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Clinical informatics

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https://www.readbyqxmd.com/read/28535206/clinical-exome-sequencing-reports-current-informatics-practice-and-future-opportunities
#1
Rajeswari Swaminathan, Yungui Huang, Caroline Astbury, Sara Fitzgerald-Butt, Katherine Miller, Justin Cole, Christopher Bartlett, Simon Lin
The increased adoption of clinical whole exome sequencing (WES) has improved the diagnostic yield for patients with complex genetic conditions. However, the informatics practice for handling information contained in whole exome reports is still in its infancy, as evidenced by the lack of a common vocabulary within clinical sequencing reports generated across genetic laboratories. Genetic testing results are mostly transmitted using portable document format, which can make secondary analysis and data extraction challenging...
May 23, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28527497/informatics-and-technology-in-resident-education
#2
REVIEW
William Niehaus
Biomedical or clinical informatics is the transdisciplinary field that studies and develops effective uses of biomedical data, information technology innovations, and medical knowledge for scientific inquiry, problem solving, and decision making, with an emphasis on improving human health. Given the ongoing advances in information technology, the field of informatics is becoming important to clinical practice and to residency education. This article will discuss how informatics is specifically relevant to residency education and the different ways to incorporate informatics into residency education, and will highlight applications of current technology in the context of residency education...
May 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28527494/clinical-informatics-in-physiatry
#3
EDITORIAL
Mark E Huang
No abstract text is available yet for this article.
May 2017: PM & R: the Journal of Injury, Function, and Rehabilitation
https://www.readbyqxmd.com/read/28523205/2016-year-in-review-of-clinical-and-consumer-informatics-analysis-and-visualization-of-keywords-and-topics
#4
REVIEW
Hyeoun-Ae Park, Joo Yun Lee, Jeongah On, Ji Hyun Lee, Hyesil Jung, Seul Ki Park
OBJECTIVES: The objective of this study was to review and visualize the medical informatics field over the previous 12 months according to the frequencies of keywords and topics in papers published in the top four journals in the field and in Healthcare Informatics Research (HIR), an official journal of the Korean Society of Medical Informatics. METHODS: A six-person team conducted an extensive review of the literature on clinical and consumer informatics. The literature was searched using keywords employed in the American Medical Informatics Association year-in-review process and organized into 14 topics used in that process...
April 2017: Healthcare Informatics Research
https://www.readbyqxmd.com/read/28508816/physicians-use-of-online-clinical-evidence-in-mashhad-university-of-medical-sciences-iran
#5
Masoumeh Sarbaz, Khalil Kimiafar, Alireza Banaye Yazdipour
The Internet is an important source of medical information. It is expected that the use of online sources will improve clinical decisions. This study aims to evaluate online information seeking behavior of physicians of Mashhad University of Medical Sciences on the use of online clinical evidence. A cross-sectional, questionnaire-based study was carried out between November and December 2014 in the five academic hospitals. A total of 252 physicians completed the questionnaire. The majority of physicians (63...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28508782/the-use-of-restful-web-services-in-medical-informatics-and-clinical-research-and-its-implementation-in-europe
#6
Jozef Aerts
BACKGROUND: RESTful web services nowadays are state-of-the-art in business transactions over the internet. They are however not very much used in medical informatics and in clinical research, especially not in Europe. OBJECTIVES: To make an inventory of RESTful web services that can be used in medical informatics and clinical research, including those that can help in patient empowerment in the DACH region and in Europe, and to develop some new RESTful web services for use in clinical research and regulatory review...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28495862/the-diagnosis-wide-landscape-of-hospital-acquired-aki
#7
Anne-Sophie Jannot, Anita Burgun, Eric Thervet, Nicolas Pallet
BACKGROUND AND OBJECTIVES: The exploration of electronic hospital records offers a unique opportunity to describe in-depth the prevalence of conditions associated with diagnoses at an unprecedented level of comprehensiveness. We used a diagnosis-wide approach, adapted from phenome-wide association studies (PheWAS), to perform an exhaustive analysis of all diagnoses associated with hospital-acquired AKI (HA-AKI) in a French urban tertiary academic hospital over a period of 10 years. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We retrospectively extracted all diagnoses from an i2b2 (Informatics for Integrating Biology and the Bedside) clinical data warehouse for patients who stayed in this hospital between 2006 and 2015 and had at least two plasma creatinine measurements performed during the first week of their stay...
May 11, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28495345/the-georges-pompidou-university-hospital-clinical-data-warehouse-a-8-years-follow-up-experience
#8
Anne-Sophie Jannot, Eric Zapletal, Paul Avillach, Marie-France Mamzer, Anita Burgun, Patrice Degoulet
BACKGROUND: When developed jointly with clinical information systems, clinical data warehouses (CDWs) facilitate the reuse of healthcare data and leverage clinical research. OBJECTIVE: To describe both data access and use for clinical research, epidemiology and health service research of the "Hôpital Européen Georges Pompidou" (HEGP) CDW. METHODS: The CDW has been developed since 2008 using an i2b2 platform. It was made available to health professionals and researchers in October 2010...
June 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28494382/a-computer-supported-management-of-photographic-documentation-in-plastic-surgery-system-development-and-its-clinical-application
#9
Karol Korczak, Anna Kasielska-Trojan, Marian Niedźwiedziński, Bogusław Antoszewski
Photographic documentation is very important for plastic, reconstructive, and especially aesthetic surgery procedures. It can be used to improve patient care as well as to carry out scientific research. The results of our previous studies confirmed a strong demand for Information Technology (IT) systems dedicated to plastic surgery. Unfortunately, most of the solutions of this type are not suited to the actual needs. For this reason we decided to develop a reliable system for photographic documentation storage...
May 3, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/28480479/historical-roots-of-international-biomedical-and-health-informatics-the-road-to-ifip-tc4-and-imia-through-cybernetic-medicine-and-the-elsinore-meetings
#10
C A Kulikowski
BACKGROUND: It is 50 years since the International Federation of Information Processing (IFIP) Societies approved the formation of a new Technical Committee (TC) 4 on Medical Information Processing under the leadership of Professor Francois Grémy, which was the direct precursor of the International Medical Informatics Association (IMIA). OBJECTIVES: The goals of this paper are to give a very brief overview of early international developments leading to informatics in medicine, with the origins of the applications of computers to medicine in the USA and Europe, and two meetings - of the International Society of Cybernetic Medicine, and the Elsinore Meetings on Hospital Information Systems - that took place in 1966...
May 8, 2017: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/28480477/evaluation-considerations-for-secondary-uses-of-clinical-data-principles-for-an-evidence-based-approach-to-policy-and-implementation-of-secondary-analysis-a-position-paper-from-the-imia-technology-assessment-quality-development-in-health-informatics-working
#11
P J Scott, M Rigby, E Ammenwerth, J Brender McNair, A Georgiou, H Hyppönen, N de Keizer, F Magrabi, P Nykänen, W T Gude, W Hackl
OBJECTIVES: To set the scientific context and then suggest principles for an evidence-based approach to secondary uses of clinical data, covering both evaluation of the secondary uses of data and evaluation of health systems and services based upon secondary uses of data. METHOD: Working Group review of selected literature and policy approaches. RESULTS: We present important considerations in the evaluation of secondary uses of clinical data from the angles of governance and trust, theory, semantics, and policy...
May 8, 2017: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/28480474/secondary-use-and-analysis-of-big-data-collected-for-patient-care-contribution-from-the-imia-working-group-on-data-mining-and-big-data-analytics
#12
F J Martin-Sanchez, V Aguiar-Pulido, G H Lopez-Campos, N Peek, L Sacchi
OBJECTIVES: To identify common methodological challenges and review relevant initiatives related to the re-use of patient data collected in routine clinical care, as well as to analyze the economic benefits derived from the secondary use of this data. Through the use of several examples, this article aims to provide a glimpse into the different areas of application, namely clinical research, genomic research, study of environmental factors, and population and health services research...
May 8, 2017: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/28480473/the-imia-history-working-group-inception-through-the-imia-history-taskforce-and-major-events-leading-up-to-the-50th-anniversary-of-imia
#13
C A Kulikowski, G Mihalas, R A Greenes, V Yacubsohn, H-A Park
BACKGROUND: The 50th Anniversary of IMIA will be celebrated in 2017 at the World Congress of Medical Informatics in China. This takes place 50 years after the International Federation of Information Processing (IFIP) Societies approved the formation of a new Technical Committee (TC) 4 on Medical Information Processing, which was the predecessor of IMIA, under the leadership of Dr. Francois Grémy. The IMIA History Working Group (WG) was approved in 2014 to document and write about the history of the field and its organizations...
May 8, 2017: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/28480472/added-value-from-secondary-use-of-person-generated-health-data-in-consumer-health-informatics-contribution-of-the-consumer-health-informatics-imia-working-group
#14
P-Y Hsueh, Y-K Cheung, S Dey, K K Kim, F J Martin-Sanchez, S K Petersen, T Wetter
INTRODUCTION: Various health-related data, subsequently called Person Generated Health Data (PGHD), is being collected by patients or presumably healthy individuals as well as about them as much as they become available as measurable properties in their work, home, and other environments. Despite that such data was originally just collected and used for dedicated predefined purposes, more recently it is regarded as untapped resources that call for secondary use. METHOD: Since the secondary use of PGHD is still at its early evolving stage, we have chosen, in this paper, to produce an outline of best practices, as opposed to a systematic review...
May 8, 2017: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/28480470/on-contributing-to-the-progress-of-medical-informatics-as-publisher-congratulations-to-imia-honorary-fellow-dieter-bergemann-on-his-80th-birthday
#15
R Haux, A Geissbuhler, J Holmes, M-C Jaulent, S Koch, C A Kulikowski, C U Lehmann, A T McCray, B Séroussi, L F Soualmia, J H van Bemmel
May 1st, 2017, will mark Dieter Bergemann's 80th birthday. As Chief Executive Officer and Owner of Schattauer Publishers from 1983 to 2016, the biomedical and health informatics community owes him a great debt of gratitude. The past and present editors of Methods of Information in Medicine, the IMIA Yearbook of Medical Informatics, and Applied Clinical Informatics want to honour and thank Dieter Bergemann by providing a brief biography that emphasizes his contributions, by reviewing his critical role as an exceptionally supportive publisher for Schattauer's three biomedical and health informatics periodicals, and by sharing some personal anecdotes...
May 8, 2017: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/28478747/creation-of-a-virtual-antidotes-network-between-pharmacy-departments-of-catalan-hospitals
#16
Raquel Aguilar-Salmerón, Edurne Fernández de Gamarra-Martínez, Milagros García-Peláez, Antoni Broto-Sumalla, Lidia Martínez-Sánchez, Santiago Nogué-Xarau
Objetive: To design a virtual antidote network between hospitals that could help to locate on-line those hospitals that stocked those antidotes with the highest difficulty in terms of availability, and ensured that the medication was loaned in case of necessity. METHODS: The application was developed by four hospital pharmacists and two clinical toxicologists with the support of a Healthcare Informatics Consultant Company. RESULTS: The antidotes network in Catalonia, Spain, was launched in July 2015...
May 1, 2017: Farmacia Hospitalaria
https://www.readbyqxmd.com/read/28473971/design-and-implementation-of-the-hepatorenal-fibrocystic-disease-core-center-clinical-database-a-centralized-resource-for-characterizing-autosomal-recessive-polycystic-kidney-disease-and-other-hepatorenal-fibrocystic-diseases
#17
Bakri Alzarka, Hiroki Morizono, John W Bollman, Dongkyu Kim, Lisa M Guay-Woodford
Autosomal recessive polycystic kidney disease (ARPKD) and other hepatorenal fibrocystic diseases (HRFD) are relatively rare recessive disorders that constitute an important set of childhood nephropathies. Little is known about fundamental pathogenesis, and advances toward clinical trials will require well-characterized patient cohorts and the development of predictive and prognostic biomarkers. Such studies in rare diseases require greater collaboration than the efforts in common diseases where large patient repositories can be built at a single site...
2017: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/28472359/constructing-the-informatics-and-information-technology-foundations-of-a-medical-device-evaluation-system-a-report-from-the-fda-unique-device-identifier-demonstration
#18
Joseph P Drozda, James Roach, Thomas Forsyth, Paul Helmering, Benjamin Dummitt, James E Tcheng
Objective: The US Food and Drug Administration (FDA) has recognized the need to improve the tracking of medical device safety and performance, with implementation of Unique Device Identifiers (UDIs) in electronic health information as a key strategy. The FDA funded a demonstration by Mercy Health wherein prototype UDIs were incorporated into its electronic information systems. This report describes the demonstration's informatics architecture. Methods: Prototype UDIs for coronary stents were created and implemented across a series of information systems, resulting in UDI-associated data flow from manufacture through point of use to long-term follow-up, with barcode scanning linking clinical data with UDI-associated device attributes...
May 3, 2017: Journal of the American Medical Informatics Association: JAMIA
https://www.readbyqxmd.com/read/28470962/do-patients-have-worse-outcomes-in-heart-failure-than-in-cancer-a-primary-care-based-cohort-study-with-10-year-follow-up-in-scotland
#19
Mamas A Mamas, Matthew Sperrin, Margaret C Watson, Alasdair Coutts, Katie Wilde, Christopher Burton, Umesh T Kadam, Chun Shing Kwok, Allan B Clark, Peter Murchie, Iain Buchan, Philip C Hannaford, Phyo K Myint
AIMS: This study was designed to evaluate whether survival rates in patients with heart failure (HF) are better than those in patients with diagnoses of the four most common cancers in men and women, respectively, in a contemporary primary care cohort in the community in Scotland. METHODS AND RESULTS: Data were obtained from the Primary Care Clinical Informatics Unit from a database of 1.75 million people registered with 393 general practices in Scotland. Sex-specific survival modelling was undertaken using Cox proportional hazards models, adjusted for potential confounders...
May 3, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28469432/systematic-review-of-medical-informatics-supported-medication-decision-making
#20
REVIEW
Brittany L Melton
This systematic review sought to assess the applications and implications of current medical informatics-based decision support systems related to medication prescribing and use. Studies published between January 2006 and July 2016 which were indexed in PubMed and written in English were reviewed, and 39 studies were ultimately included. Most of the studies looked at computerized provider order entry or clinical decision support systems. Most studies examined decision support systems as a means of reducing errors or risk, particularly associated with medication prescribing, whereas a few studies evaluated the impact medical informatics-based decision support systems have on workflow or operations efficiency...
2017: Biomedical Informatics Insights
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