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Vitamin B6

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https://www.readbyqxmd.com/read/28212289/the-effects-of-myo-inositol-and-b-and-d-vitamin-supplementation-in-the-db-mouse-model-of-gestational-diabetes-mellitus
#1
Jasmine F Plows, Florence Budin, Rebecka A M Andersson, Valerie J Mills, Katherine Mace, Sandra T Davidge, Mark H Vickers, Philip N Baker, Irma Silva-Zolezzi, Joanna L Stanley
Gestational diabetes mellitus (GDM) is a growing concern, affecting an increasing number of pregnant women worldwide. By predisposing both the affected mothers and children to future disease, GDM contributes to an intergenerational cycle of obesity and diabetes. In order to stop this cycle, safe and effective treatments for GDM are required. This study sought to determine the treatment effects of dietary supplementation with myo-inositol (MI) and vitamins B2, B6, B12, and D in a mouse model of GDM (pregnant db/+ dams)...
February 15, 2017: Nutrients
https://www.readbyqxmd.com/read/28202095/the-effects-of-vitamin-and-mineral-supplementation-on-symptoms-of-schizophrenia-a-systematic-review-and-meta-analysis
#2
J Firth, B Stubbs, J Sarris, S Rosenbaum, S Teasdale, M Berk, A R Yung
BACKGROUND: When used as an adjunctive with antipsychotics, certain vitamins and minerals may be effective for improving symptomatic outcomes of schizophrenia, by restoring nutritional deficits, reducing oxidative stress, or modulating neurological pathways. METHOD: We conducted a systematic review of all randomized controlled trials (RCTs) reporting effects of vitamin and/or mineral supplements on psychiatric symptoms in people with schizophrenia. Random-effects meta-analyses were used to calculate the standardized mean difference between nutrient and placebo treatments...
February 16, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28186698/added-dietary-vegetables-and-fruits-improved-coat-quality-of-capybara-in-seoul-zoo-republic-of-korea-a-case-study
#3
Hyungeun Shim, Ellen S Dierenfeld
Adequate levels of dietary vitamin C are necessary for capybaras (Hydrochoerus hydrocharis) because they cannot synthesize the vitamin endogenously. Beginning in 2013, hair and weight loss, as well as general dermatitis, were observed in all individual capybaras (n = 4) in a mixed exhibit at Seoul Zoo. Seven additional vegetables, leafy greens, and fruits that increased dietary vitamin C concentration from ∼300-400 to >600 mg/kg dry matter were added to the diet since January 2015. Within 6 months, capybaras' skin and coats improved considerably, with hair becoming thicker and glossier...
January 2017: Zoo Biology
https://www.readbyqxmd.com/read/28183371/regular-breakfast-consumption-is-associated-with-higher-blood-vitamin-status-in-adolescents-the-helena-healthy-lifestyle-in-europe-by-nutrition-in-adolescence-study
#4
Juan Mielgo-Ayuso, Jara Valtueña, Magdalena Cuenca-García, Fréderic Gottrand, Christina Breidenassel, Marika Ferrari, Yannis Manios, Stefaan De Henauw, Kurt Widhalm, Anthony Kafatos, Mathilde Kersting, Inge Huybrechts, Luis A Moreno, Marcela González-Gross
OBJECTIVE: The present study aimed to examine the association between different breakfast consumption patterns and vitamin intakes and blood vitamin concentrations in European adolescents. DESIGN: Breakfast consumption was assessed by a questionnaire. Vitamin intake was calculated from two 24 h recalls. Blood vitamin and total homocysteine (tHcy) concentrations were analysed from fasting blood samples. SETTING: The European Commission-funded HELENA (Healthy Lifestyle in Europe by Nutrition in Adolescence) Study...
February 10, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28182946/take-your-pick-vitamins-and-microbiota-facilitate-pathogen-clearance
#5
Vanessa Sperandio
The gut microbiota plays a chief role in vitamin production. Changes in its membership impact the gut metabolome and host susceptibility to pathogens. In this issue of Cell Host & Microbe, Miki et al. (2017) show that RegIIIβ impacts microbiota composition, decreasing vitamin B6 production and promoting sustained colonization by Salmonella.
February 8, 2017: Cell Host & Microbe
https://www.readbyqxmd.com/read/28178022/the-impact-of-essential-fatty-acid-b-vitamins-vitamin-c-magnesium-and-zinc-supplementation-on-stress-levels-in-women-a-systematic-review
#6
Delia McCabe, Karolina Lisy, Craig Lockwood, Marc Colbeck
BACKGROUND: Women juggling multiple roles in our complex society are increasingly experiencing psychological stress. Dietary supplementation to manage stress is widespread despite limited supporting evidence. A systematic review of the available literature was undertaken to investigate the efficacy of specific dietary supplements in managing female stress and anxiety. OBJECTIVES: To identify the impact of essential fatty acids (EFAs), B vitamins, vitamin C, magnesium and/or zinc, consumed as dietary supplements to the daily diet, on female stress and anxiety levels...
February 2017: JBI Database of Systematic Reviews and Implementation Reports
https://www.readbyqxmd.com/read/28176181/transthoracic-contrast-echocardiography-using-vitamin-b6-and-sodium-bicarbonate-as-contrast-agents-for-the-diagnosis-of-patent-foramen-ovale
#7
Jiang-Chun He, Jian-Yong Zheng, Xin Li, Ye Yang, Bo-Yang Zhang, Yu Chen, Xian-Feng Li, Ying-Ming Liu, Yi Cao, Li Zhao, Tian-Chang Li
To evaluate the utility of transthoracic contrast echocardiography (cTTE) using vitamin B6 and sodium bicarbonate as contrast agents for diagnosing right-to-left shunt (RLS) caused by patent foramen ovale (PFO) compared to that of transesophageal echocardiography (TEE). We investigated 125 patients admitted to our neurology department with unexplained cerebral infarction and migraine. All patients underwent cTTE using vitamin B6 and sodium bicarbonate as contrast agents, after which they underwent transthoracic echocardiography...
February 7, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28169875/vitamin-a-and-d-deficiencies-associated-with-incident-tuberculosis-in-hiv-infected-patients-initiating-antiretroviral-therapy-in-multinational-case-cohort-study
#8
Mark W Tenforde, Ashish Yadav, David W Dowdy, Nikhil Gupte, Rupak Shivakoti, Wei-Teng Yang, Noluthando Mwelase, Cecilia Kanyama, Sandy Pillay, Wadzanai Samaneka, Breno Santos, Selvamuthu Poongulali, Srikanth Tripathy, Cynthia Riviere, Sima Berendes, Javier R Lama, Sandra W Cardoso, Patcharaphan Sugandhavesa, Parul Christian, Richard D Semba, Thomas B Campbell, Amita Gupta
INTRODUCTION: Numerous micronutrients have immunomodulatory roles that may influence risk of tuberculosis (TB), but the association between baseline micronutrient deficiencies and incident TB after antiretroviral (ART) initiation in HIV-infected individuals is not well characterized. METHODS: We conducted a case-cohort study (n=332) within a randomized trial comparing three ART regimens in 1571 HIV treatment-naïve adults from nine countries. A subcohort of 30 patients was randomly selected from each country (n=270)...
February 6, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28161887/evaluation-of-vitamin-and-trace-element-requirements-after-sleeve-gastrectomy-at-long-term
#9
Silvia Pellitero, Eva Martínez, Rocío Puig, Alba Leis, Roxanna Zavala, María Luisa Granada, Cruz Pastor, Pau Moreno, Jordi Tarascó, Manel Puig-Domingo
BACKGROUND: Nutritional deficiencies are common after bariatric surgery, but data are scarce after sleeve gastrectomy (SG) at long term. METHODS: We performed a prospective nutritional status evaluation before and at 2 and 5 years after SG in morbid obese patients receiving mulvitamin and mineral supplementation at a Spanish university hospital. One hundred seventy-six patients (49.3 ± 9.1 years and 46.7 ± 7.4 kg/m(2)) were evaluated; 51 of them were followed during 5 years...
February 4, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28159823/serum-acylcarnitines-and-risk-of-cardiovascular-death-and-acute-myocardial-infarction-in-patients-with-stable-angina-pectoris
#10
Elin Strand, Eva R Pedersen, Gard F T Svingen, Thomas Olsen, Bodil Bjørndal, Therese Karlsson, Jutta Dierkes, Pål R Njølstad, Gunnar Mellgren, Grethe S Tell, Rolf K Berge, Asbjørn Svardal, Ottar Nygård
BACKGROUND: Excess levels of serum acylcarnitines, which are intermediate products in metabolism, have been observed in metabolic diseases such as type 2 diabetes mellitus. However, it is not known whether acylcarnitines may prospectively predict risk of cardiovascular death or acute myocardial infarction in patients with stable angina pectoris. METHODS AND RESULTS: This study included 4164 patients (median age, 62 years; 72% men). Baseline serum acetyl-, octanoyl-, palmitoyl-, propionyl-, and (iso)valerylcarnitine were measured using liquid chromatography/tandem mass spectrometry...
February 3, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28149510/breed-and-adaptive-response-modulate-bovine-peripheral-blood-cells-transcriptome
#11
Nataliya Pošćić, Tommaso Montanari, Mariasilvia D'Andrea, Danilo Licastro, Fabio Pilla, Paolo Ajmone-Marsan, Andrea Minuti, Sandy Sgorlon
BACKGROUND: Adaptive response includes a variety of physiological modifications to face changes in external or internal conditions and adapt to a new situation. The acute phase proteins (APPs) are reactants synthesized against environmental stimuli like stress, infection, inflammation. METHODS: To delineate the differences in molecular constituents of adaptive response to the environment we performed the whole-blood transcriptome analysis in Italian Holstein (IH) and Italian Simmental (IS) breeds...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/28143737/near-complete-correction-of-profound-metabolomic-impairments-corresponding-to-functional-benefit-in-mps-iiib-mice-after-iv-raav9-hnaglu-gene-delivery
#12
Haiyan Fu, Aaron S Meadows, Tierra Ware, Robert P Mohney, Douglas M McCarty
Mucopolysaccharidosis (MPS) IIIB is a lysosomal storage disease with complex CNS and somatic pathology due to a deficiency in α-N-acetylglucosaminidase (NAGLU). Using global metabolic profiling by mass spectrometry targeting 361 metabolites, this study detected significant decreases in 225 and increases in six metabolites in serum samples from 7-month-old MPS IIIB mice, compared to wild-type (WT) mice. The metabolic disturbances involve virtually all major pathways of amino acid, peptide (58/102), carbohydrate (18/28), lipid (111/139), nucleotide (12/24), energy (2/9), vitamin and cofactor (11/16), and xenobiotic (11/28) metabolism...
January 28, 2017: Molecular Therapy: the Journal of the American Society of Gene Therapy
https://www.readbyqxmd.com/read/28137367/genomic-health-status-assessed-by-a-cytokinesis-block-micronucleus-cytome-assay-in-a-healthy-middle-aged-korean-population
#13
Nan Young Cho, Kyung Woon Kim, Kyoung Kon Kim
The aim of this study was to determine the typical incidence of micronuclei (MNi) in the peripheral blood lymphocytes of healthy middle-aged Koreans using the cytokinesis-block micronucleus cytome (CBMN-Cyt) assay. Non-smoking, low-risk alcohol-drinking healthy Korean men and women aged 30 to 59 years were recruited. Participants were divided into three groups according to age, i.e., 30 to 39, 40 to 49, and 50 to 59 years. Fifty participants were included in each age group, for a total of 300 participants. DNA damage was measured based on the number of binucleated (BN) cells with MNi, nucleoplasmic bridges (NPBs), and nuclear buds (NBUDs) using the CBMN-Cyt assay...
February 2017: Mutation Research
https://www.readbyqxmd.com/read/28120854/fruit-and-vegetables-consumption-is-associated-with-higher-vitamin-intake-and-blood-vitamin-status-among-european-adolescents
#14
J Mielgo-Ayuso, J Valtueña, I Huybrechts, C Breidenassel, M Cuenca-García, S De Henauw, P Stehle, A Kafatos, M Kersting, K Widhalm, Y Manios, E Azzini, D Molnar, L A Moreno, M González-Gross
BACKGROUND/OBJECTIVES: Current research in adults indicates that fruit and vegetable (FAV) consumption increases serum levels of vitamins C, E and folate of β-carotene and reduces homocysteine concentrations. The aim of the present study was to examine the association of FAV consumption on vitamin intakes and their impact on blood vitamin concentrations in European adolescents. SUBJECT/METHODS: This multi-center cross-sectional study included 702 (53.7% females) adolescents, aged 12...
January 25, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28111202/the-bactericidal-lectin-regiii%C3%AE-prolongs-gut-colonization-and-enteropathy-in-the-streptomycin-mouse-model-for-salmonella-diarrhea
#15
Tsuyoshi Miki, Ryosuke Goto, Mayuka Fujimoto, Nobuhiko Okada, Wolf-Dietrich Hardt
The bactericidal lectin RegIIIβ is inducibly produced by intestinal epithelial cells as a defense against infection by enteropathogens. In the gut lumen, RegIIIβ kills not only certain enteropathogens, but also some commensal bacteria; thus, RegIIIβ is also thought to be an innate immune effector shaping microbiota composition and establishing intestinal homeostasis. Using the streptomycin mouse model for Salmonella colitis, we show that RegIIIβ can promote sustained gut colonization of Salmonella Typhimurium and prolong enteropathy...
February 8, 2017: Cell Host & Microbe
https://www.readbyqxmd.com/read/28109593/apparent-ruminal-synthesis-of-b-vitamins-in-lactating-dairy-cows-fed-diets-with-different-forage-to-concentrate-ratios
#16
M Seck, J A Voelker Linton, M S Allen, D S Castagnino, P Y Chouinard, C L Girard
Effects of the forage-to-concentrate ratio on apparent ruminal synthesis of thiamine, riboflavin, niacin, vitamin B6, folates, and vitamin B12 were evaluated in an experiment using 14 ruminally and duodenally cannulated Holstein cows. The experiment was a crossover design with two 15-d treatment periods and a 14-d preliminary period in which cows were fed a diet intermediate in composition between the treatment diets. Treatments were diets containing low-forage (44.8% forage, 32.8% starch, 24.4% neutral detergent fiber) or high-forage (61...
January 18, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28100326/-feeding-difficulty-and-developmental-delay-for-8-months-and-nystagmus-for-4-months-in-an-infant
#17
Jie Zhu, Fei Yu
Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare autosomal recessive hereditary disease and is a congenital metabolic disorder of neurotransmitter biosynthesis. It is mainly manifested as hypotonia, oculogyric crisis, autonomic dysfunction, and developmental delay. This article reports a boy manifested as delayed motor development, hypotonia, and oculogyric crisis. Gene screening for metabolic disorders revealed new compound heterozygous mutations, c.1063dupA (p.I355fs) and c.250A>C (p.S84R), in the exon of DDC gene...
January 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28099184/efficacy-of-vitamin-b6-in-lithium-associated-tremor-a-case-series
#18
Manuel Dias Alves, Laure Varin, Laura M Fiori, Bruno Etain, Jean-Michel Azorin, Raoul Belzeaux
No abstract text is available yet for this article.
January 18, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28098048/folate-and-vitamin-b12-concentrations-are-associated-with-plasma-dha-and-epa-fatty-acids-in-european-adolescents-the-healthy-lifestyle-in-europe-by-nutrition-in-adolescence-helena-study
#19
I Iglesia, I Huybrechts, M González-Gross, T Mouratidou, J Santabárbara, V Chajès, E M González-Gil, J Y Park, S Bel-Serrat, M Cuenca-García, M Castillo, M Kersting, K Widhalm, S De Henauw, M Sjöström, F Gottrand, D Molnár, Y Manios, A Kafatos, M Ferrari, P Stehle, A Marcos, F J Sánchez-Muniz, L A Moreno
This study aimed to examine the association between vitamin B6, folate and vitamin B12 biomarkers and plasma fatty acids in European adolescents. A subsample from the Healthy Lifestyle in Europe by Nutrition in Adolescence study with valid data on B-vitamins and fatty acid blood parameters, and all the other covariates used in the analyses such as BMI, Diet Quality Index, education of the mother and physical activity assessed by a questionnaire, was selected resulting in 674 cases (43 % males). B-vitamin biomarkers were measured by chromatography and immunoassay and fatty acids by enzymatic analyses...
January 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28095734/entrapment-efficiency-of-pyridoxine-hydrochloride-in-unilamellar-liposomes-experimental-versus-model-generated-data
#20
Heba Abd-El-Azim, Alyaa Ramadan, Noha Nafee, Nawal Khalafallah
The present study investigates the effect of the preparation method (four methods) and formulation additives (propylene glycol (PG) and cholesterol (CH)) on the entrapment efficiency (EE) of pyridoxine hydrochloride (vitamin B6 (VB6)), representing hydrophilic water-soluble low permeable vitamins, in unilamellar liposomes. The main aim is to compare determined EE with predicted values generated using a web-published, computational model. Results showed that among the different preparation methods, modified film hydration showed significantly higher EE (p < 0...
January 18, 2017: Journal of Liposome Research
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