot, Matt J Keeling, Catherine Cêtre-Sossah, Eric Cardinale, W John Edmunds
Rift Valley fever (RVF) is a major zoonotic and arboviral hemorrhagic fever. The conditions leading to RVF epidemics are still unclear, and the relative role of climatic and anthropogenic factors may vary between ecosystems. Here, we estimate the most likely scenario that led to RVF emergence on the island of Mayotte, following the 2006-2007 African epidemic. We developed the first mathematical model for RVF that accounts for climate, animal imports and livestock susceptibility, which is fitted to a 12-years dataset...
July 21, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28731980/running-performance-nationality-sex-and-age-in-the-10-km-half-marathon-marathon-and-the-100-km-ultramarathon-iaaf-1999-2015
#3
Pantelis T Nikolaidis, Vincent O Onywera, Beat Knechtle
Nikolaidis PT, Onywera VO, and Knechtle B. Running performance, nationality, sex, and age in the 10-km, half-marathon, marathon, and the 100-km ultramarathon IAAF 1999-2015. J Strength Cond Res 31(8): 2189-2207, 2017-The aim of this study was to examine the performance of the world's best runners in the 10-km, half-marathon, marathon, and 100-km races by age, sex, and nationality during 1999-2015, using data from the International Association of Athletics Federations (IAAF). A total of 38,895 runners (17,136 women and 21,759 men) were evaluated, with 2,594 (1,360 women and 1,234 men) in the 10-km; 11,595 (5,225 women and 6,370 men) in the half-marathon; 23,973 (10,208 women and 13,765 men) in the marathon; and 733 (343 women and 390 men) in 100-km events...
August 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28731899/current-perspectives-on-invasive-nontyphoidal-salmonella-disease
#4
Andrea H Haselbeck, Ursula Panzner, Justin Im, Stephen Baker, Christian G Meyer, Florian Marks
PURPOSE OF REVIEW: We searched PubMed for scientific literature published in the past 2 years for relevant information regarding the burden of invasive nontyphoidal Salmonella disease and host factors associated with nontyphoidal Salmonella infection and discuss current knowledge on vaccine development. The following search terms were used: Salmonella, non typhoidal/nontyphoidal, NTS, disease, bloodstream infection, invasive, sepsis/septicaemia/septicemia, bacteraemia/bacteremia, gastroenteritis, incidence, prevalence, morbidity, mortality, case fatality, host/risk factor, vaccination, and prevention/control...
July 20, 2017: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/28731588/human-leukocyte-antigen-distribution-and-genomic-ancestry-in-brazilian-patients-with-sickle-cell-disease
#5
M C F da Silva-Malta, P S Rodrigues, L W Zuccherato, F C B de Souza, E M F L Domingues, V R Souza, E Tarazona-Santos, M L Martins
Hematopoietic stem-cell transplantation (HSCT) is currently the only established curative treatment for sickle cell disease (SCD), but is limited by donor availability. Ethnicity is thought to have an impact on the complications experienced by patients that undergo HSCT and on the likelihood of identifying an HLA matched donor. In the present study, we investigated the genomic ancestry and the distribution of HLA allele groups in Brazilian patients with SCD, compared these HLA profiles to worldwide populations and evaluate the availability of HLA-matched donors...
July 21, 2017: HLA
https://www.readbyqxmd.com/read/28731541/demography-and-genome-divergence-of-lake-and-stream-populations-of-an-east-african-cichlid-fish
#6
Bernd Egger, Marius Rösti, Astrid Böhne, Olivia Roth, Walter Salzburger
Disentangling the processes and mechanisms underlying divergent selection in diversification is facilitated by the comparative study of replicate population pairs that have diverged along a similar environmental gradient. Such a setting is realized in a cichlid fish from southern Lake Tanganyika, Astatotilapia burtoni, which occurs both within the lake proper as well as in various affluent rivers. Previous studies demonstrated that independent lake and stream populations show respectively similar adaptations to the two habitat regimes...
July 21, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28731440/challenges-and-considerations-related-to-studying-dementia-in-african-americans
#7
Eseosa T Ighodaro, Peter T Nelson, Walter A Kukull, Frederick A Schmitt, Erin L Abner, Allison Caban-Holt, Shoshana H Bardach, Derrick C Hord, Crystal M Glover, Gregory A Jicha, Linda J Van Eldik, Alexander X Byrd, Anita Fernander
Blacks/African Americans have been reported to be ∼2-4 times more likely to develop clinical Alzheimer's disease (AD) compared to Whites. Unfortunately, study design challenges (e.g., recruitment bias), racism, mistrust of healthcare providers and biomedical researchers, confounders related to socioeconomic status, and other sources of bias are often ignored when interpreting differences in human subjects categorized by race. Failure to account for these factors can lead to misinterpretation of results, reification of race as biology, discrimination, and missed or delayed diagnoses...
July 19, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28731216/indigenous-food-ingredients-for-complementary-food-formulations-to-combat-infant-malnutrition-in-benin-a-review
#8
REVIEW
Flora J Chadare, Yann E Madode, Nadia Fanou-Fogny, Janvier M Kindossi, Juvencio O Ayosso, Hermann S Honfo, Polycarpe Kayode, Anita R Linnemann, Joseph D Hounhouigan
This paper reviews indigenous Beninese food resources as potential ingredients for complementary infant foods with the aim to develop affordable formulations for low-income households in each agro-ecological zone of the country. Potential ingredients were selected on their documented nutritional value. The selected foods encompass 347 food resources, namely 297 plant products from home gardens or collected from natural vegetation and 50 animals, either domesticated or from the wild. The compiled data reveal that the distribution of the available food resources was unbalanced between agro-ecological zones...
July 21, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28730704/the-athena-hpv-study-underrepresents-other-high-risk-hpv-genotypes-when-compared-with-a-diverse-new-york-city-population
#9
G Ramos Rivera, S N Khader, S Lajara, K Schlesinger, D Y Goldstein, R C Naeem, M J Suhrland, A S Fox
OBJECTIVE: Persistent infection with oncogenic high risk HPV (hrHPV) types causes virtually all cases of cervical cancer. HPV 16 and 18 have been targeted for individual genotyping and vaccination because of their presence in 71% of invasive cervical cancers worldwide. Montefiore Medical Center, Bronx, New York serves a population known for ethnic and racial diversity. Given this diversity it is possible that HPV genotypes not individually detected by current testing are causing significant disease...
July 21, 2017: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/28730576/effects-of-boron-supplementation-on-expression-of-hsp70-in-the-spleen-of-african-ostrich
#10
Khaliq Haseeb, Jing Wang, Ke Xiao, Ke-Li Yang, Peng-Peng Sun, Xing-Tong Wu, You Luo, Hui Song, Hua-Zhen Liu, Ju-Ming Zhong, Ke-Mei Peng
Increased synthesis of heat shock protein 70 (Hsp70) occurs in prokaryotes and eukaryotes in response to physiological, environmental, and chemical exposures, thus allowing the cell survival from fatal conditions. Hsp70 cytoprotective properties may be clarified by its anti-apoptotic function. Boron has been reported to play an essential role in various organ developments and metabolisms. However, it is not known if boron is also able to modulate the Hsp70. In the present study, the actions of boron on ostrich spleen and expression level of Hsp70 were investigated...
July 20, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28730559/fathers-know-best-inner-city-african-american-fathers-perceptions-regarding-their-involvement-in-the-pediatric-medical-home
#11
Orville Newton-Ray Bignall, Whitney J Raglin Bignall, Lisa M Vaughn, Ndidi I Unaka
OBJECTIVE: Despite nearly three in four African American (AA) children being born to unwed mothers, AA fathers maintain relatively high levels of parenting engagement, whether or not they live with their children. While father involvement correlates with decreased adverse child health outcomes, the nature of AA father involvement in child health-including engagement in the pediatric medical home-remains largely unexplored. Our study aimed to assess perceptions of pediatric medical home participation among a cohort of urban, AA fathers...
July 20, 2017: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/28730185/social-networks-as-predictors-of-colorectal-cancer-screening-in-african-americans
#12
Ernest Alema-Mensah, Selina A Smith, Mechelle Claridy, Victor Ede, Benjamin Ansa, Daniel S Blumenthal
BACKGROUND: Early detection can reduce colorectal cancer (CRC) mortality by 15%-33%, and screening is widely recommended for average-risk adults beginning at age 50 years. Colorectal cancer mortality rates are higher in African Americans than in whites, while screening rates are somewhat lower. Individual social networks can reduce emotional and/or logistical barriers to health-promoting but distasteful procedures such as CRC screening. The aim of this study was to examine social network interactions, and their impact on CRC screening among African Americans...
2017: Journal of the Georgia Public Health Association
https://www.readbyqxmd.com/read/28730069/exploration-of-the-academic-lives-of-students-with-disabilities-at-south-african-universities-lecturers-perspectives
#13
Oliver Mutanga, Melanie Walker
BACKGROUND: A decade has passed since South Africa signed and ratified the Convention on the Rights of Persons with Disabilities, a human rights treaty that protects the rights and dignity of people with disabilities. However, not much have changed for students with disabilities. OBJECTIVES: The aim of this study was to explore lecturers' experiences with, and perspectives on, disability as well as with students with disabilities. It was hoped that this would contribute to the ongoing policy debates about diversity, inclusion and support for students with disabilities at universities...
2017: Afr J Disabil
https://www.readbyqxmd.com/read/28730067/practices-and-discourses-of-ubuntu-implications-for-an-african-model-of-disability
#14
Maria Berghs
BACKGROUND: Southern African scholars and activists working in disability studies have argued that ubuntu or unhu is a part of their world view. OBJECTIVES: Thinking seriously about ubuntu, as a shared collective humanness or social ethics, means to examine how Africans have framed a struggle for this shared humanity in terms of decolonisation and activism. METHOD: Three examples of applications of ubuntu are given, with two mainly linked to making explicit umaka...
2017: Afr J Disabil
https://www.readbyqxmd.com/read/28730063/community-stakeholders-perspectives-on-the-role-of-occupational-therapy-in-primary-healthcare-implications-for-practice
#15
Deshini Naidoo, Jacqueline Van Wyk, Robin Joubert
BACKGROUND: Primary healthcare (PHC) is central to increased access and transformation in South African healthcare. There is limited literature about services required by occupational therapists in PHC. Despite policy being in place, the implementation of services at grassroots level does not always occur adequately. OBJECTIVES: This study aimed at gaining an understanding of the challenges of being disabled and the services required by occupational therapists (OTs) in rural communities in order to better inform the occupational therapy (OT) training curriculum...
2017: Afr J Disabil
https://www.readbyqxmd.com/read/28729732/evidence-of-selection-on-splicing-associated-loci-in-human-populations-and-relevance-to-disease-loci-mapping
#16
Eric R Gamazon, Anuar Konkashbaev, Eske M Derks, Nancy J Cox, Younghee Lee
We performed a whole-genome scan of genetic variants in splicing regulatory elements (SREs) and evaluated the extent to which natural selection has shaped extant patterns of variation in SREs. We investigated the degree of differentiation of single nucleotide polymorphisms (SNPs) in SREs among human populations and applied long-range haplotype- and multilocus allelic differentiation-based methods to detect selection signatures. We describe an approach, sampling a large number of loci across the genome from functional classes and using the consensus from multiple tests, for identifying candidates for selection signals...
July 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28729716/pharmacogenetic-comparison-of-cyp2d6-predictive-and-measured-phenotypes-in-a-south-african-cohort
#17
T M Dodgen, C De J Labuschagne, A van Schalkwyk, F E Steffens, A Gaedigk, A D Cromarty, M Alessandrini, M S Pepper
This corrects the article DOI: 10.1038/tpj.2015.76.
July 2017: Pharmacogenomics Journal
https://www.readbyqxmd.com/read/28729474/trilateral-overlap-of-tuberculosis-diabetes-and-hiv-1-in-a-high-burden-african-setting-implications-for-tb-control
#18
Tolu Oni, Natacha Berkowitz, Mmamapudi Kubjane, Rene Goliath, Naomi S Levitt, Robert J Wilkinson
The diabetes mellitus burden is growing in countries where tuberculosis (TB) and HIV-1 remain major challenges, threatening TB control efforts. This study determined the association between TB and diabetes/impaired glucose regulation in the context of HIV-1.A cross-sectional study was conducted at a TB clinic in Cape Town (South Africa). Participants were screened for diabetes and impaired glucose regulation using fasting plasma glucose, oral glucose tolerance test and glycated haemoglobin (HbA1c).414 TB and 438 non-TB participants were enrolled...
July 2017: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
https://www.readbyqxmd.com/read/28729309/the-role-of-a-decision-support-smartphone-application-in-enhancing-community-health-volunteers-effectiveness-to-improve-maternal-and-newborn-outcomes-in-nairobi-kenya-quasi-experimental-research-protocol
#19
Pauline Bakibinga, Eva Kamande, Milka Omuya, Abdhalah K Ziraba, Catherine Kyobutungi
INTRODUCTION: Improving maternal and newborn survival remains major aspirations for many countries in the Global South. Slum settlements, a result of rapid urbanisation in many developing countries including Kenya, exhibit high levels of maternal and neonatal mortality. There are limited referral mechanisms for sick neonates and their mothers from the community to healthcare facilities with ability to provide adequate care. In this study, we specifically plan to develop and assess the added value of having community health volunteers (CHVs) use smartphones to identify and track mothers and children in a bid to reduce pregnancy-related complications and newborn deaths in the urban slums of Kamukunji subcounty in Nairobi, Kenya...
July 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/28729127/variation-in-safe-sleep-and-breastfeeding-practices-among-non-hispanic-black-mothers-in-the-us-according-to-birth-country
#20
Margaret G K Parker, Eve R Colson, Lauren Provini, Denis V Rybin, Stephen M Kerr, Timothy Heeren, Michael J Corwin
OBJECTIVE: To examine variation in safe sleep and breastfeeding practices among US non-Hispanic black (NHB) mothers according to birth country METHODS: We analyzed NHB mothers that were surveyed regarding safe sleep and breastfeeding practices when their infants were 2-6 months of age in 2011-14, as part of a larger national study. We examined prevalences of safe sleep and breastfeeding practices according to birth country and examined odds of adherence to American Academy of Pediatrics recommended safe sleep and breastfeeding practices in foreign born NHBs, compared to US born NHBs...
July 17, 2017: Academic Pediatrics
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