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https://www.readbyqxmd.com/read/29344938/a-clinical-audit-on-the-efficacy-and-safety-of-uterine-artery-embolisation-for-symptomatic-adenomyosis-results-in-117-women
#1
Eisen Liang, Bevan Brown, Maxim Rachinsky
BACKGROUND: Uterine artery embolisation (UAE) is a possible uterine-sparing treatment option for women with unsuccessful conservative management for adenomyosis-related heavy menstrual bleeding (HMB) and dysmenorrhoea. AIM: To conduct a clinical audit on the efficacy and safety of UAE for symptomatic adenomyosis. MATERIALS AND METHODS: Retrospective review of 309 women who underwent UAE identified 117 women with magnetic resonance imaging features of adenomyosis (junctional zone thickness ≥ 12 mm)...
January 18, 2018: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/29334974/prevalence-of-dysmenorrhea-and-predictors-of-its-pain-intensity-among-palestinian-female-university-students
#2
Heba A Abu Helwa, Areen A Mitaeb, Suha Al-Hamshri, Waleed M Sweileh
BACKGROUND: Few studies on gynaecological problems of young females in Arab countries were published. The aim of this study was to determine the prevalence of dysmenorrhea and predictors of its pain among university students in Palestine. METHODS: A cross - sectional study was carried out on a randomly selected sample of An-Najah National University female students. A pre-designed questionnaire, which included questions regarding menstrual cycle, pain during menstruation, life style, nutritional habits, and symptoms associated with menstrual pain, was used...
January 15, 2018: BMC Women's Health
https://www.readbyqxmd.com/read/29332111/prevalence-of-menstrual-problems-and-their-association-with-psychological-stress-in-young-female-students-studying-health-sciences
#3
Nazish Rafique, Mona H Al-Sheikh
To identify the prevalence of various menstrual problems in young females studying health sciences and to identify their association with academic stress. Methods: This was a cross-sectional study, conducted in the health colleges of Immam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia between February 2015 and February 2016. Seven hundred and thirty-eight female students aged 18-25 years anonymously completed menstrual problem identification and perceived stress scale questionnaire. The data was analyzed using the Statistical Package for Social Sciences version 16...
January 2018: Saudi Medical Journal
https://www.readbyqxmd.com/read/29330150/dysfunctional-signaling-underlying-endometriosis-current-state-of-knowledge
#4
Yeon Jean Cho, Seung Hyun Lee, Jung Woo Park, Myoungseok Han, Mi Jin Park, Sang Jun Han
Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity. It affects approximately 5-10% of women of reproductive age. Endometriosis is associated with dysmenorrhea, dyspareunia and, often, severe pelvic pain. In addition to pain, women with endometriosis often experience infertility. Defining the molecular etiology of endometriosis is a significant challenge for improving the quality of women's lives. Unfortunately, the pathophysiology of endometriosis is not well understood...
January 12, 2018: Journal of Molecular Endocrinology
https://www.readbyqxmd.com/read/29321498/the-ppi-network-analysis-of-mrna-expression-profile-of-uterus-from-primary-dysmenorrheal-rats
#5
Pei Fan, Qiao-Hui Lin, Ying Guo, Lan-Ling Zhao, He Ning, Meng-Ying Liu, Dong-Qing Wei
To elucidate the mechanisms of molecular regulations underlying primary dysmenorrhea (PD), we used our previously published mRNA expression profile of uterus from PD syndrome rats to construct protein-protein interactions (PPI) network via STRING Interactome. Consequently, 34 subnetworks, including a "continent" (Subnetwork 1) and 33 "islands" (Subnetwork 2-34) were generated. The nodes, with relative expression ratios, were visualized in the PPI networks and their connections were identified. Through path and module exploring in the network, the bridges were found from pathways of cellular response to calcium ion, SMAD protein signal transduction, regulation of transcription from RNA polymerase II promoter in response to stress and muscle stretch that were significantly enriched by the up-regulated mRNAs, to the cascades of cAMP metabolic processes and positive regulation of cyclase activities by the down-regulated ones...
January 10, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29320956/transvaginal-elastosonography-as-an-imaging-technique-for-diagnosing-adenomyosis
#6
Xishi Liu, Ding Ding, Yunyun Ren, Sun-Wei Guo
To test the hypothesis that the lesional stiffness as measured by transvaginal elastosonography (TVESG) correlates with the extent of fibrosis in adenomyotic (AM) lesions, and thus TVESG can be used to diagnose AM, we conducted 2 studies. The first evaluated the relationship, if any, between lesional stiffness and lesional histology in 35 women with histologically confirmed AM in comparison with tissue stiffness in 11 control myometrial (CM) and 8 uterine fibroids (UFs) tissue samples. The second validated the relationship between lesional stiffness and the severity of dysmenorrhea and the amount of menses in AM patients by recruiting 112 patients diagnosed with AM, 67 with UF, and 130 controls...
January 1, 2018: Reproductive Sciences
https://www.readbyqxmd.com/read/29320327/atypical-sites-of-deeply-infiltrative-endometriosis-clinical-characteristics-and-imaging-findings
#7
Luciana P Chamié, Duarte Miguel Ferreira Rodrigues Ribeiro, Dario A Tiferes, Augusto Cesar de Macedo Neto, Paulo C Serafini
Endometriosis is defined as the presence of endometrial tissue that is located outside the uterine cavity and associated with fibrosis and inflammatory reaction. It is a polymorphic and multifocal disease with no known cure or preventive mechanisms. Patients may be asymptomatic or may experience chronic pelvic pain, dysmenorrhea, dyspareunia, or infertility. The pelvic cavity is the most common location for endometriotic implants, which usually affect the retrocervical space, ovaries, vagina, rectosigmoid colon, bladder dome, and round ligaments...
January 2018: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/29317960/different-effects-of-oral-contraceptive-and-dydrogesterone-treatment-on-oxidative-stress-levels-in-premenopausal-women
#8
Jui-Tung Chen, Kazuhiko Kotani
Background: The aim of the study was to observe the changes in blood oxidative stress levels by oral contraceptive (OC) and/or dydrogesterone (DG) treatment. Methods: A retrospective cohort of 27 premenopausal women with primary dysmenorrhea consisted of the OC treatment group (N = 17) and the DG treatment group (N = 10) by choice of the initial treatment. The OC group included two subgroups: patients with continuous OC treatment (treated for at least 15 months, N = 10) and patients with discontinuous OC treatment (switched to DG treatment after approximately 6 months of initial OC treatment: N = 7)...
February 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29310371/treatment-of-cornual-pregnancy-in-a-patient-with-adenomyosis-by-high-intensity-focused-ultrasound-hifu-ablation-a-case-report
#9
Lixia Yu, Linying Xu, Xiaoyan Xu
RATIONALE: Cornual ectopic pregnancy in adenomyosis patients is a rare clinical condition, which may require careful approach for accurate diagnosis and treatment. PATIENT CONCERNS: A 38-year-old woman presented with amenorrhea for 8 weeks and serum HCG levels of 1455 mmol/L. The B ultrasound showed an endometrial thickness of 1.7 cm, and the presence of a cystic structure (16 6 mm) at the right uterine horn. Color Doppler flow imaging (CDFI) accurately detected and confirmed the position of the cystic structure with its clear boundaries...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29302548/a-descriptive-cross-sectional-study-on-menstrual-hygiene-and-perceived-reproductive-morbidity-among-adolescent-girls-in-a-union-territory-india
#10
Prakash Mathiyalagen, Birundhanjali Peramasamy, Kavita Vasudevan, Mausumi Basu, Johnson Cherian, Buvaneshwari Sundar
Introduction: Menstruation is a milestone event in a girl's life and the beginning of reproductive life. Lack of knowledge and poor sanitary practices during menstruation has been associated with serious ill-health ranging from genital tract infections, urinary tract infections, and bad odor. Aim: This study aims to explore the knowledge, attitude, and practices about menstrual hygiene and perceived reproductive morbidity among adolescent school girls in Puducherry...
April 2017: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/29301557/development-and-content-validation-of-a-patient-reported-endometriosis-pain-daily-diary
#11
Floortje E van Nooten, Jennifer Cline, Celeste A Elash, Jean Paty, Matthew Reaney
BACKGROUND: Endometriosis is a common gynecological disorder that causes inflammation and pelvic pain. Endometriosis-related pain is best captured with patient-reported outcome (PRO) measures, however, assessment of endometriosis-related pain in clinical trials has been difficult in the absence of a reliable and valid PRO instrument. We describe the development of the Endometriosis Pain Daily Diary (EPDD), an electronic PRO developed as a survey instrument to assess endometriosis-related pain and its impact on patients' lives...
January 4, 2018: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29299770/a-role-for-the-endometrial-microbiome-in-dysfunctional-menstrual-bleeding
#12
Elise S Pelzer, Dana Willner, Melissa Buttini, Flavia Huygens
This study aimed to characterise the microbial community within the endometrial cavity and endocervix in women with menorrhagia or dysmenorrhea. Paired endocervical and endometrial biopsy samples were collected from women undergoing operative hysteroscopy and/or laparoscopy. Samples were cohorted based on pathology, indications for surgery, and histological dating of the endometrium. Samples were interrogated for the presence of microbial DNA using a two-step next generation sequencing technology approach to exploit the V5-V8 regions of the 16S rRNA gene...
January 3, 2018: Antonie Van Leeuwenhoek
https://www.readbyqxmd.com/read/29299139/reduced-alternative-splicing-of-estrogen-receptor-alpha-in-the-endometrium-of-women-with-endometriosis
#13
Ying Zhang, Yong Zhang, Chunbo Zhao, Tiantian Yu, Ye Liu, Weihui Shi, Fengtao Shi, Xinmei Liu, Jianzhong Sheng, Hefeng Huang, Hong Xu
Endometriosis is a condition which involves the presence of uterine stroma and glands outside of the uterine cavity and represents one of the most prevalent disorders of the female reproductive tract. The key symptom of endometriosis is pain, including dysmenorrhea, deep dyspareunia, and chronic pelvic pain. As such, endometriosis has significant economic consequences within the healthcare system and can influence the daily quality of life in affected patients. However, the pathophysiology of this disease and the mechanisms in which this condition generates pain are very unclear...
December 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/29298793/spontaneous-rupture-of-uterine-smooth-muscle-tumour-presenting-acute-abdominal-pain-and-haemoperitoneum
#14
Hanako Oda, Hiroshi Hirakawa
Uterine smooth muscle tumours are histologically categorised into benign leiomyoma, malignant leiomyosarcoma or smooth muscle tumours of uncertain malignant potentials (STUMPs).1 Common symptoms of uterine tumours are hypermenorrhea, dysmenorrhea, lumbago or irregular genital bleeding. We experienced a case of uterine tumour with atypical clinical behaviour. A 40-year-old woman who had been diagnosed with leiomyoma presented with severe abdominal pain and intraperitoneal haemorrhage. By emergent surgery, we found that the uterine tumour had ruptured spontaneously...
January 3, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29298525/bleeding-pattern-difference-between-levonorgestrel-intrauterine-system-and-copper-intrauterine-devices-inserted-immediately-post-abortion-a-multicenter-prospective-observational-cohort-study-in-chinese-women
#15
Xiaoning Chen, Qianxi Li, Xiaoye Wang, Jing Chen, Wen Lv, Bin Shi, Hong Wang, Jianru Luo, Jian Li
BACKGROUND: To describe the bleeding pattern (primary outcome), side effects, treatment satisfaction, and 6-month continuity rates of 52 mg levonorgestrel-intrauterine system (LNG-IUS) and copper intrauterine device (Cu-IUD) inserted immediately after abortion. METHODS: This multicenter, prospective, observational cohort study enrolled healthy women (aged ≥18 years) inserted with LNG-IUS or Cu-IUD immediately after first-trimester surgical abortion and were followed up to 6 months...
January 3, 2018: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29282583/high-quality-human-preimplantation-embryos-actively-influence-endometrial-stromal-cell-migration
#16
R P Berkhout, C B Lambalk, J Huirne, V Mijatovic, S Repping, G Hamer, S Mastenbroek
PURPOSE: The purpose of this paper is to study whether human preimplantation embryos regulate endometrial stromal cell (hESC) migration. METHODS: Primary hESCs were isolated from fertile patients undergoing hysterectomy for benign conditions (uterine scar niche n = 3, dysmenorrhea n = 2; no hormonal treatment). Migration and proliferation assays were performed by culturing decidualized or non-decidualized hESCs in the presence of embryo conditioned medium (ECM) from high-quality embryos (fragmentation ≤ 20%) or from low-quality embryos (fragmentation > 20%) or in non-conditioned medium from the same dishes (control)...
December 28, 2017: Journal of Assisted Reproduction and Genetics
https://www.readbyqxmd.com/read/29234428/network-pharmacology-based-approach-to-investigate-the-analgesic-efficacy-and-molecular-targets-of-xuangui-dropping-pill-for-treating-primary-dysmenorrhea
#17
Jihan Huang, Lei Li, Fan Cheung, Ning Wang, Yunfei Li, Zhenyu Fan, Fang Yin, Juan Yang, Rui Gao, Yingchun He, Yibin Feng
This study aimed to evaluate the clinical analgesic efficacy and identify the molecular targets of XGDP for treating primary dysmenorrhea (PD) by a network pharmacology approach. Analysis of pain disappearance rate of XGDP in PD treatment was conducted based on data from phase II and III randomized, double-blind, double-simulation, and positive parallel controlled clinical trials. The bioactive compounds were obtained by the absorption, distribution, metabolism, and excretion processes with oral bioavailability (OB) and drug-likeness (DL) evaluation...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29231558/-impact-of-deqi-on-acupoint-effects-in-patients-with-primary-dysmenorrhea-a-systematic-review-of-randomized-controlled-trials
#18
REVIEW
Yafeng Wang, Junjun Sun, Zhuang Zhang, Huijuan Cao, Pei Wang, Minyi Zhao, Nijuan Hu, Guiwen Wu, Shangqing Hu, Jiang Zhu
The effects of deqi (arrival of qi) on acupoint effects in patients with primary dysmenorrhea (PD) were evaluated.Ten literature databases,including China National Knowledge Infrastructure (CNKI),VIP Database,Wanfang Database,Chinese Biomedical Literature Database (CBM),Cochrane Library CENTRAL,MEDLINE,Embase,AMED, CINAHL Plus,PsycINFO were selected.In addition,5 registers of ongoing trials,the reference lists of included articles and grey literature website OpenGrey were added.The search time was from date of database establishment to August 2016;no restrictions were made on language or status of publication...
July 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29231513/-application-of-data-mining-on-the-relationship-between-deqi-and-effect
#19
Qiuyin Pan, Liangxiao Ma, Yang Yang, Jiang Zhu
OBJECTIVE: To analyze the relationship between deqi and effect by data mining technique with retrieving clinical literature about acupuncture deqi since the founding of the country. METHODS: The modern computerization and data mining technologies were adopted to set up clinical literature about acupuncture deqi database. The relevant clinical literature was collected, screened, extracted, and statistical and correlation analyses were used so as to explore the relationship between deqi and effect...
June 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29231353/-efficacy-of-filiform-needle-manipulation-on-primary-dysmenorrhea-a-systematic-review
#20
Junjun Sun, Yafeng Wang, Zhuang Zhang, Huijuan Cao, Pei Wang, Minyi Zhao, Nijuan Hu, Guiwen Wu, Shangqing Hu, Jiang Zhu
The paper is a systematic review on the efficacy of acupuncture manipulation on primary dysmenorrhea. Ten medical literatures database at home and abroad were retrieved, including CNKI, VIP, CBM, WANFANG, MEDLINE, Cochrane, CENTRAL, CINAHL PLUS, EMBASE, AMED and PsycINFO, as well as 6 clinical trial registration platforms. All of randomized controlled trials (RCTs) on primary dysmenorrhea treated with different acupuncture manipulations were collected. The data were extracted by two persons. Finally, RevMa 5...
August 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
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