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https://www.readbyqxmd.com/read/28723746/effects-of-hyperbaric-oxygen-therapy-on-depression-and-anxiety-in-the-patients-with-incomplete-spinal-cord-injury-a-strobe-compliant-article
#1
Juan-Juan Feng, You-Hui Li
Little research has been done on the effects of hyperbaric oxygen (HBO) on depression and anxiety after spinal cord injury (SCI). The aim of this study was to investigate the effects of HBO on psychological problems and never function, especially on depression and anxiety in the patients with incomplete SCI (ISCI).Sixty patients with ISCI combined with depression and anxiety were randomly divided into HBO group (20 cases), psychotherapy group (20 cases), and conventional rehabilitation control group (20 cases)...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28721053/reduced-prefrontal-activation-during-verbal-fluency-task-in-chronic-insomnia-disorder-a-multichannel-near-infrared-spectroscopy-study
#2
Jing-Jing Sun, Xiao-Min Liu, Chen-Yu Shen, Xiao-Qian Zhang, Gao-Xiang Sun, Kun Feng, Bo Xu, Xia-Jin Ren, Xiang-Yun Ma, Po-Zi Liu
PURPOSE: Daytime complaints such as memory and attention deficits and failure to accomplish daily tasks are common in insomnia patients. However, objective psychological tests to detect cognitive impairment are equivocal. Neural function associated with cognitive performance may explain the discrepancy. The aim of this study was to investigate the hemodynamic response patterns of patients with chronic insomnia disorder (CID) using the noninvasive and low-cost functional neuroimaging technique of multichannel near-infrared spectroscopy (NIRS) in order to identify changes of neural function associated with cognitive performance...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28718346/effect-of-desvenlafaxine-50-mg-and-100-mg-on-energy-and-lassitude-in-patients-with-major-depressive-disorder-a-pooled-analysis
#3
Raymond W Lam, Dalia B Wajsbrot, Ellen Meier, Elizabeth Pappadopulos, Joan A Mackell, Matthieu Boucher
Nine randomized, double-blind, placebo-controlled studies of major depressive disorder were pooled to evaluate the effects of desvenlafaxine 50- and 100-mg/d on energy and lassitude in adults with major depressive disorder ( n=4279). Changes from baseline to endpoint in 17-item Hamilton Rating Scale for Depression (HAM-D17) Work and Activities, Retardation, and Somatic Symptoms General items, HAM-D17 psychomotor retardation factor, and Montgomery-Åsberg Depression Rating Scale Lassitude item were analyzed with a mixed model for repeated measures analysis of variance...
July 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28718244/depression-in-type-2-diabetic-patients-presenting-to-a-tertiary-care-hospital-in-pakistan
#4
Ahmed Farhan, Amir Raza Ayub, Jamal Zafar
BACKGROUND: Diabetes affects almost every system including mental health. When depression and diabetes coexist, the outcome is even worse. This study was conducted to find the prevalence of comorbid depression in diabetic patients and its association with diabetic control. METHODS: This was a descriptive cross sectional observational study conducted in the department of general medicine of Pakistan Institute of Medical Sciences, Islamabad from March to September 2014...
April 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28713690/three-dimensional-stereotactic-surface-projection-in-the-statistical-analysis-of-single-photon-emission-computed-tomography-data-for-distinguishing-between-alzheimer-s-disease-and-depression
#5
Eiji Kirino
AIM: To evaluate usefulness of single photon emission computed tomography (SPECT) with three-dimensional stereotactic surface projection (3D-SSP) in distinguishing between Alzheimer's disease (AD) and depression. METHODS: We studied 43 patients who presented with both depressive symptoms and memory disturbance. Each subject was evaluated using the following: (1) the Minimal Mental State Examination; (2) the Hamilton Rating Scale for Depression; (3) Clinical Global Impression-Severity scale (CGI-S); and (4) SPECT imaging with 3D-SSP...
June 22, 2017: World Journal of Psychiatry
https://www.readbyqxmd.com/read/28709880/low-intensity-transcranial-electric-stimulation-safety-ethical-legal-regulatory-and-application-guidelines
#6
REVIEW
A Antal, I Alekseichuk, M Bikson, J Brockmöller, A R Brunoni, R Chen, L G Cohen, G Dowthwaite, J Ellrich, A Flöel, F Fregni, M S George, R Hamilton, J Haueisen, C S Herrmann, F C Hummel, J P Lefaucheur, D Liebetanz, C K Loo, C D McCaig, C Miniussi, P C Miranda, V Moliadze, M A Nitsche, R Nowak, F Padberg, A Pascual-Leone, W Poppendieck, A Priori, S Rossi, P M Rossini, J Rothwell, M A Rueger, G Ruffini, K Schellhorn, H R Siebner, Y Ugawa, A Wexler, U Ziemann, M Hallett, W Paulus
Low intensity transcranial electrical stimulation (TES) in humans, encompassing transcranial direct current (tDCS), transcutaneous spinal Direct Current Stimulation (tsDCS), transcranial alternating current (tACS), and transcranial random noise (tRNS) stimulation or their combinations, appears to be safe. No serious adverse events (SAEs) have been reported so far in over 18,000 sessions administered to healthy subjects, neurological and psychiatric patients, as summarized here. Moderate adverse events (AEs), as defined by the necessity to intervene, are rare, and include skin burns with tDCS due to suboptimal electrode-skin contact...
June 19, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28708736/mifepristone-plasma-level-and-glucocorticoid-receptor-antagonism-associated-with-response-in-patients-with-psychotic-depression
#7
Thaddeus Block, Georgios Petrides, Harvey Kushner, Ned Kalin, Joseph Belanoff, Alan Schatzberg
BACKGROUND: Psychotic depression has no Food and Drug Administration-approved treatment. Patients demonstrate significant dysregulation of the hypothalamic-pituitary-adrenal axis providing a biologically targeted treatment opportunity. The purpose of this study was to explore the clinical and biological effects of short-duration (7-day) glucocorticoid receptor antagonism with mifepristone and the role of mifepristone plasma levels in patients with psychotic depression. METHODS: This double-blind, randomized study took place at 34 US clinical research centers and included patients with a diagnosis of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, major depressive disorder, severe, with psychotic features...
July 13, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/28703949/psychotherapy-alone-and-combined-with-medication-as-treatments-for-bipolar-ii-depression-a-randomized-controlled-trial
#8
Holly A Swartz, Paola Rucci, Michael E Thase, Meredith Wallace, Elisa Carretta, Karen L Celedonia, Ellen Frank
OBJECTIVE: Bipolar II disorder (BP-II) is associated with marked morbidity and mortality. Quetiapine, the treatment with greatest evidence for efficacy in BP-II depression, is associated with metabolic burden. Psychotherapy, a treatment with few side effects, has not been systematically evaluated in BP-II. This study compared psychotherapy plus placebo to psychotherapy plus pharmacotherapy as treatments for BP-II depression. METHODS: From 2010 to 2015, unmedicated adults (n = 92) with DSM-IV-TR BP-II depression were randomly assigned to weekly sessions of Interpersonal and Social Rhythm Therapy (IPSRT) plus placebo or IPSRT plus quetiapine and followed for 20 weeks...
July 11, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28700039/sexual-dysfunction-in-females-with-depression-a-cross-sectional-study
#9
Krishnankutty Sreelakshmy, Rajmohan Velayudhan, Deepak Kuriakose, Rema Nair
Introduction: Female sexual dysfunction (FSD) in depression albeit common is strikingly understudied. The condition, if addressed properly, can be readily cured, improving the quality of life of the patient. Methods: A consecutive sample of drug-naïve married female patients with depression was assessed. Depression was diagnosed using the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I). Depression severity was assessed using the Hamilton Depression Rating Scale (HAM-D), and sexual dysfunction, the Female Sexual Function Index (FSFI)...
April 2017: Trends in Psychiatry and Psychotherapy
https://www.readbyqxmd.com/read/28699630/prevalence-and-clinical-correlation-of-dysphagia-in-parkinson-disease-a-study-on-chinese-patients
#10
X Ding, J Gao, C Xie, B Xiong, S Wu, Z Cen, Y Lou, D Lou, F Xie, W Luo
BACKGROUND/OBJECTIVES: Dysphagia is relatively common in patients with Parkinson disease (PD) and can have a negative impact on their quality of life; therefore, it is imperative that its prevalence in PD patients is studied. The aim of this study was to explore the prevalence and clinical correlation of dysphagia in Chinese PD patients. SUBJECTS/METHODS: We recruited 116 Chinese PD patients. A videofluoroscopic study of swallowing (VFSS) was used to identify dysphagia...
July 12, 2017: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28698150/freezing-of-gait-is-associated-with-cognitive-impairment-in-patients-with-parkinson-disease
#11
Zhiwen Yao, Yuan Shao, Xiang Han
OBJECTIVE: To explore whether the cognitive impairment is correlated with freezing of gait (FOG) in patients with Parkinson disease (PD). METHODS: A total of 186 patients with Parkinson disease (104 patients with FOG and 82 patients with no clinical history of freezing behavior) and 125 healthy individuals were selected for this study. Neuropsychological assessments, including the scales for outcomes in Parkinson disease cognition, unified Parkinson's disease rating scale, and Hamilton depression/anxiety rating scale etc...
July 8, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28694708/spiritual-care-may-impact-mental-health-and-medication-adherence-in-hiv-populations
#12
Valerie U Oji, Leslie C Hung, Reza Abbasgholizadeh, Flora Terrell Hamilton, E James Essien, Evaristus Nwulia
OBJECTIVE: To explore a potential role for spirituality in medication-related needs assessment for integrated care in chronically ill populations. METHOD: A systematic literature review was conducted to explore the impact of faith beliefs on health and/or medication adherence in individuals with depression and/or HIV+/AIDS. Retrospective electronic medical record review of adult HIV+ patients of an urban primary care clinic with integrated mental health services was conducted, with Substance Abuse and Mental Illness Symptoms Screener (SAMISS), major depressive disorder (MDD) incidence over the preceding year, and history of contact with a spiritual advisor...
2017: HIV/AIDS: Research and Palliative Care
https://www.readbyqxmd.com/read/28694701/high-levels-of-nesfatin-1-in-relation-to-the-dysfunction-of-the-hypothalamic-pituitary-adrenal-and-hypothalamus-pituitary-thyroid-axes-in-depressed-patients-with-subclinical-hypothyroidism
#13
Ya-Yun Xu, Jun Liang, Yin Cao, Feng Shan, Yang Liu, Qing-Rong Xia
Despite the increasing amount of evidence suggesting a relationship between depression and subclinical hypothyroidism (SCH), the exact mechanism underlying this relationship remains unclear. The main purpose of this study was to investigate the roles of plasma Nesfatin-1 levels and dysfunction of the hypothalamic-pituitary-adrenal (HPA) and hypothalamus-pituitary-thyroid (HPT) axes in the comorbidity of depression and SCH. Dysfunctions of the HPA and HPT axes were detected by measuring plasma corticosterone and thyroid-stimulating hormone (TSH) concentrations, respectively...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28694611/depression-as-a-manifestation-of-obstructive-sleep-apnea
#14
Sheikh Shoib, Javid A Malik, Shariq Masoodi
BACKGROUND: Obstructive sleep apnea (OSA) often results in a wide range of comorbid conditions, predominantly of the cardiovascular/respiratory, endocrine/metabolic, and neuropsychiatric symptoms. In view of the ambiguity of literature regarding the association between OSA and depression, we conducted this study to show any association between the two disorders. OBJECTIVE: The aim of the study was to see the association between OSA and depression and to study the prevalence of OSA in patients suffering from depression...
July 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28693073/-resting-state-fmri-study-of-emotional-network-in-patients-with-postconcussion-syndrome
#15
X Zhang, R B Qian, X M Fu, B Lin, D Zhang, C S Xia, X P Wei, C S Niu, Y H Wang
Objective: To discuss functional connectivity changes in the emotional network of patients with post-concussion syndrome (PCS) and their clinical significance by resting-state functional magnetic resonance imaging (rs-fMRI). Methods: Twenty-seven patients with PCS were recruited from the Department of Neurosurgery of Anhui provincial hospital affiliated to Anhui medical university from October 2015 to April 2016, and 27 healthy subjects were recruited as the controls. The Hamilton Anxiety Scale (HAMA) and The Hamilton Depression Scale (HAMD) were used to evaluate the emotional state of two groups of subjects...
July 4, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28692905/prediction-of-outcome-of-bright-light-treatment-in-patients-with-seasonal-affective-disorder-discarding-the-early-response-confirming-a-higher-atypical-balance-and-uncovering-a-higher-body-mass-index-at-baseline-as-predictors-of-endpoint-outcome
#16
Tzvetelina D Dimitrova, Gloria M Reeves, Soren Snitker, Manana Lapidus, Aamar R Sleemi, Theodora G Balis, Partam Manalai, Muhammad M Tariq, Johanna A Cabassa, Naila N Karim, Mary A Johnson, Patricia Langenberg, Kelly J Rohan, Michael Miller, John W Stiller, Teodor T Postolache
BACKGROUND: We tested the hypothesis that the early improvement in mood after the first hour of bright light treatment compared to control dim-red light would predict the outcome at six weeks of bright light treatment for depressed mood in patients with Seasonal Affective Disorder (SAD). We also analyzed the value of Body Mass Index (BMI) and atypical symptoms of depression at baseline in predicting treatment outcome. METHODS: Seventy-eight adult participants were enrolled...
June 22, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28690204/depressive-anxiety-and-hypomanic-symptoms-in-schizophrenia-may-be-driven-by-tryptophan-catabolite-trycat-patterning-of-iga-and-igm-responses-directed-to-trycats
#17
Buranee Kanchanatawan, Sunee Sirivichayakul, André F Carvalho, George Anderson, Piotr Galecki, Michael Maes
The aim of this study was to delineate the associations between the tryptophan catabolite (TRYCAT) pathway and affective symptoms in schizophrenia. Towards this end we measured immunoglobulin (Ig)A and IgM responses to relatively noxious TRYCATs, namely quinolinic (QA), xanthurenic (XA), picolinic (PA) acid and 3-OH-kynurenine (3HK), and generally protective TRYCATs, namely anthranilic (AA) and kynurenic (KA) acid in 80 patients with schizophrenia and 40 healthy controls. The Hamilton Rating Scale for Depression (HDRS) and anxiety (HAMA), Young Mania Rating Scale (YMRS) as well as the Positive and Negative Symptoms Scale of Schizophrenia (PANSS) were measured...
July 6, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28689143/glial-cell-line-derived-neurotrophic-factor-gdnf-serum-level-in-women-with-schizophrenia-and-depression-correlation-with-clinical-and-metabolic-parameters
#18
Maria Skibinska, Pawel Kapelski, Joanna Pawlak, Aleksandra Rajewska-Rager, Monika Dmitrzak-Weglarz, Aleksandra Szczepankiewicz, Piotr Czerski, Joanna Twarowska-Hauser
AIM: Neurotrophic factors have been implicated in neuropsychiatric disorders, including schizophrenia and depression. Glial Cell Line-Derived Neurotrophic Factor (GDNF) promotes development, differentiation, and protection of dopaminergic, serotonergic, GABAergic and noradrenergic neurons as well as glial cells in different brain regions. This study examined serum levels of GDNF in schizophrenia and depression and its correlation with metabolic parameters during 8 weeks of treatment. METHODS: Serum GDNF level, fasting serum glucose and lipid profile were measured at baseline and week 8 in 133 women: 55 with schizophrenia, 30 with a first episode depression and 48 healthy controls...
July 6, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28686904/gender-differences-in-susceptibility-to-schizophrenia-potential-implication-of-neurosteroids
#19
Yu-Chi Huang, Chi-Fa Hung, Pao-Yen Lin, Yu Lee, Chih-Ching Wu, Su-Ting Hsu, Chien-Chih Chen, Mian-Yoon Chong, Chieh-Hsin Lin, Liang-Jen Wang
Past research has indicated gender differences in the clinical characteristics and course of schizophrenia. In this study, we investigated whether gender differences in the manifestation of schizophrenia are correlated with neurosteroids, including dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and pregnenolone. We further explored the potential relationship between the aforementioned neurosteroids and psychopathology. We recruited 65 schizophrenic patients (36 males and 29 females) and 103 healthy control subjects (47 males and 56 females) and obtained blood samples from the subjects in the morning while in a fasting state to determine the serum levels of DHEA, DHEA-S, and pregnenolone...
June 26, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28684258/effects-of-transcranial-direct-current-stimulation-on-pain-mood-and-serum-endorphin-level-in-the-treatment-of-fibromyalgia-a-double-blinded-randomized-clinical-trial
#20
Eman M Khedr, Eman A H Omran, Nadia M Ismail, Dina H El-Hammady, Samar H Goma, Hassan Kotb, Hannan Galal, Ayman M Osman, Hannan S M Farghaly, Ahmed A Karim, Gehad A Ahmed
BACKGROUND: Recent studies have shown that novel neuro-modulating techniques can have pain-relieving effects in the treatment of chronic pain. The aim of this work is to evaluate the effects of transcranial direct current stimulation (tDCS) in relieving fibromyalgia pain and its relation with beta-endorphin changes. MATERIAL AND METHODS: Forty eligible patients with primary fibromyalgia were randomized to receive real anodal tDCS or sham tDCS of the left motor cortex (M1) daily for 10 days...
June 23, 2017: Brain Stimulation
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