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https://www.readbyqxmd.com/read/28737681/nutrient-and-total-polyphenol-contents-of-dark-green-leafy-vegetables-and-estimation-of-their-iron-bioaccessibility-using-the-in-vitro-digestion-caco-2-cell-model
#1
Francis Kweku Amagloh, Richard Atinpoore Atuna, Richard McBride, Edward Ewing Carey, Tatiana Christides
Dark green leafy vegetables (DGLVs) are considered as important sources of iron and vitamin A. However, iron concentration may not indicate bioaccessibility. The objectives of this study were to compare the nutrient content and iron bioaccessibility of five sweet potato cultivars, including three orange-fleshed types, with other commonly consumed DGLVs in Ghana: cocoyam, corchorus, baobab, kenaf and moringa, using the in vitro digestion/Caco-2 cell model. Moringa had the highest numbers of iron absorption enhancers on an "as-would-be-eaten" basis, β-carotene (14169 μg/100 g; p < 0...
July 22, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/28717307/traditional-treatment-of-human-and-animal-salmonelloses-in-southern-benin-knowledge-of-farmers-and-traditherapists
#2
T V Dougnon, E Déguénon, L Fah, B Lègba, Y M G Hounmanou, J Agbankpè, A Amadou, H Koudokpon, K Fabiyi, A Aniambossou, P Assogba, E Hounsa, M de Souza, F Avlessi, T J Dougnon, F Gbaguidi, M Boko, H S Bankolé, L Baba-Moussa
AIM: This study aimed to report medicinal plants that are likely to be used in the control of salmonellosis. MATERIALS AND METHODS: A cross-sectional study was conducted in Southern Benin. Semi-structured questionnaires were administered to 150 farmers and 100 traditional therapists in seven high municipalities. This step helped to collect plants that are used in the treatment of animal salmonellosis and typhoid fever in human. RESULTS: The results revealed a low level of use of medicinal plants among breeders who prefer antibiotics such as oxytetracycline (53...
June 2017: Veterinary World
https://www.readbyqxmd.com/read/28713487/moringa-oleifera-seeds-attenuate-vascular-oxidative-and-nitrosative-stresses-in-spontaneously-hypertensive-rats
#3
Joseph Iharinjaka Randriamboavonjy, Marc Rio, Pierre Pacaud, Gervaise Loirand, Angela Tesse
Moringa oleifera (MOI) is a tree currently used in traditional medicine in tropical Africa, America, and Asia for therapeutic applications in several disorders including arterial hypertension. We previously described a cardiac protective role of a treatment with MOI seeds in spontaneously hypertensive rats (SHR). Here, we investigated the effects of this treatment on oxidative and nitrosative vascular stresses in SHR, with normotensive Wistar Kyoto rats used as controls. Oxidative and nitrosative stresses detected in SHR aortas using the fluorescent dye dihydroethidine and protein nitrotyrosine staining were reduced in MOI-treated SHR aortas...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/28705212/moringa-isothiocyanate-complexed-with-%C3%AE-cyclodextrin-a-new-perspective-in-neuroblastoma-treatment
#4
Sabrina Giacoppo, Renato Iori, Patrick Rollin, Placido Bramanti, Emanuela Mazzon
BACKGROUND: Several lines of evidence suggest the consume of natural products for cancer prevention or treatment. In particular, isothiocyanates (ITCs) exerting anti-cancer properties, have received great interest as potential chemotherapeutic agents. This study was designed to assess the anti-proliferative activities of a new preparation of Moringa oleifera-derived 4-(α-L-rhamnopyranosyloxy)benzyl ITC (moringin) complexed with alpha-cyclodextrin (moringin + α-CD; MAC) on SH-SY5Y human neuroblastoma cells...
July 14, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28692885/ecotoxicity-of-water-soluble-lectin-from-moringa-oleifera-seeds-to-zebrafish-danio-rerio-embryos-and-larvae
#5
Livia Lais de Santana Silva, Romulo Nepomuceno Alves, Driele Ventura de Paulo, José Dayvid Ferreira da Silva, Ana Patrícia Silva de Oliveira, Luana Cassandra Breitenbach Barroso Coelho, Daniela Maria do Amaral Ferraz Navarro, Thiago Henrique Napoleão, Ian Porto Gurgel do Amaral, Paulo Sérgio Martins de Carvalho, Patrícia Maria Guedes Paiva
The evaluation of ecotoxicity of mosquito larvicidal agents (such as the water-soluble lectin from Moringa oleifera seeds, WSMoL) is an essential step to establish the guidelines for their use. In this sense, this work evaluated the toxicity of WSMoL to Danio rerio embryos and larvae. Embryos were exposed to waterborne WSMoL (0.0125-0.2 mg mL(-1)) for 96 h and lethal and sub-lethal effects were observed every 24 h. In the bioassays with larvae, the individuals were exposed to the WSMoL (0.025-0.2 mg mL(-1)), mortality was recorded daily, and larval swimming velocities were analyzed after 72 h and 168 h of exposure...
July 5, 2017: Chemosphere
https://www.readbyqxmd.com/read/28684924/diuretic-activity-of-the-aqueous-crude-extract-and-hot-tea-infusion-of-moringa-stenopetala-baker-f-cufod-leaves-in-rats
#6
Netsanet Fekadu, Hirut Basha, Asfaw Meresa, Sileshi Degu, Biruktawit Girma, Bekesho Geleta
Moringa stenopetala (Baker f.) Cufod. is a medicinal plant that has been used for the treatment of different ailments such as hypertension and diabetes in Ethiopia. This study aims to assess the diuretic activity of the aqueous crude extract and hot tea infusion of M. stenopetala leaves in saline-loaded rats. Male Wistar rats were divided into ten groups (n = 5). The control group received distilled water (5 mL/kg), whereas the reference group received Furosemide (10 mg/kg). Groups III-X orally received different doses of aqueous crude extract (62...
2017: Journal of Experimental Pharmacology
https://www.readbyqxmd.com/read/28665513/effects-of-feeding-a-moringa-oleifera-rachis-and-twig-preparation-to-dairy-cows-on-their-milk-production-and-fatty-acid-composition-and-plasma-antioxidants
#7
Tingting Zhang, Bingwen Si, Kaidong Deng, Yan Tu, Chaolong Zhou, Qiyu Diao
BACKGROUND: We determined how supplementing the diet of lactating, multiparous Holstein dairy cows with a preparation of Moringa oleifera rachises and twigs affected their milk production and quality and the levels of plasma antioxidants. RESULTS: We found that milk yield increased in cows receiving the 6% (w/w) moringa supplement compared with that of the control. Addition of the moringa supplement increased the concentration of milk fat and decreased the somatic cell count in the milk...
June 30, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28645635/cytotoxicity-of-the-coagulant-moringa-oleifera-lectin-cmol-to-b16-f10-melanoma-cells
#8
Luciana de Andrade Luz, Franco Aparecido Rossato, Rute Alves Pereira E Costa, Thiago Henrique Napoleão, Patrícia Maria Guedes Paiva, Luana Cassandra Breitenbach Barroso Coelho
Moringa oleifera seeds are used in alternative medicine to treat inflammation, tumors and bacterial and protozoan infections, for example. The seeds contain lectins, which are carbohydrate-binding proteins with several biological properties including cytotoxicity to cancer cells. In this work, we examined the cytotoxicity of the coagulant M. oleifera lectin (cMoL) on B16-F10 murine melanoma cells. cMoL cytotoxic effects were evaluated through trypan blue assay and flow cytometry analysis. Mitochondrial superoxide levels and activation of caspases 3, 8 and 9 were measured...
June 20, 2017: Toxicology in Vitro: An International Journal Published in Association with BIBRA
https://www.readbyqxmd.com/read/28641022/a-randomized-single-dose-parallel-study-on-enhancement-of-nitric-oxide-in-serum-and-saliva-with-the-use-of-natural-sports-supplement-in-healthy-adults
#9
Joby Jacob, Sreeraj Gopi, Chandradhara Divya
Sports supplements that stimulate the production of nitric oxide (NO) are widely promoted agents in the sports nutrition domain, and nitric oxide plays an important role to enhance the cardiovascular and physical fitness of the sports participants. The purpose of the study is to investigate whether oral intake of a sports nutritional supplement (Fitnox) is able to increase nitrate (NO3(-)) and nitrite (NO2(-)) levels in blood serum and saliva of healthy adults. Fitnox is a unique blend of Kaempferia parviflora methoxy flavones, pomegranate peel polyphenols, and Moringa oleifera leaf saponins...
June 22, 2017: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/28640194/moringa-leaves-prevent-hepatic-lipid-accumulation-and-inflammation-in-guinea-pigs-by-reducing-the-expression-of-genes-involved-in-lipid-metabolism
#10
Manal Mused Almatrafi, Marcela Vergara-Jimenez, Ana Gabriela Murillo, Gregory H Norris, Christopher N Blesso, Maria Luz Fernandez
To investigate the mechanisms by which Moringa oleifera leaves (ML) modulate hepatic lipids, guinea pigs were allocated to either control (0% ML), 10% Low Moringa (LM) or 15% High Moringa (HM) diets with 0.25% dietary cholesterol to induce hepatic steatosis. After 6 weeks, guinea pigs were sacrificed and liver and plasma were collected to determine plasma lipids, hepatic lipids, cytokines and the expression of genes involved in hepatic cholesterol (CH) and triglyceride (TG) metabolism. There were no differences in plasma lipids among groups...
June 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28634471/a-chitin-binding-protein-purified-from-moringa-oleifera-seeds-presents-anticandidal-activity-by-increasing-cell-membrane-permeability-and-reactive-oxygen-species-production
#11
João X S Neto, Mirella L Pereira, Jose T A Oliveira, Lady C B Rocha-Bezerra, Tiago D P Lopes, Helen P S Costa, Daniele O B Sousa, Bruno A M Rocha, Thalles B Grangeiro, José E C Freire, Ana Cristina O Monteiro-Moreira, Marina D P Lobo, Raimunda S N Brilhante, Ilka M Vasconcelos
Candida species are opportunistic pathogens that infect immunocompromised and/or immunosuppressed patients, particularly in hospital facilities, that besides representing a significant threat to health increase the risk of mortality. Apart from echinocandins and triazoles, which are well tolerated, most of the antifungal drugs used for candidiasis treatment can cause side effects and lead to the development of resistant strains. A promising alternative to the conventional treatments is the use of plant proteins...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28630394/moringa-oleifera-based-diet-protects-against-nickel-induced-hepatotoxicity-in-rats
#12
Stephen Adeyemi Oluyomi, Sokolayemji Aroge Cincin, Adewumi Akanji Musbau
Multiple health-promoting effects have been attributed to the consumption of Moringa oleifera leaves, as part of diet without adequate scientific credence. This study evaluated the effect of M. oleifera-based diets on nickel (Ni) - induced hepatotoxicity in rats. Male rats assigned into six groups were given oral administration of 20 mg/kg body weight nickel sulfate in normal saline and either fed normal diet or M. oleifera-based diets for 21 days. All animals were sacrificed under anesthesia 24 hours after the last treatment...
June 20, 2017: Journal of Biomedical Research
https://www.readbyqxmd.com/read/28627054/effect-of-moringa-oleifera-leaf-powder-supplementation-on-growth-performance-and-intestinal-morphology-in-broiler-chickens
#13
I Khan, H Zaneb, S Masood, M S Yousaf, H F Rehman, H Rehman
Due to public health hazards of subtherapeutic use of antibiotics in poultry feed, there is a need for alternatives. Moringa oleifera is a phytobiotic, which is reported to possess antimicrobial and immuno-modulatory properties. This study aimed to investigate effects of M. oleifera leaf powder (MOLP) supplementation on growth performance and intestinal microarchitecture of broiler chickens. Day-old broiler chicks (n = 100) were randomly divided into five groups with four replicates each having five birds...
June 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28603877/effects-of-moringa%C3%A2-oleifera-leaves-as-a-substitute-for-alfalfa-meal-on-nutrient-digestibility-growth-performance-carcass-trait-meat-quality-antioxidant-capacity-and-biochemical-parameters-of-rabbits
#14
B Sun, Y Zhang, M Ding, Q Xi, G Liu, Y Li, D Liu, X Chen
This contribution reports the effects of Moringa oleifera leaves (MOLs) meal on the growth performances, nutrient digestibility, carcass trait, meat quality, antioxidant capacity and biochemical parameters of growing New Zealand white rabbits. The MOL was substituted for alfalfa meal at levels of 0, 10%, 20% and 30% to obtain respective diets MOL0, MOL10, MOL20 and MOL30. Each treatment was replicated five times with 10 rabbits per replicate. Results showed the average daily weight gain (ADWG) and feed conversion ratio (FCR) of rabbits fed MOL20 diet were significantly better (p < 0...
June 12, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/28585494/recombinant-protein-expression-of-moringa-oleifera-lectin-in-methylotrophic-yeast-as-active-coagulant-for-sustainable-high-turbid-water-treatment
#15
Muhamad Azhar Abd Wahid, Megat Johari Megat Mohd Noor, Masafumi Goto, Norio Sugiura, Nor'azizi Othman, Zuriati Zakaria, Thamer Ahmad Mohammed, Ahmad Jusoh, Hirofumi Hara
The natural coagulant Moringa oleifera lectin (MoL) as cationic protein is a promising candidate in coagulation process of water treatment plant. Introducing the gene encoding MoL into a host, Pichia pastoris, to secrete soluble recombinant protein is assessed in this study. Initial screening using PCR confirmed the insertion of MoL gene, and SDS-PAGE analysis detected the MoL protein at 8 kDa. Cultured optimization showed the highest MoL protein at 520 mg/L was observed at 28 °C for 144 h of culturing by induction in 1% methanol...
June 6, 2017: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/28573245/antiproliferative-effect-on-breast-cancer-mcf7-of-moringa-oleifera-seed-extracts
#16
Ismail Abiola Adebayo, Hasni Arsad, Mohd Razip Samian
BACKGROUND: Moringa oleifera belongs to plant family, Moringaceae and popularly called "wonderful tree", for it is used traditionally to cure many diseases including cancer in Africa and Asia, however, there is limited knowledge on cytotoxic activity of Moringa oleifera seeds on MCF7 breast cancer cell. The present study evaluated antiproliferative effect on MCF7 of the seed. MATERIALS AND METHODS: Seeds of Moringa oleifera were grinded to powder and its phytochemicals were extracted using water and 80% ethanol solvents, part of the ethanolic extract were sequentially partitioned to fractions with four solvents (hexane, dichloromethane, chloroform, and n-butanol)...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28573237/protective-effect-of-moringa-peregrina-leaves-extract-on-acetaminophen-induced-liver-toxicity-in-albino-rats
#17
Samy Abdelfatah Abdel Azim, Mohamed Taha Abdelrahem, Mostafa Mohamed Said, Alshaimaa Khattab
BACKGROUND: Acetaminophen is a common antipyretic drug but at overdose can cause severe hepatotoxicity that may further develop into liver failure and hepatic centrilobular necrosis in experimental animals and humans. This study was undertaken to assess the ameliorative role of Moringa peregrina leaves extract against acetaminophen toxicity in rats. MATERIALS AND METHODS: Induction of hepatotoxicity was done by chronic oral administration of acetaminophen (750 mg/kg bwt) for 4 weeks...
2017: African Journal of Traditional, Complementary, and Alternative Medicines: AJTCAM
https://www.readbyqxmd.com/read/28571135/moringa-oleifera-leaf-extract-beneficial-effects-on-cadmium-induced-toxicities-a-review
#18
REVIEW
Roopashree Mallya, Pratik Kumar Chatterjee, N A Vinodini, Poulomi Chatterjee, Prasanna Mithra
Environment has been contaminated by heavy metals ever since the original magma of earth has solidified. One such toxin is cadmium. Cadmium that has been around since the industrial age, is considered hazardous both to us and to the environment. From time immemorial man is dependent on plants available in nature for several health benefits. Moringa oleifera, has nutritional, pharmacological and antioxidant properties, thus having several medicinal applications. In the present article, we discuss the dose and time dependent damage due to exposure to cadmium on kidneys, liver, testis, lipid profile and haematological parameters in adult Wistar rats and the protective effects of Moringa oleifera (pre-treatment) on cadmium induced damage...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28557705/moringa-olifeira-lam-stimulates-activation-of-the-insulin-dependent-akt-pathway-antidiabetic-effect-in-a-diet-induced-obesity-dio-mouse-model
#19
E S Attakpa, M M Sangaré, G J Béhanzin, J-M Ategbo, B Seri, N A Khan
We investigated the antidiabetic effect of Moringa olifeira Lam. in a diet-induced obesity (DIO) mouse model. Six mice were randomly selected as normal controls. Moringa olifeira Lam. leaf extract at a dose of 200, 400 or 600 mg/kg body weight, glibenclamide (Glib) at the dose of 10 mg/kg (positive control) and distilled water at 10 ml/kg (control group) were administered orally by gastric intubation, and each group consisted of six mice. Insulinsensitive tissues (liver, skeletal muscle) were collected to investigate antidiabetic effects and examine the plant's molecular mechanisms...
2017: Folia Biologica (Praha)
https://www.readbyqxmd.com/read/28554043/salt-induced-polystyrene-latex-flocs-investigated-by-neutron-scattering
#20
Habauka M Kwaambwa, Maja S Hellsing, Matthew J Wasbrough, Markus Bleuel, Adrian R Rennie
Studies with a model system consisting of polystyrene latex particles showed that the protein from seeds of Moringa trees adsorbs to the surface and causes flocculation as unusually dense aggregates. In this study, electrolytes sodium chloride (NaCl), ferric chloride (FeCl3) and aluminium sulfate (Al2(SO4)3) have been used to aggregate model polystyrene particles. The study augments previous work using neutron scattering on the flocculation of polystyrene latex with protein from seeds of Moringa trees that had indicated higher floc dimension, df, values as the concentration of particles increased...
May 17, 2017: Journal of Colloid and Interface Science
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