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https://www.readbyqxmd.com/read/28230413/the-effects-of-cognitive-behavioral-therapy-are-not-systematically-falling-a-revision-of-johnsen-and-friborg-2015
#1
Ioana A Cristea, Simona Stefan, Eirini Karyotaki, Daniel David, Steven D Hollon, Pim Cuijpers
In a meta-analysis, Johnsen and Friborg (2015) reported a significant negative relationship between publication year and the effect sizes (ESs) of cognitive-behavioral therapy (CBT) for depressive disorders, suggesting its effectiveness was falling. We identified a series of methodological and conceptual caveats and consequently redid the meta-analysis. We used the same inclusion criteria, but only included randomized controlled trials and searched for additional eligible trials. We computed both within-group and between-group ESs for the CBT arm for the Beck Depression Inventory (BDI) and the Hamilton Rating Scale for Depression (HRSD)...
March 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28225509/psychometric-properties-of-the-reconstructed-hamilton-depression-and-anxiety-scales
#2
Eliora Porter, Dianne L Chambless, Kevin S McCarthy, Robert J DeRubeis, Brian A Sharpless, Marna S Barrett, Barbara Milrod, Steven D Hollon, Jacques P Barber
Although widely used, the Hamilton Rating Scale for Depression (HRSD) and Hamilton Anxiety Rating Scale (HARS) discriminate poorly between depression and anxiety. To address this problem, Riskind, Beck, Brown, and Steer (J Nerv Ment Dis. 175:474-479, 1987) created the Reconstructed Hamilton Scales by reconfiguring HRSD and HARS items into modified scales. To further analyze the reconstructed scales, we examined their factor structure and criterion-related validity in a sample of patients with major depressive disorder and no comorbid anxiety disorders (n = 215) or with panic disorder and no comorbid mood disorders (n = 149)...
February 20, 2017: Journal of Nervous and Mental Disease
https://www.readbyqxmd.com/read/28146251/effect-of-disorder-specific-vs-nonspecific-psychotherapy-for-chronic-depression-a-randomized-clinical-trial
#3
Elisabeth Schramm, Levente Kriston, Ingo Zobel, Josef Bailer, Katrin Wambach, Matthias Backenstrass, Jan Philipp Klein, Dieter Schoepf, Knut Schnell, Antje Gumz, Paul Bausch, Thomas Fangmeier, Ramona Meister, Mathias Berger, Martin Hautzinger, Martin Härter
Importance: Chronic depression is a highly prevalent and disabling disorder. There is a recognized need to assess the value of long-term disorder-specific psychotherapy. Objective: To evaluate the efficacy of the Cognitive Behavioral Analysis System of Psychotherapy (CBASP) compared with that of nonspecific supportive psychotherapy (SP). Design, Setting, and Participants: A prospective, multicenter, evaluator-blinded, randomized clinical trial was conducted among adult outpatients with early-onset chronic depression who were not taking antidepressant medication...
February 1, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28144920/the-impact-of-a-single-nucleotide-polymorphism-in-sigmar1-on-depressive-symptoms-in-major-depressive-disorder-and-bipolar-disorder
#4
Laura Mandelli, Sheng-Min Wang, Changsu Han, Soo-Jung Lee, Ashwin A Patkar, Prakash S Masand, Chi-Un Pae, Alessandro Serretti
INTRODUCTION: Ample evidence suggested a role of sigma-1 receptor in affective disorders since the interaction of numerous antidepressants with sigma receptors was discovered. A recent study on Japanese subjects found a genetic variant within the encoding gene SIGMAR1 (rs1800866A>C) associated with major depressive disorder (MDD). We aimed to evaluate the same polymorphism in both MDD and bipolar disorder (BD) as well as its relationship to response to treatment with antidepressants and mood stabilizers...
January 31, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28125252/change-in-self-reported-personality-during-major-depressive-disorder-treatment-a-reanalysis-of-treatment-studies-from-a-demoralization-perspective
#5
Arjen Noordhof, Jan H Kamphuis, Martin Sellbom, Annemarie Eigenhuis, R Michael Bagby
Change in self-reported personality trait scores (especially Neuroticism and Extraversion) over the course of treatment for major depressive disorder (MDD) has been robustly demonstrated. We believe that these observed changes on personality trait scales may reflect reduction in demoralization rather than changes in personality per se. Data were combined from 3 archival samples: a randomized clinical trial and 2 naturalistic follow-up studies. All participants (N = 300) received either psychotherapy or psychopharmacological treatment...
January 26, 2017: Personality Disorders
https://www.readbyqxmd.com/read/28009467/internet-based-cognitive-behavior-therapy-for-major-depressive-disorder-a-randomized-controlled-trial
#6
Isabelle M Rosso, William D S Killgore, Elizabeth A Olson, Christian A Webb, Rena Fukunaga, Randy P Auerbach, Hannah Gogel, Jennifer L Buchholz, Scott L Rauch
BACKGROUND: Prior research has shown that the Sadness Program, a technician-assisted Internet-based cognitive behavioral therapy (iCBT) intervention developed in Australia, is effective for treating major depressive disorder (MDD). The current study aimed to expand this work by adapting the protocol for an American population and testing the Sadness Program with an attention control group. METHODS: In this parallel-group, randomized controlled trial, adult MDD participants (18-45 years) were randomized to a 10-week period of iCBT (n = 37) or monitored attention control (MAC; n = 40)...
December 23, 2016: Depression and Anxiety
https://www.readbyqxmd.com/read/27965856/ketamine-for-depression-relapse-prevention-following-electroconvulsive-therapy-protocol-for-a-randomised-pilot-trial-the-keep-well-trial
#7
Martha Finnegan, Karen Ryan, Enda Shanahan, Andrew Harkin, Leslie Daly, Declan M McLoughlin
BACKGROUND: Major depressive disorder is a common debilitating illness that is the second leading contributor to the global burden of disease. Unfortunately, about 30 % of patients do not respond to adequate trials of antidepressants and/or psychotherapies. About 45-60 % of such treatment-resistant patients will remit with electroconvulsive therapy (ECT). However, relapse rates are high following ECT-38 % after 6 months. There is a need for better relapse prevention strategies. One possibility is to use ketamine, a competitive glutamate receptor antagonist used for anaesthesia...
2016: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/27833815/performance-usability-and-comparison-of-two-versions-of-a-new-macular-vision-test-the-handheld-radial-shape-discrimination-test
#8
Jae Y Ku, Ashli F Milling, Noelia Pitrelli Vazquez, Paul C Knox
BACKGROUND: Central vision, critical for everyday tasks such as reading and driving, is impacted by age-related changes in the eye and by diseases such as age-related macular degeneration. The detection of changes in macular function is therefore important. The Radial Shape Discrimination (RSD) test measures the threshold at which distortions in a radial frequency pattern can be detected and there is evidence that it is more sensitive to macular pathology than visual acuity (VA). It also provides a more quantitative measure of macular function than the commonly available Amsler grid...
2016: PeerJ
https://www.readbyqxmd.com/read/27810717/the-effectiveness-of-group-based-behavioral-activation-in-the-treatment-of-depression-an-updated-meta-analysis-of-randomized-controlled-trial
#9
Aaroy T Y Chan, Grace Y Y Sun, Wilson W S Tam, Kelvin K F Tsoi, Samuel Y S Wong
BACKGROUND: Depression is a common mental health problem associated with significant morbidity and mortality. Amongst various psychological treatments for depression, individual behavioral activation (BA) has been shown to be effective and relatively simple in its delivery by health care providers although its effectiveness as a group based intervention requires further evidence. The objective of this study is to evaluate and update on the effectiveness of group-based BA to relieve symptoms of depression...
January 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/27784414/are-patients-with-childhood-onset-of-insomnia-and-depression-more-difficult-to-treat-than-are-those-with-adult-onsets-of-these-disorders-a-report-from-the-triad-study
#10
Jack D Edinger, Rachel Manber, Daniel J Buysse, Andrew D Krystal, Michael E Thase, Phillip Gehrman, Christopher P Fairholme, James Luther, Stephen Wisniewski
STUDY OBJECTIVES: To determine if patients with childhood onsets (CO) of both major depression and insomnia disorder show blunted depression and insomnia treatment responses to concurrent interventions for both disorders compared to those with adult onsets (AO) of both conditions. METHODS: This study was a secondary analysis of data obtained from a multisite randomized clinical trial designed to test the efficacy of combining a psychological/behavior insomnia therapy with antidepressant medication to enhance depression treatment outcomes in patients with comorbid major depression and insomnia...
February 15, 2017: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27751859/abnormal-dynamics-of-cortical-resting-state-functional-connectivity-in-chronic-headache-patients
#11
Zewei Wang, Qing Yang, Li Min Chen
The goals of this study are to characterize the temporal dynamics of inter-regional connectivity of the brain in chronic headache (CH) patients versus their age/gender matched controls (CONCH, n=28 pairs), and to determine whether dynamic measures reveal additional features to static functional connectivity and correlate with psychometric scores. Cortical thickness and inter-regional resting state fMRI connectivity were quantified and compared between CH and CONCH groups. Six cortical regions of interest (ROI) pairs that exhibited correlated cortical thickness and static functional connectivity abnormalities were selected for temporal dynamic analysis...
October 14, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27551669/accuracy-of-automated-classification-of-major-depressive-disorder-as-a-function-of-symptom-severity
#12
Rajamannar Ramasubbu, Matthew R G Brown, Filmeno Cortese, Ismael Gaxiola, Bradley Goodyear, Andrew J Greenshaw, Serdar M Dursun, Russell Greiner
BACKGROUND: Growing evidence documents the potential of machine learning for developing brain based diagnostic methods for major depressive disorder (MDD). As symptom severity may influence brain activity, we investigated whether the severity of MDD affected the accuracies of machine learned MDD-vs-Control diagnostic classifiers. METHODS: Forty-five medication-free patients with DSM-IV defined MDD and 19 healthy controls participated in the study. Based on depression severity as determined by the Hamilton Rating Scale for Depression (HRSD), MDD patients were sorted into three groups: mild to moderate depression (HRSD 14-19), severe depression (HRSD 20-23), and very severe depression (HRSD ≥ 24)...
2016: NeuroImage: Clinical
https://www.readbyqxmd.com/read/27536110/clinical-characteristics-of-synthetic-cannabinoid-induced-psychosis-in-relation-to-schizophrenia-a-single-center-cross-sectional-analysis-of-concurrently-hospitalized-patients
#13
Merih Altintas, Leman Inanc, Gamze Akcay Oruc, Selim Arpacioglu, Huseyin Gulec
BACKGROUND: This study aimed to evaluate synthetic cannabinoid (SC)-induced psychosis in terms of patient profile and clinical characteristics with reference to concurrently hospitalized schizophrenic patients. METHODS: A total of 81 male patients diagnosed with psychotic disorder induced by the use of SCs (n=50; mean (standard deviation [SD]) age: 25.9 (5.5) years) or with schizophrenia (n=31, mean (SD) age: 42.9 (11.6) years) based on the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, diagnosis criteria who were concurrently hospitalized at Erenköy Mental and Neurological Diseases Training and Research Hospital were included in this cross-sectional study...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27450310/validation-of-the-polish-version-of-the-hamilton-rating-scale-for-depression-in-patients-with-epilepsy
#14
Mariusz S Wiglusz, Jerzy Landowski, Lidia Michalak, Wiesław J Cubała
OBJECTIVE: Depressive disorders are the most common comorbidities among patients with epilepsy (PWE). The availability of standardized clinical instruments for PWE is limited with scarce validation studies available so far. The aim of the study was to validate the Polish Version of the Hamilton Rating Scale for Depression (HRSD) in adult PWE. METHODS: A group of 96 outpatient PWE were examined by a trained psychiatrist using the Structured Clinical Interview (SCID-I) for DSM-IV-TR and the 17-item Polish Version of HRSD (HRSD-17)...
September 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27417581/dietary-saturated-fatty-acids-and-coronary-heart-disease-risk-in-a-dutch-middle-aged-and-elderly-population
#15
Jaike Praagman, Ester A L de Jonge, Jessica C Kiefte-de Jong, Joline W J Beulens, Ivonne Sluijs, Josje D Schoufour, Albert Hofman, Yvonne T van der Schouw, Oscar H Franco
OBJECTIVE: We assessed whether the association between dietary saturated fatty acids (SFA) and incident coronary heart disease (CHD) depends on the food source, the carbon chain length of SFA, and the substituting macronutrient. APPROACH AND RESULTS: From the Rotterdam Study, 4722 men and women (≥55 years) were included. Baseline (1990-1993) SFA intake was assessed using a validated food frequency questionnaire. CHD (nonfatal myocardial infarction and fatal CHD) was ascertained by medical records...
September 2016: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/27263299/-expression-of-serotonin-receptor-and-transporter-related-genes-of-cd4-t-lymphocytes-in-patients-with-asthma-and-depression
#16
Ren-zhi Chen, Min Zhu, Wang Ting, Yu-lin Ji
OBJECTIVE: To explore the comorbidity mechanism of asthma and depression. METHODS: A self-developed questionnaire, which also contained Asthma Control Test (ACT), Asthma Quality of Life Questionnaire (AQLQ) and Hamilton Rating Scale for depression ( HRSD), was administered in 41 participants with asthma (AS), asthma and depression (AD), or none any of these conditions (health control, HC). Lung function and blood levels of eosnophils and IgE were also detected in those in the AS and AD groups...
March 2016: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/27195784/differences-in-quality-of-life-of-women-and-men-with-drug-resistant-epilepsy-in-poland
#17
Aleksandra Bala, Marta Szantroch, Alicja Gleinert, Andrzej Rysz, Andrzej Marchel
PURPOSE: The aim of the study was to assess the differences in health-related quality of life in groups of men and women suffering with drug-resistant epilepsy and to determine which factors influence quality of life. METHODS: The examined group consisted of 64 subjects with drug-resistant epilepsy - 31 men and 33 women. The mean duration of epilepsy was 17.56±8.92 and 19±9.56years, respectively. The following diagnostic tools were used: QOLIE-31-P, Wechsler Adult Intelligence Scale - Revised (WAIS-R (PL)), and Hamilton Rating Scale for Depression (HRSD)...
July 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/27156024/evaluations-of-treatment-efficacy-of-depression-from-perspective-of-both-patients-symptoms-and-general-sense-of-mental-health-and-wellbeing-a-large-scale-multi-centered-longitudinal-study-in-china
#18
Qingzhi Zeng, Wei Chun Wang, Yiru Fang, David Mellor, Marita Mccabe, Linda Byrne, Sai Zuo, Yifeng Xu
Relying on the absence, presence of level of symptomatology may not provide an adequate indication of the effects of treatment for depression, nor sufficient information for the development of treatment plans that meet patients' needs. Using a prospective, multi-centered, and observational design, the present study surveyed a large sample of outpatients with depression in China (n=9855). The 17-item Hamilton Rating Scale for Depression (HRSD-17) and the Remission Evaluation and Mood Inventory Tool (REMIT) were administered at baseline, two weeks later and 4 weeks, to assess patients' self-reported symptoms and general sense of mental health and wellbeing...
July 30, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27124715/additive-genetic-contribution-to-symptom-dimensions-in-major-depressive-disorder
#19
Rahel Pearson, Rohan H C Palmer, Leslie A Brick, John E McGeary, Valerie S Knopik, Christopher G Beevers
Major depressive disorder (MDD) is a phenotypically heterogeneous disorder with a complex genetic architecture. In this study, genomic-relatedness-matrix restricted maximum-likelihood analysis (GREML) was used to investigate the extent to which variance in depression symptoms/symptom dimensions can be explained by variation in common single nucleotide polymorphisms (SNPs) in a sample of individuals with MDD (N = 1,558) who participated in the National Institute of Mental Health Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study...
2016: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/27099642/repetitive-transcranial-magnetic-stimulation-for-treatment-resistant-depression-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#20
REVIEW
(no author information available yet)
BACKGROUND: To date, several randomized controlled trials (RCTs) have shown the efficacy of repetitive transcranial magnetic stimulation (rTMS) in the treatment of major depression. OBJECTIVE: This analysis examined the antidepressant efficacy of rTMS in patients with treatment-resistant unipolar depression. METHODS: A literature search was performed for RCTs published from January 1, 1994, to November 20, 2014. The search was updated on March 1, 2015...
2016: Ontario Health Technology Assessment Series
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