Johannes Hilberath, Vittoria Camelli, Christiane Hofer, Steffen Hartleif, Silvio Nadalin, Maren Peters, Matthias Kumpf, Andrea Bevot, Matthias Zirngibl, Marcus Weitz, Ekkehard Sturm
OBJECTIVES: Paediatric acute liver failure (PALF) is a life-threatening disease. Management aims to support hepatic regeneration or to bridge to liver transplantation. High-volume plasmapheresis (HVP) removes protein-bound substances, alleviates inflammation, and improves survival in adult acute liver failure. However, experience with HVP in PALF is limited. Aim of this study is to report on feasibility, safety, efficacy and outcomes of HVP in PALF. METHODS: Retrospective observational study in children with PALF...
April 16, 2024: Journal of Pediatric Gastroenterology and Nutrition